Elucidating Pathways of Steatohepatitis

Rezultaty

Detailed dissemination plan
Final reports summarising recruitment into the EPoS database, biobanked samples availability, and longitudinal outcome studies
Report on data management plan for the EPoS project
Project Handbook
Risk assessment procedure

Publikacje

Relationship Among Fatty Liver, Specific and Multiple‐Site Atherosclerosis, and 10‐Year Framingham Score

Autorzy: Raluca Pais, Alban Redheuil, Philippe Cluzel, Vlad Ratziu, Philippe Giral
Opublikowane w: Hepatology, Numer 69/4, 2019, Strona(/y) 1453-1463, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.30223

Autorzy: Yvonne Huber, Marie Boyle, Kate Hallsworth, Dina Tiniakos, Beate K. Straub, Christian Labenz, Christian Ruckes, Peter R. Galle, Manuel Romero-Gómez, Quentin M. Anstee, Jörn M. Schattenberg
Opublikowane w: Clinical Gastroenterology and Hepatology, Numer 17/10, 2019, Strona(/y) 2085-2092.e1, ISSN 1542-3565
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.cgh.2018.12.016

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

Autorzy: Judith Aron-Wisnewsky, Chloé Vigliotti, Julia Witjes, Phuong Le, Adriaan G. Holleboom, Joanne Verheij, Max Nieuwdorp, Karine Clément
Opublikowane w: Nature Reviews Gastroenterology & Hepatology, Numer 17/5, 2020, Strona(/y) 279-297, ISSN 1759-5045
Wydawca: Nature Publishing Group
DOI: 10.1038/s41575-020-0269-9

Usefulness of the index of NASH - ION for the diagnosis of steatohepatitis in patients with non-alcoholic fatty liver: An external validation study

Autorzy: Ramy Younes, Chiara Rosso, Salvatore Petta, Monica Cucco, Milena Marietti, Gian Paolo Caviglia, Alessia Ciancio, Maria Lorena Abate, Carlo Cammà, Antonina Smedile, Antonio Craxì, Giorgio Maria Saracco, Elisabetta Bugianesi
Opublikowane w: Liver International, Numer 38/4, 2018, Strona(/y) 715-723, ISSN 1478-3223
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/liv.13612

Predictors of advanced fibrosis in non-cirrhotic non-alcoholic fatty liver disease in Germany

Autorzy: Christian Labenz, Yvonne Huber, Eva Kalliga, Michael Nagel, Christian Ruckes, Beate K. Straub, Peter R. Galle, Marcus-Alexander Wörns, Quentin M. Anstee, Detlef Schuppan, Jörn M. Schattenberg
Opublikowane w: Alimentary Pharmacology & Therapeutics, Numer 48/10, 2018, Strona(/y) 1109-1116, ISSN 0269-2813
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/apt.14976

Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort☆

Autorzy: Quentin M. Anstee, Rebecca Darlay, Simon Cockell, Marica Meroni, Olivier Govaere, Dina Tiniakos, Alastair D. Burt, Pierre Bedossa, Jeremy Palmer, Yang-Lin Liu, Guruprasad P. Aithal, Michael Allison, Hannele Yki-Järvinen, Michele Vacca, Jean-Francois Dufour, Pietro Invernizzi, Daniele Prati, Mattias Ekstedt, Stergios Kechagias, Sven Francque, Salvatore Petta, Elisabetta Bugianesi, Karine Clement,
Opublikowane w: Journal of Hepatology, Numer 73/3, 2020, Strona(/y) 505-515, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2020.04.003

Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma

Autorzy: Zoe Hall, Davide Chiarugi, Evelina Charidemou, Jack Leslie, Emma Scott, Luca Pellegrinet, Michael Allison, Gabriele Mocciaro, Quentin M. Anstee, Gerard I. Evan, Matthew Hoare, Antonio Vidal‐Puig, Fiona Oakley, Michele Vacca, Julian L. Griffin
Opublikowane w: Hepatology, Numer 73/3, 2021, Strona(/y) 1028-1044, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.31391

Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach?

Autorzy: Ramy Younes, Olivier Govaere, Salvatore Petta, Luca Miele, Dina Tiniakos, Alastair Burt, Ezio David, Fabio Maria Vecchio, Marco Maggioni, Daniela Cabibi, Duncan McLeod, Maria Jesus Pareja, Anna Ludovica Fracanzani, Rocio Aller, Chiara Rosso, Javier Ampuero, Rocío Gallego-Durán, Angelo Armandi, Gian Paolo Caviglia, Marco Y W Zaki, Antonio Liguori, Paolo Francione, Grazia Pennisi, Antonio Grieco,
Opublikowane w: Gut, 2021, Strona(/y) gutjnl-2020-322564, ISSN 0017-5749
Wydawca: BMJ Publishing Group
DOI: 10.1136/gutjnl-2020-322564

Clinical implications of hepatic progenitor cell activation in non-alcoholic fatty liver disease

Autorzy: Ramy Younes, Rachel Burgoyne, Dina Tiniakos, Olivier Govaere
Opublikowane w: Hepatoma Research, Numer 2021, 2021, ISSN 2454-2520
Wydawca: -
DOI: 10.20517/2394-5079.2020.119

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling

Autorzy: Ching Jian, Panu Luukkonen, Hannele Yki-Järvinen, Anne Salonen, Katri Korpela
Opublikowane w: PLOS ONE, Numer 15/1, 2020, Strona(/y) e0227285, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0227285

Elevated serum ceramides are linked with obesity-associated gut dysbiosis and impaired glucose metabolism

Autorzy: Brandon D. Kayser, Edi Prifti, Marie Lhomme, Eugeni Belda, Maria-Carlota Dao, Judith Aron-Wisnewsky, Anatol Kontush, Jean-Daniel Zucker, Salwa W. Rizkalla, Isabelle Dugail, Karine Clément
Opublikowane w: Metabolomics, Numer 15/11, 2019, ISSN 1573-3882
Wydawca: Springer Verlag
DOI: 10.1007/s11306-019-1596-0

Interplay between metabolic derangement, hepatic fibrogenesis and macrophage activation in non-diabetic patients with non-alcoholic fatty liver disease

Autorzy: C. Rosso, R. Younes, D.J. Leeming, R. Surabattula, G.P. Caviglia, M. Gaggini, A. Armandi, A. Olivero, M.L. Abate, A. Gastaldelli, D. Schuppan, E. Bugianesi
Opublikowane w: Digestive and Liver Disease, Numer 52, 2020, Strona(/y) e10, ISSN 1590-8658
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.dld.2019.12.025

Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

Autorzy: Tuulia Hyötyläinen, Livnat Jerby, Elina M. Petäjä, Ismo Mattila, Sirkku Jäntti, Petri Auvinen, Amalia Gastaldelli, Hannele Yki-Järvinen, Eytan Ruppin, Matej Orešič
Opublikowane w: Nature Communications, Numer 7, 2016, Strona(/y) 8994, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms9994

Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance

Autorzy: Hannele Yki-Järvinen
Opublikowane w: Nutrients, Numer 7/11, 2015, Strona(/y) 9127-9138, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu7115454

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

Autorzy: Zobair Younossi, Quentin M. Anstee, Milena Marietti, Timothy Hardy, Linda Henry, Mohammed Eslam, Jacob George, Elisabetta Bugianesi
Opublikowane w: Nature Reviews Gastroenterology & Hepatology, Numer 15/1, 2017, Strona(/y) 11-20, ISSN 1759-5045
Wydawca: Nature Publishing Group
DOI: 10.1038/nrgastro.2017.109

Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD

Autorzy: Elina M. Petäjä, You Zhou, Marika Havana, Antti Hakkarainen, Nina Lundbom, Jarkko Ihalainen, Hannele Yki-Järvinen
Opublikowane w: Scientific Reports, Numer 6/1, 2016, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep24740

Fibrogenesis assessed by serological type III collagen formation identifies patients with progressive liver fibrosis and responders to a potential antifibrotic therapy

Autorzy: Morten A. Karsdal, Kim Henriksen, Mette Juul Nielsen, Inger Byrjalsen, Diana J. Leeming, Stephen Gardner, Zachary Goodman, Keyur Patel, Aleksander Krag, Claus Christiansen, Detlef Schuppan
Opublikowane w: American Journal of Physiology-Gastrointestinal and Liver Physiology, Numer 311/6, 2016, Strona(/y) G1009-G1017, ISSN 0193-1857
Wydawca: American Physiological Society
DOI: 10.1152/ajpgi.00283.2016

MBOAT7 rs641738 variant and hepatocellular carcinoma in non-cirrhotic individuals

Autorzy: Benedetta Donati, Paola Dongiovanni, Stefano Romeo, Marica Meroni, Misti McCain, Luca Miele, Salvatore Petta, Silvia Maier, Chiara Rosso, Laura De Luca, Ester Vanni, Stefania Grimaudo, Renato Romagnoli, Fabio Colli, Flaminia Ferri, Rosellina Margherita Mancina, Paula Iruzubieta, Antonio Craxi, Anna Ludovica Fracanzani, Antonio Grieco, Stefano Ginanni Corradini, Alessio Aghemo, Massimo Colombo, Gio
Opublikowane w: Scientific Reports, Numer 7/1, 2017, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-017-04991-0

NAFLD: PNPLA3 and obesity: a synergistic relationship in NAFLD

Autorzy: Jake P. Mann, Quentin M. Anstee
Opublikowane w: Nature Reviews Gastroenterology & Hepatology, Numer 14/9, 2017, Strona(/y) 506-507, ISSN 1759-5045
Wydawca: Nature Publishing Group
DOI: 10.1038/nrgastro.2017.74

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis

Autorzy: Stuart McPherson, Tim Hardy, Jean-Francois Dufour, Salvatore Petta, Manuel Romero-Gomez, Mike Allison, Claudia P Oliveira, Sven Francque, Luc Van Gaal, Jörn M Schattenberg, Dina Tiniakos, Alastair Burt, Elisabetta Bugianesi, Vlad Ratziu, Christopher P Day, Quentin M Anstee
Opublikowane w: The American Journal of Gastroenterology, Numer 112/5, 2016, Strona(/y) 740-751, ISSN 0002-9270
Wydawca: Blackwell Publishing Inc.
DOI: 10.1038/ajg.2016.453

Serum lipidomics reveals early differential effects of gastric bypass compared with banding on phospholipids and sphingolipids independent of differences in weight loss

Autorzy: B D Kayser, M Lhomme, M C Dao, F Ichou, J-L Bouillot, E Prifti, A Kontush, J-M Chevallier, J Aron-Wisnewsky, I Dugail, K Clément
Opublikowane w: International Journal of Obesity, Numer 41/6, 2017, Strona(/y) 917-925, ISSN 0307-0565
Wydawca: Nature Publishing Group
DOI: 10.1038/ijo.2017.63

Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD—A Systematic Review

Autorzy: Elina Petäjä, Hannele Yki-Järvinen
Opublikowane w: International Journal of Molecular Sciences, Numer 17/5, 2016, Strona(/y) 633, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms17050633

Glucose kinetics

Autorzy: Amalia Gastaldelli, Melania Gaggini, Ralph DeFronzo
Opublikowane w: Current Opinion in Clinical Nutrition and Metabolic Care, Numer 20/4, 2017, Strona(/y) 300-309, ISSN 1363-1950
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/MCO.0000000000000384

The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans

Autorzy: Panu K. Luukkonen, You Zhou, Tuulia Hyötyläinen, Marja Leivonen, Johanna Arola, Marju Orho-Melander, Matej Orešič, Hannele Yki-Järvinen
Opublikowane w: Journal of Hepatology, Numer 65/6, 2016, Strona(/y) 1263-1265, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2016.07.045

Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans

Autorzy: Panu K. Luukkonen, You Zhou, Elina Isokuortti, Marja Leivonen, Anne Juuti, Antti Hakkarainen, Marju Orho-Melander, Nina Lundbom, Vesa M. Olkkonen, Riitta Lassila, Hannele Yki-Järvinen, Susanna Lallukka
Opublikowane w: Thrombosis and Haemostasis, Numer 117/02, 2017, Strona(/y) 286-294, ISSN 0340-6245
Wydawca: Schattauer
DOI: 10.1160/TH16-09-0716

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

Autorzy: Leon A Adams, Quentin M Anstee, Herbert Tilg, Giovanni Targher
Opublikowane w: Gut, Numer 66/6, 2017, Strona(/y) 1138-1153, ISSN 0017-5749
Wydawca: BMJ Publishing Group
DOI: 10.1136/gutjnl-2017-313884

Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease

Autorzy: Zoe Hall, Nicholas J. Bond, Tom Ashmore, Francis Sanders, Zsuzsanna Ament, Xinzhu Wang, Andrew J. Murray, Elena Bellafante, Sam Virtue, Antonio Vidal-Puig, Michael Allison, Susan E. Davies, Albert Koulman, Michele Vacca, Julian L. Griffin
Opublikowane w: Hepatology, Numer 65/4, 2017, Strona(/y) 1165-1180, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.28953

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study

Autorzy: Elina Isokuortti, You Zhou, Markku Peltonen, Elisabetta Bugianesi, Karine Clement, Dominique Bonnefont-Rousselot, Jean-Marc Lacorte, Amalia Gastaldelli, Detlef Schuppan, Jörn M. Schattenberg, Antti Hakkarainen, Nina Lundbom, Pekka Jousilahti, Satu Männistö, Sirkka Keinänen-Kiukaanniemi, Juha Saltevo, Quentin M. Anstee, Hannele Yki-Järvinen
Opublikowane w: Diabetologia, Numer 60/10, 2017, Strona(/y) 1873-1882, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-017-4340-1

Role of Adipose Tissue Insulin Resistance in the Natural History of Type 2 Diabetes: Results From the San Antonio Metabolism Study

Autorzy: Amalia Gastaldelli, Melania Gaggini, Ralph A. DeFronzo
Opublikowane w: Diabetes, Numer 66/4, 2017, Strona(/y) 815-822, ISSN 0012-1797
Wydawca: American Diabetes Association
DOI: 10.2337/db16-1167

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD

Autorzy: Panu K. Luukkonen, You Zhou, P.A. Nidhina Haridas, Om P. Dwivedi, Tuulia Hyötyläinen, Ashfaq Ali, Anne Juuti, Marja Leivonen, Taru Tukiainen, Linda Ahonen, Emma Scott, Jeremy M. Palmer, Johanna Arola, Marju Orho-Melander, Petter Vikman, Quentin M. Anstee, Vesa M. Olkkonen, Matej Orešič, Leif Groop, Hannele Yki-Järvinen
Opublikowane w: Journal of Hepatology, Numer 67/1, 2017, Strona(/y) 128-136, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2017.02.014

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Autorzy: Shabnam Shalapour, Xue-Jia Lin, Ingmar N. Bastian, John Brain, Alastair D. Burt, Alexander A. Aksenov, Alison F. Vrbanac, Weihua Li, Andres Perkins, Takaji Matsutani, Zhenyu Zhong, Debanjan Dhar, Jose A. Navas-Molina, Jun Xu, Rohit Loomba, Michael Downes, Ruth T. Yu, Ronald M. Evans, Pieter C. Dorrestein, Rob Knight, Christopher Benner, Quentin M. Anstee, Michael Karin
Opublikowane w: Nature, Numer 551/7680, 2017, Strona(/y) 340-345, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/nature24302

Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance

Autorzy: Melania Gaggini, Fabrizia Carli, Chiara Rosso, Emma Buzzigoli, Milena Marietti, Veronica Della Latta, Demetrio Ciociaro, Maria Lorena Abate, Roberto Gambino, Maurizio Cassader, Elisabetta Bugianesi, Amalia Gastaldelli
Opublikowane w: Hepatology, Numer 67/1, 2018, Strona(/y) 145-158, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.29465

The good and the bad collagens of fibrosis – Their role in signaling and organ function

Autorzy: M.A. Karsdal, S.H. Nielsen, D.J. Leeming, L.L. Langholm, M.J. Nielsen, T. Manon-Jensen, A. Siebuhr, N.S. Gudmann, S. Rønnow, J.M. Sand, S.J. Daniels, J.H. Mortensen, D. Schuppan
Opublikowane w: Advanced Drug Delivery Reviews, Numer 121, 2017, Strona(/y) 43-56, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2017.07.014

Should we undertake surveillance for HCC in patients with NAFLD?

Autorzy: Ramy Younes, Elisabetta Bugianesi
Opublikowane w: Journal of Hepatology, Numer 68/2, 2018, Strona(/y) 326-334, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2017.10.006

The bidirectional impacts of alcohol consumption and the metabolic syndrome: Cofactors for progressive fatty liver disease

Autorzy: Marie Boyle, Steven Masson, Quentin M. Anstee
Opublikowane w: Journal of Hepatology, Numer 68/2, 2018, Strona(/y) 251-267, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2017.11.006

Hypoxia-inducible factor 2α drives nonalcoholic fatty liver progression by triggering hepatocyte release of histidine-rich glycoprotein

Autorzy: Elisabetta Morello, Salvatore Sutti, Beatrice Foglia, Erica Novo, Stefania Cannito, Claudia Bocca, Martina Rajsky, Stefania Bruzzì, Maria Lorena Abate, Chiara Rosso, Cristina Bozzola, Ezio David, Elisabetta Bugianesi, Emanuele Albano, Maurizio Parola
Opublikowane w: Hepatology, Numer 67/6, 2018, Strona(/y) 2196-2214, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.29754

Determinants of fibrosis progression and regression in NASH

Autorzy: Detlef Schuppan, Rambabu Surabattula, Xiao Yu Wang
Opublikowane w: Journal of Hepatology, Numer 68/2, 2018, Strona(/y) 238-250, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2017.11.012

Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) – an 11-Year Prospective Study

Autorzy: Susanna Lallukka, Sanja Sädevirta, Markus T. Kallio, Panu K. Luukkonen, You Zhou, Antti Hakkarainen, Nina Lundbom, Marju Orho-Melander, Hannele Yki-Järvinen
Opublikowane w: Scientific Reports, Numer 7/1, 2017, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-017-14706-0

Fatty Acid and Glucose Sensors in Hepatic Lipid Metabolism: Implications in NAFLD

Autorzy: Michael Allison, Julian Griffin, Michele Vacca, Antonio Vidal-Puig
Opublikowane w: Seminars in Liver Disease, Numer 35/03, 2015, Strona(/y) 250-261, ISSN 0272-8087
Wydawca: Thieme Medical Publishers
DOI: 10.1055/s-0035-1562945

Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease

Autorzy: Quentin M. Anstee, Devanshi Seth, Christopher P. Day
Opublikowane w: Gastroenterology, Numer 150/8, 2016, Strona(/y) 1728-1744.e7, ISSN 0016-5085
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2016.01.037

Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease

Autorzy: Timothy Hardy, Mujdat Zeybel, Christopher P Day, Christian Dipper, Steven Masson, Stuart McPherson, Elsbeth Henderson, Dina Tiniakos, Steve White, Jeremy French, Derek A Mann, Quentin M Anstee, Jelena Mann
Opublikowane w: Gut, Numer 0, 1-8, 2016, Strona(/y) gutjnl-2016-311526, ISSN 0017-5749
Wydawca: BMJ Publishing Group
DOI: 10.1136/gutjnl-2016-311526

Review article: emerging anti-fibrotic therapies in the treatment of non-alcoholic steatohepatitis

Autorzy: M. Noureddin, Q. M. Anstee, R. Loomba
Opublikowane w: Alimentary Pharmacology & Therapeutics, Numer 43/11, 2016, Strona(/y) 1109-1123, ISSN 0269-2813
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/apt.13620

The Genetics of Nonalcoholic Fatty Liver Disease: Spotlight on PNPLA3 and TM6SF2

Autorzy: Christopher Day, Quentin Anstee
Opublikowane w: Seminars in Liver Disease, Numer 35/03, 2015, Strona(/y) 270-290, ISSN 0272-8087
Wydawca: Thieme Medical Publishers
DOI: 10.1055/s-0035-1562947

Serum endotrophin identifies optimal responders to PPARγ agonists in type 2 diabetes

Autorzy: Morten A. Karsdal, Kim Henriksen, Federica Genovese, Diana J. Leeming, Mette J. Nielsen, Bente J. Riis, Claus Christiansen, Inger Byrjalsen, Detlef Schuppan
Opublikowane w: Diabetologia, Numer 60/1, 2017, Strona(/y) 50-59, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-016-4094-1

Genetics of Alcoholic Liver Disease

Autorzy: Ann Daly, Christopher Day, Quentin Anstee
Opublikowane w: Seminars in Liver Disease, Numer 35/04, 2015, Strona(/y) 361-374, ISSN 0272-8087
Wydawca: Thieme Medical Publishers
DOI: 10.1055/s-0035-1567832

Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum

Autorzy: Timothy Hardy, Fiona Oakley, Quentin M. Anstee, Christopher P. Day
Opublikowane w: Annual Review of Pathology: Mechanisms of Disease, Numer 11/1, 2016, Strona(/y) 451-496, ISSN 1553-4006
Wydawca: Annual Reviews, Inc.
DOI: 10.1146/annurev-pathol-012615-044224

Peripheral insulin resistance predicts liver damage in nondiabetic subjects with nonalcoholic fatty liver disease

Autorzy: Chiara Rosso, Lavinia Mezzabotta, Melania Gaggini, Federico Salomone, Roberto Gambino, Andrea Marengo, Francesca Saba, Ester Vanni, Rami I.K. Jouness, Chiara Saponaro, Emma Buzzigoli, Gian Paolo Caviglia, Maria Lorena Abate, Antonina Smedile, Mario Rizzetto, Maurizio Cassader, Amalia Gastaldelli, Elisabetta Bugianesi
Opublikowane w: Hepatology, Numer 63/1, 2016, Strona(/y) 107-116, ISSN 0270-9139
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hep.28287

Systematic review of bariatric surgery liver biopsies clarifies the natural history of liver disease in patients with severe obesity

Autorzy: Pierre Bedossa, Joan Tordjman, Judith Aron-Wisnewsky, Christine Poitou, Jean-Michel Oppert, Adriana Torcivia, Jean-Luc Bouillot, Valerie Paradis, Vlad Ratziu, Karine Clément
Opublikowane w: Gut, Numer 66/9, 2017, Strona(/y) 1688-1696, ISSN 0017-5749
Wydawca: BMJ Publishing Group
DOI: 10.1136/gutjnl-2016-312238

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

Autorzy: Panu K. Luukkonen, Sanja Sädevirta, You Zhou, Brandon Kayser, Ashfaq Ali, Linda Ahonen, Susanna Lallukka, Véronique Pelloux, Melania Gaggini, Ching Jian, Antti Hakkarainen, Nina Lundbom, Helena Gylling, Anne Salonen, Matej Orešič, Tuulia Hyötyläinen, Marju Orho-Melander, Aila Rissanen, Amalia Gastaldelli, Karine Clément, Leanne Hodson, Hannele Yki-Järvinen
Opublikowane w: Diabetes Care, Numer 41/8, 2018, Strona(/y) 1732-1739, ISSN 0149-5992
Wydawca: American Diabetes Association
DOI: 10.2337/dc18-0071

Genetics of alcoholic liver disease and non-alcoholic steatohepatitis

Autorzy: Emma Scott, Quentin M Anstee
Opublikowane w: Clinical Medicine, Numer 18/Suppl 2, 2018, Strona(/y) s54-s59, ISSN 1470-2118
Wydawca: Royal College of Physicians
DOI: 10.7861/clinmedicine.18-2-s54

Liver fibrosis: Direct antifibrotic agents and targeted therapies

Autorzy: Detlef Schuppan, Muhammad Ashfaq-Khan, Ai Ting Yang, Yong Ook Kim
Opublikowane w: Matrix Biology, Numer 68-69, 2018, Strona(/y) 435-451, ISSN 0945-053X
Wydawca: Elsevier BV
DOI: 10.1016/j.matbio.2018.04.006

Fibrosis and alcohol-related liver disease

Autorzy: Carolin Lackner, Dina Tiniakos
Opublikowane w: Journal of Hepatology, Numer 70/2, 2019, Strona(/y) 294-304, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2018.12.003

A spotlight on pathogenesis, interactions and novel therapeutic options in NAFLD

Autorzy: Ramy Younes, Elisabetta Bugianesi
Opublikowane w: Nature Reviews Gastroenterology & Hepatology, Numer 16/2, 2019, Strona(/y) 80-82, ISSN 1759-5045
Wydawca: Nature Publishing Group
DOI: 10.1038/s41575-018-0094-6

P465L-PPARγ mutation confers partial resistance to the hypolipidaemic action of fibrates

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