Self-Organising Capacity of Stem Cells during Implantation and Early Post-implantation Development: Implications for Human Development

Publikacje

Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation

Autorzy: Christodoulou N, Weberling A, Strathdee D, Anderson KI, Timpson P and Zernicka-Goetz M.
Opublikowane w: Nature Communications, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-11482-5

Trophectoderm mechanics direct epiblast shape upon embryo implantation

Autorzy: Weberling A and Zernicka-Goetz M.
Opublikowane w: Cell Reports, 2021, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2020.108655

Embryo Size Regulates the Timing and Mechanism of Pluripotent Tissue Morphogenesis.

Autorzy: Orietti LC, Rosa VS, Antonica F, Kyprianou C, Mansfield W, Marques-Souza H, Shahbazi MN and Zernicka-Goetz M.
Opublikowane w: Stem Cell Reports, 2020, ISSN 2213-6711
Wydawca: Cell Press
DOI: 10.1016/j.stemcr.2020.09.004

Concerted cell divisions in embryonic visceral endoderm guide anterior visceral endoderm migration

Autorzy: Francesco Antonica; Lorenzo Carlo Orietti; Richard L. Mort; Magdalena Zernicka-Goetz
Opublikowane w: Developmental Biology, Numer 3, 2019, ISSN 0012-1606
Wydawca: Academic Press
DOI: 10.1016/j.ydbio.2019.03.016

BMP signalling is required for extra-embryonic ectoderm development during pre-to-post-implantation transition of the mouse embryo.

Autorzy: Sozen B, Demir N and Zernicka-Goetz M
Opublikowane w: Developmental Biology, 2021, ISSN 0012-1606
Wydawca: Academic Press
DOI: 10.1016/j.ydbio.2020.11.005

Basement membrane remodelling regulates mouse embryogenesis

Autorzy: Kyprianou C, Christodoulou N, Hamilton RS, Nahaboo W, Boomgaard DS, Amadei G, Migeotte I and Zernicka-Goetz M.
Opublikowane w: Nature, 2020, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-020-2264-2

Reconstructing aspects of human embryogenesis with pluripotent stem cells.

Autorzy: Sozen B, Jorgensen V, Weatherbee BAT, Chen S, Zhu M, Zernicka-Goetz M.
Opublikowane w: Nature Communications, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-25853-4

Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism

Autorzy: Singla S, Iwamoto-Stohl LK, Zhu M and Zernicka-Goetz M.
Opublikowane w: Nature Communications, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-020-16796-3

Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro

Autorzy: Amadei G, Lau KYC, De Jonghe J, Gantner CW, Sozen B, Chan C, Zhu M, Kyprianou C, Hollfelder F and Zernicka-Goetz M.
Opublikowane w: Developmental Cell, 2021, ISSN 1878-1551
Wydawca: Cell Press
DOI: 10.1016/j.devcel.2020.12.004

Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition

Autorzy: Molè MA, Weberling A, Fässler R, Campbell A, Fishel S and Zernicka-Goetz M.
Opublikowane w: Cell Reports, 2021, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2021.108834

Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid.

Autorzy: Berna Sozen; Berna Sozen; Andy Cox; Andy Cox; Joachim De Jonghe; Min Bao; Florian Hollfelder; David M. Glover; David M. Glover; Magdalena Zernicka-Goetz; Magdalena Zernicka-Goetz
Opublikowane w: Developmental Cell, 2019, ISSN 1878-1551
Wydawca: Cell Press
DOI: 10.17863/cam.47244

Deconstructing and reconstructing the mouse and human early embryo

Autorzy: Marta N. Shahbazi, Magdalena Zernicka-Goetz
Opublikowane w: Nature Cell Biology, Numer 20/8, 2018, Strona(/y) 878-887, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-018-0144-x

In vitro generation of mouse polarized embryo-like structures from embryonic and trophoblast stem cells

Autorzy: Sarah Ellys Harrison, Berna Sozen, Magdalena Zernicka-Goetz
Opublikowane w: Nature Protocols, Numer 13/7, 2018, Strona(/y) 1586-1602, ISSN 1754-2189
Wydawca: Nature Publishing Group
DOI: 10.1038/s41596-018-0005-x

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures

Autorzy: Berna Sozen, Gianluca Amadei, Andy Cox, Ran Wang, Ellen Na, Sylwia Czukiewska, Lia Chappell, Thierry Voet, Geert Michel, Naihe Jing, David M. Glover, Magdalena Zernicka-Goetz
Opublikowane w: Nature Cell Biology, Numer 20/8, 2018, Strona(/y) 979-989, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-018-0147-7

Pluripotent state transitions coordinate morphogenesis in mouse and human embryos

Autorzy: Marta N. Shahbazi, Antonio Scialdone, Natalia Skorupska, Antonia Weberling, Gaelle Recher, Meng Zhu, Agnieszka Jedrusik, Liani G. Devito, Laila Noli, Iain C. Macaulay, Christa Buecker, Yakoub Khalaf, Dusko Ilic, Thierry Voet, John C. Marioni, Magdalena Zernicka-Goetz
Opublikowane w: Nature, 2017, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/nature24675

Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro

Autorzy: Sarah Ellys Harrison, Berna Sozen, Neophytos Christodoulou, Christos Kyprianou, Magdalena Zernicka-Goetz
Opublikowane w: Science, Numer 356/6334, 2017, Strona(/y) eaal1810, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.aal1810

Synthetic embryos complete gastrulation to neurulation and organogenesis.

Autorzy: Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen DY, Aguilera-Castrejon A, Hanna JH, Elowitz M, Hollfelder F, Shendure J, Glover DM, Zernicka-Goetz M.
Opublikowane w: Nature, 2022, ISSN 1476-4687
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-022-05246-3

An in vitro stem cell model of human epiblast and yolk sac interaction

Autorzy: Mackinlay K, Weatherbee BAT, Rosa VS, Handford CE, Hudson G, Coorens T, Pereira LV, Behjati S, Vallier L, Shahbazi M and Zernicka-Goetz M.
Opublikowane w: eLife, 2021, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.63930

Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation

Autorzy: Christodoulou N, Kyprianou C, Weberling A, Wang R, Cui G, Peng G, Jing N and Zernicka-Goetz M.
Opublikowane w: Nature Cell Biology, 2018, ISSN 1476-4679
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-018-0211-3

Prawa własności intelektualnej

method and medium composition used to generate stem cell–derived embryos

Numer wniosku/publikacji: UK 1615343.9
Data: 2017-05-01

method and medium composition used to generate stem cell–derived embryos

Numer wniosku/publikacji: UK 1615343.9
Data: 2017-05-01

method and medium composition used to generate stem cell–derived embryos

Numer wniosku/publikacji: UK 1615343.9
Data: 2017-05-01

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