Single-Use unit and Process Analytical Infrared Spectroscopy

Informacje na temat projektu

SUPAIR Spectroscopy

Identyfikator umowy o grant: 954732

DOI

10.3030/954732

Projekt został zamknięty

Data podpisania przez KE 30 Kwietnia 2020

Data rozpoczęcia 1 Maja 2020

Data zakończenia 30 Kwietnia 2022

Finansowanie w ramach

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Koszt całkowity

€ 1 880 327,50

Wkład UE

€ 1 316 229,25

Koordynowany przez

IRUBIS GMBH
Germany

Periodic Reporting for period 2 - SUPAIR Spectroscopy (Single-Use unit and Process Analytical Infrared Spectroscopy)

Okres sprawozdawczy: 2021-02-01 do 2022-04-30

Podsumowanie kontekstu i ogólnych celów projektu

IRUBIS GmbH developed within the project a novel analytical device that enables continuous real-time monitoring of bioprocesses using mid-infrared spectroscopy with a single use flow cell. Its market is in process development and manufacturing of biological drugs, such as vaccines. The objective of ‘SUPAIR Spectroscopy’ project was to develop the mid-infrared spectroscopy system in line with the biopharma user requirements and to lay the groundwork for successful market commercialization. The validation and feedback by biopharma companies was essential for the project. Additionally, their feedback as well as the promotion of the results laid the foundation for the commercialization strategy.

Prace wykonane od początku projektu do końca okresu sprawozdawczego oraz najważniejsze dotychczasowe rezultaty

During the first 9 month of the action the hardware and software were developed: a monitoring and control solution, including an algorithm that can monitor glucose and lactate, without extensive calibration model building and a control feature to keep the glucose concentration at a constant level. During the second period ‘Monipa’ was validated, and the manufacturing of the analytical device was adapted based on the feedback from biopharma users to achieve a suitable process analytical technology for the biopharma industry. In parallel a business innovation plan and commercialization plan has been developed and dissemination as well as exploitation activities conducted.

Innowacyjność oraz oczekiwany potencjalny wpływ (w tym dotychczasowe znaczenie społeczno-gospodarcze i szersze implikacje społeczne projektu)

We see the future impact of ‘Monipa’ on the one hand by enabling an increase of the product gain and to achieve higher quality of biopharmaceutical drugs by a continuous control of the nutrient parameter in the bioprocess. On the other hand, a continuous control and real-time monitoring of nutrients and metabolites in the bioprocess leads to a higher process know-how and decrease the time for process development. In a consequence the new technology brings biopharmaceuticals faster to the patient.

Monipa, real-time monitoring of bioprocesses