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Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine

Rezultaty

Communication and public engagement plan No. 1
Report on workshops/Networking activities

Report on Workshop List of attendees work programme workshop results summary audiovisual material and slides Networking activities Events future potential collaborative project

Communication and public engagement plan No. 2
Microfluidic chip modelling the Duchenne Muscular

A microfluidic chip will be designed for modelling the Duchenne Muscular Dystrophy (DMD) cardiomyopathy

Microfluidic device for iPSC differentiation into Cardiomyocyte

Fabrication of microfluidic device dedicated to the iPSC differentiation into cardiomyocyte. The microfluidic chip will exploit a biochemical procedure for iPSC differentiation. This first prototype will be fabricated in PDMS.

Publikacje

Surface modifications of COP-based microfluidic devices for improved immobilisation of hydrogel proteins: long-term 3D culture with contractile cell types and ischaemia model

Autorzy: Sandra González-Lana; Teodora Randelovic; Jesús Ciriza; María López-Valdeolivas; Rosa Monge; Carlos Sánchez-Somolinos; Ignacio Ochoa
Opublikowane w: Lab on a chip, Numer 8, 2023, ISSN 1473-0197
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3lc00075c

Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling

Autorzy: María Virumbrales-Muñoz, Jose M. Ayuso, Alodia Lacueva, Teodora Randelovic, Megan K. Livingston, David J. Beebe, Sara Oliván, Desirée Pereboom, Manuel Doblare, Luis Fernández, Ignacio Ochoa
Opublikowane w: Scientific Reports, Numer 9/1, 2019, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-019-42529-8

Towards novel biomimetic in vitro models of the blood-brain barrier for drug permeability evaluation

Autorzy: Mármol, Inés; Abizanda-Campo, Sara; Ayuso, José M.; Ochoa, Ignacio; Oliván, Sara
Opublikowane w: Bioengineering, Numer 10, 2023, ISSN 2306-5354
Wydawca: mdpi
DOI: 10.3390/bioengineering10050572

Current approaches for the recreation of cardiac ischaemic environment in vitro

Autorzy: Laura Paz-Artigas, Pilar Montero-Calle, Olalla Iglesias-García, Manuel M. Mazo, Ignacio Ochoa , Jesús Ciriza
Opublikowane w: International Journal of Pharmaceutics, 2023, ISSN 0378-5173
Wydawca: Elsevier BV
DOI: 10.1016/j.ijpharm.2023.122589

Gene therapy. The legacy of Wacław Szybalski.

Autorzy: Jozef Dulak
Opublikowane w: Acta Biochimica Polonica, Numer 5, 2020, ISSN 1734-154X
Wydawca: Polskie Towarzystwo Biochemiczne
DOI: 10.18388/abp.2020_5805

Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells

Autorzy: Alicja Martyniak, Mateusz Jeż, Józef Dulak, Jacek Stępniewski
Opublikowane w: IUBMB Life, 2023, ISSN 1521-6551
Wydawca: John Wiley & Sons
DOI: 10.1002/iub.2685

Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research

Autorzy: Kalina Andrysiak; Jacek Stępniewski; Jozef Dulak
Opublikowane w: Pflugers Archiv - European Journal of Physiology, Numer 3, 2021, ISSN 0031-6768
Wydawca: Springer Verlag
DOI: 10.1007/s00424-021-02536-z

Heart-on-a-chip

Autorzy: Pierre Gaudriault, Dario Fassini, Antoni Homs-Corbera
Opublikowane w: Organ-on-a-chip, 2020, Strona(/y) 255-293, ISBN 9780128172025
Wydawca: Elsevier
DOI: 10.1016/b978-0-12-817202-5.00008-5

Application of human induced pluripotent stem cells and CRISPR/Cas9 gene editing technology for investigation of molecular background of Duchenne muscular dystrophy-related cardiomyopathy

Autorzy: Kalina Andrysiak
Opublikowane w: 2022
Wydawca: Repozytorium Uniwersytetu Jagiellońskiego

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