Magnetic Solid Lipid Nanoparticles as a Multifunctional Platform against Glioblastoma Multiforme

Informacje na temat projektu

SLaMM

Identyfikator umowy o grant: 709613

DOI

10.3030/709613

Projekt został zamknięty

Data podpisania przez KE 19 Grudnia 2016

Data rozpoczęcia 1 Marca 2017

Data zakończenia 31 Grudnia 2022

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 499 997,42

Wkład UE

€ 1 499 997,42

Koordynowany przez

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (23)

Porous Optically Transparent Cellulose Acetate Scaffolds for Biomimetic Blood-Brain Barrierin vitro Models

Autorzy: Attilio Marino, Micol Baronio, Umberto Buratti, Elisa Mele, Gianni Ciofani
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 9, 2021, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2021.630063

Ultrasound-responsive nutlin-loaded nanoparticles for combined chemotherapy and piezoelectric treatment of glioblastoma cells.

Autorzy: Carlotta Pucci; Attilio Marino; Özlem Şen; Daniele De Pasquale; Martina Bartolucci; Nerea Iturrioz-Rodríguez; Nicoletta di Leo; Giuseppe de Vito; Doriana Debellis; Andrea Petretto; Gianni Ciofani
Opublikowane w: Acta Biomaterialia, Numer 139, 2022, Strona(/y) 218-236, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2021.04.005

Combining confocal microscopy, dSTORM, and mass spectroscopy to unveil the evolution of the protein corona associated with nanostructured lipid carriers during blood-brain barrier crossing

Autorzy: Matteo Battaglini, Natalia Feiner, Christos Tapeinos, Daniele De Pasquale, Carlotta Pucci, Attilio Marino, Martina Bartolucci, Andrea Petretto, Lorenzo Albertazzi, Gianni Ciofani
Opublikowane w: Nanoscale, Numer 20403364, 2022, Strona(/y) 13292-13307, ISSN 2040-3364
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2nr00484d

Drug-loaded lipid magnetic nanoparticles for combined local hyperthermia and chemotherapy against glioblastoma multiforme

Autorzy: Beola Lilianne, Iturrioz-Rodríguez Nera, Pucci Carlotta, Bertorelli Rosalia, Ciofani Gianni
Opublikowane w: ACS Nano, Numer 17(18), 2023, Strona(/y) 18441-18455, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.3c06085

Nanotechnology‐Based Strategies to Evaluate and Counteract Cancer Metastasis and Neoangiogenesis

Autorzy: Özlem Şen, Melis Emanet, Gianni Ciofani
Opublikowane w: Advanced Healthcare Materials, Numer 10/10, 2021, Strona(/y) 2002163, ISSN 2192-2640
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202002163

Modulation of anti-angiogenic activity using ultrasound-activated nutlin-loaded piezoelectric nanovectors

Autorzy: Ozlem Sen, Attilio Marino, Carlotta Pucci, Gianni Ciofani
Opublikowane w: Materials Today Bio, Numer 13, 2022, Strona(/y) 100196, ISSN 2590-0064
Wydawca: Elsevier
DOI: 10.1016/j.mtbio.2021.100196

Magnetic Nanotransducers in Biomedicine

Autorzy: Agostina Grillone, Gianni Ciofani
Opublikowane w: Chemistry - A European Journal, Numer 23/64, 2017, Strona(/y) 16109-16114, ISSN 0947-6539
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201703660

Smart Materials Meet Multifunctional Biomedical Devices: Current and Prospective Implications for Nanomedicine

Autorzy: Giada Graziana Genchi, Attilio Marino, Christos Tapeinos, Gianni Ciofani
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 5, 2017, Strona(/y) 8, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2017.00080

Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

Autorzy: Christos Tapeinos, Matteo Battaglini, Gianni Ciofani
Opublikowane w: Journal of Controlled Release, Numer 264, 2017, Strona(/y) 306-332, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2017.08.033

A 3D Real-Scale, Biomimetic, and Biohybrid Model of the Blood-Brain Barrier Fabricated through Two-Photon Lithography

Autorzy: Attilio Marino, Omar Tricinci, Matteo Battaglini, Carlo Filippeschi, Virgilio Mattoli, Edoardo Sinibaldi, Gianni Ciofani
Opublikowane w: Small, Numer 14/6, 2018, Strona(/y) 1702959, ISSN 1613-6810
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201702959

Stimuli-responsive lipid-based magnetic nanovectors increase apoptosis in glioblastoma cells through synergic intracellular hyperthermia and chemotherapy

Autorzy: Christos Tapeinos, Attilio Marino, Matteo Battaglini, Simone Migliorin, Rosaria Brescia, Alice Scarpellini, César De Julián Fernández, Mirko Prato, Filippo Drago, Gianni Ciofani
Opublikowane w: Nanoscale, Numer 11/1, 2019, Strona(/y) 72-88, ISSN 2040-3364
Wydawca: Royal Society of Chemistry
DOI: 10.1039/C8NR05520C

Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme

Autorzy: Attilio Marino, Enrico Almici, Simone Migliorin, Christos Tapeinos, Matteo Battaglini, Valentina Cappello, Marco Marchetti, Giuseppe de Vito, Riccardo Cicchi, Francesco Saverio Pavone, Gianni Ciofani
Opublikowane w: Journal of Colloid and Interface Science, Numer 538, 2019, Strona(/y) 449-461, ISSN 0021-9797
Wydawca: Academic Press
DOI: 10.1016/j.jcis.2018.12.014

Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment

Autorzy: Agostina Grillone, Matteo Battaglini, Stefania Moscato, Letizia Mattii, César de Julián Fernández, Alice Scarpellini, Mario Giorgi, Edoardo Sinibaldi, Gianni Ciofani
Opublikowane w: Nanomedicine, Numer 14/6, 2019, Strona(/y) 727-752, ISSN 1743-5889
Wydawca: Future Medicine Ltd.
DOI: 10.2217/nnm-2018-0436

Nanostructured carriers as innovative tools for cancer diagnosis and therapy

Autorzy: Chiara Martinelli, Carlotta Pucci, Gianni Ciofani
Opublikowane w: APL Bioengineering, Numer 3/1, 2019, Strona(/y) 011502, ISSN 2473-2877
Wydawca: AIP
DOI: 10.1063/1.5079943

Cell Membrane‐Coated Magnetic Nanocubes with a Homotypic Targeting Ability Increase Intracellular Temperature due to ROS Scavenging and Act as a Versatile Theranostic System for Glioblastoma Multiforme

Autorzy: Christos Tapeinos, Francesca Tomatis, Matteo Battaglini, Aitor Larrañaga, Attilio Marino, Iker Aguirrezabal Telleria, Makis Angelakeris, Doriana Debellis, Filippo Drago, Francesca Brero, Paolo Arosio, Alessandro Lascialfari, Andrea Petretto, Edoardo Sinibaldi, Gianni Ciofani
Opublikowane w: Advanced Healthcare Materials, Numer 8(18), 2019, Strona(/y) 1900612, ISSN 2192-2640
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201900612

Innovative approaches for cancer treatment: current perspectives and new challenges

Autorzy: Carlotta Pucci, Chiara Martinelli, Gianni Ciofani
Opublikowane w: ecancermedicalscience, Numer 13, 2019, Strona(/y) 961, ISSN 1754-6605
Wydawca: eCancer Global Foundation
DOI: 10.3332/ecancer.2019.961

Multifunctional temozolomide-loaded lipid superparamagnetic nanovectors: dual targeting and disintegration of glioblastoma spheroids by synergic chemotherapy and hyperthermia treatment

Autorzy: Attilio Marino, Alice Camponovo, Andrea Degl'Innocenti, Martina Bartolucci, Christos Tapeinos, Chiara Martinelli, Daniele De Pasquale, Francesca Santoro, Valentina Mollo, Satoshi Arai, Madoka Suzuki, Yoshie Harada, Andrea Petretto, Gianni Ciofani
Opublikowane w: Nanoscale, Numer 11/44, 2019, Strona(/y) 21227-21248, ISSN 2040-3364
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c9nr07976a

Genetic Hallmarks and Heterogeneity of Glioblastoma in the Single‐Cell Omics Era

Autorzy: Andrea Degl'Innocenti, Nicoletta di Leo, Gianni Ciofani
Opublikowane w: Advanced Therapeutics, Numer 3/1, 2019, Strona(/y) 1900152, ISSN 2366-3987
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adtp.201900152

What does the future hold for chemotherapy with the use of lipid-based nanocarriers?

Autorzy: Carlotta Pucci, Chiara Martinelli, Gianni Ciofani
Opublikowane w: Future Oncology, Numer 16/5, 2020, Strona(/y) 81-84, ISSN 1479-6694
Wydawca: Future Medicine Ltd.
DOI: 10.2217/fon-2019-0767

Editorial: Advanced Theranostic Nanomedicine in Oncology

Autorzy: Christos Tapeinos, Attilio Marino, Gianni Ciofani
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 8, 2020, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2020.00142

Homotypic targeting and drug delivery in glioblastoma cells through cell membrane-coated boron nitride nanotubes

Autorzy: Daniele De Pasquale, Attilio Marino, Christos Tapeinos, Carlotta Pucci, Silvia Rocchiccioli, Elena Michelucci, Francesco Finamore, Liam McDonnell, Alice Scarpellini, Simone Lauciello, Mirko Prato, Aitor Larrañaga, Filippo Drago, Gianni Ciofani
Opublikowane w: Materials & Design, Numer 192, 2020, Strona(/y) 108742, ISSN 0264-1275
Wydawca: Elsevier BV
DOI: 10.1016/j.matdes.2020.108742

Hybrid Magnetic Nanovectors Promote Selective Glioblastoma Cell Death through a Combined Effect of Lysosomal Membrane Permeabilization and Chemotherapy

Autorzy: Carlotta Pucci, Daniele De Pasquale, Attilio Marino, Chiara Martinelli, Simone Lauciello, Gianni Ciofani
Opublikowane w: ACS Applied Materials & Interfaces, Numer 12/26, 2020, Strona(/y) 29037-29055, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/acsami.0c05556

Lipid‐Based Nanocarriers for The Treatment of Glioblastoma

Autorzy: Nerea Iturrioz-Rodríguez, Rosalia Bertorelli, Gianni Ciofani
Opublikowane w: Advanced NanoBiomed Research, Numer 1/2, 2021, Strona(/y) 2000054, ISSN 2699-9307
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/anbr.202000054

Prawa własności intelektualnej

Patent (1)

CELL CO-CULTURE SYSTEM AND METHOD

Numer wniosku/publikacji: 20 796929
Data: 2020-10-06
Wnioskodawca/wnioskodawcy: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA