Rezultaty
Our goal is also to work on European guidelines for UM patient management based on what is available alreday thourgh the UK guidelines They will include any additional data or recommendations from the UM Cure 2020 project and rely on the expertise of clinicians from the four European referral centres involved in the project Our objective is indeed to make those Europeanwide and applicable to any caregiver who could have to manage and treat a UM patientAt M60 these guidelines will be provided with a description of their dissemination status
Kick-off meetingAt M2 after the kick-off meeting for the project, a report will be produced which will include the detailed agenda and the minutes of the meeting, as a record of the efficient launch of the project.
Establishing a collection of approx. 200 metastatic UM samplesOur objective would be to reach approx 200 metastatic UM samples collected along the project with matched primary tissue and blood sample whenever possible At M60 at the end of the project we will produce a report on what we have been able to achieve through the concerted action of the reference centres involved and on what these biosamples have been partly used for in the frame of the project
Release of main UM Cure 2020 communication toolsThe main communication tools for the project, namely the website, social media platforms and UM Cure 2020 Consent Card, will be set-up at project start, for a release at M4. A report at M4 will describe such tools and confirm their availability.
Agreement on minimum dataset for all currently banked UM biosamplesThe aim of this deliverable is to share the information currently collected for UM patients and samples across the reference centres, in order to agree on a common minimal set of data that should be available for all UM samples. This precedes the harmonisation efforts among centres which is absolutely necessary to build the common virtual biobank. The common minimal set will be represented by an Excel file with one column per field to be included in the database, and an attached report with description of the work.
Status of prospective collection and use of collected biosamplesD1.3 will consist in a report on the status at M36 of recruitment of prospective UM biosamples under the project. In addition, the status of overall samples available through the network will be included, together with a summary of how these biosamples have been used so far for WP3 and WP4.
Publikacje
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Maria Luisa Cayuela, Kathleen B. M. Claes, Miguel Godinho Ferreira, Catarina Martins Henriques, Fredericus van Eeden, Máté Varga, Jeroen Vierstraete, Maria Caterina Mione
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Frontiers in Cell and Developmental Biology, Numer 6, 2019, ISSN 2296-634X
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Frontiers Media SA
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10.3389/fcell.2018.00178
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Investigative Ophthalmology & Visual Science, 2022, ISSN 0146-0404
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Association for Research in Vision and Ophthalmology
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10.1167/iovs.63.13.14
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Jeremy Bigot, Ana I Lalanne, Francesca Lucibello, Paul Gueguen, Alexandre Houy, Stephane Dayot, Olivier Ganier, Jules Gilet, Jimena Tosello, Fariba Nemati, Gaelle Pierron, Joshua J Waterfall, Raymond Barnhill, Sophie Gardrat, Sophie Piperno-Neumann, Tatiana Popova, Vanessa Masson, Damarys Loew, Pascale Mariani, Nathalie Cassoux, Sebastian Amigorena, Manuel Rodrigues, Samar Alsafadi, Marc-Henri Ste
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Cancer Discovery, 2021, Strona(/y) candisc.0555.2020, ISSN 2159-8274
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American Association for Cancer Research Inc.
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10.1158/2159-8290.cd-20-0555
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Lenha Mobuchon, Anne-Céline Derrien, Alexandre Houy, Thibault Verrier, Gaëlle Pierron, Nathalie Cassoux, Maud Milder, Jean-François Deleuze, Anne Boland, Ghislaine Scelo, Géraldine Cancel-Tassin, Olivier Cussenot, Manuel Rodrigues, Josselin Noirel, Mitchell J Machiela, Marc-Henri Stern
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JNCI: Journal of the National Cancer Institute, 2021, ISSN 0027-8874
Wydawca:
Oxford University Press
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10.1093/jnci/djab167
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Cancers; Volume 14; Numer 13; Pages: 3186, Numer 1, 2022, ISSN 2072-6694
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Multidisciplinary Digital Publishing Institute (MDPI)
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10.3390/cancers14133186
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Nathalie Dhomen, Piyushkumar A. Mundra, Richard Marais
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British Journal of Cancer, 2021, ISSN 0007-0920
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Nature Publishing Group
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10.1038/s41416-021-01343-8
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Arwin Groenewoud, Jie Yin, B. Ewa Snaar-Jagalska
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Journal of Visualized Experiments, Numer 175, 2021, ISSN 1940-087X
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MYJoVE Corporation
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10.3791/62356
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Samar Alsafadi, Stephane Dayot, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Michele Cornella, Michel Wassef, Joshua J. Waterfall, Erik Lehnert, Sergio Roman-Roman, Marc-Henri Stern, Tatiana Popova
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Oncogene, Numer 40/1, 2021, Strona(/y) 85-96, ISSN 0950-9232
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Nature Publishing Group
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Human Mutation, Numer 41/12, 2020, Strona(/y) 2205-2216, ISSN 1059-7794
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John Wiley & Sons Inc.
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10.1002/humu.24111
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Christine Canbezdi, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Tatiana Popova, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
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Computational and Structural Biotechnology Journal, Numer 19, 2021, Strona(/y) 1361-1370, ISSN 2001-0370
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Elsevier
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10.1016/j.csbj.2021.02.012
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BMC Cancer, Numer 21/1, 2021, ISSN 1471-2407
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International Journal of Molecular Sciences, Numer 21/19, 2020, Strona(/y) 7172, ISSN 1422-0067
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Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
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Nature Publishing Group
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Mehmet Dogrusöz, Martine J. Jager
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Acta Ophthalmologica, 2017, ISSN 1755-375X
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Cancers, Numer 11/7, 2019, Strona(/y) 979, ISSN 2072-6694
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Multidisciplinary Digital Publishing Institute (MDPI)
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Cancers, Numer 11/7, 2019, Strona(/y) 1019, ISSN 2072-6694
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Manuel Rodrigues, Leanne de Koning, Sarah Coupland, Aart Jochemsen, Richard Marais, Marc-Henri Stern, André Valente, Raymond Barnhill, Nathalie Cassoux, Andrew Evans, Iain Galloway, Martine Jager, Ellen Kapiteijn, Bozena Romanowska-Dixon, Bettina Ryll, Sergio Roman-Roman, Sophie Piperno-Neumann
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Cancers, Numer 11/7, 2019, Strona(/y) 1032, ISSN 2072-6694
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Cancers, Numer 11/8, 2019, Strona(/y) 1132, ISSN 2072-6694
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Cancers, Numer 11/8, 2019, Strona(/y) 1102, ISSN 2072-6694
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Mehmet Dogrusöz, Andrea Ruschel Trasel, Jinfeng Cao, Selҫuk Ҫolak, Sake I. van Pelt, Wilma G. M. Kroes, Amina F. A. S. Teunisse, Samar Alsafadi, Sjoerd G. van Duinen, Gregorius P. M. Luyten, Pieter A. van der Velden, Adriana Amaro, Ulrich Pfeffer, Aart G. Jochemsen, Martine J. Jager
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Cancers, Numer 11/8, 2019, Strona(/y) 1104, ISSN 2072-6694
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Cancers, Numer 11/8, 2019, Strona(/y) 1127, ISSN 2072-6694
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10.3390/cancers11081127
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Annemijn P. A. Wierenga, Gülçin Gezgin, Els van Beelen, Michael Eikmans, Marijke Spruyt-Gerritse, Niels J. Brouwer, Mieke Versluis, Robert M. Verdijk, Sjoerd G. van Duinen, Marina Marinkovic, Gregorius P. M. Luyten, Martine J. Jager
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Cancers, Numer 11/8, 2019, Strona(/y) 1202, ISSN 2072-6694
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Multidisciplinary Digital Publishing Institute (MDPI)
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10.3390/cancers11081202
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Opublikowane w:
Developmental Biology, 2019, ISSN 0012-1606
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Academic Press
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10.1016/j.ydbio.2019.04.005
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Annemijn P. A. Wierenga, Jinfeng Cao, Henk Mouthaan, Christiaan van Weeghel, Robert M. Verdijk, Sjoerd G. van Duinen, Wilma G. M. Kroes, Mehmet Dogrusöz, Marina Marinkovic, Sjoerd S. H. van der Burg, Gregorius P. M. Luyten, Martine J. Jager
Opublikowane w:
Investigative Opthalmology & Visual Science, Numer 60/14, 2019, Strona(/y) 4740, ISSN 1552-5783
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The Association for Research in Vision and Ophthalmology (ARVO)
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European Journal of Cancer, Numer 126, 2020, Strona(/y) 93-103, ISSN 0959-8049
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Martine J. Jager, Carol L. Shields, Colleen M. Cebulla, Mohamed H. Abdel-Rahman, Hans E. Grossniklaus, Marc-Henri Stern, Richard D. Carvajal, Rubens N. Belfort, Renbing Jia, Jerry A. Shields, Bertil E. Damato
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Nature Reviews Disease Primers, Numer 6/1, 2020, ISSN 2056-676X
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Acta Ophthalmologica, Numer 94, 2016, ISSN 1755-375X
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European Journal of Cancer, Numer 61, 2016, Strona(/y) S204-S205, ISSN 0959-8049
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1st Italian Zebrafish Meeting, 2-3 February 2017, 2017
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Universita degli studi di Padova
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EACR-AACR-SIC Special Conference 2017: The Challenges of Optimizing Immuno- and Targeted Therapies: From Cancer Biology to the Clinic, 2017
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European Cancer Organisaton (ECCO)
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