Biomarker Enterprise to Attack DKD - Sofia ref.: 115974 | BEAt-DKD | Project | Results | H2020 | CORDIS

Rezultaty

White paper on strengths and weaknesses of using biomarker panels (or multiple biomarker scores) as risk stratifiers, as targets in drug development and as surrogate endpoints for regulatory approval

Migration

Publikacje

Predictive Biomarkers in Nephrology Around the Corner

Autorzy: Paul Perco, Kumar Sharma
Opublikowane w: Kidney International Reports, Numer 5/1, 2020, Strona(/y) 1-3, ISSN 2468-0249
Wydawca: Elsevier
DOI: 10.1016/j.ekir.2019.10.009

Effects of albuminuria-lowering treatments on inflammation markers: A post hoc analysis from the ROTATE trials

Autorzy: Taha Sen, Viktor Rotbain Curovic, Niels Jongs, Gozewijn D Laverman, Adriaan Kooy, Frederik Persson, Peter Rossing, Hiddo J L Heerspink
Opublikowane w: Diabetes, Obesity and Metababolism, Numer Aug;25(8), 2023, Strona(/y) 2413-2418, ISSN 1462-8902
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/dom.15109

Development and Validation of a Prediction Model for Future Estimated Glomerular Filtration Rate in People With Type 2 Diabetes and Chronic Kidney Disease

Autorzy: Mariella Gregorich, Michael Kammer, Andreas Heinzel, Carsten Böger, Kai-Uwe Eckardt, Hiddo Lambers Heerspink, Bettina Jung, Gert Mayer, Heike Meiselbach, Matthias Schmid,Ulla T. Schultheiss, Georg Heinze, Rainer Oberbauer, for the BEAt-DKD Consortium
Opublikowane w: JAMA Network Open, Numer 6(4), 2023, Strona(/y) e231870, ISSN 0098-7484
Wydawca: American Medical Association
DOI: 10.1001/jamanetworkopen.2023.1870

Surprising Hyperkalemia of 10.2 mmol/L in a Patient with Hyperglycemia: A Case Report

Autorzy: Czogalla J, Tariparast P.A, Huber T.B, Janneck M, Grahammer F
Opublikowane w: Case Reports in Nephrology and Dialysis, Numer 11/1, 2021, Strona(/y) 69–77, ISSN 2296-9705
Wydawca: S. Karger AG.
DOI: 10.1159/000512590

Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy

Autorzy: Shuya Liu, Yu Zhao, Shun Lu, Tianran Zhang, Maja T. Lindenmeyer, Viji Nair, Sydney E. Gies, Guochao Wu, Robert G. Nelson, Jan Czogalla, Hande Aypek, Stephanie Zielinski, Zhouning Liao, Melanie Schaper, Damian Fermin, Clemens D. Cohen, Denis Delic, Christian F. Krebs, Florian Grahammer, Thorsten Wiech, Matthias Kretzler, Catherine Meyer-Schwesinger, Stefan Bonn, Tobias B. Huber
Opublikowane w: Genome Medicine, Numer Vol. 106, No. 2, 2023, Strona(/y) 388–396, ISSN 1756-994X
Wydawca: BioMed Central
DOI: 10.1186/s13073-022-01145-4

Assessment of Fibrinogen-like 2 (FGL2) in Human Chronic Kidney Disease through Transcriptomics Data Analysis

Autorzy: Sara Denicolò, Viji Nair, Johannes Leierer, Michael Rudnicki, Matthias Kretzler, Gert Mayer, Wenjun Ju, Paul Perco
Opublikowane w: Biomolecules, Numer 13(1), 89, 2023, ISSN 2218-273X
Wydawca: MDPI
DOI: 10.3390/biom13010089

Contribution of Real-World Evidence in European Medicines Agency's Regulatory Decision Making

Autorzy: Elisabeth Bakker, Kelly Plueschke, Carla J Jonker, Xavier Kurz, Viktoriia Starokozhko, Peter G M Mol
Opublikowane w: Clinical Pharmacology Therapeutics, Numer Jan;113(1), 2023, Strona(/y) 135-151, ISSN 0009-9236
Wydawca: Nature Publishing Group
DOI: 10.1002/cpt.2766

Cardiovascular risk due to diabetes mellitus in patients with chronic kidney disease—prospective data from the German Chronic Kidney Disease cohort

Autorzy: Johannes Ruhe, Jennifer Nadal, Barbara Bärthlein, Heike Meiselbach, Ulla T Schultheiss, Fruzsina Kotsis, Helena Stockmann, Vera Krane, Claudia Sommerer, Ivonne Löffler, Turgay Saritas, Jan T Kielstein, Thomas Sitter, Markus P Schneider, Matthias Schmid, Christoph Wanner, Kai-Uwe Eckardt, Gunter Wolf, Martin Busch
Opublikowane w: Clin Kidney J, Numer 16(11), 2023, Strona(/y) 2032-2040, ISSN 2048-8505
Wydawca: Oxford University Press
DOI: 10.1093/ckj/sfad194

Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy

Autorzy: Fabian Braun, Ahmed Abed, Dominik Sellung, Manuel Rogg, Mathias Woidy, Oysten Eikrem, Nicola Wanner, Jessica Gambardella, Sandra D Laufer, Fabian Haas, Milagros N Wong, Bernhard Dumoulin, Paula Rischke, Anne Mühlig, Wiebke Sachs, Katharina von Cossel, Kristina Schulz, Nicole Muschol, Sören W Gersting, Ania C Muntau, Oliver Kretz, Oliver Hahn, Markus M Rinschen, Michael Mauer, Tillmann Bork, Flor
Opublikowane w: Journal of Clinical Investigation, Numer Jun 1;133(11), 2023, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci157782

Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development

Autorzy: Danielle Vaughan, Olli Ritvos, Robert Mitchell, Oliver Kretz, Maciej Lalowski, Helge Amthor, David Chambers, Antonios Matsakas, Arja Pasternack, Henry Collins-Hooper, Randy Ballesteros, Tobias B. Huber, Bernd Denecke, Darius Widera, Abir Mukherjee, Ketan Patel
Opublikowane w: European Journal of Translational Myology, Numer 30/1, 2020, Strona(/y) 62-78, ISSN 2037-7460
Wydawca: PAGEPress Publications
DOI: 10.4081/ejtm.2019.8737

Differential prognostic utility of adiposity measures in chronic kidney disease

Autorzy: Vladimir Cejka, Jennifer Nadal, Matthias Schmid, Claudia Sommerer, Thomas Sitter, Heike Meiselbach. Martin Busch, Markus P Schneider, Turgay Saritas, Ulla T Schultheiss, Fruzsina Kotsis, Christoph Wanner, Kai-Uwe Eckardt, Vera Krane, GCKD Investigators.
Opublikowane w: J Renal Nutr, Numer 33(4), 2023, Strona(/y) 546-554, ISSN 1532-8503
Wydawca: Saunders
DOI: 10.1053/j.jrn.2023.04.006

Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis

Autorzy: Eva M Buhl, Sonja Djudjaj, Barbara M Klinkhammer, Katja Ermert, Victor G Puelles, Maja T Lindenmeyer, Clemens D Cohen, Chaoyong He, Erawan Borkham‐Kamphorst, Ralf Weiskirchen, Bernd Denecke, Panuwat Trairatphisan, Julio Saez‐Rodriguez, Tobias B Huber, Lorin E Olson, Jürgen Floege, Peter Boor
Opublikowane w: EMBO Molecular Medicine, Numer 12/3, 2020, ISSN 1757-4676
Wydawca: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201911021

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

Autorzy: Mathias Gorski, Humaira Rasheed, Alexander Teumer, Laurent F Thomas, Sarah E Graham, Gardar Sveinbjornsson, Thomas W Winkler, Felix Günther, Klaus J Stark, Jin-Fang Chai, Bamidele O Tayo, Matthias Wuttke, Yong Li, Adrienne Tin, Tarunveer S Ahluwalia, Johan Ärnlöv, Bjørn Olav Åsvold, Stephan J L Bakker, Bernhard Banas, Nisha Bansal, Mary L Biggs, Ginevra Biino, Michael Böhnke, Eric Boerwinkle
Opublikowane w: Kidney international, Numer 102(3), 2022, Strona(/y) 624-39, ISSN 0085-2538
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2022.05.021

Blocking matrix metalloproteinase-mediated syndecan-4 shedding restores the endothelial glycocalyx and glomerular filtration barrier function in early diabetic kidney disease

Autorzy: Raina D. Ramnath, Matthew J. Butler, Georgina Newman, Sara Desideri, Amy Russell, Abigail C. Lay, Chris R. Neal, Yan Qiu, Sarah Fawaz, Karen L. Onions, Monica Gamez, Michael Crompton, Chris Michie, Natalie Finch, Richard J. Coward, Gavin I. Welsh, Rebecca R. Foster, Simon C. Satchell
Opublikowane w: Kidney International, Numer 97/5, 2020, Strona(/y) 951-965, ISSN 0085-2538
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2019.09.035

Consensus-Based Technical Recommendations for Clinical Translation of Renal Phase Contrast MRI

Autorzy: Anneloes de Boer MD,Giulia Villa MS,Octavia Bane PhD,Michael Bock PhD,Eleanor F. Cox PhD,Ilona A. Dekkers MD, PhD,Per Eckerbom MD,Maria A. Fernández-Seara PhD,Susan T. Francis PhD,Bryan Haddock PhD,Michael E. Hall MD,Pauline Hall Barrientos PhD,Ingo Hermann MS,Paul D. Hockings PhD,Hildo J. Lamb MD, PhD,Christoffer Laustsen PhD,Ruth P. Lim MD,David M. Morris PhD,Steffen Ringgaard PhD,Suraj D. Sera
Opublikowane w: Journal of Magnetic Resonance Imaging, 2020, ISSN 1053-1807
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/jmri.27419

Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA

Autorzy: Iosif Mendichovszky, Pim Pullens, Ilona Dekkers, Fabio Nery, Octavia Bane, Andreas Pohlmann, Anneloes de Boer, Alexandra Ljimani, Aghogho Odudu, Charlotte Buchanan, Kanishka Sharma, Christoffer Laustsen, Anita Harteveld, Xavier Golay, Ivan Pedrosa, David Alsop, Sean Fain, Anna Caroli, Pottumarthi Prasad, Susan Francis, Eric Sigmund, Maria Fernández‐Seara, Steven Sourbron
Opublikowane w: Magnetic Resonance Materials in Physics, Biology and Medicine, Numer 33/1, 2020, Strona(/y) 131-140, ISSN 0968-5243
Wydawca: Springer Verlag
DOI: 10.1007/s10334-019-00784-w

Interleukin-6 and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes: New Insights From CANVAS

Autorzy: Akihiko Koshino, Meir Schechter, Taha Sen , Priya Vart, Brendon L Neuen, Bruce Neal, Clare Arnott , Vlado Perkovic, Paul M Ridker, Katherine R Tuttle, Michael K Hansen, Hiddo J L Heerspink
Opublikowane w: Diabetes Care, Numer Nov 1;45(11), 2022, Strona(/y) 2644-2652, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dc22-0866

Machine‐learning–based early prediction of end‐stage renal disease in patients with diabetic kidney disease using clinical trials data

Autorzy: Sunil Belur Nagaraj, Michelle J. Pena, Wenjun Ju, Hiddo L. Heerspink
Opublikowane w: Diabetes, Obesity and Metabolism, Numer 22/12, 2020, Strona(/y) 2479-2486, ISSN 1462-8902
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/dom.14178

A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities

Autorzy: Danielle Vaughan, Robert Mitchell, Oliver Kretz, David Chambers, Maciej Lalowski, Helge Amthor, Olli Ritvos, Arja Pasternack, Antonios Matsakas, Sakthivel Vaiyapuri, Tobias B. Huber, Bernd Denecke, Abir Mukherjee, Darius Widera, Ketan Patel
Opublikowane w: Disease Models & Mechanisms, Numer 14/2, 2020, ISSN 1754-8403
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/dmm.047555

Effect of empagliflozin on kidney biochemical and imaging outcomes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF)

Autorzy: Matthew M.Y. Lee, Keith A. Gillis, Katriona J.M. Brooksbank, Sarah Allwood-Spiers, Pauline Hall Barrientos, Kirsty Wetherall, Giles Roditi, Bashair AlHummiany, Colin Berry, Ross T. Campbell, Victor Chong, Liz Coyle, Kieran F. Docherty, John G. Dreisbach, Bernd Kuehn, Catherine Labinjoh, Ninian N. Lang, Vera Lennie, Kenneth Mangion, Alex McConnachie, Clare L. Murphy, Colin J. Petrie, John R. Petrie
Opublikowane w: Circulation, Numer 146, 2022, Strona(/y) 364–367, ISSN 0009-7322
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.122.059851

Validation of a Novel Predictive Algorithm for Kidney Failure in Patients Suffering from Chronic Kidney Disease: The Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD)

Autorzy: Francesco Bellocchio; Caterina Lonati; Jasmine Ion Titapiccolo; Jennifer Nadal; Heike Meiselbach; Matthias Schmid; Barbara Baerthlein; Ulrich Tschulena; Markus P. Schneider; Ulla T. Schultheiss; Carlo Barbieri; Christoph Moore; Sonja Steppan; Kai-Uwe Eckardt; Stefano Stuard; Luca Neri
Opublikowane w: International Journal of Environmental Research and Public Health,, Numer Vol 18, Iss 12649, 2021, Strona(/y) p 12649, ISSN 1660-4601
Wydawca: MDPI
DOI: 10.3390/ijerph182312649

Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens.

Autorzy: Dominik Kylies, Marina Zimmermann, Fabian Haas, Maria Schwerk, Malte Kuehl, Michael Brehler, Jan Czogalla, Lola C Hernandez, Leonie Konczalla, Yusuke Okabayashi, Julia Menzel, Ilka Edenhofer, Sam Mezher, Hande Aypek, Bernhard Dumoulin, Hui Wu, Smilla Hofmann, Oliver Kretz, Nicola Wanner, Nicola M Tomas, Susanne Krasemann, Markus Glatzel, Christoph Kuppe, Rafael Kramann, Bella Banjanin, Rebekka K S
Opublikowane w: Nature Nanotechnology, Numer Apr;18(4), 2023, Strona(/y) 336-342, ISSN 1748-3387
Wydawca: Nature Publishing Group
DOI: 10.1038/s41565-023-01328-z

Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease

Autorzy: Pradeep Bompada, Isabel Goncalves , Chuanyan Wu, Rui Gao, Jiangming Sun, Bilal Ahmad Mir, Cheng Luan, Erik Renström, Leif Groop, Jianping Weng, Ola Hansson, Jianping Weng, Ola Hansson, Andreas Edsfeldt, Yang De Marinis
Opublikowane w: Biomedicines, Numer 22279059, 2021, ISSN 2227-9059
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomedicines9121908

Kv1.3 Channel, a Targetable Piece in the Complex Jigsaw Puzzle of Vascular Calcification?

Autorzy: Maria F Gomez
Opublikowane w: Function, Numer 2/1, 2021, ISSN 2633-8823
Wydawca: Oxford University Press
DOI: 10.1093/function/zqaa049

Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease

Autorzy: Om Prakash Dwivedi, Karina Barreiro, Annemari Käräjämäki, Erkka Valo, Anil K Giri, Rashmi B Prasad, Rishi Das Roy, Lena M Thorn, Antti Rannikko, Harry Holthöfer, Kim M Gooding, Steven Sourbron, Denis Delic, Maria F Gomez; iBEAt; Per-Henrik Groop, Tiinamaija Tuomi, Carol Forsblom, Leif Groop, Maija Puhka
Opublikowane w: iScience, Numer 26, 2023, Strona(/y) 106686, ISSN 2589-0042
Wydawca: Cell Press
DOI: 10.1016/j.isci.2023.106686

A novel drug response score more accurately predicts renoprotective drug effects than existing renal risk scores

Autorzy: Nienke M. A. Idzerda, Sok Cin Tye, Dick de Zeeuw, Hiddo J. L. Heerspink
Opublikowane w: Therapeutic Advances in Endocrinology and Metabolism, Numer 12, 2021, ISSN 2042-0188
Wydawca: Sage Periodicals Press
DOI: 10.1177/2042018820974191

Correlates and Consequences of an Acute Change in eGFR in Response to the SGLT2 Inhibitor Dapagliflozin in Patients with CKD

Autorzy: Niels Jongs; Glenn M. Chertow; Tom Greene; John J.V. McMurray; Anna Maria Langkilde; Ricardo Correa-Rotter; Naoki Kashihara; Peter Rossing; C. David Sjöström; Bergur V. Stefánsson; Robert D. Toto; David C. Wheeler; Hiddo J.L. Heerspink
Opublikowane w: J Am Soc Nephrol, Numer 33(11), 2023, Strona(/y) 2094-2107, ISSN 1533-3450
Wydawca: ASN
DOI: 10.1681/asn.2022030306

Non-adherence to antidiabetic and cardiovascular drugs in type 2 diabetes mellitus and its association with renal and cardiovascular outcomes: A narrative review

Autorzy: Sara Denicolò, Paul Perco, Stefanie Thöni, Gert Mayer
Opublikowane w: J Diabetes Compl, Numer Vol 35, Numer 7, 2021, Strona(/y) 107931, ISSN 1873-460X
Wydawca: Elsevier
DOI: 10.1016/j.jdiacomp.2021.107931

BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk.

Autorzy: Bork T, Liang W, Kretz O, Lagies S, Yamahara K, Hernando-Erhard C, Helmstädter M, Schell C, Kammerer B, Huber TB
Opublikowane w: International Journal of Molecular Sciences, Numer 14220067, 2022, Strona(/y) 3825, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23073825

Vallidation of the classification for type 2 diabetes into five subgroups: a report from the ORIGIN trial.

Autorzy: Marie Pigeyre, Sibylle Hess, Maria F Gomez, Olof Asplund, Leif Groop, Guillaume Paré, Hertzel Gerstein.
Opublikowane w: Diabetologia, Numer 65, 2022, Strona(/y) 206-215, ISSN 1432-0428
Wydawca: Springer
DOI: 10.1007/s00125-021-05567-4

Baseline urinary metabolites predict albuminuria response to spironolactone in type 2 diabetes

Autorzy: Skander Mulder, Paul Perco, Christina Oxlund, Uzma F. Mehdi, Thomas Hankemeier, Ib A. Jacobsen, Robert Toto, Hiddo J.L. Heerspink, Michelle J. Pena
Opublikowane w: Translational Research, Numer 222, 2020, Strona(/y) 17-27, ISSN 1931-5244
Wydawca: Elsevier BV
DOI: 10.1016/j.trsl.2020.04.010

International Variability of Renal and Cardiovascular Outcomes and Mortality in Patients with Type 2 Diabetes Mellitus in Europe

Autorzy: Stefanie Thöni, Felix Keller, Sara Denicolò, Susanne Eder, Lukas Buchwinkler, Laszlo Rosivall, Andrzej Wiecekc, Patrick B. Mark, Peter Rossinge, Hiddo L. Heerspink, Gert Mayer
Opublikowane w: Kidney & Blood Pressure Research, Numer 48, 2023, Strona(/y) 165–174, ISSN 1420-4096
Wydawca: S. Karger AG
DOI: 10.1159/000528438

Prediction of the Effects of Liraglutide on Kidney and Cardiovascular Outcomes Based on Short-Term Changes in Multiple Risk Markers

Autorzy: Sok Cin Tye, Sieta T. de Vries, Johannes F. E. Mann, Meir Schechter, Ofri Mosenzon, Petra Denig and Hiddo J. L. Heerspink
Opublikowane w: Frontiers in Pharmacology, Numer 16639812, 2022, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.786767

Prediction of the Effects of Empagliflozin on Cardiovascular and Kidney Outcomes Based onShort-Term Changes in Multiple Risk Markers

Autorzy: Sok Cin Tye, Sieta T. de Vries, Christoph Wanner, Petra Denig and Hiddo J. L. Heerspink
Opublikowane w: Frontiers in Pharmacology, Numer 16639812, 2022, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2021.786706

Precision Prognostics for Cardiovascular Disease in Type 2 Diabetes: A Systematic Review and Meta-analysis

Autorzy: Abrar Ahmad, Lee-Ling Lim, Mario Luca Morieri, Claudia Ha-ting Tam, Feifei Cheng , Tinashe Chikowore, Monika Dudenhöffer-Pfeifer, Hugo Fitipaldi, Chuiguo Huang, Sarah Kanbour, Sudipa Sarkar, Robert Wilhelm Koivula, Ayesha A. Motala, Sok Cin Tye, Gechang Yu, Yingchai Zhang, Michele Provenzano, Diana Sherifali, Russell J. de Souza, Deirdre Kay Tobias, ADA/EASD PMDI23, Maria F. Gomez, Ronald C.W. Ma
Opublikowane w: Comm Medicine, Numer 4/11, 2024, ISSN 2730-664X
Wydawca: Nature Portfolio
DOI: 10.1038/s43856-023-00429-z

Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI

Autorzy: Ilona A. Dekkers, Anneloes de Boer, Kaniska Sharma, Eleanor F. Cox, Hildo J. Lamb, David L. Buckley, Octavia Bane, David M. Morris, Pottumarthi V. Prasad, Scott I. K. Semple, Keith A. Gillis, Paul Hockings, Charlotte Buchanan, Marcos Wolf, Christoffer Laustsen, Tim Leiner, Bryan Haddock, Johannes M. Hoogduin, Pim Pullens, Steven Sourbron, Susan Francis
Opublikowane w: Magnetic Resonance Materials in Physics, Biology and Medicine, Numer 33/1, 2020, Strona(/y) 163-176, ISSN 0968-5243
Wydawca: Springer Verlag
DOI: 10.1007/s10334-019-00797-5

Role of mTOR Signaling for Tubular Function and Disease

Autorzy: Grahammer F, Huber TB, Artunc F.
Opublikowane w: Physiology (Bethesda), Numer 15489213, 2021, Strona(/y) 350-358, ISSN 1548-9213
Wydawca: American Physiological Society
DOI: 10.1152/physiol.00021.2021

Prognostic imaging biomarkers for diabetic kidney disease (iBEAt): study protocol

Autorzy: Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball, Sapna Puppala, Mark Ibberson, Anil Karihaloo, Kaj Metsärinne, Rosamonde E. Banks, Peter S. Gilmour, Michael Mansfield, Mar
Opublikowane w: BMC Nephrology, Numer 21/1, 2020, ISSN 1471-2369
Wydawca: BioMed Central
DOI: 10.1186/s12882-020-01901-x

Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)

Autorzy: Matthew M.Y. Lee, Katriona J.M. Brooksbank, Kirsty Wetherall, Kenneth Mangion, Giles Roditi, Ross T. Campbell, Colin Berry, Victor Chong, Liz Coyle, Kieran F. Docherty, John G. Dreisbach, Catherine Labinjoh, Ninian N. Lang, Vera Lennie, Alex McConnachie, Clare L. Murphy, Colin J. Petrie, John R. Petrie, Iain A. Speirits, Steven Sourbron, Paul Welsh, Rosemary Woodward, Aleksandra Radjenovic, Patric
Opublikowane w: Circulation, Numer 143/6, 2021, Strona(/y) 516–525, ISSN 0009-7322
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.120.052186

Intra-individual variability of eGFR trajectories in early diabetic kidney disease and lack of performance of prognostic biomarkers

Autorzy: Julia Kerschbaum, Michael Rudnicki, Alexander Dzien, Christine Dzien-Bischinger, Hannes Winner, Hiddo Lambers Heerspink, László Rosivall, Andrzej Wiecek, Patrick B. Mark, Susanne Eder, Sara Denicolò, Gert Mayer
Opublikowane w: Scientific Reports, Numer 10, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-76773-0

The Cardiovascular Literature-Based Risk Algorithm (CALIBRA): Predicting Cardiovascular Events in Patients With Non-Dialysis Dependent Chronic Kidney Disease

Autorzy: Luca, Neri; Caterina, Lonati; Jasmine Ion, Titapiccolo; Jennifer, Nadal; Heike, Meiselbach; Matthias, Schmid; Barbara, Baerthlein; Ulrich, Tschulena; Markus P, Schneider; Ulla T, Schultheiss; Carlo, Barbieri; Christoph, Moore; Sonia, Steppan; Kai-Uwe, Eckardt; Stefano, Stuard; Francesco, Bellocchio
Opublikowane w: Front Nephrol, Numer 2, 2022, Strona(/y) 922251, ISSN 2813-0626
Wydawca: Frontiers Media SA
DOI: 10.3389/fneph.2022.922251

Large Between-Patient Variability in eGFR Decline before Clinical Trial Enrollment and Impact on Atrasentan’s Efficacy: A Post Hoc Analysis from the SONAR Trial

Autorzy: Simke W. Waijer, Sieta T. de Vries, Robert Busch, Di Xie, Ron T. Gansevoort, Fan Fan Hou, Jose L. Górriz, Gozewijn D. Laverman, Luca De Nicola, Julio Pascual, Michele Provenzano, Pablo E. Pergola, Sydney C.W. Tang, Christoph Wanner, Philippe Zaoui, Hans-Henrik Parving, Dick de Zeeuw and Hiddo J.L. Heerspink
Opublikowane w: Journal of the American Society of Nephrology, Numer 32 (11), 2021, Strona(/y) 2731-2734, ISSN 1046-6673
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2021040498

Clonal Hematopoiesis of Indeterminate Potential and Diabetic Kidney Disease: A Nested Case-Control Study.

Autorzy: Sara Denicolò, Verena Vogi, Felix Keller, Stefanie Thöni, Susanne Eder, Hiddo J.L. Heerspink , László Rosivall, Andrzej Wiecek, Patrick B. Mark, Paul Perco, Johannes Leierer, Andreas Kronbichler, Marion Steger, Simon Schwendinger, Johannes Zschocke, Gert Mayer, Emina Jukic
Opublikowane w: Kidney International Reports, Numer 24680249, 2022, Strona(/y) 876-888, ISSN 2468-0249
Wydawca: Elsevier
DOI: 10.1016/j.ekir.2022.01.1064

Inhibition of Lysine 63 ubiquitination prevents the progression of renal fibrosis in diabetic DBA/2J mice.

Autorzy: Paola Pontrelli, Francesca Conserva, Rossella Menghini, Michele Rossini, Alessandra Stasi, Chiara Divella, Viviana Casagrande, Claudia Cinefra, Mariagrazia Barozzino, Simona Simone, Francesco Pesce, Giuseppe Castellano, Giovanni Stallone, Anna Gallone, Francesco Giorgino, Massimo Federici and Loreto Gesualdo
Opublikowane w: International Journal of Molecular Sciences, Numer 14220067, 2021, Strona(/y) 5194, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22105194

The Relationship between AKI and CKD in Patients with Type 2 Diabetes: An Observational Cohort Study

Autorzy: Simona Hapca, Moneeza K. Siddiqui, Ryan S.Y. Kwan, Michelle Lim, Shona Matthew, Alex S.F. Doney, Ewan R. Pearson, Colin N.A. Palmer, Samira Bell
Opublikowane w: Journal of the American Society of Nephrology, Numer 32/1, 2020, Strona(/y) 138-150, ISSN 1046-6673
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2020030323

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