Leverage research EXCELLence and INNOVation potential of Instituto de Medicina Molecular (IMM) through translational biomedical research in immunity and infection.

Rezultaty

Re-evaluation of current state of IMM towards ERA priorities
Publications in the research field of immunity and infection of the Instituto de Medicina Molecular

A one-page statement that the task has been completed.

Acquisition of the pre-clinical molecular and imaging equipment
Organisation of thematic Workshops – first period

Organisation of thematic Workshops held during the first period

Organisation of thematic Workshops – second period

Organisation of thematic Workshops held during the second reporting period

Self-assessment after 2-year period of strategy implementation
Organisation of thematic Workshops – third period

Organisation of thematic Workshops held during the third reporting period

Launch of website
Development of the project logo/brand
Forum for overseas discussion in translational immunity and infection
Brochure and flyer development

Publikacje

Controlling the pandemic during the SARS-CoV-2 vaccination rollout

Autorzy: João Viana, Christiaan H. van Dorp, Ana Nunes, Manuel C. Gomes, Michiel van Boven, Mirjam E. Kretzschmar, Marc Veldhoen, Ganna Rozhnova
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-23938-8

Th17 Cells Require You to Chew before You Swallow

Autorzy: Marc Veldhoen
Opublikowane w: Immunity, Numer 46/1, 2017, Strona(/y) 8-10, ISSN 1074-7613
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2016.12.016

Seroprevalence of anti‐SARS‐CoV‐2 antibodies in COVID‐19 patients and healthy volunteers up to 6 months post disease onset

Autorzy: Patrícia Figueiredo‐Campos, Birte Blankenhaus, Catarina Mota, Andreia Gomes, Marta Serrano, Silvia Ariotti, Catarina Costa, Helena Nunes‐Cabaço, António M. Mendes, Pedro Gaspar, M. Conceição Pereira‐Santos, Fabiana Rodrigues, Jorge Condeço, M. Antonia Escoval, Matilde Santos, Mario Ramirez, José Melo‐Cristino, J. Pedro Simas, Eugenia Vasconcelos, Ângela Afonso, Marc Veldhoen
Opublikowane w: European Journal of Immunology, Numer 50/12, 2020, Strona(/y) 2025-2040, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202048970

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

Autorzy: Cristina C. Clement, Angelo D’Alessandro, Sangeetha Thangaswamy, Samantha Chalmers, Raquel Furtado, Sheila Spada, Giada Mondanelli, Federica Ianni, Sarah Gehrke, Marco Gargaro, Giorgia Manni, Luisa Carlota Lopez Cara, Peter Runge, Wanxia Li Tsai, Sinem Karaman, Jorge Arasa, Ruben Fernandez-Rodriguez, Amanda Beck, Antonio Macchiarulo, Massimo Gadina, Cornelia Halin, Francesca Fallarino, Mihaela S
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-24785-3

Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium

Autorzy: Juri Kazakevych, Jérémy Denizot, Anke Liebert, Mariana Portovedo, Mia Mosavie, Payal Jain, Claudia Stellato, Claire Fraser, Renan Oliveira Corrêa, Marina Célestine, Raphaël Mattiuz, Hanneke Okkenhaug, J. Ross Miller, Marco Aurélio Ramirez Vinolo, Marc Veldhoen, Patrick Varga-Weisz
Opublikowane w: Genome Biology, Numer 21/1, 2020, ISSN 1474-760X
Wydawca: BMC
DOI: 10.1186/s13059-020-01976-7

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

Autorzy: Anne-Katrien Stark, Elizabeth C. M. Davenport, Daniel T. Patton, Cheryl L. Scudamore, Bart Vanhaesebroeck, Marc Veldhoen, Oliver A. Garden, Klaus Okkenhaug
Opublikowane w: The Journal of Immunology, Numer 205/1, 2020, Strona(/y) 78-89, ISSN 0022-1767
Wydawca: American Association of Immunologists
DOI: 10.4049/jimmunol.2000043

Severe COVID-19 Recovery Is Associated with Timely Acquisition of a Myeloid Cell Immune-Regulatory Phenotype

Autorzy: Amelia C. Trombetta, Guilherme B. Farias, André M. C. Gomes, Ana Godinho-Santos, Pedro Rosmaninho, Carolina M. Conceição, Joel Laia, Diana F. Santos, Afonso R. M. Almeida, Catarina Mota, Andreia Gomes, Marta Serrano, Marc Veldhoen, Ana E. Sousa, Susana M. Fernandes
Opublikowane w: Frontiers in Immunology, Numer 12, 2021, ISSN 1664-3224
Wydawca: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2021.691725

Feeding immunity: skepticism, delicacies and delights

Autorzy: Marc Veldhoen, Henrique Veiga-Fernandes
Opublikowane w: Nature Immunology, Numer 16/3, 2015, Strona(/y) 215-219, ISSN 1529-2908
Wydawca: Nature Publishing Group
DOI: 10.1038/ni.3100

Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells

Autorzy: Cristina Ferreira, Leandro Barros, Marta Baptista, Birte Blankenhaus, André Barros, Patrícia Figueiredo-Campos, Špela Konjar, Alexandra Lainé, Nadine Kamenjarin, Ana Stojanovic, Adelheid Cerwenka, Hans C. Probst, Julien C. Marie, Marc Veldhoen
Opublikowane w: Nature Immunology, Numer 21/7, 2020, Strona(/y) 766-776, ISSN 1529-2908
Wydawca: Nature Publishing Group
DOI: 10.1038/s41590-020-0674-9

Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses

Autorzy: Eliseu Frank de Araújo, Nycolas Willian Preite, Marc Veldhoen, Flávio Vieira Loures, Vera Lúcia Garcia Calich
Opublikowane w: Scientific Reports, Numer 10/1, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-68322-6

Humoral Immune Response of SARS‐CoV ‐2–Infected Patients with Cancer: Influencing Factors and Mechanisms

Autorzy: Miguel Esperança‐Martins, Lisa Gonçalves, Inês Soares‐Pinho, Andreia Gomes, Marta Serrano, Birte Blankenhaus, Patrícia Figueiredo‐Campos, Ana Catarina‐Marques, Ana Castro‐Barbosa, Ana Cardoso, Pedro Antunes‐Meireles, Henrique Atalaia‐Barbacena, Pedro Gaspar, Patrícia Howell‐Monteiro, António Pais‐de‐Lacerda, Catarina Mota, Marc Veldhoen
Opublikowane w: The Oncologist, Numer 26/9, 2021, ISSN 1083-7159
Wydawca: AlphaMed Press Inc
DOI: 10.1002/onco.13828

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Autorzy: Rachel Fellows, Jérémy Denizot, Claudia Stellato, Alessandro Cuomo, Payal Jain, Elena Stoyanova, Szabina Balázsi, Zoltán Hajnády, Anke Liebert, Juri Kazakevych, Hector Blackburn, Renan Oliveira Corrêa, José Luís Fachi, Fabio Takeo Sato, Willian R. Ribeiro, Caroline Marcantonio Ferreira, Hélène Perée, Mariangela Spagnuolo, Raphaël Mattiuz, Csaba Matolcsi, Joana Guedes, Jonathan Clark, M
Opublikowane w: Nature Communications, Numer 9/1, 2018, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-017-02651-5

Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca2+ Entry in T Cells by Regulating miR-10a-5p

Autorzy: Shaqiu Zhang, Tamer Al-Maghout, Hang Cao, Lisann Pelzl, Madhuri S. Salker, Marc Veldhoen, Anchun Cheng, Florian Lang, Yogesh Singh
Opublikowane w: Frontiers in Immunology, Numer 10, 2019, ISSN 1664-3224
Wydawca: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2019.01737

Guidelines for the use of flow cytometry

Autorzy: Marc Veldhoen
Opublikowane w: Immunity, Inflammation and Disease, Numer 5/4, 2017, Strona(/y) 384-385, ISSN 2050-4527
Wydawca: WILEY
DOI: 10.1002/iid3.207

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Autorzy: Andrea Cossarizza, Hyun‐Dong Chang, Andreas Radbruch, Andreas Acs, Dieter Adam, Sabine Adam‐Klages, William W. Agace, Nima Aghaeepour, Mübeccel Akdis, Matthieu Allez, Larissa Nogueira Almeida, Giorgia Alvisi, Graham Anderson, Immanuel Andrä, Francesco Annunziato, Achille Anselmo, Petra Bacher, Cosima T. Baldari, Sudipto Bari, Vincenzo Barnaba, Joana Barros‐Martins, Luca Battistini, Wolfgan
Opublikowane w: European Journal of Immunology, Numer 49/10, 2019, Strona(/y) 1457-1973, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201970107

Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation

Autorzy: Verena Brucklacher-Waldert, Cristina Ferreira, Marisa Stebegg, Olivier Fesneau, Silvia Innocentin, Julien C. Marie, Marc Veldhoen
Opublikowane w: Cell Reports, Numer 19/11, 2017, Strona(/y) 2357-2370, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2017.05.052

Intestinal Barrier Interactions with Specialized CD8 T Cells

Autorzy: Špela Konjar, Cristina Ferreira, Birte Blankenhaus, Marc Veldhoen
Opublikowane w: Frontiers in Immunology, Numer 8, 2017, ISSN 1664-3224
Wydawca: FRONTIERS MEDIA SA, PO BOX 110, EPFL INNOVATION PARK, BUILDING I, LAUSANNE, 1015, SWITZERLAND
DOI: 10.3389/fimmu.2017.01281

Metabolic wiring of murine T cell and intraepithelial lymphocyte maintenance and activation

Autorzy: Marc Veldhoen, Birte Blankenhaus, Špela Konjar, Cristina Ferreira
Opublikowane w: European Journal of Immunology, 2018, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201646745

Oxygen starvation during T cell priming boosts cancer-killing potential

Autorzy: Špela Konjar, Birte Blankenhaus, Marc Veldhoen
Opublikowane w: Translational Cancer Research, Numer 7/S1, 2018, Strona(/y) S34-S37, ISSN 2218-676X
Wydawca: AME PUBL CO, FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG 00000, PEOPLES R CHINA
DOI: 10.21037/tcr.2017.12.07

Interleukin 17 is a chief orchestrator of immunity

Autorzy: Marc Veldhoen
Opublikowane w: Nature Immunology, Numer 18/6, 2017, Strona(/y) 612-621, ISSN 1529-2908
Wydawca: Nature Publishing Group
DOI: 10.1038/ni.3742

PD-1 and its ligand PD-L1 are progressively up-regulated on CD4 and CD8 T-cells in HIV-2 infection irrespective of the presence of viremia

Autorzy: Rita Tendeiro, Russell B. Foxall, António P. Baptista, Francisco Pinto, Rui S. Soares, Rita Cavaleiro, Emília Valadas, Perpétua Gomes, Rui M.M. Victorino, Ana E. Sousa
Opublikowane w: AIDS, Numer 02699370, 2012, Strona(/y) 1065-1071, ISSN 0269-9370
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/QAD.0b013e32835374db

Memory B-cell depletion is a feature of HIV-2 infection even in the absence of detectable viremia

Autorzy: Rita Tendeiro, Sofia Fernandes, Russell B. Foxall, José M. Marcelino, Nuno Taveira, Rui S. Soares, António P. Baptista, Rita Cavaleiro, Perpétua Gomes, Rui M.M. Victorino, Ana E. Sousa
Opublikowane w: AIDS, Numer 02699370, 2012, Strona(/y) 1607-1617, ISSN 0269-9370
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/QAD.0b013e3283568849

Gold nanoparticle-based fluorescence immunoassay for malaria antigen detection

Autorzy: Bassem S. S. Guirgis, Cláudia Sá e Cunha, Inês Gomes, Miguel Cavadas, Isabel Silva, Gonçalo Doria, Gregory L. Blatch, Pedro V. Baptista, Eulália Pereira, Hassan M. E. Azzazy, Maria M. Mota, Miguel Prudêncio, Ricardo Franco
Opublikowane w: Analytical and Bioanalytical Chemistry, Numer 16182642, 2012, Strona(/y) 1019-1027, ISSN 1618-2642
Wydawca: Springer Verlag
DOI: 10.1007/s00216-011-5489-y

Haemozoin detection in infected erythrocytes for Plasmodium falciparum malaria diagnosis—Prospects and limitations

Autorzy: Maria Rebelo, Howard M. Shapiro, Teresa Amaral, José Melo-Cristino, Thomas Hänscheid
Opublikowane w: Acta Tropica, Numer 0001706X, 2012, Strona(/y) 58-61, ISSN 0001-706X
Wydawca: Elsevier BV
DOI: 10.1016/j.actatropica.2012.03.005

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

Autorzy: A. C. Pena, N. Penacho, L. Mancio-Silva, R. Neres, J. D. Seixas, A. C. Fernandes, C. C. Romao, M. M. Mota, G. J. L. Bernardes, A. Pamplona
Opublikowane w: Antimicrobial Agents and Chemotherapy, Numer 00664804, 2012, Strona(/y) 1281-1290, ISSN 0066-4804
Wydawca: American Society for Microbiology
DOI: 10.1128/AAC.05571-11

PHYLOViZ: phylogenetic inference and data visualization for sequence based typing methods

Autorzy: Alexandre P Francisco, Cátia Vaz, Pedro T Monteiro, José Melo-Cristino, Mário Ramirez, João A Carriço
Opublikowane w: BMC Bioinformatics, Numer 14712105, 2012, Strona(/y) 87, ISSN 1471-2105
Wydawca: BioMed Central
DOI: 10.1186/1471-2105-13-87

Engagement of NKp30 on V 1 T cells induces the production of CCL3, CCL4, and CCL5 and suppresses HIV-1 replication

Autorzy: K. Hudspeth, M. Fogli, D. V. Correia, J. Mikulak, A. Roberto, S. Della Bella, B. Silva-Santos, D. Mavilio
Opublikowane w: Blood, Numer 00064971, 2012, Strona(/y) 4013-4016, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2011-11-390153

Differences between Macrolide-Resistant and -Susceptible Streptococcus pyogenes: Importance of Clonal Properties in Addition to Antibiotic Consumption

Autorzy: C. Silva-Costa, A. Friaes, M. Ramirez, J. Melo-Cristino
Opublikowane w: Antimicrobial Agents and Chemotherapy, Numer 00664804, 2012, Strona(/y) 5661-5666, ISSN 0066-4804
Wydawca: American Society for Microbiology
DOI: 10.1128/AAC.01133-12

Novel Potent Metallocenes against Liver Stage Malaria

Autorzy: J. Matos, F. P. da Cruz, E. Cabrita, J. Gut, F. Nogueira, V. E. do Rosario, R. Moreira, P. J. Rosenthal, M. Prudencio, P. Gomes
Opublikowane w: Antimicrobial Agents and Chemotherapy, Numer 00664804, 2012, Strona(/y) 1564-1570, ISSN 0066-4804
Wydawca: American Society for Microbiology
DOI: 10.1128/AAC.05345-11

Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance

Autorzy: Ana Friães, Francisco R Pinto, Catarina Silva-Costa, Mario Ramirez, José Melo-Cristino
Opublikowane w: BMC Microbiology, Numer 14712180, 2012, Strona(/y) 280, ISSN 1471-2180
Wydawca: BioMed Central
DOI: 10.1186/1471-2180-12-280

Monocyte activation is a feature of common variable immunodeficiency irrespective of plasma lipopolysaccharide levels

Autorzy: R. R. Barbosa, S. P. Silva, S. L. Silva, R. Tendeiro, A. C. Melo, E. Pedro, M. P. Barbosa, M. C. P. Santos, R. M. M. Victorino, A. E. Sousa
Opublikowane w: Clinical & Experimental Immunology, Numer 00099104, 2012, Strona(/y) 263-272, ISSN 0009-9104
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/j.1365-2249.2012.04620.x

CD8+ T Cells from Mice Transnuclear for a TCR that Recognizes a Single H-2Kb-Restricted MHV68 Epitope Derived from gB-ORF8 Help Control Infection

Autorzy: Sharvan Sehrawat, Oktay Kirak, Paul-Albert Koenig, Marisa K. Isaacson, Sofia Marques, Gunes Bozkurt, J. Pedro Simas, Rudolph Jaenisch, Hidde L. Ploegh
Opublikowane w: Cell Reports, Numer 22111247, 2012, Strona(/y) 461-471, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2012.03.009

Early skin immunological disturbance after Plasmodium-infected mosquito bites

Autorzy: Henrique Borges da Silva, Susana S. Caetano, Isadora Monteiro, Iván Gómez-Conde, Kirsten Hanson, Carlos Penha-Gonçalves, David N. Olivieri, Maria M. Mota, Cláudio R. Marinho, Maria R. D’Imperio Lima, Carlos E. Tadokoro
Opublikowane w: Cellular Immunology, Numer 00088749, 2012, Strona(/y) 22-32, ISSN 0008-8749
Wydawca: Academic Press
DOI: 10.1016/j.cellimm.2012.06.003

γδ T-cell conference 2012: Close encounters for the fifth time

Autorzy: Bruno Silva-Santos, Wolfgang W. A. Schamel, Paul Fisch, Matthias Eberl
Opublikowane w: European Journal of Immunology, Numer 00142980, 2012, Strona(/y) 3101-3105, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201270101

Driving IL-17+ γδ T-cell migration in allergic reactions: A new “inflammatory” role for the “homeostatic” chemokine CCL25

Autorzy: Bruno Silva-Santos
Opublikowane w: European Journal of Immunology, Numer 00142980, 2012, Strona(/y) 1097-1101, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201242545

Persistence of uropathogenic Escherichia coli strains in the host for long periods of time: relationship between phylogenetic groups and virulence factors

Autorzy: A. Narciso, F. Nunes, T. Amores, L. Lito, J. Melo-Cristino, A. Duarte
Opublikowane w: European Journal of Clinical Microbiology & Infectious Diseases, Numer 09349723, 2012, Strona(/y) 1211-1217, ISSN 0934-9723
Wydawca: Springer Verlag
DOI: 10.1007/s10096-011-1431-7

Innate recognition of malarial parasites by mammalian hosts

Autorzy: Peter Liehl, Maria M. Mota
Opublikowane w: International Journal for Parasitology, Numer 00207519, 2012, Strona(/y) 557-566, ISSN 0020-7519
Wydawca: Elsevier BV
DOI: 10.1016/j.ijpara.2012.04.006

Targeting the Liver Stage of Malaria Parasites: A Yet Unmet Goal

Autorzy: Tiago Rodrigues, Miguel Prudêncio, Rui Moreira, Maria M. Mota, Francisca Lopes
Opublikowane w: Journal of Medicinal Chemistry, Numer 00222623, 2012, Strona(/y) 995-1012, ISSN 0022-2623
Wydawca: American Chemical Society
DOI: 10.1021/jm201095h

Murine Gammaherpesvirus 68 LANA Acts on Terminal Repeat DNA To Mediate Episome Persistence

Autorzy: A. C. Habison, C. Beauchemin, J. P. Simas, E. J. Usherwood, K. M. Kaye
Opublikowane w: Journal of Virology, Numer 0022538X, 2012, Strona(/y) 11863-11876, ISSN 0022-538X
Wydawca: American Society for Microbiology
DOI: 10.1128/JVI.01656-12

T Cell Apoptosis and Induction of Foxp3+ Regulatory T Cells Underlie the Therapeutic Efficacy of CD4 Blockade in Experimental Autoimmune Encephalomyelitis

Autorzy: J. Duarte, N. Carrie, V. G. Oliveira, C. Almeida, A. Agua-Doce, L. Rodrigues, J. P. Simas, L. T. Mars, L. Graca
Opublikowane w: The Journal of Immunology, Numer 00221767, 2012, Strona(/y) 1680-1688, ISSN 0022-1767
Wydawca: American Association of Immunologists
DOI: 10.4049/jimmunol.1201269

Dominance of Serotype Ia among Group B Streptococci Causing Invasive Infections in Nonpregnant Adults in Portugal

Autorzy: E. R. Martins, J. Melo-Cristino, M. Ramirez
Opublikowane w: Journal of Clinical Microbiology, Numer 00951137, 2012, Strona(/y) 1219-1227, ISSN 0095-1137
Wydawca: American Society for Microbiology
DOI: 10.1128/JCM.05488-11

The split nature of tumor-infiltrating leukocytes

Autorzy: Telma Lança, Bruno Silva-Santos
Opublikowane w: OncoImmunology, Numer 21624011, 2012, Strona(/y) 717-725, ISSN 2162-4011
Wydawca: Landes Bioscience
DOI: 10.4161/onci.20068

Infection by Plasmodium changes shape and stiffness of hepatic cells

Autorzy: Peter Eaton, Vanessa Zuzarte-Luis, Maria M. Mota, Nuno C. Santos, Miguel Prudêncio
Opublikowane w: Nanomedicine: Nanotechnology, Biology and Medicine, Numer 15499634, 2012, Strona(/y) 17-19, ISSN 1549-9634
Wydawca: Elsevier BV
DOI: 10.1016/j.nano.2011.10.004

Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation

Autorzy: Adriana S. Albuquerque, José G. Marques, Susana L. Silva, Dario Ligeiro, Blythe H. Devlin, Jacques Dutrieux, Rémi Cheynier, Claudio Pignata, Rui M. M. Victorino, M. Louise Markert, Ana E. Sousa
Opublikowane w: PLoS ONE, Numer 19326203, 2012, Strona(/y) e37042, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0037042

A Novel Way to Grow Hemozoin-Like Crystals In Vitro and Its Use to Screen for Hemozoin Inhibiting Antimalarial Compounds

Autorzy: Vincent Thomas, Ana Góis, Bruce Ritts, Peter Burke, Thomas Hänscheid, Gerald McDonnell
Opublikowane w: PLoS ONE, Numer 19326203, 2012, Strona(/y) e41006, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0041006

Highly Dynamic Host Actin Reorganization around Developing Plasmodium Inside Hepatocytes

Autorzy: Carina S. S. Gomes-Santos, Maurice A. Itoe, Cristina Afonso, Ricardo Henriques, Rui Gardner, Nuno Sepúlveda, Pedro D. Simões, Helena Raquel, António Paulo Almeida, Luis F. Moita, Friedrich Frischknecht, Maria M. Mota
Opublikowane w: PLoS ONE, Numer 19326203, 2012, Strona(/y) e29408, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0029408

RET/GFRα Signals Are Dispensable for Thymic T Cell Development In Vivo

Autorzy: Afonso Rocha Martins Almeida, Sílvia Arroz-Madeira, Diogo Fonseca-Pereira, Hélder Ribeiro, Reena Lasrado, Vassilis Pachnis, Henrique Veiga-Fernandes
Opublikowane w: PLoS ONE, Numer 19326203, 2012, Strona(/y) e52949, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0052949

PRIMACINS, N-cinnamoyl-primaquine conjugates, with improved liver-stage antimalarial activity

Autorzy: Bianca Pérez, Cátia Teixeira, Inês S. Albuquerque, Jiri Gut, Philip J. Rosenthal, Miguel Prudêncio, Paula Gomes
Opublikowane w: MedChemComm, Numer 20402503, 2012, Strona(/y) 1170, ISSN 2040-2503
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c2md20113e

Differential RET Signaling Pathways Drive Development of the Enteric Lymphoid and Nervous Systems

Autorzy: A. Patel, N. Harker, L. Moreira-Santos, M. Ferreira, K. Alden, J. Timmis, K. Foster, A. Garefalaki, P. Pachnis, P. Andrews, H. Enomoto, J. Milbrandt, V. Pachnis, M. C. Coles, D. Kioussis, H. Veiga-Fernandes
Opublikowane w: Science Signaling, Numer 19379145, 2012, Strona(/y) ra55-ra55, ISSN 1937-9145
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/scisignal.2002734

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Autorzy: E. R. Derbyshire, M. Prudencio, M. M. Mota, J. Clardy
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 00278424, 2012, Strona(/y) 8511-8516, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1118370109

Serotype changes in adult invasive pneumococcal infections in Portugal did not reduce the high fraction of potentially vaccine preventable infections

Autorzy: Andreia N. Horácio, Jorge Diamantino-Miranda, Sandra I. Aguiar, Mário Ramirez, José Melo-Cristino
Opublikowane w: Vaccine, Numer 0264410X, 2012, Strona(/y) 218-224, ISSN 0264-410X
Wydawca: Elsevier BV
DOI: 10.1016/j.vaccine.2011.11.022

B7-CD28 Costimulatory Signals Control the Survival and Proliferation of Murine and Human T Cells via IL-2 Production

Autorzy: J. C. Ribot, A. deBarros, L. Mancio-Silva, A. Pamplona, B. Silva-Santos
Opublikowane w: The Journal of Immunology, Numer 00221767, 2012, Strona(/y) 1202-1208, ISSN 0022-1767
Wydawca: American Association of Immunologists
DOI: 10.4049/jimmunol.1200268

Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease

Autorzy: Sandra I. Aguiar, José Melo-Cristino, Mário Ramirez
Opublikowane w: Vaccine, Numer 0264410X, 2012, Strona(/y) 5487-5490, ISSN 0264-410X
Wydawca: Elsevier BV
DOI: 10.1016/j.vaccine.2012.06.062

Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug

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Wydawca: Cell Press
DOI: 10.1016/j.cub.2019.01.055

Guidelines for the use of flow cytometry and cell sorting in immunological studies *

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Opublikowane w: European Journal of Immunology, Numer 47/10, 2017, Strona(/y) 1584-1797, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201646632

Quantification of Sporozoite Invasion, Migration, and Development by Microscopy and Flow Cytometry

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Opublikowane w: Malaria, 2013, Strona(/y) 385-400, ISBN 978-1-62703-026-7
Wydawca: Humana Press
DOI: 10.1007/978-1-62703-026-7_27

Differentiation and Activation of γδ T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors

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Opublikowane w: Crossroads Between Innate and Adaptive Immunity IV, 2013, Strona(/y) 95-105, ISBN 978-1-4614-6217-0
Wydawca: Springer New York
DOI: 10.1007/978-1-4614-6217-0_11

Endemic SARS-CoV-2 will maintain post-pandemic immunity

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Opublikowane w: Nature Reviews Immunology, Numer 21/3, 2021, Strona(/y) 131-132, ISSN 1474-1733
Wydawca: Nature Publishing Group
DOI: 10.1038/s41577-020-00493-9

Academic labs supporting COVID‐19 diagnostics

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Opublikowane w: European Journal of Immunology, Numer 51/1, 2021, Strona(/y) 13-16, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202170015

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