Targeting the transcriptional landscape in infant AML

Publikacje

Down syndrome and leukemia: from basic mechanisms to clinical advances

Autorzy: André Baruchel, Jean-Pierre Bourquin, John Crispino, Sergi Cuartero, Henrik Hasle, Johann Hitzler, Jan-Henning Klusmann, Shai Izraeli, Andrew A. Lane, Sébastien Malinge, Karen R. Rabin Irene Roberts, Sandra Ryeom, Sarah K. Tasian, Elvin Wagenblast
Opublikowane w: Haematologica, 2023, ISSN 1592-8721
Wydawca: Ferrata-Storti Foundation
DOI: 10.3324/haematol.2023.283225

Characterization of naked mole-rat hematopoiesis reveals unique stem and progenitor cell patterns and neotenic traits

Autorzy: Stephan Emmrich, Alexandre Trapp, Frances Tolibzoda Zakusilo, Maggie E Straight, Albert K Ying, Alexander Tyshkovskiy, Marco Mariotti, Spencer Gray, Zhihui Zhang, Michael G Drage, Masaki Takasugi, Jan-Henning Klusmann, Vadim N Gladyshev, Andrei Seluanov, Vera Gorbunova
Opublikowane w: The EMBO Journal, Numer 41, 2022, Strona(/y) e109694, ISSN 0261-4189
Wydawca: Nature Publishing Group
DOI: 10.15252/embj.2021109694

Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents

Autorzy: Andrew D.J. Pearson, C.Michel Zwaan, E.Anders Kolb, Dominik Karres, Julie Guillot, Su Young Kim, Lynley Marshall, Sarah K. Tasian, Malcolm Smith, Todd Cooper, Peter C. Adamson, Elly Barry, Bouchra Benettaib, Florence Binlich, Anne Borgman, Erica Brivio, Renaud Capdeville, David Delgado, Douglas Faller, Linda Fogelstrand, Paula Goodman Fraenkel, Henrik Hasle, Delphine Heenen, Gertjan Kaspers, Mark
Opublikowane w: European Journal of Cancer, Numer 136, 2020, Strona(/y) 116-129, ISSN 0959-8049
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2020.04.038

Responses to SARS-CoV-2 Vaccination in Young Patients with Anti-CD19 Chimeric Antigen Receptor T Cell-Induced B Cell Aplasia

Autorzy: Andrea Jarisch, Eliza Wiercinska, Sabine Huenecke, Melanie Bremm, Claudia Cappel, Julian Hauler, Eva Rettinger, Jan Soerensen, Helen Hellstern, Jan-Henning Klusmann, Sandra Ciesek, Halvard Bonig, Peter Bader
Opublikowane w: Transplantation and Cellular Therapy, Numer 28/7, 2022, Strona(/y) 366.e1-366.e7, ISSN 2666-6367
Wydawca: American Societyfor Transplantationand Cellular Therapy, Elsevir
DOI: 10.1016/j.jtct.2022.04.017

The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis

Autorzy: Oriol Alejo-Valle, Karoline Weigert, Raj Bhayadia, Michelle Ng, Hasan Issa, Christoph Beyer, Stephan Emmrich, Konstantin Schuschel, Christian Ihling, Andrea Sinz, Martin Zimmermann, Claudia Wickenhauser, Marius Flasinski, Eniko Regenyi, Maurice Labuhn, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
Opublikowane w: Blood, Numer 139/5, 2022, Strona(/y) 651-665, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood.2021012231

The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

Autorzy: Cornelis M van Tilburg, Elke Pfaff, Kristian W Pajtler, Karin P S Langenberg, Petra Fiesel, Barbara C Jones, Gnana Prakash Balasubramanian, Sebastian Stark, Pascal D Johann, Mirjam Blattner-Johnson, Kathrin Schramm, Nicola Dikow, Steffen Hirsch, Christian Sutter, Kerstin Grund, Arend von Stackelberg, Andreas E Kulozik, Andrej Lissat, Arndt Borkhardt, Roland Meisel, Dirk Reinhardt, Jan-Henning Klus
Opublikowane w: Cancer Discovery, Numer 11, 2021, Strona(/y) 2764-2779, ISSN 2159-8274
Wydawca: American Association for Cancer Research Inc.
DOI: 10.1158/2159-8290.cd-21-0094

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

Autorzy: Michelle Ng, Lonneke Verboon, Hasan Issa, Raj Bhayadia, Marit Willemijn Vermunt, Robert Winkler, Leah Schüler, Oriol Alejo, Konstantin Schuschel, Eniko Regenyi, Dorit Borchert, Michael Heuser, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl. Jan-Henning Klusmann
Opublikowane w: iScience, 2023, ISSN 2589-0042
Wydawca: Elsevir
DOI: 10.1016/j.isci.2023.107844

Recommendations for Diagnosis and Treatment of Children with Transient Abnormal Myelopoiesis (TAM) and Myeloid Leukemia in Down Syndrome (ML-DS)

Autorzy: Sina Al-Kershi, Richard Golnik, Marius Flasinski, Katharina Waack, Mareike Rasche, Ursula Creutzig, Michael Dworzak, Dirk Reinhardt, Jan-Henning Klusmann
Opublikowane w: Klinische Pädiatrie, Numer 6, 2021, Strona(/y) 267-277, ISSN 0300-8630
Wydawca: Georg Thieme Verlag
DOI: 10.1055/a-1532-2016

Leukoreductive response to the combination of sorafenib and chemotherapy in hyperleukocytosis of FLT3-ITD mutated pediatric AML

Autorzy: Franziska Schmidt, Miriam Erlacher, Charlotte Niemeyer, Dirk Reinhardt, Jan-Henning Klusmann
Opublikowane w: Frontiers in Pediatrics, Numer 10, 2022, ISSN 2296-2360
Wydawca: Frontiers Media
DOI: 10.3389/fped.2022.1046586

Biology-Driven Approaches to Prevent and Treat Relapse of Myeloid Neoplasia after Allogeneic Hematopoietic Stem Cell Transplantation

Autorzy: Robert Zeiser, Dietrich W Beelen, Wolfgang Bethge, Martin Bornhäuser, Gesine Bug, Andreas Burchert, Maximilian Christopeit, Justus Duyster, Jürgen Finke, Armin Gerbitz, Jan Henning Klusmann, Guido Kobbe, Michael Lübbert, Carsten Müller-Tidow, Uwe Platzbecker, Wolf Rösler, Martin Sauer, Christoph Schmid, Thomas Schroeder, Mathias Stelljes, Nicolaus Kröger, Lutz P Müller
Opublikowane w: Biology of Blood and Marrow Transplantation, Numer 25/4, 2019, Strona(/y) e128-e140, ISSN 1083-8791
Wydawca: Elsevier BV
DOI: 10.1016/j.bbmt.2019.01.016

Monitoring of Circulating CAR T Cells: Validation of a Flow Cytometric Assay, Cellular Kinetics, and Phenotype Analysis Following Tisagenlecleucel

Autorzy: Andreas Peinelt, Melanie Bremm, Hermann Kreyenberg, Claudia Cappel, Julia Banisharif-Dehkordi, Stephanie Erben, Eva Rettinger, Andrea Jarisch, Roland Meisel, Paul-Gerhardt Schlegel, Olaf Beck, Gesine Bug, Jan-Henning Klusmann, Thomas Klingebiel, Sabine Huenecke, Peter Bader
Opublikowane w: Frontiers in Immunology, Numer 13, 2022, ISSN 1664-3224
Wydawca: Frontiers Media
DOI: 10.3389/fimmu.2022.830773

ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma

Autorzy: Catrin Heim, Laura M. Moser, Herman Kreyenberg, Halvard B. Bonig, Torsten Tonn, Winfried S. Wels, Elise Gradhand, Evelyn Ullrich, Michael T. Meister, Marian Groot Koerkamp, Frank C. P. Holstege, Jarno Drost, Jan-Henning Klusmann, Peter Bader, Michael Merker, Eva Rettinger
Opublikowane w: Frontiers in Immunology, Numer 14, 2023, ISSN 1664-3224
Wydawca: Frontiers
DOI: 10.3389/fimmu.2023.1228894

Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias

Autorzy: Sandra Cantilena, Luca Gasparoli, Deepali Pal, Olaf Heidenreich, Jan-Henning Klusmann, Joost H. A. Martens, Alexandre Faille, Alan J. Warren, Mawar Karsa, Ruby Pandher, Klaartje Somers, Owen Williams, Jasper de Boer
Opublikowane w: Clinical and Translational Medicine, Numer 12/6, 2022, Strona(/y) e933, ISSN 2001-1326
Wydawca: Wiley
DOI: 10.1002/ctm2.933

Guideline for management of non-Down syndrome neonates with a myeloproliferative disease on behalf of the I-BFM AML Study Group and EWOG-MDS

Autorzy: Eline J.M. Bertrums, C. Michel Zwaan, Daisuke Hasegawa, Valerie de Haas, Dirk N. Reinhardt, Franco Locatelli, Barbara de Moerloose, Michael Dworzak, Arjan Buijs, Petr Smisek, Alexandra Kolenova, Cornelis Jan Pronk, Jan-Henning Klusmann, Ana Carboné, Alina Ferster, Evangelia Antoniou, Soheil Meshinchi, Susana C. Raimondi, Charlotte M. Niemeyer, Henrik Hasle, Marry M. van den Heuvel-Eibrink, Bianca
Opublikowane w: Haematologica, Numer 107/3, 2022, Strona(/y) 759-764, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2021.279507

Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukaemia

Autorzy: Milica Miladinovic, Jan-Henning Klusmann
Opublikowane w: British Journal of Haematology, Numer 202/4, 2023, Strona(/y) 713-714, ISSN 1365-2141
Wydawca: Wiley-Blackwell
DOI: 10.1111/bjh.18911

Segregated by Wealth, Health, and Development: An Analysis of Pre-School Child Health in a Medium- Sized German City

Autorzy: Karoline Wagner, Andreas Wienke, Christine Gröger, Jan-Henning Klusmann, Amand Führer
Opublikowane w: Children (Basel), Numer 10/5, 2023, Strona(/y) 865, ISSN 2227-9067
Wydawca: Basel: MDPI AG, 2014-
DOI: 10.3390/children10050865

Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro

Autorzy: Rebecca Pötschke, Gerrit Gielen, Torsten Pietsch, Christof Kramm, Jan-Henning Klusmann, Stefan Hüttelmaier, Caspar D Kühnöl
Opublikowane w: Pediatric Research, Numer 87, 2020, Strona(/y) 669–676, ISSN 0031-3998
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1038/s41390-019-0628-9

Donor-type red blood cell transfusion to deplete isoagglutinins prior to allogeneic stem cell transplantation from ABO major incompatible bone marrow donors

Autorzy: Andrea Jarisch, Emilia Salzmann-Manrique, Jan Soerensen, Gudrun Sach, Eva Rettinger, Andre Willasch, Shahrzad Bakhtiar, Dieter Klarmann, Susanne Bräuninger, Laura Moser, Julia Fekadu, Martin Hutter, Thomas Klingebiel, Jan-Henning Klusmann, Peter Bader, Halvard Bonig
Opublikowane w: British Journal of Haematology, Numer 201/6, 2023, Strona(/y) 1159-1168, ISSN 1365-2141
Wydawca: Wiley-Blackwell
DOI: 10.1111/bjh.18761

Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia

Autorzy: Raj Bhayadia, Kathrin Krowiorz, Nadine Haetscher, Razan Jammal, Stephan Emmrich, Askar Obulkasim, Jan Fiedler, Adrian Schwarzer, Arefeh Rouhi, Michael Heuser, Susanne Wingert, Sabrina Bothur, Konstanze Döhner, Tobias Mätzig, Michelle Ng, Dirk Reinhardt, Hartmut Döhner, C. Michel Zwaan, Marry van den Heuvel Eibrink, Dirk Heckl, Maarten Fornerod, Thomas Thum, R. Keith Humphries, Michael A. Rieger
Opublikowane w: Journal of Clinical Oncology, Numer 36/10, 2018, Strona(/y) 1007-1016, ISSN 0732-183X
Wydawca: American Society of Clinical Oncology
DOI: 10.1200/jco.2017.75.2204

Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications

Autorzy: Maurice Labuhn, Felix F Adams, Michelle Ng, Sabine Knoess, Axel Schambach, Emmanuelle M Charpentier, Adrian Schwarzer, Juan L Mateo, Jan-Henning Klusmann, Dirk Heckl
Opublikowane w: Nucleic Acids Research, Numer 46/3, 2017, Strona(/y) 1375-1385, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkx1268

Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study

Autorzy: Marius Flasinski, Kira Scheibke, Martin Zimmermann, Ursula Creutzig, Katarina Reinhardt, Femke Verwer, Valerie de Haas, Vincent H. J. van der Velden, Christine von Neuhoff, C. Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusmann
Opublikowane w: Blood Advances, Numer 2/13, 2018, Strona(/y) 1532-1540, ISSN 2473-9529
Wydawca: American Society of Hematology
DOI: 10.1182/bloodadvances.2018018945

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome

Autorzy: Maurice Labuhn, Kelly Perkins, Sören Matzk, Leila Varghese, Catherine Garnett, Elli Papaemmanuil, Marlen Metzner, Alison Kennedy, Vyacheslav Amstislavskiy, Thomas Risch, Raj Bhayadia, David Samulowski, David Cruz Hernandez, Bilyana Stoilova, Valentina Iotchkova, Udo Oppermann, Carina Scheer, Kenichi Yoshida, Adrian Schwarzer, Jeffrey W. Taub, John D. Crispino, Mitchell J. Weiss, Yasuhide Hayashi,
Opublikowane w: Cancer Cell, Numer 36/2, 2019, Strona(/y) 123-138.e10, ISSN 1535-6108
Wydawca: Cell Press
DOI: 10.1016/j.ccell.2019.06.007

The Regulatory Roles of Long Noncoding RNAs in Acute Myeloid Leukemia

Autorzy: Michelle Ng, Dirk Heckl, Jan-Henning Klusmann
Opublikowane w: Frontiers in Oncology, Numer 9, 2019, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2019.00570

The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A-rearranged leukemia

Autorzy: Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann
Opublikowane w: Blood Advances, Numer 3/24, 2019, Strona(/y) 4252-4263, ISSN 2473-9529
Wydawca: American Society of Hematology
DOI: 10.1182/bloodadvances.2019032029

The long non-coding RNA Cancer Susceptibility 15 is induced by Isocitrate Dehydrogenase mutations and maintains an immature phenotype in adult acute myeloid leukemia

Autorzy: Sarah Grasedieck, Christoph Ruess, Kathrin Krowiorz, Susanne Lux, Nicole Pochert, Adrian Schwarzer, Jan-Henning Klusmann, Mojca Jongen-Lavrencic, Tobias Herold, Lars Bullinger, Jonathan R. Pollack, Arefeh Rouhi, Florian Kuchenbauer
Opublikowane w: Haematologica, 2020, Strona(/y) haematol.2019.235291, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2019.235291

Molecular Approaches to Treating Pediatric Leukemias

Autorzy: Michaela Kuhlen, Jan-Henning Klusmann, Jessica I. Hoell
Opublikowane w: Frontiers in Pediatrics, Numer 7, 2019, ISSN 2296-2360
Wydawca: Frontiers Media SA
DOI: 10.3389/fped.2019.00368

Combining LSD1 and JAK- STAT inhibition targets Down syndrome-associated myeloid leukemia at its core

Autorzy: Juliane Grimm, Raj Bhayadia, Lucie Gack, Dirk Heckl, Jan-Henning Klusmann
Opublikowane w: Leukemia, Numer 36, 2022, Strona(/y) 1926–1930, ISSN 1476-5551
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-022-01603-3

IRAK1/4 inhibitors in AML/MDS

Autorzy: Hannah J. Uckelmann, Jan-Henning Klusmann
Opublikowane w: Blood, Numer 142/11, 2023, Strona(/y) 945-946, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood.2023020812

Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias

Autorzy: Hasan Issa, Raj Bhayadia, Robert Winkler, Laura Elise Swart, Dirk Heckl, Jan-Henning Klusmann
Opublikowane w: Leukemia, Numer 37/7, 2023, Strona(/y) 1583-1587, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-023-01937-6

Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation

Autorzy: Julius Lukes, Petr Danek, Oriol Alejo-Valle, Eliska Potuckova, Ondrej Gahura, Dirk Heckl, Julia Starkova, Jan Stary, Ester Mejstrikova, Meritxell Alberich-Jorda, Jan Zuna, Jan Trka, Jan-Henning Klusmann, Marketa Zaliova
Opublikowane w: Leukemia, Numer 34/9, 2020, Strona(/y) 2503-2508, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-020-0769-1

Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre‐excitation syndrome

Autorzy: Tim Niehues, Tuba Turul Özgür, Marie Bickes, Rebekka Waldmann, Jennifer Schöning, Jan Bräsen, Christian Hagel, Matthias Ballmaier, Jan‐Henning Klusmann, Alexandra Niedermayer, Ulrich Pannicke, Anselm Enders, Gregor Dückers, Kathrin Siepermann, Julyia Hempel, Klaus Schwarz, Dorothee Viemann
Opublikowane w: European Journal of Immunology, Numer 50/7, 2020, Strona(/y) 1078-1080, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201948504

Longitudinal Immune Response to 3 Doses of Messenger RNA Vaccine Against Coronavirus Disease

Autorzy: Thomas Lehrnbecher, Ulrich Sack, Carsten Speckmann, Andreas H Groll, Andreas Boldt, Benjamin Siebald, Simone Hettmer, Eva-Maria Demmerath, Judith Reemtsma, Barbara Schenk, Sandra Ciesek, Jan-Henning Klusmann, Christian Jassoy, Sebastian Hoehl
Opublikowane w: Clinical Infectious Diseases, Numer 76/3, 2023, Strona(/y) e510-e513, ISSN 1058-4838
Wydawca: University of Chicago Press
DOI: 10.1093/cid/ciac570

YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA

Autorzy: Andreas Kloetgen, Sujitha Duggimpudi, Konstantin Schuschel, Kebria Hezaveh, Daniel Picard, Heiner Schaal, Marc Remke, Jan-Henning Klusmann, Arndt Borkhardt, Alice C. McHardy, Jessica I. Hoell
Opublikowane w: International Journal of Molecular Sciences, Numer 21/12, 2020, Strona(/y) 4453, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21124453

Autolysosomal activation combined with lysosomal destabilization efficiently targets myeloid leukemia cells for cell death

Autorzy: Harshit Shah, Metodi Stankov, Diana Panayotova-Dimitrova, Amir Yazdi, Ramachandramouli Budida, Jan-Henning Klusmann, Georg M. N. Behrens
Opublikowane w: Frontiers in Oncology, Numer 13, 2023, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.999738

RNA-Binding Proteins in Acute Leukemias

Autorzy: Konstantin Schuschel, Matthias Helwig, Stefan Hüttelmaier, Dirk Heckl, Jan-Henning Klusmann, Jessica I Hoell
Opublikowane w: International Journal of Molecular Sciences, Numer 21/10, 2020, Strona(/y) 3409, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21103409

RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia

Autorzy: Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Di
Opublikowane w: Blood, Numer 141/10, 2023, Strona(/y) 1105-1118, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood.2022017619

Survival Following Relapse in Children with Acute Myeloid Leukemia: A Report from AML-BFM and COG

Autorzy: Mareike Rasche, Martin Zimmermann, Emma Steidel, Todd Alonzo, Richard Aplenc, Jean-Pierre Bourquin, Heidrun Boztug, Todd Cooper, Alan S. Gamis, Robert B. Gerbing, Iveta Janotova, Jan-Henning Klusmann, Thomas Lehrnbecher, Nora Mühlegger, Nils v. Neuhoff, Naghmeh Niktoreh, Lucie Sramkova, Jan Stary, Katharina Waack, Christiane Walter, Ursula Creutzig, Michael Dworzak,rd Andres Kolb, Dirk Reinhardt
Opublikowane w: Cancers (Basel), Numer 13/10, 2021, Strona(/y) 2336, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13102336

Survival Outcomes of Children with Relapsed or Refractory Myeloid Leukemia Associated with Down syndrome

Autorzy: Nikhil Raghuram, Kentaro Nakashima, Syaza Ab Rahman, Evangelia Antoniou, Torjus Skajaa, Pietro Merli, Anupam Verma, Karen R. Rabin, Catherine Aftandilian, Rishi Sury Kotecha, Daniel Ka Leung Cheuk, Kirsi Jahnukainen, Alexandra Kolenova, Walentyna Balwierz, Alice Norton, Maureen M O'Brien, Sonia Cellot, Ashley Chopek, Nira Arad-Cohen, Bianca F. Goemans, Marta Rojas-Vasquez, Hany Ariffin, Jack Bartr
Opublikowane w: Blood Advances, 2023, ISSN 2473-9537
Wydawca: American Society of Hematology
DOI: 10.1182/bloodadvances.2022009381

Molecular Mechanisms of the Genetic Predisposition to Acute Megakaryoblastic Leukemia in Infants With Down Syndrome

Autorzy: Juliane Grimm, Dirk Heckl, Jan-Henning Klusmann
Opublikowane w: Frontiers in Oncology, Numer 11, 2021, Strona(/y) 636633, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.636633

Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

Autorzy: Mareike Rasche, Martin Zimmermann, Lisa Borschel, Jean-Pierre Bourquin, Michael Dworzak, Thomas Klingebiel, Thomas Lehrnbecher, Ursula Creutzig, Jan-Henning Klusmann, Dirk Reinhardt
Opublikowane w: Leukemia, Numer 32/10, 2018, Strona(/y) 2167-2177, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-018-0071-7

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