Rezultaty Documents, reports (9) D8.2 Report of International Force Field analysis workshop and identification of key areas for strategy development Report of International Force Field analysis workshop and identification of key areas for strategy development D1.5 End-term meeting together with BRIDGES Endterm meeting together with BRIDGESDelay due to COVID19 Due date to be moved to M66 BCAST planned deliverable D15 together with BRIDGES from 26th29th June 2020 in Leiden which has been cancelled due to the COVID19 crisis The purpose of the meeting was to disseminate the results of both BCAST and BRIDGES to the wider scientific community as the two consortia have worked synergistically for the last 5 years As the possibility of holding a physical meeting by Feb 2021 still appears slim we hope to get a further 6 month extension to be able to organise the meeting at a later point next year D4.2 Description of database for mammographic density Description of database for mammographic density D3.1 List of genes in panel for targeted DNA sequencing List of genes in panel for targeted DNA sequencing D4.1 Description of database for environmental risk factors Description of database for environmental risk factors D1.2 Final report on successfully performed communication, dissemination, exploitation activities. Final report on successfully performed communication dissemination exploitation activitiesDelay due to COVID19 due date to be moved to M66 We were making steady progress with milestones and deliverables from WP2 MS 23 MS 24 D23 and WP3 MS 3235 D32 which were delayed previously as reported in RP2 also indicated in this table below Due to the sudden reduction in lab capacities as the COVID19 crisis evolved some parts of the final analyses on the TMAs for WP2 D23 and about 1000 samples still remain to be sequenced at CNAG MS34 consequently on MS35 and D32 which was otherwise expected to be completed by midApril 2020 With the requested extension we will be able to complete our target of generating new genomic information based on IHCISH panels on 25873 tumours and targeted sequencing on a subset of 10000 tumours that will inform risk and prognosis modelling of breast cancer Additionally we can then include these analyses in our manuscripts which will play a key role in informing the scientific community about our results D4.3 Description of genotyping database Description of genotyping database D8.1 Report on current public health and policy discourses on personalised breast cancer prevention Report on current public health and policy discourses on personalised breast cancer prevention D8.3 Final report on personalised breast cancer prevention aimed at public health professionals and policy makers Final report on personalised breast cancer prevention aimed at public health professionals and policy makers Websites, patent fillings, videos etc. (4) D7.1 Web-tool (in English) that predicts overall breast cancer risk and the risks for breast cancer subtypes Webtool in English that predicts overall breast cancer risk and the risks for breast cancer subtypes D1.1. Website for internal and external communication Website for internal and external communication Note dissemination level: some parts of the website will only be for project members (CO) D7.3 Translated versions of the risk prediction and prognosis tools in other languages Translated versions of the risk prediction and prognosis tools in other languages D7.2 Web-tool (in English) that predicts survival after a breast cancer diagnosis Webtool in English that predicts survival after a breast cancer diagnosis Publikacje Peer reviewed articles (54) Identification of Women at High Risk of Breast Cancer Who Need Supplemental Screening Autorzy: Mikael Eriksson, Kamila Czene, Fredrik Strand, Sophia Zackrisson, Peter Lindholm, Kristina Lång, Daniel Förnvik, Hanna Sartor, Nasim Mavaddat, Doug Easton, Per Hall Opublikowane w: Radiology, Issue 297/2, 2020, Page(s) 327-333, ISSN 0033-8419 Wydawca: Radiological Society of North America DOI: 10.1148/radiol.2020201620 Predictors of mammographic microcalcifications Autorzy: Shadi Azam, Mikael Eriksson, Arvid Sjölander, Marike Gabrielson, Roxanna Hellgren, Kamila Czene, Per Hall Opublikowane w: International Journal of Cancer, Issue 148/5, 2021, Page(s) 1132-1143, ISSN 0020-7136 Wydawca: John Wiley & Sons Inc. DOI: 10.1002/ijc.33302 CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers Autorzy: Nichola Johnson, Sarah Maguire, Anna Morra, Pooja Middha Kapoor, Katarzyna Tomczyk, Michael E. Jones, Minouk J. Schoemaker, Clare Gilham, Manjeet K. Bolla, Qin Wang, Joe Dennis, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Caroline Baynes, Laura E. Beane Freeman, Matthias W. Beckmann, Javier Benitez, Marina Opublikowane w: British Journal of Cancer, Issue 124/4, 2021, Page(s) 842-854, ISSN 0007-0920 Wydawca: Nature Publishing Group DOI: 10.1038/s41416-020-01185-w Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry Autorzy: Parichoy Pal Choudhury, Mark N. Brook, Amber N. Hurson, Andrew Lee, Charlotta V. Mulder, Penny Coulson, Minouk J. Schoemaker, Michael E. Jones, Anthony J. Swerdlow, Nilanjan Chatterjee, Antonis C. Antoniou, Montserrat Garcia-Closas Opublikowane w: Breast Cancer Research, Issue 23/1, 2021, ISSN 1465-542X Wydawca: BMC Springer Nature DOI: 10.1186/s13058-021-01399-7 Personalized early detection and prevention of breast cancer: ENVISION consensus statement Autorzy: Nora Pashayan, Antonis C. Antoniou, Urska Ivanus, Laura J. Esserman, Douglas F. Easton, David French, Gaby Sroczynski, Per Hall, Jack Cuzick, D. Gareth Evans, Jacques Simard, Montserrat Garcia-Closas, Rita Schmutzler, Odette Wegwarth, Paul Pharoah, Sowmiya Moorthie, Sandrine De Montgolfier, Camille Baron, Zdenko Herceg, Clare Turnbull, Corinne Balleyguier, Paolo Giorgi Rossi, Jelle Wesseling, Davi Opublikowane w: Nature Reviews Clinical Oncology, Issue 17/11, 2020, Page(s) 687-705, ISSN 1759-4774 Wydawca: Nature Publishing Group DOI: 10.1038/s41571-020-0388-9 CanRisk Tool—A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants Autorzy: Tim Carver, Simon Hartley, Andrew Lee, Alex P. Cunningham, Stephanie Archer, Chantal Babb de Villiers, Jonathan Roberts, Rod Ruston, Fiona M. Walter, Marc Tischkowitz, Douglas F. Easton, Antonis C. Antoniou Opublikowane w: Cancer Epidemiology Biomarkers & Prevention, Issue 30/3, 2021, Page(s) 469-473, ISSN 1055-9965 Wydawca: American Association for Cancer Research DOI: 10.1158/1055-9965.epi-20-1319 Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk Autorzy: Pooja Middha Kapoor, Nasim Mavaddat, Parichoy Pal Choudhury, Amber N Wilcox, Sara Lindström, Sabine Behrens, Kyriaki Michailidou, Joe Dennis, Manjeet K Bolla, Qin Wang, Audrey Jung, Zomoroda Abu-Ful, Thomas Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Paul L Auer, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Lesl Opublikowane w: JNCI: Journal of the National Cancer Institute, Issue 113/3, 2020, Page(s) 329-337, ISSN 0027-8874 Wydawca: Oxford University Press DOI: 10.1093/jnci/djaa056 Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries Autorzy: Amber N Hurson, Parichoy Pal Choudhury, Chi Gao, Anika Hüsing, Mikael Eriksson, Min Shi, Michael E Jones, D Gareth R Evans, Roger L Milne, Mia M Gaudet, Celine M Vachon, Daniel I Chasman, Douglas F Easton, Marjanka K Schmidt, Peter Kraft, Montserrat Garcia-Closas, Nilanjan Chatterjee, Christopher G Scott, Brian D Carter, Kara Martin, Elaine F Harkness, Mark N Brook, Thomas U Ahearn, Nasim Mavadda Opublikowane w: International Journal of Epidemiology, 2021, ISSN 0300-5771 Wydawca: Oxford University Press DOI: 10.1093/ije/dyab036 Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women Autorzy: Leila Dorling, Sara Carvalho, Jamie Allen, Anna González-Neira, Craig Luccarini, Cecilia Wahlström, Karen A. Pooley, Michael T. Parsons, Cristina Fortuno, Qin Wang, Manjeet K. Bolla, Joe Dennis, Renske Keeman, M. Rosario Alonso, Nuria Álvarez, Belen Herraez, Victoria Fernandez, Rocio Núñez-Torres, Ana Osorio, Jeanette Valcich, Minerva Li, Therese Törngren, Patricia A. Harrington, Caroline Ba Opublikowane w: New England Journal of Medicine, Issue 384/5, 2021, Page(s) 428-439, ISSN 0028-4793 Wydawca: Massachusetts Medical Society DOI: 10.1056/nejmoa1913948 Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk Autorzy: Iris Kramer, Maartje J. Hooning, Nasim Mavaddat, Michael Hauptmann, Renske Keeman, Ewout W. Steyerberg, Daniele Giardiello, Antonis C. Antoniou, Paul D.P. Pharoah, Sander Canisius, Zumuruda Abu-Ful, Irene L. Andrulis, Hoda Anton-Culver, Kristan J. Aronson, Annelie Augustinsson, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Natalia V. Bogdanova, Stig E. Boje Opublikowane w: The American Journal of Human Genetics, Issue 107/5, 2020, Page(s) 837-848, ISSN 0002-9297 Wydawca: University of Chicago Press DOI: 10.1016/j.ajhg.2020.09.001 Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium Autorzy: Myrto Barrdahl, Anja Rudolph, John L. Hopper, Melissa C. Southey, Annegien Broeks, Peter A. Fasching, Matthias W. Beckmann, Manuela Gago-Dominguez, J. Esteban Castelao, Pascal Guénel, Thérèse Truong, Stig E. Bojesen, Susan M. Gapstur, Mia M. Gaudet, Hermann Brenner, Volker Arndt, Hiltrud Brauch, Ute Hamann, Arto Mannermaa, Diether Lambrechts, Lynn Jongen, Dieter Flesch-Janys, Kathrin Thoene, Fe Opublikowane w: International Journal of Cancer, Issue 141/9, 2017, Page(s) 1830-1840, ISSN 0020-7136 Wydawca: John Wiley & Sons Inc. DOI: 10.1002/ijc.30859 Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium Autorzy: Anja Rudolph, Minsun Song, Mark N Brook, Roger L Milne, Nasim Mavaddat, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Amber N Wilcox, John L Hopper, Melissa C Southey, Renske Keeman, Peter A Fasching, Matthias W Beckmann, Manuela Gago-Dominguez, Jose E Castelao, Pascal Guénel, Thérèse Truong, Stig E Bojesen, Henrik Flyger, Hermann Brenner, Volker Arndt, Hiltrud Brauch, Thomas Brü Opublikowane w: International Journal of Epidemiology, Issue 47/2, 2018, Page(s) 526-536, ISSN 0300-5771 Wydawca: Oxford University Press DOI: 10.1093/ije/dyx242 A comprehensive tool for measuring mammographic density changes over time Autorzy: Mikael Eriksson, Jingmei Li, Karin Leifland, Kamila Czene, Per Hall Opublikowane w: Breast Cancer Research and Treatment, Issue 169/2, 2018, Page(s) 371-379, ISSN 0167-6806 Wydawca: Kluwer Academic Publishers DOI: 10.1007/s10549-018-4690-5 Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries Autorzy: Anne Brédart, Jean-Luc Kop, Antonis C. Antoniou, Alex P. Cunningham, Antoine De Pauw, Marc Tischkowitz, Hans Ehrencrona, Sylvie Dolbeault, Léonore Robieux, Kerstin Rhiem, Douglas F. Easton, Peter Devilee, Dominique Stoppa-Lyonnet, Rita Schmutlzer Opublikowane w: Familial Cancer, Issue 17/1, 2018, Page(s) 31-41, ISSN 1389-9600 Wydawca: Kluwer Academic Publishers DOI: 10.1007/s10689-017-0014-x A clinical model for identifying the short-term risk of breast cancer Autorzy: Mikael Eriksson, Kamila Czene, Yudi Pawitan, Karin Leifland, Hatef Darabi, Per Hall Opublikowane w: Breast Cancer Research, Issue 19/1, 2017, ISSN 1465-542X Wydawca: BMC DOI: 10.1186/s13058-017-0820-y Evaluating clinician acceptability of the prototype CanRisk tool for predicting risk of breast and ovarian cancer: A multi-methods study Autorzy: Stephanie Archer, Chantal Babb de Villiers, Fiona Scheibl, Tim Carver, Simon Hartley, Andrew Lee, Alex P. Cunningham, Douglas F. Easton, Jennifer G. McIntosh, Jon Emery, Marc Tischkowitz, Antonis C. Antoniou, Fiona M. Walter Opublikowane w: PLOS ONE, Issue 15/3, 2020, Page(s) e0229999, ISSN 1932-6203 Wydawca: Public Library of Science DOI: 10.1371/journal.pone.0229999 Transcriptome‐wide association study of breast cancer risk by estrogen‐receptor status Autorzy: Helian Feng, Alexander Gusev, Bogdan Pasaniuc, Lang Wu, Jirong Long, Zomoroda Abu‐full, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton‐Culver, Antonis C. Antoniou, Adalgeir Arason, Volker Arndt, Kristan J. Aronson, Banu K. Arun, Ella Asseryanis, Paul L. Auer, Jacopo Azzollini, Judith Balmaña, Rosa B. Barkardottir, Daniel R. Barnes, Daniel Barrowdale, Matthias W. Beckmann, Sabine Behrens, Opublikowane w: Genetic Epidemiology, 2020, ISSN 0741-0395 Wydawca: John Wiley & Sons Inc. DOI: 10.1002/gepi.22288 Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium Autorzy: Pooja Middha Kapoor, Sara Lindström, Sabine Behrens, Xiaoliang Wang, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Alison M Dunning, Paul D P Pharoah, Marjanka K Schmidt, Peter Kraft, Montserrat García-Closas, Douglas F Easton, Roger L Milne, Jenny Chang-Claude Opublikowane w: International Journal of Epidemiology, Issue 49/1, 2019, Page(s) 216-232, ISSN 0300-5771 Wydawca: Oxford University Press DOI: 10.1093/ije/dyz193 A network analysis to identify mediators of germline-driven differences in breast cancer prognosis Autorzy: Maria Escala-Garcia, Jean Abraham, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Alan Ashworth, Paul L. Auer, Päivi Auvinen, Matthias W. Beckmann, Jonathan Beesley, Sabine Behrens, Javier Benitez, Marina Bermisheva, Carl Blomqvist, William Blot, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Anne-Lise Børresen-Dale, Hiltrud Brauch, Hermann Brenner, Sara Y. Brucker, Barbara Burwin Opublikowane w: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723 Wydawca: Nature Publishing Group DOI: 10.1038/s41467-019-14100-6 Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes Autorzy: Laura Fachal, Hugues Aschard, Jonathan Beesley, Daniel R. Barnes, Jamie Allen, Siddhartha Kar, Karen A. Pooley, Joe Dennis, Kyriaki Michailidou, Constance Turman, Penny Soucy, Audrey Lemaçon, Michael Lush, Jonathan P. Tyrer, Maya Ghoussaini, Mahdi Moradi Marjaneh, Xia Jiang, Simona Agata, Kristiina Aittomäki, M. Rosario Alonso, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Adalge Opublikowane w: Nature Genetics, Issue 52/1, 2020, Page(s) 56-73, ISSN 1061-4036 Wydawca: Nature Publishing Group DOI: 10.1038/s41588-019-0537-1 Prediction and clinical utility of a contralateral breast cancer risk model Autorzy: Daniele Giardiello, Ewout W. Steyerberg, Michael Hauptmann, Muriel A. Adank, Delal Akdeniz, Carl Blomqvist, Stig E. Bojesen, Manjeet K. Bolla, Mariël Brinkhuis, Jenny Chang-Claude, Kamila Czene, Peter Devilee, Alison M. Dunning, Douglas F. Easton, Diana M. Eccles, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Montserrat García-Closas, Lothar Haeberle, Christopher A. Haiman, Per Hall, Ute Ha Opublikowane w: Breast Cancer Research, Issue 21/1, 2019, ISSN 1465-542X Wydawca: BMC DOI: 10.1186/s13058-019-1221-1 The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer Autorzy: Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna I. Kiiski, Taru A. Muranen, Daniel R. Barnes, Joe Dennis, Kyriaki Michailidou, Manjeet K. Bolla, Goska Leslie, Cora M. Aalfs, Muriel A. Adank, Julian Adlard, Simona Agata, Karen Cadoo, Bjarni A. Agnarsson, Thomas Ahearn, Kristiina Aittomäki, Christine B. Ambrosone, Lesley Andrews, Hoda Anton Opublikowane w: npj Breast Cancer, Issue 5/1, 2019, ISSN 2374-4677 Wydawca: Nature Partner Journal Series DOI: 10.1038/s41523-019-0127-5 Two truncating variants in FANCC and breast cancer risk Autorzy: Thilo Dörk, Paolo Peterlongo, Arto Mannermaa, Manjeet K. Bolla, Qin Wang, Joe Dennis, Thomas Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Laura E. Beane Freeman, Matthias W. Beckmann, Alicia Beeghly-Fadiel, Sabine Behrens, Marina Bermisheva, Carl Blomqvist, Natalia V. Bogdanova, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burw Opublikowane w: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322 Wydawca: Nature Publishing Group DOI: 10.1038/s41598-019-48804-y The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium Autorzy: Tomotaka Ugai, Roger L. Milne, Hidemi Ito, Kristan J. Aronson, Manjeet K. Bolla, Tsun Chan, Ching W. Chan, Ji-Yeob Choi, Don M. Conroy, Joe Dennis, Alison M. Dunning, Douglas F. Easton, Valerie Gaborieau, Anna Gonzalez-Neira, Mikael Hartman, Catherine S. Healey, Motoki Iwasaki, Esther M. John, Daehee Kang, Sung-Won Kim, Ava Kwong, Artitaya Lophatananon, Kyriaki Michailidou, Nur Aishah Mohd Taib, K Opublikowane w: Molecular Genetics & Genomic Medicine, Issue 7/6, 2019, Page(s) e707, ISSN 2324-9269 Wydawca: Wiley DOI: 10.1002/mgg3.707 Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk Autorzy: Celine M. Vachon, Christopher G. Scott, Rulla M. Tamimi, Deborah J. Thompson, Peter A. Fasching, Jennifer Stone, Melissa C. Southey, Stacey Winham, Sara Lindström, Jenna Lilyquist, Graham G. Giles, Roger L. Milne, Robert J. MacInnis, Laura Baglietto, Jingmei Li, Kamila Czene, Manjeet K. Bolla, Qin Wang, Joe Dennis, Lothar Haeberle, Mikael Eriksson, Peter Kraft, Robert Luben, Nick Wareham, Janet E Opublikowane w: Breast Cancer Research, Issue 21/1, 2019, ISSN 1465-542X Wydawca: BMC part of Springer Nature DOI: 10.1186/s13058-019-1138-8 Genetically Predicted Levels of DNA Methylation Biomarkers and Breast Cancer Risk: Data From 228 951 Women of European Descent Autorzy: Yaohua Yang, Lang Wu, Xiao-Ou Shu, Qiuyin Cai, Xiang Shu, Bingshan Li, Xingyi Guo, Fei Ye, Kyriaki Michailidou, Manjeet K Bolla, Qin Wang, Joe Dennis, Irene L Andrulis, Hermann Brenner, Georgia Chenevix-Trench, Daniele Campa, Jose E Castelao, Manuela Gago-Dominguez, Thilo Dörk, Antoinette Hollestelle, Artitaya Lophatananon, Kenneth Muir, Susan L Neuhausen, Håkan Olsson, Dale P Sandler, Jacques S Opublikowane w: JNCI: Journal of the National Cancer Institute, Issue 112/3, 2019, Page(s) 295-304, ISSN 0027-8874 Wydawca: Oxford University Press DOI: 10.1093/jnci/djz109 Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer Autorzy: Manuel A. Ferreira, Eric R. Gamazon, Fares Al-Ejeh, Kristiina Aittomäki, Irene L. Andrulis, Hoda Anton-Culver, Adalgeir Arason, Volker Arndt, Kristan J. Aronson, Banu K. Arun, Ella Asseryanis, Jacopo Azzollini, Judith Balmaña, Daniel R. Barnes, Daniel Barrowdale, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Katarzyna Białkowska, Carl Blomqvist, Natalia V. Bogdanova, Opublikowane w: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Wydawca: Nature Publishing Group DOI: 10.1038/s41467-018-08053-5 Genome-wide association study of germline variants and breast cancer-specific mortality Autorzy: Maria Escala-Garcia, Qi Guo, Thilo Dörk, Sander Canisius, Renske Keeman, Joe Dennis, Jonathan Beesley, Julie Lecarpentier, Manjeet K. Bolla, Qin Wang, Jean Abraham, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Paul L. Auer, Matthias W. Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, Leslie Bernstein, Carl Blomqvist, Bram Boeckx, Stig E. Bojesen, Bernardo Bonanni, Anne-Lise Bø Opublikowane w: British Journal of Cancer, Issue 120/6, 2019, Page(s) 647-657, ISSN 0007-0920 Wydawca: Nature Publishing Group DOI: 10.1038/s41416-019-0393-x Shared heritability and functional enrichment across six solid cancers Autorzy: Xia Jiang, Hilary K. Finucane, Fredrick R. Schumacher, Stephanie L. Schmit, Jonathan P. Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B. Kuchenbaecker, Joe Dennis, David V. Conti, Graham Casey, Mia M. Gaudet, Jeroen R. Huyghe, Demetrius Albanes, Melinda C. Aldrich, Angeline S. Andrew, Irene L. Andrulis, Hoda Anton-Culver, Antonis C. Antoniou, Natalia N. Antonenkova, Susanne M. Opublikowane w: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Wydawca: Nature Publishing Group DOI: 10.1038/s41467-018-08054-4 BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors Autorzy: Andrew Lee, Nasim Mavaddat, Amber N. Wilcox, Alex P. Cunningham, Tim Carver, Simon Hartley, Chantal Babb de Villiers, Angel Izquierdo, Jacques Simard, Marjanka K. Schmidt, Fiona M. Walter, Nilanjan Chatterjee, Montserrat Garcia-Closas, Marc Tischkowitz, Paul Pharoah, Douglas F. Easton, Antonis C. Antoniou Opublikowane w: Genetics in Medicine, Issue 21/8, 2019, Page(s) 1708-1718, ISSN 1098-3600 Wydawca: Lippincott Williams & Wilkins Ltd. DOI: 10.1038/s41436-018-0406-9 Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes Autorzy: Nasim Mavaddat, Kyriaki Michailidou, Joe Dennis, Michael Lush, Laura Fachal, Andrew Lee, Jonathan P. Tyrer, Ting-Huei Chen, Qin Wang, Manjeet K. Bolla, Xin Yang, Muriel A. Adank, Thomas Ahearn, Kristiina Aittomäki, Jamie Allen, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Paul L. Auer, Päivi Auvinen, Myrto Barrdahl, Laura E. Beane Freeman, Matth Opublikowane w: The American Journal of Human Genetics, Issue 104/1, 2019, Page(s) 21-34, ISSN 0002-9297 Wydawca: University of Chicago Press DOI: 10.1016/j.ajhg.2018.11.002 A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer Autorzy: Lang Wu, Wei Shi, Jirong Long, Xingyi Guo, Kyriaki Michailidou, Jonathan Beesley, Manjeet K. Bolla, Xiao-Ou Shu, Yingchang Lu, Qiuyin Cai, Fares Al-Ejeh, Esdy Rozali, Qin Wang, Joe Dennis, Bingshan Li, Chenjie Zeng, Helian Feng, Alexander Gusev, Richard T. Barfield, Irene L. Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J. Aronson, Paul L. Auer, Myrto Barrdahl, Caroline Baynes, Matthias W. Be Opublikowane w: Nature Genetics, Issue 50/7, 2018, Page(s) 968-978, ISSN 1061-4036 Wydawca: Nature Publishing Group DOI: 10.1038/s41588-018-0132-x E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium Autorzy: Hisani N. Horne, Hannah Oh, Mark E. Sherman, Maya Palakal, Stephen M. Hewitt, Marjanka K. Schmidt, Roger L. Milne, David Hardisson, Javier Benitez, Carl Blomqvist, Manjeet K. Bolla, Hermann Brenner, Jenny Chang-Claude, Renata Cora, Fergus J. Couch, Katarina Cuk, Peter Devilee, Douglas F. Easton, Diana M. Eccles, Ursula Eilber, Jaana M. Hartikainen, Päivi Heikkilä, Bernd Holleczek, Maartje J. 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