Skip to main content
European Commission logo
polski polski
CORDIS - Wyniki badań wspieranych przez UE
CORDIS

Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy

Publikacje

Cardiac Microvascular Endothelial Cells in Pressure Overload-Induced Heart Disease.

Autorzy: S. Trenson, H. Hermans, S. Craps, P. Pokreisz, P. de Zeeuw, J. Van Wauwe, H. Gillijns, D. Veltman, F. Wei, E. Caluwe, R. Gijsbers, P. Baatsen, J.A. Staessen, B. Ghesquiere, P. CARMELIET, F. Rega, B. Meuris, B. Meyns, W. Oosterlinck, J. Duchenne, K. Goetschalckx, J.U. Voigt, M.C. Herregods, P. Herijgers, A. Luttun, and S. Janssens.
Opublikowane w: CIRCULATION-HEART FAILURE, Numer Volume 14 Numer 1, 2021, Strona(/y) 97-111, ISSN 1941-3297
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circheartfailure.120.006979

Hallmarks of Endothelial Cell Metabolism in Health and Disease.

Autorzy: Li, Xuri; Sun, Xiaodong; Carmeliet, Peter
Opublikowane w: Cell Metabolism, Numer 5, 2019, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2019.08.011

Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells.

Autorzy: A. Cuypers, L. A. Teuwen, V. L. Bridgeman, Lpmh de Rooij, G. Eelen, M. Dewerchin, A. R. Cantelmo, J. Kalucka, A. Bouche, S. Vinckier, A. Carton, A. Manderveld, P. B. Vermeulen, A. R. Reynolds & P. CARMELIET.
Opublikowane w: Star Protocols, 2022, ISSN 2666-1667
Wydawca: Cell Press
DOI: 10.1016/j.xpro.2022.101691

Metabolic Reprogramming in Tumor Endothelial Cells

Autorzy: M. Garcia-Caballero, L. Sokol, A. Cuypers & P. CARMELIET
Opublikowane w: International Journal of Molecular Sciences, Numer Vol23/Numer19, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911052

Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle

Autorzy: N.V. Conchinha, L. Sokol, L.A. Teuwen, K. Veys, S.J. Dumas, E. Meta, M. Garcia-Caballero, V. Geldhof, R. Chen, L. Treps, M. Borri, P. de Zeeuw, K.D. Falkenberg, C. Dubois, M. Parys, L. de Rooij, K. Rohlenova, J. Goveia, L. Schoonjans, M. Dewerchin, G. Eelen, X. Li, J. Kalucka & P. CARMELIET.
Opublikowane w: Star Protocols, Numer Vollume 2 Numer 3, 2021, Strona(/y) 100508, ISSN 2666-1667
Wydawca: Elsevier
DOI: 10.1016/j.xpro.2021.100508

Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver

Autorzy: L. Sokol, V. Geldhof, M. Garcia-Caballero, N.V. Conchinha, S.J. Dumas, E. Meta, L.A. Teuwen, K. Veys, R. Chen, L. Treps, M. Borri, P. de Zeeuw, K.D. Falkenberg, C. Dubois, M. Parys, L. de Rooij, J. Goveia, K. Rohlenova, L. Schoonjans, M. Dewerchin, G. Eelen, X. Li, J. Kalucka, & P. CARMELIET.
Opublikowane w: Star Protocols, Numer Volume 2 Numer 2, 2021, Strona(/y) 100489, ISSN 2666-1667
Wydawca: Elsevier
DOI: 10.1016/j.xpro.2021.100489

Tumor vessel co-option probed by single-cell analysis.

Autorzy: L.A. Teuwen, L. De Rooij, A. Cuypers, K. Rohlenova, S.J. Dumas, M. Garcia-Caballero, E. Meta, J. Amersfoort, F. Taverna, L.M. Becker, N. Veiga, A.R. Cantelmo, V. Geldhof, N.V. Conchinha, J. Kalucka, L. Treps, L.C. Conradi, S. Khan, T.K. Karakach, S. Soenen, S. Vinckier, L. Schoonjans, G. Eelen, S. Van Laere, M. Dewerchin, L. Dirix, M. Mazzone, Y. Luo, P. Vermeulen & P. CARMELIET
Opublikowane w: Cell Reports, Numer Volume 35 Numer 11, 2021, Strona(/y) ARTN 109253, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2021.109253

Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity

Autorzy: K. Veys, Z. Fan, M. Ghobrial, A. Bouche, M. Garcia-Caballero, K. Vriens, N. V. Conchinha, A. Seuwen, F. Schlegel, T. Gorski, M. Crabbe, P. Gilardoni, R. Ardicoglu, J. Schaffenrath, C. Casteels, G. De Smet, I. Smolders, K. Van Laere, E. D. Abel, S. M. Fendt, A. Schroeter, J. Kalucka, A. R. Cantelmo, T. Walchli, A. Keller, P. CARMELIET & K. De Bock
Opublikowane w: Circulation Research, 2020, ISSN 0009-7330
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.316463

Endothelial metabolism going single

Autorzy: A. Subramanian, L. M. Becker & P. CARMELIET
Opublikowane w: NATURE METABOLISM, Numer Volume 3 Numer 5, 2021, Strona(/y) 593-594, ISSN 2522-5812
Wydawca: NATURE RESEARCH
DOI: 10.1038/s42255-021-00399-3

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis

Autorzy: R. Tillie, J. De Bruijn, J. Perales-Paton, L. Temmerman, Y. Ghosheh, K. Van Kuijk, M.J. Gijbels, P. CARMELIET, K. Ley, J. Saez-Rodriguez & J.C. Sluimer
Opublikowane w: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, Numer Volume 9, 2021, Strona(/y) 11 pages ARTN 695684, ISSN 2296-634X
Wydawca: FRONTIERS MEDIA SA
DOI: 10.3389/fcell.2021.695684

Endothelial CFTR dysfunction and its involvement in the pathogenesis of pulmonary arterial hypertension

Autorzy: M. Declercq, L. Treps, S. Bousfia, P. CARMELIET & P. Witters
Opublikowane w: EUROPEAN RESPIRATORY JOURNAL, Numer Volume 58 Numer 2, 2021, Strona(/y) ARTN 2101645, ISSN 0903-1936
Wydawca: European Respiratory Society
DOI: 10.1183/13993003.01645-2021

Angiogenesis goes computational – The future way forward to discover new angiogenic targets?

Autorzy: A. Subramanian, P. Zakeri, M. Mousa, H. Alnaqbi, F. Y. Alshamsi, L. Bettoni, E. Damiani, H. Alsafar, Y. Saeys & P. CARMELIET
Opublikowane w: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, Numer Vol 20, 2022, Strona(/y) 5235-5255, ISSN 2001-0370
Wydawca: Elsevier
DOI: 10.1016/j.csbj.2022.09.019

Vasculogenesis in kidney organoids upon transplantation

Autorzy: M.S. Koning, S. J. Dumas, M. C. Avramut, R. I. Koning, E. Meta, et al, P. Carmeliet, et al
Opublikowane w: NPJ Regen Med, 2022, ISSN 2057-3995
Wydawca: Nature Portfolio
DOI: 10.1038/s41536-022-00237-4

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancer

Autorzy: an Nyen, T., M. Planque, L. van Wagensveld, J. A. G. Duarte, E. A. Zaal, A. Talebi, M. Rossi, P. R. Korner, et al, P. Carmeliet, et al
Opublikowane w: Nature Communications, Numer Vol 13, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-32272-6

Macrophage-derived glutamine boosts satellite cells and muscle regeneration.

Autorzy: M. Shang, F. Cappellesso, R. Amorim, J. Serneels, F. Virga, G. Eelen, S. Carobbio, M. Y. Rincon, P. Maechler, K. De Bock, P. C. Ho, M. Sandri, B. Ghesquiere, P. CARMELIET, M. Di Matteo, E. Berardi & M. Mazzone. Macrophage-derived glutamine boosts satellite cells and muscle regeneration.
Opublikowane w: Nature, 2020, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-020-2857-9

Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice

Autorzy: S. Stegen, C. S. Devignes, S. Torrekens, R. Van Looveren, P. CARMELIET & G. Carmeliet.
Opublikowane w: JOURNAL OF BONE AND MINERAL RESEARCH, Numer Volume 36 Numer 3, 2021, Strona(/y) 604-616, ISSN 0884-0431
Wydawca: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4219

Whole-Body Prolyl Hydroxylase Domain (PHD) 3 Deficiency Increased Plasma Lipids and Hematocrit Without Impacting Plaque Size in Low-Density Lipoprotein Receptor Knockout Mice.

Autorzy: J.A.F. Demandt, K. van Kuijk, T.L. Theelen, E. Marsch, S.P. Heffron, E.A. Fisher, P. CARMELIET, E.A.L. Biessen, and J.C. Sluimer.
Opublikowane w: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, Numer Volume 9, 2021, Strona(/y) 10 pages ARTN 664258, ISSN 2296-634X
Wydawca: FRONTIERS MEDIA SA
DOI: 10.3389/fcell.2021.664258

Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain

Autorzy: T. Walchli, J. Bisschop, A. Miettinen, A. Ulmann-Schuler, C. Hintermuller, E.P. Meyer, T. Krucker, R. Walchli, P.P. Monnier
Opublikowane w: NATURE PROTOCOLS, Numer Volume 16 Numer 10, 2021, Strona(/y) 4564, ISSN 1754-2189
Wydawca: Nature Publishing Group
DOI: 10.1038/s41596-021-00587-1

c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis

Autorzy: J. Leslie, M. G. Macia, S. Luli, J. C. Worrell, W. J. Reilly, H. L. Paish, A. Knox, B. S. Barksby, L. M. Gee, M. Y. W. Zaki, A. L. Collins, R. A. Burgoyne, R. Cameron, C. Bragg, X. Xu, G. W. Chung, C. D. A. Brown, A. D. Blanchard, C. B. Nanthakumar, M. Karsdal, S. M. Robinson, D. M. Manas, G. Sen, J. French, S. A. White, S. Murphy, M. Trost, J. L. Zakrzewski, U. Klein, R. F. Schwabe, I. Mederacke,
Opublikowane w: Nature Metabolism, 2020, ISSN 2522-5812
Wydawca: Nature
DOI: 10.1038/s42255-020-00306-2

Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Autorzy: F. Wang, P. Ding, X. Liang, et al, P. Carmeliet, et al
Opublikowane w: Nature communications, Numer Vol13,3620, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-34498-w

CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation

Autorzy: Fernandez-Garcia, J., F. Franco, S. Parik, P. Altea-Manzano, A. A. Pane, D. Broekaert, J. van Elsen, I. Vermeire, T. Schalley, M. Planque, T. van Brussel, R. Schepers, E. Modave, T. K. Karakach, P. CARMELIET, D. Lambrechts, P. C. Ho, and S. M. Fendt
Opublikowane w: Cell Reports, Numer Volume 41, Numer7, 2022, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2022.111639

Gas6 is dispensable for pubertal mammary gland development.

Autorzy: Mills, Kylie L.; Gomes, Angelica M.; Standlee, Courtney R.; Rojo, Michelle D.; Carmeliet, Peter; Lin, Zhen; Machado, Heather L.
Opublikowane w: PLoS ONE, Numer 1, 2018, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0208550

Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis.

Autorzy: S.J. Dumas, E. Meta, N.V. Conchinha, L. Sokol, R. Chen, M. Borri, L.A. Teuwen, K. Veys, M. Garcia-Caballero, V. Geldhof, L. Treps, P. de Zeeuw, K.D. Falkenberg, C. Dubois, M. Parys, L. de Rooij, K. Rohlenova, J. Goveia, L. Schoonjans, M. Dewerchin, G. Eelen, X. Li, J. Kalucka & P. CARMELIET
Opublikowane w: Star Protocols, Numer Volume 2 Numer 3, 2021, Strona(/y) 100523, ISSN 2666-1667
Wydawca: Elsevier
DOI: 10.1016/j.xpro.2021.100523

The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors

Autorzy: A. De Zutter, H. Crijns, N. Berghmans, M. Garcia-Caballero, L. Vanbrabant, N. Portner, V. Vanheule, P. Verscheure, M.M. Siddiquei, A.M. Abu El-Asrar, P. CARMELIET, P. Van Wielendaele, I. De Meester, J. Van Damme, P. Proost & S. Struyf.
Opublikowane w: Cancers, Numer volume 13 Numer 20, 2021, Strona(/y) ARTN 5090, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13205090

De novo serine synthesis regulates chondrocyte proliferation during bone development and repair

Autorzy: Stegen, S., S. Loopmans, I. Stockmans, K. Moermans, P. CARMELIET & G. Carmeliet
Opublikowane w: Bone Research, 2021, ISSN 2095-4700
Wydawca: Sichuan University Press
DOI: 10.1038/s41413-021-00185-7

Metabolic signatures of distinct endothelial phenotypes

Autorzy: S.J. Dumas, M. Garcia-Caballero & P. CARMELIET
Opublikowane w: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2020, ISSN 1043-2760
Wydawca: Elsevier BV
DOI: 10.1016/j.tem.2020.05.009

Endothelial cell metabolism:: an update anno 2017

Autorzy: LA Teuwen, N Draoui, C Dubois, P Carmeliet
Opublikowane w: Current Opinion in Hematology, 2017, ISSN 1065-6251
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/moh.0000000000000335

Deciphering Endothelial Heterogeneity in Health and Disease at Single Cell Resolution: Progress and Perspectives.

Autorzy: Becker, L. M., S. H. Chen, J. Rodor, Lpmh de Rooij, A. H. Baker, & P. CARMELIET.
Opublikowane w: CARDIOVASCULAR RESEARCH, 2021, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvac018

Prominin-1 controls stem cell activation by orchestrating ciliary dynamics

Autorzy: Singer, Donald; Thamm, Kristina; Zhuang, Heng; Karbanová, Jana; Gao, Yan; Walker, Jemma Victoria; Jin, Heng; Wu, Xiangnan; Coveney, Clarissa R; Marangoni, Pauline; Lu, Dongmei; Grayson, Portia Rebecca Clare; Gulsen, Tulay; Liu, Karen J; Ardu, Stefano; Wann, Angus KT; Luo, Shouqing; Zambon, Alexander C; Jetten, Anton M; Tredwin, Christopher; Klein, Ophir D; Attanasio, Massimo; Carmeliet, Peter; Hu
Opublikowane w: Embo Journal, Numer 1, 2019, ISSN 1460-2075
Wydawca: Wiley
DOI: 10.15252/embj.201899845

A Role for the Vascular Endothelium in Post-Acute COVID-19?

Autorzy: de Rooij, Lpmh, L. M. Becker & P. CARMELIET
Opublikowane w: CIRCULATION, Numer Volume 145 Numer 20, 2021, Strona(/y) 1503-1505, ISSN 0009-7322
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.122.059231

EndoDB: a database of endothelial cell transcriptomics data

Autorzy: Shawez Khan, Federico Taverna, Katerina Rohlenova, Lucas Treps, Vincent Geldhof, Laura de Rooij, Liliana Sokol, Andreas Pircher, Lena-Christin Conradi, Joanna Kalucka, Luc Schoonjans, Guy Eelen, Mieke Dewerchin, Tobias Karakach, Xuri Li, Jermaine Goveia, Peter Carmeliet
Opublikowane w: Nucleic Acids Research, Numer 47/D1, 2018, Strona(/y) D736-D744, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gky997

Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism

Autorzy: Nihed Draoui, Pauline de Zeeuw, Peter Carmeliet
Opublikowane w: Open Biology, Numer 7/12, 2017, Strona(/y) 170219, ISSN 2046-2441
Wydawca: Royal Society Publishing
DOI: 10.1098/rsob.170219

Endothelial Cell Metabolism

Autorzy: Guy Eelen, Pauline de Zeeuw, Lucas Treps, Ulrike Harjes, Brian W. Wong, Peter Carmeliet
Opublikowane w: Physiological Reviews, Numer 98/1, 2018, Strona(/y) 3-58, ISSN 0031-9333
Wydawca: American Physiological Society
DOI: 10.1152/physrev.00001.2017

COVID-19: the vasculature unleashed

Autorzy: Laure-Anne Teuwen, Vincent Geldhof, Alessandra Pasut, Peter Carmeliet
Opublikowane w: Nature Reviews Immunology, 2020, ISSN 1474-1733
Wydawca: Nature Publishing Group
DOI: 10.1038/s41577-020-0343-0

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

Autorzy: Joanna Kalucka, Laura Bierhansl, Nadine Vasconcelos Conchinha, Rindert Missiaen, Ilaria Elia, Ulrike Brüning, Samantha Scheinok, Lucas Treps, Anna Rita Cantelmo, Charlotte Dubois, Pauline de Zeeuw, Jermaine Goveia, Annalisa Zecchin, Federico Taverna, Francisco Morales-Rodriguez, Aleksandra Brajic, Lena-Christin Conradi, Sandra Schoors, Ulrike Harjes, Kim Vriens, Gregor-Alexander Pilz, Rongyuan Ch
Opublikowane w: Cell Metabolism, Numer 28/6, 2018, Strona(/y) 881-894.e13, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2018.07.016

Blockade of myeloid-derived suppressor cell expansion with all-trans retinoic acid increases the efficacy of anti-angiogenic therapy

Autorzy: Raimund Bauer, Florian Udonta, Mark Wroblewski, Isabel Ben-Batalla, Ines Miranda Santos, Federico Taverna, Meike Kuhlencord, Victoria Gensch, Sarina Päsler, Stefan Vinckier, Johanna M Brandner, Klaus Pantel, Carsten Bokemeyer, Thomas Vogl, Johannes Roth, Peter Carmeliet, Sonja Loges
Opublikowane w: Cancer Research, 2018, Strona(/y) canres.3415.2017, ISSN 0008-5472
Wydawca: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-17-3415

RAISEing VEGF-D’s importance as predictive biomarker for ramucirumab in metastatic colorectal cancer patients

Autorzy: P. Carmeliet, X. Li, L. Treps, L.-C. Conradi, S. Loges
Opublikowane w: Annals of Oncology, Numer 29/3, 2018, Strona(/y) 529-532, ISSN 0923-7534
Wydawca: Oxford University Press
DOI: 10.1093/annonc/mdy028

How glucose, glutamine and fatty acid metabolism shape blood and lymph vessel development

Autorzy: Laure-Anne Teuwen, Vincent Geldhof, Peter Carmeliet
Opublikowane w: Developmental Biology, Numer 447/1, 2019, Strona(/y) 90-102, ISSN 0012-1606
Wydawca: Academic Press
DOI: 10.1016/J.YDBIO.2017.12.001

The metabolic engine of endothelial cells

Autorzy: Kim D. Falkenberg, Katerina Rohlenova, Yonglun Luo, Peter Carmeliet
Opublikowane w: Nature Metabolism, Numer 1/10, 2019, Strona(/y) 937-946, ISSN 2522-5812
Wydawca: Springer Nature
DOI: 10.1038/s42255-019-0117-9

Metabolic Pathways Fueling the Endothelial Cell Drive

Autorzy: Xuri Li, Anil Kumar, Peter Carmeliet
Opublikowane w: Annual Review of Physiology, Numer 81/1, 2019, Strona(/y) 483-503, ISSN 0066-4278
Wydawca: Annual Reviews, Inc.
DOI: 10.1146/annurev-physiol-020518-114731

The role of endothelial cells in cystic fibrosis

Autorzy: M. Declercq, L. Treps, P. Carmeliet, P. Witters
Opublikowane w: Journal of Cystic Fibrosis, Numer 18/6, 2019, Strona(/y) 752-761, ISSN 1569-1993
Wydawca: Elsevier BV
DOI: 10.1016/j.jcf.2019.07.005

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Autorzy: Joanna Kalucka, Laura P.M.H. de Rooij, Jermaine Goveia, Katerina Rohlenova, Sébastien J. Dumas, Elda Meta, Nadine V. Conchinha, Federico Taverna, Laure-Anne Teuwen, Koen Veys, Melissa García-Caballero, Shawez Khan, Vincent Geldhof, Liliana Sokol, Rongyuan Chen, Lucas Treps, Mila Borri, Pauline de Zeeuw, Charlotte Dubois, Tobias K. Karakach, Kim D. Falkenberg, Magdalena Parys, Xiangke Yin, Stefan
Opublikowane w: Cell, Numer 180/4, 2020, Strona(/y) 764-779.e20, ISSN 0092-8674
Wydawca: Cell Press
DOI: 10.1016/j.cell.2020.01.015

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Autorzy: Jermaine Goveia, Katerina Rohlenova, Federico Taverna, Lucas Treps, Lena-Christin Conradi, Andreas Pircher, Vincent Geldhof, Laura P.M.H. de Rooij, Joanna Kalucka, Liliana Sokol, Melissa García-Caballero, Yingfeng Zheng, Junbin Qian, Laure-Anne Teuwen, Shawez Khan, Bram Boeckx, Els Wauters, Herbert Decaluwé, Paul De Leyn, Johan Vansteenkiste, Birgit Weynand, Xavier Sagaert, Erik Verbeken, Albert
Opublikowane w: Cancer Cell, Numer 37/1, 2020, Strona(/y) 21-36.e13, ISSN 1535-6108
Wydawca: Cell Press
DOI: 10.1016/j.ccell.2019.12.001

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

Autorzy: Katerina Rohlenova, Jermaine Goveia, Melissa García-Caballero, Abhishek Subramanian, Joanna Kalucka, Lucas Treps, Kim D. Falkenberg, Laura P.M.H. de Rooij, Yingfeng Zheng, Lin Lin, Liliana Sokol, Laure-Anne Teuwen, Vincent Geldhof, Federico Taverna, Andreas Pircher, Lena-Christin Conradi, Shawez Khan, Steve Stegen, Dena Panovska, Frederik De Smet, Frank J.T. Staal, Rene J. Mclaughlin, Stefan Vinc
Opublikowane w: Cell Metabolism, Numer 31/4, 2020, Strona(/y) 862-877.e14, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2020.03.009

BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization

Autorzy: Federico Taverna, Jermaine Goveia, Tobias K Karakach, Shawez Khan, Katerina Rohlenova, Lucas Treps, Abhishek Subramanian, Luc Schoonjans, Mieke Dewerchin, Guy Eelen, Peter Carmeliet
Opublikowane w: Nucleic Acids Research, Numer 48/W1, 2020, Strona(/y) W385-W394, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkaa332

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis

Autorzy: Guy Eelen, Charlotte Dubois, Anna Rita Cantelmo, Jermaine Goveia, Ulrike Brüning, Michael DeRan, Gopala Jarugumilli, Jos van Rijssel, Giorgio Saladino, Federico Comitani, Annalisa Zecchin, Susana Rocha, Rongyuan Chen, Hongling Huang, Saar Vandekeere, Joanna Kalucka, Christian Lange, Francisco Morales-Rodriguez, Bert Cruys, Lucas Treps, Leanne Ramer, Stefan Vinckier, Katleen Brepoels, Sabine Wyns,
Opublikowane w: Nature, Numer 561/7721, 2018, Strona(/y) 63-69, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-018-0466-7

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

Autorzy: Saar Vandekeere, Charlotte Dubois, Joanna Kalucka, Mark R. Sullivan, Melissa García-Caballero, Jermaine Goveia, Rongyuan Chen, Frances F. Diehl, Libat Bar-Lev, Joris Souffreau, Andreas Pircher, Saran Kumar, Stefan Vinckier, Yoshio Hirabayashi, Shigeki Furuya, Luc Schoonjans, Guy Eelen, Bart Ghesquière, Eli Keshet, Xuri Li, Matthew G. Vander Heiden, Mieke Dewerchin, Peter Carmeliet
Opublikowane w: Cell Metabolism, Numer 28/4, 2018, Strona(/y) 573-587.e13, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2018.06.009

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

Autorzy: Ulrike Bruning, Francisco Morales-Rodriguez, Joanna Kalucka, Jermaine Goveia, Federico Taverna, Karla C.S. Queiroz, Charlotte Dubois, Anna Rita Cantelmo, Rongyuan Chen, Stefan Loroch, Evy Timmerman, Vanessa Caixeta, Katarzyna Bloch, Lena-Christin Conradi, Lucas Treps, An Staes, Kris Gevaert, Andrew Tee, Mieke Dewerchin, Clay F. Semenkovich, Francis Impens, Birgit Schilling, Eric Verdin, Johannes V
Opublikowane w: Cell Metabolism, Numer 28/6, 2018, Strona(/y) 866-880.e15, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2018.07.019

Mitochondrial respiration supports autophagy to provide stress resistance during quiescence.

Autorzy: Magalhaes-Novais, S., J. Blecha, R. Naraine, J. Mikesova, P. Abaffy, A. Pecinova, M. Milosevic, R. Bohuslavova, J. Prochazka, S. Khan, E. Novotna, R. Sindelka, R. Machan, M. Dewerchin, E. Vlcak, J. Kalucka, S. Stemberkova Hubackova, A. Benda, J. Goveia, T. Mracek, C. Barinka, P. CARMELIET, J. Neuzil, K. Rohlenova & J. Rohlena.
Opublikowane w: AUTOPHAGY, 2021, ISSN 1554-8627
Wydawca: Landes Bioscience
DOI: 10.1080/15548627.2022.2038898

Tumor vessel co-option: The past & the future

Autorzy: A. Cuypers, A. K. Truong, L. M. Becker, P. Saavedra-Garcia, & P. CARMELIET
Opublikowane w: Frontiers in Oncology, Numer Vol 12, 2022, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.965277

Basic and Therapeutic Aspects of Angiogenesis Updated

Autorzy: Eelen, Guy; Treps, Lucas; Li, Xuri; Carmeliet, Peter
Opublikowane w: CIRCULATION RESEARCH, 2020, ISSN 0009-7330
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.120.316851

Endothelial cell plasticity at the single-cell level

Autorzy: A. Pasut, Lisa M. Becker, A. Cuypers & P. CARMELIET
Opublikowane w: Angiogenesis, Numer volume 24 Numer 2, 2021, Strona(/y) 311-326, ISSN 0969-6970
Wydawca: Kluwer Academic Publishers
DOI: 10.1007/s10456-021-09797-3

The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single cell resolution

Autorzy: Lpmh de Rooij, L. M. Becker, L. A. Teuwen, B. Boeckx, S. Jansen, S. Feys, S. Verleden, L. Liesenborghs, et al & P Carmeliet
Opublikowane w: Cardiovascular Research, Numer cva139, 2022, ISSN 1755-3245
Wydawca: Oxford Univ Press
DOI: 10.1093/cvr/cvac139

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

Autorzy: Sébastien J. Dumas, Elda Meta, Mila Borri, Jermaine Goveia, Katerina Rohlenova, Nadine V. Conchinha, Kim Falkenberg, Laure-Anne Teuwen, Laura de Rooij, Joanna Kalucka, Rongyuan Chen, Shawez Khan, Federico Taverna, Weisi Lu, Magdalena Parys, Carla De Legher, Stefan Vinckier, Tobias K. Karakach, Luc Schoonjans, Lin Lin, Lars Bolund, Mieke Dewerchin, Guy Eelen, Ton J. Rabelink, Xuri Li, Yonglun Luo
Opublikowane w: Journal of the american society of nephrology, Numer 31 (1), 2020, Strona(/y) 118-138, ISSN 1046-6673
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2019080832

Transcriptomic analysis of CFTR-impaired endothelial cells reveals a pro-inflammatory phenotype

Autorzy: M. Declercq, P. de Zeeuw, N. Vasconcelos Conchinha, V. Geldhof, A. S. Ramalho, M. Garcia-Caballero, K. Brepoels, M. Ensinck, M. S. Carlon, M. J. Bird, S. Vinckier, M. Proesmans, F. Vermeulen, L. Dupont, B. Ghesquiere, M. Dewerchin, P. CARMELIET, D. Cassiman, L. Treps, G. Eelen & P. Witters
Opublikowane w: EUROPEAN RESPIRATORY JOURNAL, Numer Volume 57 Numer 4, 2021, Strona(/y) ARTN 2000261, ISSN 0903-1936
Wydawca: European Respiratory Society
DOI: 10.1183/13993003.00261-2020

Phenotypic diversity and metabolic specialization of renal endothelial cells

Autorzy: S.J. Dumas, E. Meta, M. Borri, Y. Luo, X. Li, T.J. Rabelink & .P. CARMELIET.
Opublikowane w: NATURE REVIEWS NEPHROLOGY, Numer volume 17 Numer 7, 2021, ISSN 1759-5061
Wydawca: Nature Publishing Group
DOI: 10.1038/s41581-021-00411-9

Immunomodulation by endothelial cells – partnering up with the immune system?

Autorzy: J. Amersfoort, G. Eelen & P. CARMELIET
Opublikowane w: NATURE REVIEWS IMMUNOLOGY, 2021, ISSN 1474-1733
Wydawca: Nature Publishing Group
DOI: 10.1038/s41577-022-00694-4

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

Autorzy: M.D. Mana, A.M. Hussey, C.N. Tzouanas, S. Imada, Y. Barrera Millan, D. Bahceci, D.R. Saiz, A.T. Webb, C.A. Lewis, P. CARMELIET, M.M. Mihaylova, A.K. Shalek, and O.H. Yilmaz
Opublikowane w: CELL REPORTS, Numer Volume 35 Numer 10, 2021, Strona(/y) ARTN 109212, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2021.109212

Analysis of Endothelial Fatty Acid Metabolism Using Tracer Metabolomics.

Autorzy: Joanna Kalucka; Bart Ghesquière; Sarah-Maria Fendt; Peter Carmeliet
Opublikowane w: Methods in Molecular Biology, Numer 2, 2019, ISBN 978-1-4939-9235-5
Wydawca: HUMANA PRESS INC
DOI: 10.1007/978-1-4939-9236-2_16

Wyszukiwanie danych OpenAIRE...

Podczas wyszukiwania danych OpenAIRE wystąpił błąd

Brak wyników