Skip to main content
Przejdź do strony domowej Komisji Europejskiej (odnośnik otworzy się w nowym oknie)
polski pl
CORDIS - Wyniki badań wspieranych przez UE
CORDIS

Disentangling amygdala contributions to replay-mediated, hippocampal-dependent memory consolidation

Cel

In today’s societies, adequate rest takes second place to busy professional and personal schedules. It is known that lack of rest and sleep affects mental health, emotional regulation and daytime function. Such symptoms translate to increased healthcare costs and losses in workplace productivity. How emotional regulation processes interact with sleep and associated memory consolidation functions is not well understood. In addition to increasing basic understanding of brain function, addressing this knowledge gap can help shape therapeutic approaches for mental wellbeing and contribute to EU’s H2020 goals of smart, sustainable and growth.

VALENCE-REPLAY will provide a building block towards addressing this knowledge gap through experiments in behaving rodents. The questions to be addressed in this fellowship are: Are memory consolidation processes during sleep preferentially shaped according to the valence of prior experience? If this is so, how is this accomplished at a mechanistic level?

The work will use modern electrophysiology and optogenetic techniques to probe functional interactions of brain areas that mediate emotion (amygdala) and memory (hippocampus) and the role of these interactions in memory replay and consolidation during sleep. The project will also lead to fabrication of a new tool, parylene-based multisite neuronal recording probes that will permit tracking single neuron activity from the ventral hippocampus for adequate lengths of time to address the outlined research goals.

The fellowship will shed light on how emotions shape memory processes during sleep, but will also afford a committed and experienced researcher the opportunity to acquire advanced training at leading European neuroscience institutes while forming a strong scientific network with leaders in the field. Through VALENCE-REPLAY, Dr Perentos will develop into an independent researcher, able to lead his own research group and achieve high impact research in systems neuroscience.

Dziedzina nauki (EuroSciVoc)

Program(-y)

Temat(-y)

System finansowania

MSCA-IF-EF-ST - Standard EF

Wyświetl wszystkie projekty finansowane w ramach tego programu finansowania

Zaproszenie do składania wniosków

(odnośnik otworzy się w nowym oknie) H2020-MSCA-IF-2016

Wyświetl wszystkie projekty finansowane w ramach tego zaproszenia

Koordynator

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Wkład UE netto
€ 171 460,80
Adres
GESCHWISTER SCHOLL PLATZ 1
80539 Planegg
Niemcy
Region
Bayern Oberbayern München, Kreisfreie Stadt
Rodzaj działalności
Higher or Secondary Education Establishments
Linki
Koszt całkowity
€ 171 460,80