Structure of paramagnetic integral membrane metalloproteins by MAS-NMR

Informacje na temat projektu

P-MEM-NMR

Identyfikator umowy o grant: 648974

DOI

10.3030/648974

Projekt został zamknięty

Data podpisania przez KE 6 Lipca 2015

Data rozpoczęcia 1 Września 2015

Data zakończenia 31 Sierpnia 2021

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 2 499 375,00

Wkład UE

€ 2 499 375,00

Koordynowany przez

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (30)

Probing Membrane Protein Insertion into Lipid Bilayers by Solid‐State NMR

Autorzy: Eszter E. Najbauer, Kumar Tekwani Movellan, Tobias Schubeis, Tom Schwarzer, Kathrin Castiglione, Karin Giller, Guido Pintacuda, Stefan Becker, Loren B. Andreas
Opublikowane w: ChemPhysChem, 2018, ISSN 1439-4235
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cphc.201800793

Multimodal Response to Copper Binding in Superoxide Dismutase Dynamics

Autorzy: Marta Bonaccorsi, Michael J. Knight, Tanguy Le Marchand, Hugh R. W. Dannatt, Tobias Schubeis, Loïc Salmon, Isabella C. Felli, Lyndon Emsley, Roberta Pierattelli, Guido Pintacuda
Opublikowane w: Journal of the American Chemical Society, Numer 142/46, 2020, Strona(/y) 19660-19667, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.0c09242

Backbone assignment of crystalline E. coli maltose binding protein

Autorzy: Tobias Schubeis, Jan Stanek, Guido Pintacuda
Opublikowane w: Biomolecular NMR Assignments, Numer 15/2, 2021, Strona(/y) 317-322, ISSN 1874-2718
Wydawca: Springer Verlag
DOI: 10.1007/s12104-021-10023-w

Structural and molecular basis of cross-seeding barriers in amyloids

Autorzy: Asen Daskalov, Denis Martinez, Virginie Coustou, Nadia El Mammeri, Mélanie Berbon, Loren B. Andreas, Benjamin Bardiaux, Jan Stanek, Abdelmajid Noubhani, Brice Kauffmann, Joseph S. Wall, Guido Pintacuda, Sven J. Saupe, Birgit Habenstein, Antoine Loquet
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 118/1, 2020, Strona(/y) e2014085118, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2014085118

A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL

Autorzy: Tobias Schubeis, Tanguy Le Marchand, Csaba Daday, Wojciech Kopec, Kumar Tekwani Movellan, Jan Stanek, Tom S. Schwarzer, Kathrin Castiglione, Bert L. de Groot, Guido Pintacuda, Loren B. Andreas
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 117/35, 2020, Strona(/y) 21014-21021, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2002598117

Paramagnetic NMR in solution and the solid state

Autorzy: Andrew J. Pell, Guido Pintacuda, Clare P. Grey
Opublikowane w: Progress in Nuclear Magnetic Resonance Spectroscopy, Numer 111, 2019, Strona(/y) 1-271, ISSN 0079-6565
Wydawca: Elsevier BV
DOI: 10.1016/j.pnmrs.2018.05.001

Picometer Resolution Structure of the Coordination Sphere in the Metal-Binding Site in a Metalloprotein by NMR

Autorzy: Andrea Bertarello, Ladislav Benda, Kevin J. Sanders, Andrew J. Pell, Michael J. Knight, Vladimir Pelmenschikov, Leonardo Gonnelli, Isabella C. Felli, Martin Kaupp, Lyndon Emsley, Roberta Pierattelli, Guido Pintacuda
Opublikowane w: Journal of the American Chemical Society, Numer 142/39, 2020, Strona(/y) 16757-16765, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.0c07339

Resonance assignment of the outer membrane protein AlkL in lipid bilayers by proton-detected solid-state NMR

Autorzy: Tobias Schubeis, Tom S. Schwarzer, Tanguy Le Marchand, Jan Stanek, Kumar Tekwani Movellan, Kathrin Castiglione, Guido Pintacuda, Loren B. Andreas
Opublikowane w: Biomolecular NMR Assignments, Numer 14/2, 2020, Strona(/y) 295-300, ISSN 1874-2718
Wydawca: Springer Verlag
DOI: 10.1007/s12104-020-09964-5

Proton-detected fast-magic-angle spinning NMR of paramagnetic inorganic solids

Autorzy: Jan Blahut, Ladislav Benda, Arthur L. Lejeune, Kevin J. Sanders, Benjamin Burcher, Erwann Jeanneau, David Proriol, Leonor Catita, Pierre-Alain R. Breuil, Anne-Agathe Quoineaud, Andrew J. Pell, Guido Pintacuda
Opublikowane w: RSC Advances, Numer 11/47, 2021, Strona(/y) 29870-29876, ISSN 2046-2069
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1ra04110j

Protein structural dynamics by Magic-Angle Spinning NMR

Autorzy: Marta Bonaccorsi, Tanguy Le Marchand, Guido Pintacuda
Opublikowane w: Current Opinion in Structural Biology, Numer 70, 2021, Strona(/y) 34-43, ISSN 0959-440X
Wydawca: Elsevier BV
DOI: 10.1016/j.sbi.2021.02.008

Monitoring Dynamics, Structure, and Magnetism of Switchable Metal–Organic Frameworks via 1 H‐Detected MAS NMR

Autorzy: Jan Blahut, Arthur L. Lejeune, Sebastian Ehrling, Irena Senkovska, Stefan Kaskel, Florian M. Wisser, Guido Pintacuda
Opublikowane w: Angewandte Chemie International Edition, Numer 60/40, 2021, Strona(/y) 21778-21783, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202107032

Structural Analysis of an Antigen Chemically Coupled on Virus‐Like Particles in Vaccine Formulation

Autorzy: Kristaps Jaudzems, Anna Kirsteina, Tobias Schubeis, Gilles Casano, Olivier Ouari, Janis Bogans, Andris Kazaks, Kaspars Tars, Anne Lesage, Guido Pintacuda
Opublikowane w: Angewandte Chemie International Edition, Numer 60/23, 2021, Strona(/y) 12847-12851, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202013189

Protein NMR Resonance Assignment without Spectral Analysis: 5D SOlid‐State Automated Projection SpectroscopY (SO‐APSY)

Autorzy: Henry W. Orton, Jan Stanek, Tobias Schubeis, Dylan Foucaudeau, Claire Ollier, Adrian W. Draney, Tanguy Le Marchand, Diane Cala‐De Paepe, Isabella C. Felli, Roberta Pierattelli, Sebastian Hiller, Wolfgang Bermel, Guido Pintacuda
Opublikowane w: Angewandte Chemie International Edition, Numer 59/6, 2020, Strona(/y) 2380-2384, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201912211

Impact of Magnetic Field Strength on Resolution and Sensitivity of Proton Resonances in Biological Solids

Autorzy: Kai Xue, Riddhiman Sarkar, Daniela Lalli, Benita Koch, Guido Pintacuda, Zdenek Tosner, Bernd Reif
Opublikowane w: The Journal of Physical Chemistry C, Numer 124/41, 2020, Strona(/y) 22631-22637, ISSN 1932-7447
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpcc.0c05407

Proton-Based Structural Analysis of a Heptahelical Transmembrane Protein in Lipid Bilayers

Autorzy: Daniela Lalli, Matthew N. Idso, Loren B. Andreas, Sunyia Hussain, Naomi Baxter, Songi Han, Bradley F. Chmelka, Guido Pintacuda
Opublikowane w: Journal of the American Chemical Society, Numer 139/37, 2017, Strona(/y) 13006-13012, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.7b05269

Selective 1 H– 1 H Distance Restraints in Fully Protonated Proteins by Very Fast Magic-Angle Spinning Solid-State NMR

Autorzy: Mukul G. Jain, Daniela Lalli, Jan Stanek, Chandrakala Gowda, Satya Prakash, Tom S. Schwarzer, Tobias Schubeis, Kathrin Castiglione, Loren B. Andreas, P. K. Madhu, Guido Pintacuda, Vipin Agarwal
Opublikowane w: The Journal of Physical Chemistry Letters, Numer 8/11, 2017, Strona(/y) 2399-2405, ISSN 1948-7185
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpclett.7b00983

Paramagnetic Properties of a Crystalline Iron–Sulfur Protein by Magic-Angle Spinning NMR Spectroscopy

Autorzy: Andrea Bertarello, Tobias Schubeis, Carmelo Fuccio, Enrico Ravera, Marco Fragai, Giacomo Parigi, Lyndon Emsley, Guido Pintacuda, Claudio Luchinat
Opublikowane w: Inorganic Chemistry, Numer 56/11, 2017, Strona(/y) 6624-6629, ISSN 0020-1669
Wydawca: American Chemical Society
DOI: 10.1021/acs.inorgchem.7b00674

NMR Spectroscopic Assignment of Backbone and Side-Chain Protons in Fully Protonated Proteins: Microcrystals, Sedimented Assemblies, and Amyloid Fibrils

Autorzy: Jan Stanek, Loren B. Andreas, Kristaps Jaudzems, Diane Cala, Daniela Lalli, Andrea Bertarello, Tobias Schubeis, Inara Akopjana, Svetlana Kotelovica, Kaspars Tars, Andrea Pica, Serena Leone, Delia Picone, Zhi-Qiang Xu, Nicholas E. Dixon, Denis Martinez, Mélanie Berbon, Nadia El Mammeri, Abdelmajid Noubhani, Sven Saupe, Birgit Habenstein, Antoine Loquet, Guido Pintacuda
Opublikowane w: Angewandte Chemie International Edition, Numer 55/50, 2016, Strona(/y) 15504-15509, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201607084

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

Autorzy: Loren B. Andreas, Kristaps Jaudzems, Jan Stanek, Daniela Lalli, Andrea Bertarello, Tanguy Le Marchand, Diane Cala-De Paepe, Svetlana Kotelovica, Inara Akopjana, Benno Knott, Sebastian Wegner, Frank Engelke, Anne Lesage, Lyndon Emsley, Kaspars Tars, Torsten Herrmann, Guido Pintacuda
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 113/33, 2016, Strona(/y) 9187-9192, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1602248113

1 H magic-angle spinning NMR evolves as a powerful new tool for membrane proteins

Autorzy: Tobias Schubeis, Tanguy Le Marchand, Loren B. Andreas, Guido Pintacuda
Opublikowane w: Journal of Magnetic Resonance, Numer 287, 2018, Strona(/y) 140-152, ISSN 1090-7807
Wydawca: Academic Press
DOI: 10.1016/j.jmr.2017.11.014

Low-power broadband solid-state MAS NMR of 14 N

Autorzy: Andrew J. Pell, Kevin J. Sanders, Sebastian Wegner, Guido Pintacuda, Clare P. Grey
Opublikowane w: The Journal of Chemical Physics, Numer 146/19, 2017, Strona(/y) 194202, ISSN 0021-9606
Wydawca: American Institute of Physics
DOI: 10.1063/1.4983220

Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity

Autorzy: Tanguy Le Marchand, Matteo de Rosa, Nicola Salvi, Benedetta Maria Sala, Loren B. Andreas, Emeline Barbet-Massin, Pietro Sormanni, Alberto Barbiroli, Riccardo Porcari, Cristiano Sousa Mota, Daniele de Sanctis, Martino Bolognesi, Lyndon Emsley, Vittorio Bellotti, Martin Blackledge, Carlo Camilloni, Guido Pintacuda, Stefano Ricagno
Opublikowane w: Nature Communications, Numer 9/1, 2018, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-018-04078-y

Is protein deuteration beneficial for proton detected solid-state NMR at and above 100 kHz magic-angle spinning?

Autorzy: Diane Cala-De Paepe, Jan Stanek, Kristaps Jaudzems, Kaspars Tars, Loren B. Andreas, Guido Pintacuda
Opublikowane w: Solid State Nuclear Magnetic Resonance, Numer 87, 2017, Strona(/y) 126-136, ISSN 0926-2040
Wydawca: Academic Press
DOI: 10.1016/j.ssnmr.2017.07.004

Straightforward Access to Stable, 16-Valence-Electron Phosphine-Stabilized Fe 0 Olefin Complexes and Their Reactivity

Autorzy: Benjamin Burcher, Kevin J. Sanders, Ladislav Benda, Guido Pintacuda, Erwann Jeanneau, Andreas A. Danopoulos, Pierre Braunstein, Hélène Olivier-Bourbigou, Pierre-Alain R. Breuil
Opublikowane w: Organometallics, Numer 36/3, 2017, Strona(/y) 605-613, ISSN 0276-7333
Wydawca: American Chemical Society
DOI: 10.1021/acs.organomet.6b00803

Local and Global Dynamics in Klebsiella pneumoniae Outer Membrane Protein a in Lipid Bilayers Probed at Atomic Resolution

Autorzy: Olivier Saurel, Iordan Iordanov, Guillaume Nars, Pascal Demange, Tanguy Le Marchand, Loren B. Andreas, Guido Pintacuda, Alain Milon
Opublikowane w: Journal of the American Chemical Society, Numer 139/4, 2017, Strona(/y) 1590-1597, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.6b11565

Broadband MAS NMR spectroscopy in the low-power limit

Autorzy: Kevin J. Sanders, Andrew J. Pell, Sebastian Wegner, Clare P. Grey, Guido Pintacuda
Opublikowane w: Chemical Physics Letters, Numer 697, 2018, Strona(/y) 29-37, ISSN 0009-2614
Wydawca: Elsevier BV
DOI: 10.1016/j.cplett.2018.01.028

3D structure determination of amyloid fibrils using solid-state NMR spectroscopy

Autorzy: Antoine Loquet, Nadia El Mammeri, Jan Stanek, Mélanie Berbon, Benjamin Bardiaux, Guido Pintacuda, Birgit Habenstein
Opublikowane w: Methods, 2018, ISSN 1046-2023
Wydawca: Academic Press
DOI: 10.1016/j.ymeth.2018.03.014

Rapid access to RNA resonances by proton-detected solid-state NMR at >100 kHz MAS

Autorzy: Alexander Marchanka, Jan Stanek, Guido Pintacuda, Teresa Carlomagno
Opublikowane w: Chemical Communications, Numer 54/65, 2018, Strona(/y) 8972-8975, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c8cc04437f

MAS dependent sensitivity of different isotopomers in selectively methyl protonated protein samples in solid state NMR

Autorzy: Kai Xue, Riddhiman Sarkar, Zdenek Tosner, Daniela Lalli, Carina Motz, Benita Koch, Guido Pintacuda, Bernd Reif
Opublikowane w: Journal of Biomolecular NMR, Numer 73/10-11, 2019, Strona(/y) 625-631, ISSN 0925-2738
Wydawca: Kluwer Academic Publishers
DOI: 10.1007/s10858-019-00274-0

Automated Backbone NMR Resonance Assignment of Large Proteins Using Redundant Linking from a Single Simultaneous Acquisition

Autorzy: Jan Stanek, Tobias Schubeis, Piotr Paluch, Peter Güntert, Loren B. Andreas, Guido Pintacuda
Opublikowane w: Journal of the American Chemical Society, Numer 142/12, 2020, Strona(/y) 5793-5799, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.0c00251

Non-peer reviewed articles (1)

Mg2+-dependent conformational equilibria in CorA: an integrated view on transport regulation

Autorzy: Nicolai Tidemand Johansen, Marta Bonaccorsi, Tone Bengtsen, Andreas Haahr Larsen, Frederik Grønbæk Tidemand, Martin Cramer Pedersen, Pie Huda, Jens Berndtsson, Tamim Darwish, Nageshwar Rao Yepuri, Anne Martel, Thomas Günther Pomorski, Andrea Bertarello, Mark Sansom, Mikaela Rapp, Ramon Crehuet, Tobias Schubeis, Kresten Lindorff-Larsen, Guido Pintacuda, Lise Arleth
Opublikowane w: bioRxiv, 2021, ISSN 2692-8205
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.08.20.457080