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Controlled Organoids transplantation as enabler for regenerative medicine translation


Project webpage

Description of the ORGANTRANS webpage that will be prepared in the first months of the project

Dissemination and communication strategy

The definition of the dissemination and communication strategy and tools to be used during the life of the project All possible dissemination routes for the obtained results will be identified and used during the whole course of the project

Sensor for the monitoring of dissolved oxygen

Report describing the performances of the oxygen sensing system composed of sensor and reader The working range will be 1 to 21 O2 with an accuracy of 05 O2 and precision of 05

Protocol for the large-scale production of liver organoids

Publication of an optimised SOP for largescale expansion of organoids cultured in spinning bioreactors

Six established and fully characterized individual hepatic organoid lines

Characterisation of the organoid lines with respect to stem cell characteristics and differentiation potential will be published

Upscaling from research to medical Sphericalplate 5D

Upscaling takes place by changing the Sphericalplate 5D research plate to the Sphericalplate 5D medical platform and assures the biological integrity of the cultivated organoids


Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells

Autorzy: Kerstin Schneeberger, Natalia Sánchez‐Romero, Shicheng Ye, Frank G. Steenbeek, Loes A. Oosterhoff, Iris Pla Palacin, Chen Chen, Monique E. Wolferen, Gilles Tienderen, Ruby Lieshout, Haaike Colemonts‐Vroninks, Imre Schene, Ruurdtje Hoekstra, Monique M.A. Verstegen, Luc J.W. Laan, Louis C. Penning, Sabine A. Fuchs, Hans Clevers, Joery De Kock, Pedro M. Baptista, Bart Spee
Opublikowane w: Hepatology, Numer 72/1, 2020, Strona(/y) 257-270, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.31037

Bicyclic RGD peptides enhance nerve growth in synthetic PEG-based Anisogels

Autorzy: Sitara Vedaraman, Dominik Bernhagen, Tamas Haraszti, Christopher Licht, Arturo Castro Nava, Abdolrahman Omidinia Anarkoli, Peter Timmerman, Laura De Laporte
Opublikowane w: Biomaterials Science, Numer 9/12, 2021, Strona(/y) 4329-4342, ISSN 2047-4830
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d0bm02051f

Digitally Fabricated and Naturally Augmented In Vitro Tissues

Autorzy: Daniela F. Duarte Campos, Laura De Laporte
Opublikowane w: Advanced Healthcare Materials, Numer 10/2, 2021, Strona(/y) 2001253, ISSN 2192-2640
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202001253

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

Autorzy: Ary Marsee, Floris J.M. Roos, Monique M.A. Verstegen, Helmuth Gehart, Eelco de Koning, Frédéric Lemaigre, Stuart J. Forbes, Weng Chuan Peng, Meritxell Huch, Takanori Takebe, Ludovic Vallier, Hans Clevers, Luc J.W. van der Laan, Bart Spee, Ary Marsee, Floris Roos, Monique Verstegen, Hans Clevers, Ludovic Vallier, Takanori Takebe, Meritxell Huch, Weng Chuan Peng, Stuart Forbes, Frédéric Lemaigre
Opublikowane w: Cell Stem Cell, Numer 28/5, 2021, Strona(/y) 816-832, ISSN 1934-5909
Wydawca: Cell Press
DOI: 10.1016/j.stem.2021.04.005

Report on the Third Regenerative medicine workshop

Autorzy: Pacheco Blanco, Mariana; Horokhovatskyi, Yevhen; Saar, Kristin; Aldag, Kristin
Opublikowane w:, Numer 2, 2023
DOI: 10.5281/zenodo.8054785

Report on the Second Regenerative medicine workshop

Autorzy: Mariana Pacheco Blanco; Yevhen Horokhovatskyi; Kristin Aldag; Kristin Saar
Opublikowane w:, Numer 6, 2023
DOI: 10.5281/zenodo.7947747

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