CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.
I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .
Risultati finali
Protocols will be developed for the collection, pre-processing and storage of blood, urine, exhaled breath and exhaled breath condensate samples to be incorporated in WP6 and 7 study protocols.
Report on the establishment of the EPHOR mega cohort (si apre in una nuova finestra)The EPHOR mega cohort will be created including cohorts with data on occupational histories Occupations will be coded including using automated free text mining developed in WP4 crosswalks between different coding systems will be developed and used to harmonize data across different occupational coding systems and versions together with WP4 and the newly developed EuroJEM WP2 will be applied to occupational histories over the lifecourse of included participants A framework for decentralized largescale pooling of data for epidemiological analyses will be implemented with WP4
Report on dynamic coding for more meaningful categories for exposure assessment (si apre in una nuova finestra)Improved coding systems will be developed and used in by WP2 for more flexible coding that allows for different coding structures depending on the risk factor.
Inventory of European cohorts with extensive information on occupational exposures (si apre in una nuova finestra)Extension and refinement of a searchable web-based database inventory of occupational cohorts based on the ongoing COST Action OMEGA-NET.
Protocol for feasibility study (si apre in una nuova finestra)Protocol for the feasibility study, that will be conducted in at least two countries with at least 12 participants, to test the exposure protocol including the wearable sensor system in the field. The exposure protocol will ultimately be applied in the case studies.
Report on the external exposome protocol development for the case studies (si apre in una nuova finestra)Development of a full external exposome protocol for in the case studies that will bring together the protocols on the wearable sensor system and passive sampling A protocol for field implementation informed consent forms data collection QAQC data management and data analysis will be developed with the case studies The protocol will also encompass a digital questionnaire on working time sleep specific chemical and physical exposures diet lifestyle workplace organisation psychosocial factors and jobrecords
Report on protocol for including new data in EuroJEM (si apre in una nuova finestra)To ensure that the dynamic EuroJEM includes the latest available information of highest quality possible a protocol will be developed for including new data into EuroJEM The protocol will include methods for searching and collecting new data from literature assisted by text mining WP4 exposure databases eg ECHA REACH database reports and Bayesian decision criteria to determine if and how to revise exposure estimates in the JEM This task will also investigate the use of optimized and dynamic coding systems
Report on tutorial on the use of hierarchical models in working-life exposome research (si apre in una nuova finestra)Hierarchical regression methods will be further developed and applied to the EPHOR mega cohort WP5 to identify new exposuredisease associations in the agnostic analyses and use the outcomes within WP2 to evaluate and improve EuroJEM
Report on harmonizing existing JEMs (si apre in una nuova finestra)Occupational codes will be harmonized Inconsistencies and gaps between different JEMs will be resolved by expert judgement leaving the possibility to keep betweencountry differences when factually motivated Imputation will be applied to cover missing values occupationscountries resulting in a first version of EuroJEM
Report on tutorial for the application of a suite of ‘multiple exposure methods' (si apre in una nuova finestra)Methods capable of handling multiple exposures in exposureresponse analyses will be developed This includes the conventional approach of analysing all exposureresponse associations in parallel while adjusting for multiple comparisons and novel methods based on machine learning approaches that account for the correlations between exposures
Report on inventory of ETR models relevant for EPHOR (si apre in una nuova finestra)An inventory will be compiled of all Compartmental multistate models twostage clonal expansion models and exposure rate models for ETR analyses that have been published to date This inventory will document what the underlying assumptions of these models are what inference they provide and to what extent they overlap
Protocol of study on working life exposome and respiratory health (si apre in una nuova finestra)A protocol will be developed for new data collection on respiratory health and working life exposome in 12 study centres from 7 European countries (Spain, France, Sweden, Norway, Estonia, Iceland, Denmark) and Australia.
Report on collection and defining JEMs (si apre in una nuova finestra)For each JEM information will be collected on coding systems of occupation and industry timeperiods covered and time intervals exposure indices and data sources For each exposure definitions of exposednonexposed will be suggested based on an agreed European background level of exposure and the unit of exposure to be used
Report on automated job coding (si apre in una nuova finestra)Improved methods for automated coding of free text fields in occupational histories into job coding will be developed based on artificial intelligence AI mimicking human experts for coding of occupational histories to be used in WP5
Report on methods and results passive sampling method (si apre in una nuova finestra)Protocol development for applying and analyzing passive sampling wristbands for chemical analyses and passive dust collection for biological analyses. Analyses and reporting on passive samples collected in the case studies.
Report on development of new and more specific JEMs (si apre in una nuova finestra)New partsdimensions for the EuroJEM will be developed to cover 1 selected exposures which for the same occupational code vary largely by industry eg mechanic maintenance or assembly worker or by gender eg job control physical work load 2 key emerging risks eg threats and violence at work 3 new concepts eg societal status of the work 4 employment conditions eg nonstandard temporarily in another country precarious and 5 key nonoccupational exposures lifestyle socioeconomic conditions will be addressed when countryspecific data are available by occupational code
Webbased toolbox version 10 including an interactive visualization tool several protocols for external and internal exposome assessment searchable databases of JEMs and populations
Pubblicazioni
Autori:
William Mueller, Alice Smith, Eelco Kuijpers, , Anjoeka Pronk, , Miranda Loh
Pubblicato in:
Annals of Work Exposures and Health, Numero xx, 2024, Pagina/e 1-7, ISSN 2398-7308
Editore:
Oxford Acedemic
DOI:
10.1093/annweh/wxae057
Autori:
Eline Verscheure a, Rob Stierum b, Vivi Schlünssen c, Anne Mette Lund Würtz c, Dorian Vanneste a, Manolis Kogevinas d, Barbara N. Harding d, Karin Broberg e f, Shan Zienolddiny-Narui g, Johanna Samulin Erdem g, Mrinal K. Das g, Konstantinos C. Makris h, Corina Konstantinou h, Xanthi Andrianou h, Susan Dekkers b, Lorna Morris i 1, Anjoeka Pronk b, Lode Godderis a j 2, Manosij Ghosh a 2, of EPHOR
Pubblicato in:
Enviromental research, Numero 238; 1, 2023, Pagina/e 117001, ISSN 0013-9351
Editore:
Academic Press
DOI:
10.1016/j.envres.2023.117001
Autori:
Annika M. Schoene; Ioannis Basinas; Martie van Tongeren; Sophia Ananiadou
Pubblicato in:
International Journal of Environmental Research and Public Health, Numero 19 (14), 2022, Pagina/e 1-14, ISSN 1660-4601
Editore:
MDPI (Multidisciplinary Digital Publishing Institute)
DOI:
10.3390/ijerph19148544
Autori:
Rachel Louise Hasting, Karen Marieke Oude Hengel, Taina Leinonen, Ute Bültmann, Ingrid Sivesind Mehlum, Alex Burdorf, Michelle C Turner, Laura Salonen, Damien M McElvenny, Svetlana Solovieva
Pubblicato in:
BMC Public Health, Numero 25, 2025, ISSN 1471-2458
Editore:
BioMed Central
DOI:
10.1186/s12889-025-23487-5
Autori:
Else T Würtz, Kirsten Pugdahl, Morten Fenger-Grøn, Ina A Berglind, Mark P C Cherrie, Anna Dahlman-Höglund, Kasper Grandahl, Jelena Macan, Alberto Modenese, Hilde Notø, Svetlana Solovieva, Kurt Straif, Marc Wittlich, Sven Connemann, Timo Heepenstrick, Peter A Philipsen, Stephan Westerhausen, Calvin B Ge, Johnni Hansen, Cheryl E Peters, Ingrid Sivesind Mehlum, Vivi Schlünssen, Henrik A Kolstad
Pubblicato in:
Annals of Work Exposures and Health, Numero 69, 2025, Pagina/e 415-428, ISSN 2398-7308
Editore:
Oxford University Press (OUP)
DOI:
10.1093/annweh/wxaf011
Autori:
Svetlana Solovieva, Astrid de Wind, Karina Undem, Christian Dudel, Ingrid S. Mehlum, Swenne G. van den Heuvel, Suzan J. W. Robroek & Taina Leinonen
Pubblicato in:
BMC Public Health, Numero 24, 2024, Pagina/e 735, ISSN 1471-2458
Editore:
BioMed Central
DOI:
10.1186/s12889-024-18229-y
Autori:
Tianlin Zhang, Annika M. Schoene, Shaoxiong Ji, Sophia Ananiadou
Pubblicato in:
npj Digital Medicine, Numero 5, 2024, ISSN 2398-6352
Editore:
Springer Science and Business Media LLC
DOI:
10.1038/s41746-022-00589-7
Autori:
Hartikainen, E., Solovieva, S., Viikari-Juntura, E., & Leinonen, T.
Pubblicato in:
Scandinavian Journal of Work, Environment & Health, Numero 2023;49(1):23-32, 2023, Pagina/e 23-32, ISSN 0355-3140
Editore:
Nordic Association of Occupational Safety and Health (NOROSH)
DOI:
10.5271/sjweh.4054
Autori:
Johanna Samulin Erdem, Mrinal K. Das, Evi De Ryck, Øivind Skare, Jenny-Anne S. Lie, Merete Bugge, Barbara Harding, Ingrid L. Jorgensen, Ingrid Sivesind Mehlum, Manolis Kogevinas, Karl-Christian Nordby, Shan Zienolddiny-Narui
Pubblicato in:
Environmental Research, Numero 276, 2025, Pagina/e 121503, ISSN 0013-9351
Editore:
Academic Press
DOI:
10.1016/j.envres.2025.121503
Autori:
Evi De Ryck; Manosij Ghosh; Tim S. Nawrot; Brigitte Reimann; Gudrun Koppen; Els Verachtert; Roland Devlieger; Lode Godderis; Sara Pauwels
Pubblicato in:
Environmental Pollution, Numero 346 (1), 2024, Pagina/e 1, ISSN 0269-7491
Editore:
Pergamon Press Ltd.
DOI:
10.1016/j.envpol.2024.123465
Autori:
Pronk, Anjoeka; Loh, Miranda; Kuijpers, Eelco; Albin, Maria; Selander, Jenny; Godderis, Lode; Ghosh, Manosij; Vermeulen, Roel; Peters, Susan; Mehlum, Ingrid Sivesind; Turner, Michelle C.; Schlünssen, Vivi; Goldberg, Marcel; Kogevinas, Manolis; Harding, Barbara N.; Solovieva, Svetlana; Garani-Papadatos, Tina; van Tongeren, Martie; Stierum, Rob
Pubblicato in:
Environmental Epidemiology, Numero 2, 2022, ISSN 2474-7882
Editore:
Wolters Kluwer Health
DOI:
10.1097/ee9.0000000000000185
Autori:
López-Cervantes, J. P., Lønnebotn, M., Jogi, N. O., Calciano, L., Kuiper, I. N., Darby, M. G., Dharmage, S. C., Gómez-Real, F., Hammer, B., Bertelsen, R. J., Johannessen, A., Würtz, A. M. L., Mørkve Knudsen, T., Koplin, J., Pape, K., Skulstad, S. M., Timm, S., Tjalvin, G., Krauss-Etschmann, S., Accordini, S., … Svanes, C.
Pubblicato in:
International Journal of Environmental Research and Public Health, Numero 18 (23), 2021, Pagina/e 12684, ISSN 1660-4601
Editore:
MDPI
DOI:
10.3390/ijerph182312684
Autori:
Svetlana Solovieva, Alexis Descatha, Ingrid Sivesind Mehlum, Eira Viikari-Juntura, Karina Undem, Karin Berglund, Fabien Gilbert, Francesca Wuytack, Angelo d’Errico, Kathryn Badarin, Bradley Evanoff, Katarina Kjellberg
Pubblicato in:
Scandinavian Journal of Work, Environment & Health, Numero 51, 2025, Pagina/e 119-129, ISSN 0355-3140
Editore:
Nordic Association of Occupational Safety and Health (NOROSH)
DOI:
10.5271/sjweh.4203
Autori:
Kirsten Nabe-Nielsen, Anne Emily Saunte Fiehn Arup, Mette Sallerup, Rikke Harmsen, Anna Sofie Ginty, Marie Tolver Nielsen, Anne-Sofie Rosenfeldt Jensen, Anders Aagaard, Vivi Schlünssen, Ann Dyreborg Larsen, Anne Helene Garde
Pubblicato in:
European Journal of Epidemiology, Numero 40, 2025, Pagina/e 371-382, ISSN 0393-2990
Editore:
Kluwer Academic Publishers
DOI:
10.1007/s10654-025-01201-4
Autori:
Susan Peters, Karina Undem, Svetlana Solovieva, Jenny Selander, Vivi Schlünssen, Karen M Oude Hengel, Maria Albin, Calvin B Ge, Katarina Kjellberg, Damien M McElvenny, Per Gustavsson, Henrik A Kolstad, Anne Mette L Würtz, Bendik C Brinchmann, Karin Broberg, Stine Fossum, Merete Bugge, Mette Wulf Christensen, Manosij Ghosh, David Høyrup Christiansen, Suzanne L Merkus, Lars-Kristian Lunde, Eira V
Pubblicato in:
Annals of Work Exposures and Health, Numero 68; 6, 2024, Pagina/e 562-580, ISSN 2398-7308
Editore:
Oxford Academic
DOI:
10.1093/annweh/wxae045
Autori:
Tara van der Grinten, Daniella van de Langenberg, Linda van Kerkhof, Barbara N. Harding, Anne Helene Garde, Caisa Laurell, Roel Vermeulen, Susan Peters, Jelle Vlaanderen
Pubblicato in:
Frontiers in Public Health, Numero 13, 2025, ISSN 2296-2565
Editore:
Frontiers Media SA
DOI:
10.3389/fpubh.2025.1578128
Autori:
Karen M Oude Hengel, Susan Peters, Zara A Stokholm, Alex Burdorf, Anjoeka Pronk, Henrik A Kolstad, Martie van Tongeren, Ioannis Basinas, Vivi Schlünssen
Pubblicato in:
Scandinavian Journal of Work, Environment & Health, 2025, ISSN 0355-3140
Editore:
Nordic Association of Occupational Safety and Health (NOROSH)
DOI:
10.5271/sjweh.4235
Autori:
Oude Hengel KM, Burdorf A, Pronk A, Schlünssen V, Stokholm ZA, Kolstad HA, van Veldhoven K, Basinas I, van Tongeren M, Peters S
Pubblicato in:
Scand J Work Environ Health, Numero 48 (1), 2021, Pagina/e 61-70, ISSN 0355-3140
Editore:
Nordic Association of Occupational Safety and Health (NOROSH)
DOI:
10.5271/sjweh.3998
Autori:
Alicia Guillien, Manosij Ghosh, Thomas Gille, Orianne Dumas
Pubblicato in:
Breathe, Numero 19, 2023, Pagina/e 23044, ISSN 1810-6838
Editore:
European Respiratory Society
DOI:
10.1183/20734735.0044-2023
Autori:
Vivi Schlünssen, Jean Baptist du Prel, Martie van Tongeren, Lode Godderis, Michelle C Turner, and Damien McElvenny, OMEGA-NET COVID-19 Questionnaire Subtask Group
Pubblicato in:
Annals of Work Exposures and Health, Numero 67(1), 2023, Pagina/e 4-8, ISSN 2398-7308
Editore:
Oxford University Press
DOI:
10.1093/annweh/wxac044
Autori:
Wenxin Wan, Calvin B Ge, Melissa C Friesen, Sarah J Locke, Daniel E Russ, Igor Burstyn, Christopher J O Baker, Anil Adisesh, Qing Lan, Nathaniel Rothman, Anke Huss, Martie van Tongeren, Roel Vermeulen, Susan Peters
Pubblicato in:
Annals of Work Exposures and Health, Numero 67; 5, 2023, Pagina/e 663-672, ISSN 2398-7316
Editore:
Oxford Academic
DOI:
10.1093/annweh/wxad002
Autori:
Mathijs A. Langezaal; Egon L. van den Broek; Susan Peters; Marcel Goldberg; Grégoire Rey; Melissa C. Friesen; Sarah J. Locke; Nathaniel Rothman; Qing Lan; Roel C. H. Vermeulen
Pubblicato in:
Communications Medicine, Numero 3(1), 2023, Pagina/e 160, ISSN 2730-664X
Editore:
Springer Nature
DOI:
10.1038/s43856-023-00397-4
Autori:
Rachel L Hasting, Suzanne L Merkus, Karina Undem, Jorunn Kirkeleit, Rune Hoff, Jon Michael Gran, Karl-Christian Nordby, Ingrid S Mehlum
Pubblicato in:
International Journal of Epidemiology, Numero 54, 2025, ISSN 1464-3685
Editore:
Oxford University Press (OUP)
DOI:
10.1093/ije/dyaf019
Autori:
Verscheure, Eline; Schlünssen, Vivi; Broberg, Karin; Makris, Konstantinos; Charisiadis,Pantelis; Narui, Shan; Samulin Erdem, Johanna; Harding, Barbara; Kogevinas, Manolis; Samuel, Helen; Murch, William; Christie, Francesca; Schaber, Chad; Stierum, Rob; Pronk, Anjoeka; Godderis, Lode; Ghosh, Manosij
Pubblicato in:
2023
Editore:
KUL
DOI:
10.48804/9s65kb
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