New therapies for myeloproliferative diseases based on multi-stage and -system analyses of the haematopoietic stem-cell niche

Publikacje

Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis

Autorzy: Anke J Roelofs, Karolina Kania, Alexandra J Rafipay, Meike Sambale, Stephanie T Kuwahara, Fraser L Collins, Joanna Smeeton, Maxwell A Serowoky, Lynn Rowley, Hui Wang, René Gronewold, Chrysa Kapeni, Simón Méndez-Ferrer, Christopher B Little, John F Bateman, Thomas Pap, Francesca V Mariani, Joanna Sherwood, J Gage Crump, Cosimo De Bari
Opublikowane w: Annals of the Rheumatic Diseases, Numer 79/12, 2020, Strona(/y) 1625-1634, ISSN 0003-4967
Wydawca: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2020-218350

Human and mouse leukocytes: different clockwork

Autorzy: Simón Méndez-Ferrer
Opublikowane w: Blood, Numer 130/18, 2017, Strona(/y) 1960-1961, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2017-09-805374

Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia

Autorzy: Maurizio Mangolini, Frederik Götte, Andrew Moore, Tim Ammon, Madlen Oelsner, Gloria Lutzny-Geier, Ludger Klein-Hitpass, James C. Williamson, Paul J. Lehner, Jan Dürig, Michael Möllmann, Lívia Rásó-Barnett, Katherine Hughes, Antonella Santoro, Simón Méndez-Ferrer, Robert A. J. Oostendorp, Ursula Zimber-Strobl, Christian Peschel, Daniel J. Hodson, Marc Schmidt-Supprian, Ingo Ringshausen
Opublikowane w: Nature Communications, Numer 9/1, 2018, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-018-06069-5

Role of <i>VHL</i>, <i>HIF1A</i> and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate

Autorzy: Anna Merlo, Cristóbal Bernardo-Castiñeira, Inés Sáenz-de-Santa-María, Ana S Pitiot, Milagros Balbín, Aurora Astudillo, Nuria Valdés, Bartolomé Scola, Raquel Del Toro, Simón Méndez-Ferrer, José I Piruat, Carlos Suarez, María-Dolores Chiara
Opublikowane w: Oncotarget, Numer 8/4, 2017, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.14265

Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes

Autorzy: Andrés García-García, Claudia Korn, María García-Fernández, Olivia Domingues, Javier Villadiego, Daniel Martín-Pérez, Joan Isern, José A. Bejarano-García, Jacques Zimmer, José A. Pérez-Simón, Juan J. Toledo-Aral, Tatiana Michel, Matti S. Airaksinen, Simón Méndez-Ferrer
Opublikowane w: Blood, Numer 133/3, 2019, Strona(/y) 224-236, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2018-08-867648

T-ALL: several homes rather than homeless?

Autorzy: Justyna Rak, Simón Méndez-Ferrer
Opublikowane w: Immunology and Cell Biology, Numer 95/1, 2016, Strona(/y) 1-2, ISSN 0818-9641
Wydawca: Blackwell Publishing Inc.
DOI: 10.1038/icb.2016.103

Nestin+ cells direct inflammatory cell migration in atherosclerosis

Autorzy: Raquel del Toro, Raphael Chèvre, Cristina Rodríguez, Antonio Ordóñez, José Martínez-González, Vicente Andrés, Simón Méndez-Ferrer
Opublikowane w: Nature Communications, Numer 7, 2016, Strona(/y) 12706, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms12706

Under Pressure: When a Transformed Environment Pushes Cells to Malignancy

Autorzy: María García-Fernández, Simón Méndez-Ferrer
Opublikowane w: Cell Stem Cell, Numer 19/5, 2016, Strona(/y) 559-560, ISSN 1934-5909
Wydawca: Cell Press
DOI: 10.1016/j.stem.2016.10.012

The European Hematology Association Roadmap for European Hematology Research: a consensus document

Autorzy: A. Engert, C. Balduini, A. Brand, B. Coiffier, C. Cordonnier, H. Dohner, T. D. de Wit, S. Eichinger, W. Fibbe, T. Green, F. de Haas, A. Iolascon, T. Jaffredo, F. Rodeghiero, G. Salles, J. J. Schuringa, J. J. Schuringa, T. Jaffredo, B. Coiffier, G. Salles, H. Dohner, A. Iolascon, C. Balduini, S. Eichinger, A. Brand, C. Cordonnier, W. Fibbe
Opublikowane w: Haematologica, Numer 101/2, 2016, Strona(/y) 115-208, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2015.136739

Myeloid malignancies and the microenvironment

Autorzy: Claudia Korn, Simón Méndez-Ferrer
Opublikowane w: Blood, Numer 129/7, 2017, Strona(/y) 811-822, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2016-09-670224

The hematopoietic stem-cell niche in health and leukemia

Autorzy: Abel Sánchez-Aguilera, Simón Méndez-Ferrer
Opublikowane w: Cellular and Molecular Life Sciences, Numer 74/4, 2017, Strona(/y) 579-590, ISSN 1420-682X
Wydawca: Birkhauser Verlag
DOI: 10.1007/s00018-016-2306-y

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

Autorzy: Ya-Hsuan Ho, Raquel del Toro, José Rivera-Torres, Justyna Rak, Claudia Korn, Andrés García-García, David Macías, Cristina González-Gómez, Alberto del Monte, Monika Wittner, Amie K. Waller, Holly R. Foster, Carlos López-Otín, Randall S. Johnson, Claus Nerlov, Cedric Ghevaert, William Vainchenker, Fawzia Louache, Vicente Andrés, Simón Méndez-Ferrer
Opublikowane w: Cell Stem Cell, Numer 25/3, 2019, Strona(/y) 407-418.e6, ISSN 1934-5909
Wydawca: Cell Press
DOI: 10.1016/j.stem.2019.06.007

Haematopoietic stem cells in perisinusoidal niches are protected from ageing

Autorzy: Mehmet Saçma, Johannes Pospiech, Ruzhica Bogeska, Walter de Back, Jan-Philipp Mallm, Vadim Sakk, Karin Soller, Gina Marka, Angelika Vollmer, Rebekah Karns, Nina Cabezas-Wallscheid, Andreas Trumpp, Simón Méndez-Ferrer, Michael D. Milsom, Medhanie A. Mulaw, Hartmut Geiger, Maria Carolina Florian
Opublikowane w: Nature Cell Biology, Numer 21/11, 2019, Strona(/y) 1309-1320, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-019-0418-y

Updates on the hematologic tumor microenvironment and its therapeutic targeting

Autorzy: Dorian Forte, Daniela S. Krause, Michael Andreeff, Dominique Bonnet, Simón Méndez-Ferrer
Opublikowane w: Haematologica, Numer 104/10, 2019, Strona(/y) 1928-1934, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.195396

Molecular interactome between HSCs and their niches

Autorzy: Simón Méndez-Ferrer
Opublikowane w: Blood, Numer 134/15, 2019, Strona(/y) 1197-1198, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood.2019002615

Bone marrow niches in haematological malignancies

Autorzy: Simón Méndez-Ferrer, Dominique Bonnet, David P. Steensma, Robert P. Hasserjian, Irene M. Ghobrial, John G. Gribben, Michael Andreeff , Daniela S. Krause
Opublikowane w: Nature Reviews Cancer, 2020, ISSN 1474-175X
Wydawca: Nature Publishing Group
DOI: 10.1038/s41568-020-0245-2

Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance

Autorzy: Karin Golan, Anju Kumari, Orit Kollet, Eman Khatib-Massalha, Mohana Devi Subramaniam, Zulma S. Ferreira, Francesca Avemaria, Sylwia Rzeszotek, Andrés García-García, Stephanie Xie, Eugenia Flores-Figueroa, Shiri Gur-Cohen, Tomer Itkin, Aya Ludin-Tal, Hassan Massalha, Biana Bernshtein, Andrzej K. Ciechanowicz, Alexander Brandis, Tevie Mehlman, Suditi Bhattacharya, Mayla Bertagna, Hui Cheng, Ekate
Opublikowane w: Cell Stem Cell, Numer 23/4, 2018, Strona(/y) 572-585.e7, ISSN 1934-5909
Wydawca: Cell Press
DOI: 10.1016/j.stem.2018.08.002

The sympathomimetic agonist mirabegron did not lower JAK2 -V617F allele burden, but restored nestin-positive cells and reduced reticulin fibrosis in patients with myeloproliferative neoplasms: results of phase II study SAKK 33/14

Autorzy: Beatrice Drexler, Jakob R. Passweg, Alexandar Tzankov, Martin Bigler, Alexandre PA Theocharides, Nathan Cantoni, Peter Keller, Georg Stussi, Axel Ruefer, Rudolf Benz, Geneviève Favre, Pontus Lundberg, Ronny Nienhold, Andrea Fuhrer, Christine Biaggi, Markus G. Manz, Mario Bargetzi, Simon Mendez-Ferrer, Radek C. Skoda
Opublikowane w: Haematologica, Numer 104/4, 2019, Strona(/y) 710-716, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.200014

Vascular Interstitial Cells in Retinal Arteriolar Annuli Are Altered During Hypertension

Autorzy: David Ramos, Joana Catita, Mariana López-Luppo, Andreia Valença, Aina Bonet, Ana Carretero, Marc Navarro, Victor Nacher, Simon Mendez-Ferrer, Anna Meseguer, Alba Casellas, Luísa Mendes-Jorge, Jesús Ruberte
Opublikowane w: Investigative Opthalmology & Visual Science, Numer 60/2, 2019, Strona(/y) 473, ISSN 1552-5783
Wydawca: Association for Research in Vision and Ophthalmology
DOI: 10.1167/iovs.18-25000

Microenvironmental contributions to hematopoietic stem cell aging

Autorzy: Ya-Hsuan Ho, Simón Méndez-Ferrer
Opublikowane w: Haematologica, Numer 105/1, 2020, Strona(/y) 38-46, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2018.211334

Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy

Autorzy: Dorian Forte, María García-Fernández, Abel Sánchez-Aguilera, Vaia Stavropoulou, Claire Fielding, Daniel Martín-Pérez, Juan Antonio López, Ana S.H. Costa, Laura Tronci, Efterpi Nikitopoulou, Michael Barber, Paolo Gallipoli, Ludovica Marando, Carlos López Fernández de Castillejo, Alexandar Tzankov, Sabine Dietmann, Michele Cavo, Lucia Catani, Antonio Curti, Jesús Vázquez, Christian Frezza
Opublikowane w: Cell Metabolism, Numer 32/5, 2020, Strona(/y) 829-843.e9, ISSN 1550-4131
Wydawca: Cell Press
DOI: 10.1016/j.cmet.2020.09.001

Neuronal regulation of bone marrow stem cell niches

Autorzy: Claire Fielding, Simón Méndez-Ferrer
Opublikowane w: F1000Research, Numer 9, 2020, Strona(/y) 614, ISSN 2046-1402
Wydawca: F1000 Research Ltd.
DOI: 10.12688/f1000research.22554.1

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