Cel Interesting new compounds have been isolated from marine sponges: e.g. cytotoxic compounds that may be used as anti-cancer drugs, antibiotics, anti-viral agents and compounds with anti-inflammatory and cardiovascular properties. Biotechnological production under well defined conditions of sponge biomass is a necessary step towards commercialization of these potentially interesting products. So far, no primary-cell suspension cultures showed growth. Sponge cells need cell-cell contact to proliferate. In order to obtain axenic sponge tissue cultures, sponges can be dissociated, cleaned from other organisms than the sponge cells and reaggregated. Primary cell cultures can be reaggregated to strong spherical aggregates, primmorphs. The goal is to develop a process for in vitro cultivation of marine sponges for the production of biological active compounds. Sponges will be grown as primmorphs in bioreactors. Optimisation of the growth of and isolation of bioactive components from these primmorphs is the main objective of the project. A process design (including the market analysis) will be made. Dziedzina nauki engineering and technologyenvironmental biotechnologybioremediationbioreactorsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsagricultural sciencesagricultural biotechnologybiomass Program(-y) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Temat(-y) 1.1.1.-3. - Key action The "Cell factory" Zaproszenie do składania wniosków Data not available System finansowania CSC - Cost-sharing contracts Koordynator WAGENINGEN UNIVERSITY Wkład UE Brak danych Adres Costerweg 50 WAGENINGEN Niderlandy Zobacz na mapie Linki Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (4) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko JOHANNES GUTENBERG UNIVERSITAET MAINZ Niemcy Wkład UE Brak danych Adres 6,Duesbergweg 6 55099 MAINZ Zobacz na mapie Koszt całkowity Brak danych KLINIPHARM DIA MED VERTRIEBS GMBH Niemcy Wkład UE Brak danych Adres Hochstrasse 2 60313 FRANKFURT AM-MAIN Zobacz na mapie Koszt całkowity Brak danych NATIONAL INSTITUTE OF CHEMICAL PHYSICS AND BIOPHYSICS Estonia Wkład UE Brak danych Adres 23,Akademia Tee 23 12618 TALLINN Zobacz na mapie Koszt całkowity Brak danych NATIONAL RESEARCH COUNCIL OF ITALY Włochy Wkład UE Brak danych Adres Piazzale Aldo Moro 7 00185 ROMA Zobacz na mapie Koszt całkowity Brak danych