Neural drivers of functional disconnectivity in brain disorders

Informacje na temat projektu

DisConn

Identyfikator umowy o grant: 802371

DOI

10.3030/802371

Projekt został zamknięty

Data podpisania przez KE 8 Listopada 2018

Data rozpoczęcia 1 Lutego 2019

Data zakończenia 31 Grudnia 2024

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 498 125,00

Wkład UE

€ 1 498 125,00

Koordynowany przez

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (22)

Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex

Autorzy: Federico Rocchi, Carola Canella, Shahryar Noei, Daniel Gutierrez-Barragan, Ludovico Coletta, Alberto Galbusera, Stefano Vassanelli, Massimo Pasqualetti, Giuliano Iurilli, Stefano Panzeri, Alessandro Gozzi
Opublikowane w: Nature Communications, Numer 13(1), 2022, Strona(/y) 1056, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1101/2020.08.05.237958

Microglia complement signaling promotes neuronal elimination and normal brain functional connectivity

Autorzy: Senthilkumar Deivasigamani, Mariya T Miteva, Silvia Natale, Daniel Gutierrez-Barragan, Bernadette Basilico, Silvia Di Angelantonio, Laetitia Weinhard, Dmitry Molotkov, Sukrita Deb, Constantin Pape, Giulia Bolasco, Alberto Galbusera, Hiroki Asari, Alessandro Gozzi, Davide Ragozzino, Cornelius T Gross
Opublikowane w: Cerebral Cortex, 2023, ISSN 1047-3211
Wydawca: Oxford University Press
DOI: 10.1093/cercor/bhad313

Evidence for increased parallel information transmission in human brain networks compared to macaques and male mice

Autorzy: Alessandra Griffa, Mathieu Mach, Julien Dedelley, Daniel Gutierrez-Barragan, Alessandro Gozzi, Gilles Allali, Joanes Grandjean, Dimitri Van De Ville, Enrico Amico
Opublikowane w: Nature Communications, Numer 14, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-43971-z

A consensus protocol for functional connectivity analysis in the rat brain

Autorzy: Joanes Grandjean, Gabriel Desrosiers-Gregoire, Cynthia Anckaerts, Diego Angeles-Valdez, Fadi Ayad, David A. Barrière, Ines Blockx, Aleksandra Bortel, Margaret Broadwater, Beatriz M. Cardoso, Marina Célestine, Jorge E. Chavez-Negrete, Sangcheon Choi, Emma Christiaen, Perrin Clavijo, Luis Colon-Perez, Samuel Cramer, Tolomeo Daniele, Elaine Dempsey, Yujian Diao, Arno Doelemeyer, David Dopfel, Lenka
Opublikowane w: Nature Neuroscience, Numer 26, 2025, Strona(/y) 673-681, ISSN 1097-6256
Wydawca: Nature Publishing Group
DOI: 10.1038/s41593-023-01286-8

Animal Functional Magnetic Resonance Imaging: Trends and Path Toward Standardization

Autorzy: Francesca Mandino, Domenic H. Cerri, Clement M. Garin, Milou Straathof, Geralda A. F. van Tilborg, M. Mallar Chakravarty, Marc Dhenain, Rick M. Dijkhuizen, Alessandro Gozzi, Andreas Hess, Shella D. Keilholz, Jason P. Lerch, Yen-Yu Ian Shih, Joanes Grandjean
Opublikowane w: Frontiers in Neuroinformatics, Numer 13, 2020, ISSN 1662-5196
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fninf.2019.00078

Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism

Autorzy: Bo-yong Park, Seok-Jun Hong, Sofie L. Valk, Casey Paquola, Oualid Benkarim, Richard A. I. Bethlehem, Adriana Di Martino, Michael P. Milham, Alessandro Gozzi, B. T. Thomas Yeo, Jonathan Smallwood, Boris C. Bernhardt
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-21732-0

Regional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network

Autorzy: Jennifer D.Whitesell, AdamLiska, Ludovico Coletta, Karla E.Hirokawa, Phillip Bohn, Ali Williford, Peter A. Groblewski, Nile Graddis, Leonard Kuan, Joseph E.Knox, Anh Ho, Wayne Wakeman, Philip R. Nicovich, Thuc Nghi Nguyen, Cindy TJ van Velthoven, Emma Garren, Olivia Fong, Maitham Naeemi, Alex M.Henry, Nick Dee, Kimberly A. Smith, Boaz Levi, David Feng, Lydia Ng, Bosiljka Tasic, Hongkui Zeng, Stefa
Opublikowane w: Neuron, Numer 109 (3), 2020, Strona(/y) 545-559, ISSN 0896-6273
Wydawca: Cell Press
DOI: 10.1016/j.neuron.2020.11.011

Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

Autorzy: Stavros Trakoshis, Pablo Martínez-Cañada, Federico Rocchi, Carola Canella, Wonsang You, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, John Suckling, Marija Markicevic, Valerio Zerbi, Simon Baron-Cohen, Alessandro Gozzi, Meng-Chuan Lai, Stefano Panzeri, Michael V Lombardo
Opublikowane w: eLife, Numer 9, 2020, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.55684

Macroscale coupling between structural and effective connectivity in the mouse brain

Autorzy: Danilo Benozzo, Giorgia Baron, Ludovico Coletta, Alessandro Chiuso, Alessandro Gozzi, Alessandra Bertoldo
Opublikowane w: Scientific Reports, Numer 14, 2024, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-024-51613-7

Evolutionarily conserved fMRI network dynamics in the mouse, macaque, and human brain

Autorzy: Daniel Gutierrez-Barragan, Julian S. B. Ramirez, Stefano Panzeri, Ting Xu, Alessandro Gozzi
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-52721-8

Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure

Autorzy: Urte Neniskyte, Ugne Kuliesiute, Auguste Vadisiute, Kristina Jevdokimenko, Ludovico Coletta, Senthilkumar Deivasigamani, Daina Pamedytyte, Neringa Daugelaviciene, Daiva Dabkeviciene, Emerald Perlas, Aditya Bali, Bernadette Basilico, Alessandro Gozzi, Davide Ragozzino, Cornelius T Gross
Opublikowane w: The EMBO Journal, Numer 42, 2023, ISSN 0261-4189
Wydawca: Nature Publishing Group
DOI: 10.15252/embj.2022111790

CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility

Autorzy: Patricia Nora Awad, Valerio Zerbi, Erin M. Johnson-Venkatesh, Francesca Damiani, Marco Pagani, Marija Markicevic, Sarah Nickles, Alessandro Gozzi, Hisashi Umemori, Michela Fagiolini
Opublikowane w: Molecular Psychiatry, Numer 29, 2024, Strona(/y) 1698-1709, ISSN 1359-4184
Wydawca: Nature Publishing Group
DOI: 10.1038/s41380-023-01962-y

Sex-biasing influence of autism-associated <i>Ube3a</i> gene overdosage at connectomic, behavioral, and transcriptomic levels

Autorzy: Caterina Montani, Luigi Balasco, Marco Pagani, Filomena Grazia Alvino, Noemi Barsotti, A. Elizabeth de Guzman, Alberto Galbusera, Alessia de Felice, Thomas K. Nickl-Jockschat, Sara Migliarini, Simona Casarosa, Pierre Lau, Lorenzo Mattioni, Massimo Pasqualetti, Giovanni Provenzano, Yuri Bozzi, Michael V. Lombardo, Alessandro Gozzi
Opublikowane w: Science Advances, Numer 10, 2024, ISSN 2375-2548
Wydawca: Science Pubslishing
DOI: 10.1126/sciadv.adg1421

Network structure of the mouse brain connectome with voxel resolution

Autorzy: Ludovico Coletta, Marco Pagani, Jennifer D. Whitesell, Julie A. Harris, Boris Bernhardt, Alessandro Gozzi
Opublikowane w: Science Advances, Numer 6/51, 2020, Strona(/y) eabb7187, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abb7187

Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes.

Autorzy: Valerio Zerbi; Marco Pagani; Marija Markicevic; Michela Matteoli; Davide Pozzi; Michela Fagiolini; Yuri Bozzi; Alberto Galbusera; Maria Luisa Scattoni; Giovanni Provenzano; Abhishek Banerjee; Abhishek Banerjee; Fritjof Helmchen; M A Basson; J. Ellegood; Jason P. Lerch; Jason P. Lerch; Markus Rudin; Alessandro Gozzi; Nicole Wenderoth
Opublikowane w: Molecular Psychiatry, Numer 1, 2022, ISSN 1359-4184
Wydawca: Nature Publishing Group
DOI: 10.1038/s41380-021-01245-4

Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism

Autorzy: Tommaso Nuzzo, Masae Sekine, Daniela Punzo, Mattia Miroballo, Masumi Katane, Yasuaki Saitoh, Alberto Galbusera, Massimo Pasqualetti, Francesco Errico, Alessandro Gozzi, Jean-Pierre Mothet, Hiroshi Homma, Alessandro Usiello
Opublikowane w: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Numer 1868/12, 2020, Strona(/y) 140531, ISSN 1570-9639
Wydawca: Elsevier BV
DOI: 10.1016/j.bbapap.2020.140531

Somatosensory processing deficits and altered cortico-hippocampal connectivity in Shank3b-/- mice

Autorzy: Luigi Balasco; Marco Pagani; Luca Pangrazzi; Evgenia Schlosman; Lorenzo Mattioni; Alberto Galbusera; Giovanni Provenzano; Alessandro Gozzi; Yuri Bozzi
Opublikowane w: Cerebral Cortex, Numer 1, 2022, ISSN 1047-3211
Wydawca: Oxford University Press
DOI: 10.1093/cercor/bhab399

Infraslow State Fluctuations Govern Spontaneous fMRI Network Dynamics

Autorzy: Daniel Gutierrez-Barragan, M. Albert Basson, Stefano Panzeri, Alessandro Gozzi
Opublikowane w: Current Biology, Numer 29/14, 2019, Strona(/y) 2295-2306.e5, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2019.06.017

Mapping and comparing fMRI connectivity networks across species

Autorzy: Marco Pagani, Daniel Gutierrez‐Barragan, A. Elizabeth de Guzman, Ting Xu, Alessandro Gozzi
Opublikowane w: Communications Biology, Numer 6, 2023, ISSN 2399-3642
Wydawca: Nature Publishing Group
DOI: 10.1038/s42003-023-05629-w

mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity

Autorzy: Pagani M, Barsotti N, Bertero A, Trakoshis S, Ulysse L, Locarno A, Miseviciute I, De Felice A, Canella C, Supekar K, Galbusera A, Menon V, Tonini R, Deco G, Lombardo MV, Pasqualetti M, Gozzi A
Opublikowane w: Nature Communications, Numer 12, 2021, Strona(/y) 6804, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-26131-z

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

Autorzy: Joanes Grandjean, Carola Canella, Cynthia Anckaerts, Gülebru Ayrancı, Salma Bougacha, Thomas Bienert, David Buehlmann, Ludovico Coletta, Daniel Gallino, Natalia Gass, Clément M. Garin, Nachiket Abhay Nadkarni, Neele S. Hübner, Meltem Karatas, Yuji Komaki, Silke Kreitz, Francesca Mandino, Anna E. Mechling, Chika Sato, Katja Sauer, Disha Shah, Sandra Strobelt, Norio Takata, Isabel Wank, Tong Wu,
Opublikowane w: NeuroImage, Numer 205, 2020, Strona(/y) 116278, ISSN 1053-8119
Wydawca: Academic Press
DOI: 10.1016/j.neuroimage.2019.116278

Unique spatiotemporal fMRI dynamics in the awake mouse brain

Autorzy: Daniel Gutierrez-Barragan, Neha Atulkumar Singh, Filomena Alvino, Ludovico Coletta, Federico Rocchi, Elizabeth De Guzman, Alberto Galbusera, Stefano Panzeri, Mauro Uboldi, Alessandro Gozzi
Opublikowane w: Current Biology, Numer 32(3), 2022, Strona(/y) 631-644.e6, ISSN 0960-9822
Wydawca: Cell Press
DOI: 10.1016/j.cub.2021.12.015