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spontaneous Evolution and Clonal heterOgeneity in MoNoclonal Gammopathies: from mechanisms of progression to clinical management

Publikacje

Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities

Autorzy: Bénedith Oben, Guy Froyen, Kylee H. Maclachlan, Daniel Leongamornlert, Federico Abascal, Binbin Zheng-Lin, Venkata Yellapantula, Andriy Derkach, Ellen Geerdens, Benjamin T. Diamond, Ingrid Arijs, Brigitte Maes, Kimberly Vanhees, Malin Hultcrantz, Elisabet E. Manasanch, Dickran Kazandjian, Alexander Lesokhin, Ahmet Dogan, Yanming Zhang, Aneta Mikulasova, Brian Walker, Gareth Morgan, Peter J. Campb
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-22140-0

Application of Next-Generation Sequencing for the Genomic Characterization of Patients with Smoldering Myeloma

Autorzy: Martina Manzoni, Valentina Marchica, Paola Storti, Bachisio Ziccheddu, Gabriella Sammarelli, Giannalisa Todaro, Francesca Pelizzoni, Simone Salerio, Laura Notarfranchi, Alessandra Pompa, Luca Baldini, Niccolò Bolli, Antonino Neri, Nicola Giuliani, Marta Lionetti
Opublikowane w: Cancers, Numer 12/5, 2020, Strona(/y) 1332, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12051332

Next-Generation Sequencing for Clinical Management of Multiple Myeloma: Ready for Prime Time?

Autorzy: Niccolo Bolli, Elisa Genuardi, Bachisio Ziccheddu, Marina Martello, Stefania Oliva, Carolina Terragna
Opublikowane w: Frontiers in Oncology, Numer 10, 2020, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2020.00189

Limits and Applications of Genomic Analysis of Circulating Tumor DNA as a Liquid Biopsy in Asymptomatic Forms of Multiple Myeloma

Autorzy: Martina Manzoni, Alessandra Pompa, Sonia Fabris, Francesca Pelizzoni, Gabriella Ciceri, Manuela Seia, Bachisio Ziccheddu, Niccolò Bolli, Paolo Corradini, Luca Baldini, Antonino Neri, Marta Lionetti
Opublikowane w: HemaSphere, Numer 4/4, 2020, Strona(/y) e402, ISSN 2572-9241
Wydawca: Wolters Kluwer Health, Inc. on behalf of the European Hematology Association
DOI: 10.1097/hs9.0000000000000402

Transcriptomic Analysis in Multiple Myeloma and Primary Plasma Cell Leukemia with t(11;14) Reveals Different Expression Patterns with Biological Implications in Venetoclax Sensitivity

Autorzy: Katia Todoerti, Elisa Taiana, Noemi Puccio, Vanessa Favasuli, Marta Lionetti, Ilaria Silvestris, Massimo Gentile, Pellegrino Musto, Fortunato Morabito, Umberto Gianelli, Niccolò Bolli, Luca Baldini, Antonino Neri, Domenica Ronchetti
Opublikowane w: Cancers, Numer 13/19, 2021, Strona(/y) 4898, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13194898

Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma

Autorzy: Yanira Ruiz-Heredia, Alejandra Ortiz-Ruiz, Mehmet K. Samur, Vanesa Garrido, Laura Rufian, Ricardo Sanchez, Pedro Aguilar-Garrido, Santiago Barrio, Miguel A. Martín, Niccolò Bolli, Yu-Tzu Tai, Raphaël Szalat, Mariateresa Fulciniti, Nikhil Munshi, Joaquín Martínez-López, María Linares, Miguel Gallardo
Opublikowane w: Cancers, Numer 13/13, 2021, Strona(/y) 3189, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13133189

Timing the initiation of multiple myeloma

Autorzy: Even H. Rustad, Venkata Yellapantula, Daniel Leongamornlert, Niccolò Bolli, Guy Ledergor, Ferran Nadeu, Nicos Angelopoulos, Kevin J. Dawson, Thomas J. Mitchell, Robert J. Osborne, Bachisio Ziccheddu, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, Philippe Moreau, Elli Papaemmanuil, Ludmil B. Alexandrov, Xose S. Puente, Elias Campo, Reiner Siebert, Herve Avet-Loiseau
Opublikowane w: Nature Communications, Numer 11/1, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-020-15740-9

DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome

Autorzy: Katia Todoerti, Domenica Ronchetti, Vanessa Favasuli, Francesco Maura, Fortunato Morabito, Niccolò Bolli, Elisa Taiana, Antonino Neri
Opublikowane w: Haematologica, 2020, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2021.278342

Genomics of Smoldering Multiple Myeloma: Time for Clinical Translation of Findings?

Autorzy: Marta Lionetti, Matteo C. Da Vià, Francesco Albano, Antonino Neri, Niccolò Bolli, Pellegrino Musto
Opublikowane w: Cancers, Numer 13/13, 2021, Strona(/y) 3319, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13133319

Integrative analysis of the genomic and transcriptomic landscape of double-refractory multiple myeloma

Autorzy: Bachisio Ziccheddu, Giulia Biancon, Filippo Bagnoli, Chiara De Philippis, Francesco Maura, Even H. Rustad, Matteo Dugo, Andrea Devecchi, Loris De Cecco, Marialuisa Sensi, Carolina Terragna, Marina Martello, Tina Bagratuni, Efstathios Kastritis, Meletios A. Dimopoulos, Michele Cavo, Cristiana Carniti, Vittorio Montefusco, Paolo Corradini, Niccolo Bolli
Opublikowane w: Blood Advances, Numer 4/5, 2020, Strona(/y) 830-844, ISSN 2473-9529
Wydawca: American Society of Hematology
DOI: 10.1182/bloodadvances.2019000779

Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma

Autorzy: Kylee H. Maclachlan, Even H. Rustad, Andriy Derkach, Binbin Zheng-Lin, Venkata Yellapantula, Benjamin Diamond, Malin Hultcrantz, Bachisio Ziccheddu, Eileen M. Boyle, Patrick Blaney, Niccolò Bolli, Yanming Zhang, Ahmet Dogan, Alexander M. Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-25469-8

mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies

Autorzy: Even H. Rustad, Ferran Nadeu, Nicos Angelopoulos, Bachisio Ziccheddu, Niccolò Bolli, Xose S. Puente, Elias Campo, Ola Landgren, Francesco Maura
Opublikowane w: Communications Biology, Numer 4/1, 2021, ISSN 2399-3642
Wydawca: Nature Publishing Group
DOI: 10.1038/s42003-021-01938-0

What Is New in the Treatment of Smoldering Multiple Myeloma?

Autorzy: Niccolo’ Bolli, Nicola Sgherza, Paola Curci, Rita Rizzi, Vanda Strafella, Mario Delia, Vito Pier Gagliardi, Antonino Neri, Luca Baldini, Francesco Albano, Pellegrino Musto
Opublikowane w: Journal of Clinical Medicine, Numer 10/3, 2021, Strona(/y) 421, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10030421

A practical guide for mutational signature analysis in hematological malignancies

Autorzy: Francesco Maura, Andrea Degasperi, Ferran Nadeu, Daniel Leongamornlert, Helen Davies, Luiza Moore, Romina Royo, Bachisio Ziccheddu, Xose S. Puente, Herve Avet-Loiseau, Peter J. Campbell, Serena Nik-Zainal, Elias Campo, Nikhil Munshi, Niccolò Bolli
Opublikowane w: Nature Communications, Numer 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-11037-8

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Autorzy: Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J. Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J. Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Glodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth
Opublikowane w: Nature Communications, Numer 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-11680-1

Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma

Autorzy: Bachisio Ziccheddu, Matteo C. Da Vià, Marta Lionetti, Akihiro Maeda, Silvia Morlupi, Matteo Dugo, Katia Todoerti, Stefania Oliva, Mattia D'Agostino, Paolo Corradini, Ola Landgren, Francesco Iorio, Loredana Pettine, Alessandra Pompa, Martina Manzoni, Luca Baldini, Antonino Neri, Francesco Maura, Niccolò Bolli
Opublikowane w: Clinical Cancer Research, 2021, ISSN 1078-0432
Wydawca: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-20-4366

A Journey Through Myeloma Evolution: From the Normal Plasma Cell to Disease Complexity

Autorzy: Matteo C. Da Vià, Bachisio Ziccheddu, Akihiro Maeda, Filippo Bagnoli, Giulia Perrone, Niccolò Bolli
Opublikowane w: HemaSphere, Numer 4/6, 2020, Strona(/y) e502, ISSN 2572-9241
Wydawca: Wolters Kluwer Health, Inc. on behalf of the European Hematology Association
DOI: 10.1097/hs9.0000000000000502

mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies.

Autorzy: Even H Rustad; Even H Rustad; Ferran Nadeu; Nicos Angelopoulos; Bachisio Ziccheddu; Bachisio Ziccheddu; Niccolo Bolli; Niccolo Bolli; Xose S. Puente; Elias Campo; Ola Landgren; Ola Landgren; Francesco Maura; Francesco Maura
Opublikowane w: 12, Numer 1, 2021, ISSN 2399-3642
Wydawca: Nature Publishing Group
DOI: 10.1038/s42003-021-01938-0

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