GENEtic DiSsection of Innate Immune Sensing and Signalling

Publikacje

Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations

Autorzy: Sarah Kim-Hellmuth, Matthias Bechheim, Benno Pütz, Pejman Mohammadi, Yohann Nédélec, Nicholas Giangreco, Jessica Becker, Vera Kaiser, Nadine Fricker, Esther Beier, Peter Boor, Stephane E. Castel, Markus M. Nöthen, Luis B. Barreiro, Joseph K. Pickrell, Bertram Müller-Myhsok, Tuuli Lappalainen, Johannes Schumacher, Veit Hornung
Opublikowane w: Nature Communications, Numer 8/1, 2017, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-017-00366-1

Alternative inflammasome activation enables IL-1β release from living cells

Autorzy: Moritz M Gaidt, Veit Hornung
Opublikowane w: Current Opinion in Immunology, Numer 44, 2017, Strona(/y) 7-13, ISSN 0952-7915
Wydawca: Elsevier BV
DOI: 10.1016/j.coi.2016.10.007

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3

Autorzy: Moritz M. Gaidt, Thomas S. Ebert, Dhruv Chauhan, Katharina Ramshorn, Francesca Pinci, Sarah Zuber, Fionan O’Duill, Jonathan L. Schmid-Burgk, Florian Hoss, Raymund Buhmann, Georg Wittmann, Eicke Latz, Marion Subklewe, Veit Hornung
Opublikowane w: Cell, Numer 171/5, 2017, Strona(/y) 1110-1124.e18, ISSN 0092-8674
Wydawca: Cell Press
DOI: 10.1016/j.cell.2017.09.039

CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism

Autorzy: Jonathan L. Schmid-Burgk, Klara Höning, Thomas S. Ebert, Veit Hornung
Opublikowane w: Nature Communications, Numer 7, 2016, Strona(/y) 12338, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms12338

A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation

Autorzy: Jonathan L. Schmid-Burgk, Dhruv Chauhan, Tobias Schmidt, Thomas S. Ebert, Julia Reinhardt, Elmar Endl, Veit Hornung
Opublikowane w: Journal of Biological Chemistry, Numer 291/1, 2016, Strona(/y) 103-109, ISSN 0021-9258
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.C115.700492

DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer

Autorzy: Søren R. Paludan, Line S. Reinert, Veit Hornung
Opublikowane w: Nature Reviews Immunology, Numer 19/3, 2019, Strona(/y) 141-153, ISSN 1474-1733
Wydawca: Nature Publishing Group
DOI: 10.1038/s41577-018-0117-0

Molecular mechanisms and cellular functions of cGAS–STING signalling

Autorzy: Karl-Peter Hopfner, Veit Hornung
Opublikowane w: Nature Reviews Molecular Cell Biology, 2020, ISSN 1471-0072
Wydawca: Nature Publishing Group
DOI: 10.1038/s41580-020-0244-x

TLR8 Is a Sensor of RNase T2 Degradation Products

Autorzy: Wilhelm Greulich, Mirko Wagner, Moritz M. Gaidt, Che Stafford, Yiming Cheng, Andreas Linder, Thomas Carell, Veit Hornung
Opublikowane w: Cell, Numer 179/6, 2019, Strona(/y) 1264-1275.e13, ISSN 0092-8674
Wydawca: Cell Press
DOI: 10.1016/j.cell.2019.11.001

C-tag TNF: a reporter system to study TNF shedding

Autorzy: Francesca Pinci, Moritz M Gaidt, Christophe Jung, Gunnar Kuut, Margaret A Jackson, Stefan Bauernfried, Veit Hornung
Opublikowane w: Journal of Biological Chemistry, 2020, Strona(/y) jbc.RA120.015248, ISSN 0021-9258
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra120.015248

Human NLRP1 is a sensor for double-stranded RNA

Autorzy: Stefan Bauernfried, Matthias J. Scherr, Andreas Pichlmair, Karl E. Duderstadt, Veit Hornung
Opublikowane w: Science, 2020, Strona(/y) eabd0811, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.abd0811

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