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Small vessel diseases in a mechanistic perspective: Targets for Intervention Affected pathways and mechanistic exploitation for prevention of stroke and dementia

Rezultaty

Publikacje

Relationship Between Blood Pressure and Incident Cardiovascular Disease

Autorzy: Malik et.al.
Opublikowane w: Hypertension, 2021, ISSN 0194-911X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.120.16534

Effect sizes of BOLD CVR, resting-state signal fluctuations and time delay measures for the assessment of hemodynamic impairment in carotid occlusion patients

Autorzy: Jill B. De Vis, Alex A. Bhogal, Jeroen Hendrikse, Esben T. Petersen, Jeroen C.W. Siero
Opublikowane w: NeuroImage, Numer 179, 2018, Strona(/y) 530-539, ISSN 1053-8119
Wydawca: Academic Press
DOI: 10.1016/j.neuroimage.2018.06.017

A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease.

Autorzy: Stringer MS, Lee H, Huuskonen MT, MacIntosh BJ, Brown R, Montagne A, Atwi S, Ramirez J, Jansen MA, Marshall I, Black SE, Zlokovic BV, Benveniste H, Wardlaw JM
Opublikowane w: Translational Stroke Research, 2020, ISSN 1868-4483
Wydawca: Springer Pub. Co.,
DOI: 10.1007/s12975-020-00843-8

Clinical management of cerebral small vessel disease: a call for a holistic approach.

Autorzy: Clancy U, Appleton JP, Arteaga C, Doubal FN, Bath PM, Wardlaw JM
Opublikowane w: Chinese medical journal, 2020, ISSN 0366-6999
Wydawca: Zhonghua Yixeuehui Zazhishe/Chinese Medical Association Publishing House
DOI: 10.1097/cm9.0000000000001177

Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis

Autorzy: Gill D, Georgakis MK, Zuber V, Karhunen V, Burgess S, Malik R, Dichgans M
Opublikowane w: Journal of the American Heart Association, Numer 9(14), 2020, Strona(/y) e016773, ISSN 2047-9980
Wydawca: Wiley-Blackwell
DOI: 10.1161/jaha.120.016773

Effects of cilostazol and isosorbide mononitrate on cerebral haemodynamics in the LACI-1 randomised controlled trial

Autorzy: Blair GW, Janssen E, Stringer MS, Thrippleton MJ, Chappell F, Shi Y, Hamilton I, Flathery K, Appleton JP, Doubal FN, Bath PM, Wardlaw JM
Opublikowane w: Stroke, 2021, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.121.034866

Impaired Cerebral Autoregulation After Subarachnoid Hemorrhage: A Quantitative Assessment Using a Mouse Model.

Autorzy: Koide M, Ferris HR, Nelson MT, Wellman GC.
Opublikowane w: Front Physiol, 2021, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.688468

Post-stroke Cognition at 1 and 3 Years Is Influenced by the Location of White Matter Hyperintensities in Patients With Lacunar Stroke

Autorzy: Maria del C. Valdés Hernández,1,* Tara Grimsley-Moore,2 Francesca M. Chappell,1 Michael J. Thrippleton,1 Paul A. Armitage,3 Eleni Sakka,1 Stephen Makin,4 and Joanna M. Wardlaw1
Opublikowane w: Front Neurol., 2021, ISSN 1662-453X
Wydawca: Frontiers
DOI: 10.3389/fneur.2021.634460

Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics

Autorzy: Tiedt S, Brandmaier S, Kollmeier H, Duering M, Artati A, Adamski J, Klein M, Liebig T, Holdt LM, Teupser D, Wang-Sattler R, Schwedhelm E, Gieger C, Dichgans M
Opublikowane w: Annals of Neurology, Numer 88(4), 2020, Strona(/y) 736-746, ISSN 1531-8249
Wydawca: Wiley
DOI: 10.1002/ana.25859

Dose-response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus

Autorzy: Burgess S, Malik R, Liu B, Mason AM, Georgakis MK, Dichgans M, Gill D
Opublikowane w: Diabetologia, Numer 64(4), 2021, Strona(/y) 845-849, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-020-05377-0

Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.

Autorzy: Kerkhofs D, van Hagen BT, Milanova IV, Schell KJ, van Essen H, Wijnands E, Goossens P, Blankesteijn WM, Unger T, Prickaerts J, Biessen EA, van Oostenbrugge RJ, Foulquier S
Opublikowane w: Theranostics, 2020, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000011783

Correlations in post-mortem imaging-histopathology studies of sporadic human cerebral small vessel disease: a systematic review

Autorzy: Catherine A Humphreys , Colin Smith , Joanna M Wardlaw
Opublikowane w: Neuropathol Appl Neurobiol, 2021, ISSN 1365-2990
Wydawca: John Wiley & Sons, Inc.
DOI: 10.1111/nan.12737

Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts

Autorzy: Nick A Weaver, Hugo J Kuijf, Hugo P Aben, Jill Abrigo, Hee-Joon Bae, Mélanie Barbay, Jonathan G Best, Régis Bordet, Francesca M Chappell, J Matthijs Biesbroek, Geert Jan Biessels
Opublikowane w: Lancet Neurol, 2021, ISSN 1474-4422
Wydawca: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(21)00060-0

Non-Invasive Assessment of Damping of Blood Flow Velocity Pulsatility in Cerebral Arteries With MRI

Autorzy: Tine Arts, MS,1 Laurien P. Onkenhout, MS,1 Raquel P. Amier, MS,3 Rob van der Geest, PhD,4 Thijs van Harten, MS,4 Jaap Kappelle, MD,2 Sanne Kuipers, MS,2 Matthijs J.P. van Osch, PhD,4 Ed T. van Bavel, PhD,5 Geert Jan Biessels, MD,2 and Jaco J.M. Zwanenburg
Opublikowane w: Journal of Magnetic Resonance Imaging, 2021, ISSN 1090-7807
Wydawca: Academic Press
DOI: 10.1002/jmri.27989

Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort

Autorzy: Okl Hamilton , S R Cox , L Ballerini , M E Bastin , J Corley , A J Gow , S Muñoz Maniega , P Redmond , M Del C Valdés Hernández , J M Wardlaw , I J Deary
Opublikowane w: Neurobiol Aging, 2021, ISSN 0197-4580
Wydawca: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2021.04.007

Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2×2 Factorial Mendelian Randomization Analysis.

Autorzy: Georgakis MK, Malik R, Burgess S, Dichgans M.
Opublikowane w: J Am Heart Assoc, Numer 2022 Jan 4, 2022, Strona(/y) 11(1):e023277, ISSN 2047-9980
Wydawca: Wiley-Blackwell
DOI: 10.1161/jaha.121.023277

Associations Between White Matter Hyperintensity Burden, Cerebral Blood Flow and Transit Time in Small Vessel Disease: An Updated Meta-Analysis

Autorzy: Catriona R Stewart , Michael S Stringer, Yulu Shi , Michael J Thrippleton, Joanna M Wardlaw
Opublikowane w: Front Neurol, 2021, ISSN 1662-453X
Wydawca: Frontiers
DOI: 10.3389/fneur.2021.647848

Circadian control of brain glymphatic and lymphatic fluid flow.

Autorzy: Hablitz LM, Plá V, Giannetto M, Vinitsky HS, Stæger FF, Metcalfe T, Nguyen R, Benrais A, Nedergaard M
Opublikowane w: Nature communications, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-020-18115-2

Genetically Predicted Blood Pressure Across the Lifespan: Differential Effects of Mean and Pulse Pressure on Stroke Risk

Autorzy: Georgakis MK, Gill D, Malik R, Protogerou AD, Webb AJS, Dichgans M
Opublikowane w: Hypertension, Numer 76(3), 2020, Strona(/y) 953-961, ISSN 1524-4563
Wydawca: American Heart Association
DOI: 10.1161/hypertensionaha.120.15136

Sources of systematic error in DCE-MRI estimation of low-level blood-brain barrier leakage

Autorzy: Cameron Manning,Michael Stringer,Ben Dickie,Una Clancy,Maria C. Valdés Hernandez,Stewart J. Wiseman,Daniela Jaime Garcia,Eleni Sakka,Walter H. Backes,Michael Ingrisch,Francesca Chappell,Fergus Doubal,Craig Buckley,Laura M. Parkes,Geoff J. M. Parker,Ian Marshall,Joanna M. Wardlaw,Michael J. Thrippleton
Opublikowane w: Magnetic Resonance in Medicine, 2021, ISSN 1522-2594
Wydawca: Wiley
DOI: 10.1002/mrm.28833

ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart

Autorzy: Guiling Zhao, Humberto C. Joca, Mark T. Nelson, W. Jonathan Lederer
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 117/13, 2020, Strona(/y) 7461-7470, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1922095117

Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the “ZOOM@SVDs ”study

Autorzy: Hilde van den Brink a , Anna Kopczak b , Tine Arts c , Laurien Onkenhout a , Jeroen C.W. Siero c , d , Jaco J.M. Zwanenburg c , Marco Duering b , e , f , Gordon W. Blair g , Fergus N.Doubal g , Michael S. Stringer g , Michael J. Thrippleton g , Hugo J. Kuijf h , Alberto de Luca a , g , Jeroen Hendrikse c , Joanna M. Wardlaw g , Martin Dichgans b , e , f , Geert Jan Biessels a , ∗ , on behalf of
Opublikowane w: Cerebral Circulation - Cognition and Behavior, 2021, ISSN 2666-2450
Wydawca: Elseveir
DOI: 10.1016/j.cccb.2021.100013

Cardiac Risk Factors for Stroke: A Comprehensive Mendelian Randomization Study

Autorzy: Frerich S, Malik R, Georgakis MK, Sinner MF, Kittner SJ, Mitchell BD, Dichgans M.
Opublikowane w: Stroke, 2021, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.121.036306

Zinc drives vasorelaxation by acting on sensory nerves, endothelium and smooth muscle

Autorzy: Betrie AH, Brock JA, Harraz OF, Bush AI, He G-W, Nelson MT, Angus JA, Wright CE, Ayton S
Opublikowane w: Nat Commun, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-23198-6

Early life predictors of late life cerebral small vessel disease in four prospective cohort studies.

Autorzy: Backhouse EV, Shenkin SD, McIntosh AM, Bastin ME, Whalley HC, Valdez Hernandez M, Muñoz Maniega S, Harris MA, Stolicyn A, Campbell A, Steele D, Waiter GD, Sandu AL, Waymont JMJ, Murray AD, Cox SR, de Rooij SR, Roseboom TJ, Wardlaw JM.
Opublikowane w: Brain, Numer 2021 Sep 28:awab331, 2021, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awab331

Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta-analysis.

Autorzy: Hamilton OKL, Backhouse EV, Janssen E, Jochems ACC, Maher C, Ritakari TE, Stevenson AJ, Xia L, Deary IJ, Wardlaw JM
Opublikowane w: Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020, ISSN 1552-5279
Wydawca: Alzheimer’s Association
DOI: 10.1002/alz.12221

Blood-brain barrier leakage at baseline and cognitive decline in cerebral small vessel disease: a 2-year follow-up study.

Autorzy: Kerkhofs D, Wong SM, Zhang E, Uiterwijk R, Hoff EI, Jansen JFA, Staals J, Backes WH, van Oostenbrugge RJ
Opublikowane w: Geroscience, 2021, ISSN 2509-2715
Wydawca: Springer
DOI: 10.1007/s11357-021-00399-x

Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936.

Autorzy: Hamilton OKL, Cox SR, Okely JA, Conte F, Ballerini L, Bastin ME, Corley J, Taylor AM, Page D, Gow AJ, Muñoz Maniega S, Redmond P, Valdés-Hernández MDC, Wardlaw JM, Deary IJ.
Opublikowane w: Transl Psychiatry., 2021, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.1038/s41398-021-01495-4

Sex differences in cerebral small vessel disease: a systematic review and meta-analysis.

Autorzy: Jiménez-Sánchez L, Hamilton OJ, Clancy U, Backhouse E, Stewart CR, Stringer MS, Doubal FN, Wardlaw JM
Opublikowane w: Front Neurol, 2021, ISSN 1662-453X
Wydawca: Frontiers
DOI: 10.3389/fneur.2021.756887

PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity

Autorzy: Dabertrand F, Harraz OF, Koide M, Longden TA, Rosehart AC, Hill-Eubanks DC, Joutel A, Nelson MT
Opublikowane w: PNAS, 2021, ISSN 1091-6490
Wydawca: PNAS
DOI: 10.1073/pnas.2025998118

Improving Clinical Detection of Acute Lacunar Stroke

Autorzy: Arba F, Mair G, Phillips S, Sandercock P, Wardlaw JM
Opublikowane w: Stroke, 2021, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.119.028402

Imaging NeuroVascular, Endothelial and STructural Integrity in prepAration to TrEat Small Vessel Diseases. The INVESTIGATE-SVDs study Protocol. Part of the SVDs@Target Project

Autorzy: Blair GW, Stringer MS, Thrippleton MJ, Chappell FM, Shuler K, Hamilton I, Garcia DJ, Doubal FN, Kopczak A, Duering M, Ingrisch M, Kerkhofs D, Staals J, van den Brink H, Arts T, Backes W,.
Opublikowane w: Cereb Circ Cogn Behav, 2021, ISSN 2666-2450
Wydawca: Elsevier
DOI: 10.1016/j.cccb.2021.100020

The striatum, the hippocampus, and short-term memory binding: Volumetric analysis of the subcortical grey matter's role in mild cognitive impairment

Autorzy: Maria C. Valdés Hernández, Rupert Clark, Szu-Han Wang, Federica Guazzo, Clara Calia, Vivek Pattan, John Starr, Sergio Della Sala, Mario Alfredo Parra
Opublikowane w: NeuroImage: Clinical, Numer 25, 2020, Strona(/y) 102158, ISSN 2213-1582
Wydawca: Elsevier BV
DOI: 10.1016/j.nicl.2019.102158

Mendelian randomization for studying the effects of perturbing drug targets

Autorzy: Gill. D. et. al
Opublikowane w: Wellcome Open Research, Numer 10;6:16, 2021, Strona(/y) 10;6:16, ISSN 2398-502X
Wydawca: F1000Research
DOI: 10.12688/wellcomeopenres.16544.2

Identification of plasma proteins relating to brain neurodegeneration and vascular pathology in cognitively normal individuals.

Autorzy: Shi L, Buchanan CR, Cox SR, Hillary RF, Marioni RE, Campbell A, Hayward C, Stolicyn A, Whalley HC, Harris MA, Waymont J, Waiter G, Backhouse E, Wardlaw JM, Steele D, Mcintosh A, Lovestone S, Buckley NJ, Nevado-Holgado AJ.
Opublikowane w: Alzheimers Dement, 2021, ISSN 1552-5279
Wydawca: Alzheimer’s Association
DOI: 10.1002/dad2.12240

Cerebral Vascular Dysfunctions Detected in Human Small Vessel Disease and Implications for Preclinical Studies.

Autorzy: Wardlaw JM, Benveniste H, Williams A.
Opublikowane w: Annu Rev Physiol, 2021, ISSN 1545-1585
Wydawca: Annual Reviews
DOI: 10.1146/annurev-physiol-060821-014521

Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice.

Autorzy: Giannetto M, Xia M, Stæger FF, Metcalfe T, Vinitsky HS, Dang JAML, Xavier ALR, Kress BT, Nedergaard M, Hablitz LM
Opublikowane w: Nature, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-72621-3

A Comparison of CVR Magnitude and Delay Assessed at 1.5 and 3T in Patients With Cerebral Small Vessel Disease.

Autorzy: Stringer MS, Blair GW, Shi Y, Hamilton I, Dickie DA, Doubal FN, Marshall IM, Thrippleton MJ, Wardlaw JM.
Opublikowane w: Front Physiol., 2021, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.644837

Contractile pericytes determine the direction of blood flow at capillary junctions

Autorzy: Gonzales AL, Klug NR, Moshkforoush A, Lee JC, Lee FK, Shui B, Tsoukias NM, Kotlikoff MI, Hill-Eubanks D, Nelson MT
Opublikowane w: PNAS, 2021, ISSN 1091-6490
Wydawca: PNAS
DOI: 10.1073/pnas.1922755117

Diagnosing vascular cognitive impairment: Current challenges and future perspectives

Autorzy: J Matthijs Biesbroek, Geert Jan Biessels
Opublikowane w: International Journal of Stroke, 2021, ISSN 0271-678X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/17474930211073387

Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank

Autorzy: Malik, Rainer; Georgakis, Marios K.; Neitzel, Julia; Rannikmäe, Kristiina; Ewers, Michael; Seshadri, Sudha; Sudlow, Cathie L.M.; Dichgans, Martin
Opublikowane w: Alzheimers Dement, Numer 17(9), 2021, Strona(/y) 1422-1431, ISSN 1552-5279
Wydawca: Alzheimer's Association
DOI: 10.1002/alz.12320

Arterial CO2 pressure changes during hypercapnia are associated with changes in brain parenchymal volume

Autorzy: Lisa A. van der Kleij, Jill B. De Vis, Jeroen de Bresser, Jeroen Hendrikse, Jeroen C. W. Siero
Opublikowane w: European Radiology Experimental, Numer 4/1, 2020, ISSN 2509-9280
Wydawca: Springer Nature
DOI: 10.1186/s41747-020-0144-z

Cerebral Amyloid Angiopathy: Still a Syndromal Diagnosis.

Autorzy: Biessels GJ
Opublikowane w: Stroke, 2020, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.120.032703

Strain Tensor Imaging: Cardiac-induced brain tissue deformation in humans quantified with high-field MRI

Autorzy: Jacob-JanSloots,Geert JanBiessels,Albertode Luca, Jaco J.M.Zwanenburg
Opublikowane w: NeuroImage, 2021, ISSN 1053-8119
Wydawca: Academic Press
DOI: 10.1016/j.neuroimage.2021.118078

Brain network reorganisation and spatiallesion distribution in systemic lupuserythematosus

Autorzy: Valdés Hernández MDC, Smith K, Bastin ME, Nicole Amft E, Ralston SH, Wardlaw JM, Wiseman SJ
Opublikowane w: Lupus, 2021, ISSN 2158-2440
Wydawca: SAGE Publications Inc.
DOI: 10.1177/0961203320979045

Cognitive ability, education and socioeconomic status in childhood and risk of post-stroke depression in later life: A systematic review and meta-analysis

Autorzy: Ellen V. Backhouse, Caroline A. McHutchison, Vera Cvoro, Susan D. Shenkin, Joanna M. Wardlaw
Opublikowane w: PLOS ONE, Numer 13/7, 2018, Strona(/y) e0200525, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0200525

Prognostic Significance of Blood Pressure Variability on Beat-to-Beat Monitoring After Transient Ischemic Attack and Stroke

Autorzy: Alastair J.S. Webb, Sara Mazzucco, Linxin Li, Peter M. Rothwell
Opublikowane w: Stroke, Numer 49/1, 2018, Strona(/y) 62-67, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/STROKEAHA.117.019107

Time course of blood pressure control prior to lacunar TIA and stroke

Autorzy: Linxin Li, Sarah J.V. Welch, Sergei A. Gutnikov, Ziyah Mehta, Peter M. Rothwell
Opublikowane w: Neurology, Numer 90/20, 2018, Strona(/y) e1732-e1741, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/WNL.0000000000005526

Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review

Autorzy: Kui Kai Lau, Caroline E. Lovelock, Linxin Li, Michela Simoni, Sergei Gutnikov, Wilhelm Küker, Henry Ka Fung Mak, Peter M. Rothwell
Opublikowane w: Stroke, Numer 49/6, 2018, Strona(/y) 1434-1442, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/STROKEAHA.117.020104

Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging

Autorzy: Caroline M.J. Loos, Stephen D.J. Makin, Julie Staals, Martin S. Dennis, Robert J. van Oostenbrugge, Joanna M. Wardlaw
Opublikowane w: Stroke, Numer 49/5, 2018, Strona(/y) 1183-1188, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/STROKEAHA.117.020495

Vascular reactivity in small cerebral perforating arteries with 7 T phase contrast MRI – A proof of concept study

Autorzy: Lennart J. Geurts, Alex A. Bhogal, Jeroen C.W. Siero, Peter R. Luijten, Geert Jan Biessels, Jaco J.M. Zwanenburg
Opublikowane w: NeuroImage, Numer 172, 2018, Strona(/y) 470-477, ISSN 1053-8119
Wydawca: Academic Press
DOI: 10.1016/j.neuroimage.2018.01.055

The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke

Autorzy: Stephen DJ Makin, Fergus N Doubal, Terence J Quinn, Philip MW Bath, Martin S Dennis, Joanna M Wardlaw
Opublikowane w: European Stroke Journal, Numer 3/1, 2017, Strona(/y) 66-73, ISSN 2396-9873
Wydawca: SAGE Journals
DOI: 10.1177/2396987317728854

Age-Specific Associations of Renal Impairment With Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease in Transient Ischemic Attack and Stroke

Autorzy: Bian Liu, Kui Kai Lau, Linxin Li, Caroline Lovelock, Ming Liu, Wilhelm Kuker, Peter M. Rothwell
Opublikowane w: Stroke, Numer 49/4, 2018, Strona(/y) 899-904, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/STROKEAHA.117.019650

Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke

Autorzy: Caroline A McHutchison, Vera Cvoro, Stephen Makin, Francesca M Chappell, Kirsten Shuler, Joanna M Wardlaw
Opublikowane w: Journal of Neurology, Neurosurgery & Psychiatry, Numer 436-443, 2018, Strona(/y) jnnp-2018-319134, ISSN 0022-3050
Wydawca: BMJ Publishing Group
DOI: 10.1136/jnnp-2018-319134

Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow

Autorzy: Yulu Shi, Michael J Thrippleton, Gordon W Blair, David A Dickie, Ian Marshall, Iona Hamilton, Fergus N Doubal, Francesca Chappell, Joanna M Wardlaw
Opublikowane w: Journal of Cerebral Blood Flow & Metabolism, 2018, Strona(/y) 0271678X1880395, ISSN 0271-678X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x18803956

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Autorzy: Ganesh Chauhan, Hieab H.H. Adams, Claudia L. Satizabal, Joshua C. Bis, Alexander Teumer, Muralidharan Sargurupremraj, Edith Hofer, Stella Trompet, Saima Hilal, Albert Vernon Smith, Xueqiu Jian, Rainer Malik, Matthew Traylor, Sara L. Pulit, Philippe Amouyel, Bernard Mazoyer, Yi-Cheng Zhu, Sara Kaffashian, Sabrina Schilling, Gary W. Beecham, Thomas J. Montine, Gerard D. Schellenberg, Olafur Kjartans
Opublikowane w: Neurology, Numer 92/5, 2019, Strona(/y) e486-e503, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000006851

MRI measurement of blood-brain barrier leakage: minding the gaps

Autorzy: Michael Jonathan Thrippleton
Opublikowane w: The Journal of Physiology, Numer 597/3, 2019, Strona(/y) 667-668, ISSN 0022-3751
Wydawca: Blackwell Publishing Inc.
DOI: 10.1113/jp277425

Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review

Autorzy: Yulu Shi, Michael J. Thrippleton, Ian Marshall, Joanna M. Wardlaw
Opublikowane w: Clinical Science, Numer 132/1, 2018, Strona(/y) 157-171, ISSN 0143-5221
Wydawca: Portland Press, Ltd.
DOI: 10.1042/cs20171280

Cerebrovascular reactivity measurement in cerebral small vessel disease: Rationale and reproducibility of a protocol for MRI acquisition and image processing

Autorzy: Michael J Thrippleton, Yulu Shi, Gordon Blair, Iona Hamilton, Gordon Waiter, Christian Schwarzbauer, Cyril Pernet, Peter JD Andrews, Ian Marshall, Fergus Doubal, Joanna M Wardlaw
Opublikowane w: International Journal of Stroke, Numer 13/2, 2017, Strona(/y) 195-206, ISSN 1747-4930
Wydawca: Blackwell
DOI: 10.1177/1747493017730740

A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology

Autorzy: Catherine A Humphreys, Maurits A Jansen, Susana Muñoz Maniega, Víctor González-Castro, Cyril Pernet, Ian J Deary, Rustam Al-Shahi Salman, Joanna M Wardlaw, Colin Smith
Opublikowane w: International Journal of Stroke, 2018, Strona(/y) 174749301879996, ISSN 1747-4930
Wydawca: Blackwell
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Age and sex-specific associations of carotid pulsatility with small vessel disease burden in transient ischemic attack and ischemic stroke

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