Single-Molecule And Structural Studies Of ATP-Dependent Chromatin Remodelling

Pubblicazioni

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

Autori: Luka Bacic; Guillaume Gaullier; Anton Sabantsev; Laura C. Lehmann; Klaus Brackmann; Despoina Dimakou; Mario Halic; Graeme Hewitt; Simon J. Boulton; Sebastian Deindl
Pubblicato in: eLife, Numero 2, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.71420

Spatiotemporally controlled generation of NTPs for single-molecule studies

Autori: Anton Sabantsev, Guanzhong Mao, Javier Aguirre Rivera, Mikhail Panfilov, Anatolii Arseniev, Oanh Ho, Mikhail Khodorkovskiy & Sebastian Deindl
Pubblicato in: Nature Chemical Biology, Numero 15524469, 2022, ISSN 1552-4469
Editore: Nature
DOI: 10.1038/s41589-022-01100-9

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Autori: Graeme Hewitt, Valerie Borel, Sandra Segura-Bayona, Tohru Takaki, Phil Ruis, Roberto Bellelli, Laura C. Lehmann, Lucia Sommerova, Aleksandra Vancevska, Antonia Tomas-Loba, Kang Zhu, Christopher Cooper, Kasper Fugger, Harshil Patel, Robert Goldstone, Deborah Schneider-Luftman, Ellie Herbert, Gordon Stamp, Rachel Brough, Stephen Pettitt, Christopher J. Lord, Stephen C. West, Ivan Ahel, Dragana Ahel,
Pubblicato in: Molecular Cell, Numero 81/4, 2021, Pagina/e 767-783.e11, ISSN 1097-2765
Editore: Cell Press
DOI: 10.1016/j.molcel.2020.12.006

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

Autori: Laura C. Lehmann, Luka Bacic, Graeme Hewitt, Klaus Brackmann, Anton Sabantsev, Guillaume Gaullier, Sofia Pytharopoulou, Gianluca Degliesposti, Hanneke Okkenhaug, Song Tan, Alessandro Costa, J. Mark Skehel, Simon J. Boulton, Sebastian Deindl
Pubblicato in: Cell Reports, Numero 33/12, 2020, Pagina/e 108529, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2020.108529

Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI

Autori: Kalle Kipper, Nadja Eremina, Emil Marklund, Sumera Tubasum, Guanzhong Mao, Laura Christina Lehmann, Johan Elf, Sebastian Deindl
Pubblicato in: PLOS ONE, Numero 13/6, 2018, Pagina/e e0198416, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0198416

New enzymatic and mass spectrometric methodology for the selective investigation of gut microbiota-derived metabolites

Autori: Caroline Ballet, Mário S. P. Correia, Louis P. Conway, Theresa L. Locher, Laura C. Lehmann, Neeraj Garg, Miroslav Vujasinovic, Sebastian Deindl, J.-Matthias Löhr, Daniel Globisch
Pubblicato in: Chemical Science, Numero 9/29, 2018, Pagina/e 6233-6239, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/c8sc01502c

Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

Autori: Laura C. Lehmann, Graeme Hewitt, Shintaro Aibara, Alexander Leitner, Emil Marklund, Sarah L. Maslen, Varun Maturi, Yang Chen, David van der Spoel, J. Mark Skehel, Aristidis Moustakas, Simon J. Boulton, Sebastian Deindl
Pubblicato in: Molecular Cell, Numero 68/5, 2017, Pagina/e 847-859.e7, ISSN 1097-2765
Editore: Cell Press
DOI: 10.1016/j.molcel.2017.10.017

Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

Autori: Anton Sabantsev, Robert F. Levendosky, Xiaowei Zhuang, Gregory D. Bowman, Sebastian Deindl
Pubblicato in: Nature Communications, Numero 10/1, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-019-09657-1

The ribosomal protein S1-dependent standby site in tisB mRNA consists of a single-stranded region and a 5′ structure element

Autori: Cédric Romilly, Sebastian Deindl, E. Gerhart H. Wagner
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 116/32, 2019, Pagina/e 15901-15906, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1904309116

Sequence specificity in DNA binding is mainly governed by association

Autori: E. Marklund, G. Mao, J. Yan, S. Zikrin, E. Abdurakhmanov, S. Deindl, J. Elf
Pubblicato in: Science, Numero Vol 375, Numero 6579, 2022, Pagina/e 442-445, ISSN 1095-9203
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.abg7427

DNA surface exploration and operator bypassing during target search

Autori: Emil Marklund, Brad van Oosten, Guanzhong Mao, Elias Amselem, Kalle Kipper, Anton Sabantsev, Andrew Emmerich, Daniel Globisch, Xuan Zheng, Laura C. Lehmann, Otto G. Berg, Magnus Johansson, Johan Elf, Sebastian Deindl
Pubblicato in: Nature, Numero 583/7818, 2020, Pagina/e 858-861, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-2413-7

Recent advances in single-molecule fluorescence microscopy render structural biology dynamic

Autori: Luka Bacic, Anton Sabantsev, Sebastian Deindl
Pubblicato in: Current Opinion in Structural Biology, Numero 65, 2020, Pagina/e 61-68, ISSN 0959-440X
Editore: Elsevier BV
DOI: 10.1016/j.sbi.2020.05.006

Remodeling the genome with DNA twists

Autori: GREGORY D. BOWMAN AND SEBASTIAN DEINDL
Pubblicato in: Science, Numero 10959203, 2019, Pagina/e 35-36, ISSN 1095-9203
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aay4317

È in corso la ricerca di dati su OpenAIRE...

Pubblicazioni

Condividi questa pagina

Scarica