Super-resolution genomic mapping for the microbiome

Informacje na temat projektu

METAMAPPER

Identyfikator umowy o grant: 768826

DOI

10.3030/768826

Projekt został zamknięty

Data podpisania przez KE 28 Czerwca 2017

Data rozpoczęcia 1 Grudnia 2017

Data zakończenia 31 Maja 2019

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 149 875,00

Wkład UE

€ 149 875,00

Koordynowany przez

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium

Periodic Reporting for period 1 - METAMAPPER (Super-resolution genomic mapping for the microbiome)

Okres sprawozdawczy: 2017-12-01 do 2019-05-31

Podsumowanie kontekstu i ogólnych celów projektu

Within the metamapper project, a stable microscopy platform, optimized for super-resolved imaging of fluorescently labeled DNA has been successfully obtained. The microscope platform was designed and built to be compact, yet able of diffraction unlimited imaging of microbiome DNA. This device was complemented with a dedicated analysis pipeline for the rapid and efficient content analysis of microbial mixtures. Our experiments have shown that the system is stable over time and does not need regular realignment, another important requirement for high-throughput optical DNA mapping. Having reached proof-of-concept, the system is currently in benchmark studies, as we move towards commercialization.