Challenging current models of valence encoding in the mammalian brain

Informacje na temat projektu

VALENCE

Identyfikator umowy o grant: 101003187

DOI

10.3030/101003187

Data podpisania przez KE 4 Lutego 2021

Data rozpoczęcia 1 Maja 2021

Data zakończenia 30 Kwietnia 2027

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 988 266,00

Wkład UE

€ 1 988 266,00

Koordynowany przez

UNIVERSIDADE DO MINHO
Portugal

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan of project VALENCE

Publikacje

Peer reviewed articles (19)

Chronic stress and cytogenesis ablation disrupt hippocampal neuron connectivity, with fluoxetine restoring function with sex-specific effects

Autorzy: Inês Ribeiro, Tiago Silveira-Rosa, Joana Martins-Macedo, Luísa Marques-Ferraz, Ana Rita Dourado, Gonçalo Martins-Ferreira, Fanny Farrugia, Ana João Rodrigues, Djoher Nora Abrous, Nuno Dinis Alves,
Opublikowane w: Neurobiology of Stress, Numer 37, 2025, Strona(/y) 100743, ISSN 2352-2895
Wydawca: Elsevier BV
DOI: 10.1016/j.ynstr.2025.100743

Beyond New Neurons in the Adult Hippocampus: Imipramine Acts as a Pro-Astrogliogenic Factor and Rescues Cognitive Impairments Induced by Stress Exposure

Autorzy: Machado-Santos et al
Opublikowane w: Cells, 2022, ISSN 2073-4409
Wydawca: Wiley
DOI: 10.3390/cells11030390

Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods

Autorzy: Loureiro-Campos et al
Opublikowane w: eLife, 2021, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.70685.sa0

Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior

Autorzy: Soares-Cunha et al
Opublikowane w: Cell Reports, Numer 22111247, 2022, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2022.110380

Early life behavioral deficits and microglia remodeling in the mesocorticolimbic system precede the emergence of Schizophrenia-like symptoms

Autorzy: Ana C. Rodrigues-Neves, Jéssica Monteiro, Bárbara Coimbra, Rita Gaspar, Verónica Domingues, Carina Soares-Cunha, Patrícia Patrício, Marta I. Pereira, Ana L. Cardoso, Luísa Pinto, João Bessa, An
Opublikowane w: Brain, Behavior, and Immunity, Numer 129, 2025, Strona(/y) 416-433, ISSN 0889-1591
Wydawca: Academic Press
DOI: 10.1016/j.bbi.2025.06.009

Cell Cycle Regulation of Hippocampal Progenitor Cells in Experimental Models of Depression and after Treatment with Fluoxetine

Autorzy: Patricio et al
Opublikowane w: Int J Mol Sci, Numer 14220067, 2021, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222111798

Suppression of adult cytogenesis in the rat brain leads to sex-differentiated disruption of the HPA axis activity

Autorzy: Tiago Silveira-Rosa, António Mateus-Pinheiro, Joana Sofia Correia, Joana Margarida Silva, Joana Martins-Macedo, Bruna Araújo, Ana Rita Machado-Santos, Nuno Dinis Alves, Mariana Silva, Eduardo Loureiro-Campos, Ioannis Sotiropoulos, João Miguel Bessa, Ana João Rodrigues, Nuno Sousa, Patrícia Patrício, Luísa Pinto
Opublikowane w: Cell proliferation, 2022, ISSN 0960-7722
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/cpr.13165

Involvement of nucleus accumbens D2–medium spiny neurons projecting to the ventral pallidum in anxiety-like behaviour

Autorzy: Raquel Correia, Bárbara Coimbra, Ana Verónica Domingues, Marcelina Wezik, Natacha Vieitas-Gaspar, Rita Gaspar, Nuno Sousa, Luísa Pinto, Ana João Rodrigues and Carina Soares-Cunha
Opublikowane w: J Psychiatry Neurosci, 2023, ISSN 1180-4882
Wydawca: Canadian Medical Association/Association Medical Canadienne
DOI: 10.1503/jpn.220111

Dopamine in the nucleus accumbens in valence-based learning: is it really important?

Autorzy: Ana João Rodrigues
Opublikowane w: Current Opinion in Behavioral Sciences, Numer 61, 2025, Strona(/y) 101462, ISSN 2352-1546
Wydawca: Elsevier Limited
DOI: 10.1016/j.cobeha.2024.101462

Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation

Autorzy: Joana Martins-Macedo, Bruna Araújo, Sandra I. Anjo, Tiago Silveira-Rosa, Patrícia Patrício, Nuno Dinis Alves, Joana M. Silva, Fábio G. Teixeira, Bruno Manadas, Ana J. Rodrigues, Angelo C. Lepore,
Opublikowane w: Molecular Psychiatry, Numer 29, 2024, Strona(/y) 2185-2198, ISSN 1359-4184
Wydawca: Nature Publishing Group
DOI: 10.1038/s41380-024-02490-z

From valence encoding to motivated behavior: A focus on the nucleus accumbens circuitry

Autorzy: Natacha Vieitas-Gaspar, Carina Soares-Cunha, Ana João Rodrigues
Opublikowane w: Neuroscience & Biobehavioral Reviews, Numer 172, 2025, Strona(/y) 106125, ISSN 0149-7634
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2025.106125

The Duration of Stress Determines Sex Specificities in the Vulnerability to Depression and in the Morphologic Remodeling of Neurons and Microglia

Autorzy: Gaspar et al
Opublikowane w: Front. Behav. Neurosci, Numer 16625153, 2022, ISSN 1662-5153
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnbeh.2022.834821

StressMatic: A Novel Automated System to Induce Depressive- and Anxiety-like Phenotype in Rats

Autorzy: Martins-Macedo et al.
Opublikowane w: Cells, 2023, ISSN 2073-4409
Wydawca: MDPI
DOI: 10.3390/cells12030381

Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning

Autorzy: Deseyve et al
Opublikowane w: Journal of Neurochemistry, 2024, ISSN 0022-3042
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jnc.16063

Fabrication, Electrochemical Characterization, and In Vivo Validation of a Flexible Neural Probe

Autorzy: João R. Freitas, José A. Rodrigues, João L. Machado, Leandro A. A. Aguiar, Ana J. Rodrigues, João F. Oliveira, José H. Correia, Sara Pimenta
Opublikowane w: Journal of Microelectromechanical Systems, Numer 34, 2025, Strona(/y) 482-487, ISSN 1057-7157
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jmems.2025.3579544

The mesopontine tegmentum in reward and aversion: From cellular heterogeneity to behaviour

Autorzy: Ricardo Bastos-Gonçalves, Bárbara Coimbra, Ana João Rodrigues
Opublikowane w: Neuroscience & Biobehavioral Reviews, Numer 162, 2024, Strona(/y) 105702, ISSN 0149-7634
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2024.105702

Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons

Autorzy: Ana Verónica Domingues, Tawan T. A. Carvalho, Gabriela J. Martins, Raquel Correia, Bárbara Coimbra, Ricardo Bastos-Gonçalves, Marcelina Wezik, Rita Gaspar, Luísa Pinto, Nuno Sousa, Rui M. Costa, C
Opublikowane w: Nature Communications, Numer 16, 2025, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-55269-9

In and Out of Criticality? State-Dependent Scaling in the Rat Visual Cortex

Autorzy: Daniel M. Castro, Thaís Feliciano, Nivaldo A. P. de Vasconcelos, Carina Soares-Cunha, Bárbara Coimbra, Ana João Rodrigues, Pedro V. Carelli, Mauro Copelli
Opublikowane w: PRX Life, Numer 2, 2024, ISSN 2835-8279
Wydawca: American Physical Society (APS)
DOI: 10.1103/prxlife.2.023008

Prenatal dexamethasone exposure alters effort decision making and triggers nucleus accumbens and anterior cingulate cortex functional changes in male rats

Autorzy: Domingues et al
Opublikowane w: Translational Psychiatry, Numer 21583188, 2022, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.1038/s41398-022-02043-4

Non-peer reviewed articles (1)

State-dependent complexity of the local field potential in the primary visual cortex

Autorzy: Rafael M. Jungmann, Thaís Feliciano, Leandro A. A. Aguiar, Carina Soares-Cunha, Bárbara Coimbra, Ana João Rodrigues, Mauro Copelli, Fernanda S. Matias, Nivaldo A. P. de Vasconcelos, Pedro V. Carell
Opublikowane w: Physical Review E, Numer 110, 2024, ISSN 2470-0045
Wydawca: American Physical Society (APS)
DOI: 10.1103/physreve.110.014402