Understanding the physical biology of adult blood stem cells

Rezultaty

Participation in the Open Research Data Pilot

Publikacje

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Autorzy: Mairi S. Shepherd, Juan Li, Nicola K. Wilson, Caroline A. Oedekoven, Jiangbing Li, Miriam Belmonte, Juergen Fink, Janine C. M. Prick, Dean C. Pask, Tina L. Hamilton, Dirk Loeffler, Anjana Rao, Timm Schröder, Berthold Göttgens, Anthony R. Green, David G. Kent
Opublikowane w: BLOOD, 2018, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2017-12-821066

Identification and characterization of in vitro expanded hematopoietic stem cells

Autorzy: James Che; Daniel Bode; Iwo Kucinski; Alyssa H Cull; Fiona Bain; Hans J Becker; Maria Jassinskaja; Melania Barile; Grace Boyd; Miriam Belmonte; Andy G X Zeng; Kyomi J Igarashi; Juan Rubio-Lara; Mairi S Shepherd; Anna Clay; John E Dick; Adam C Wilkinson; Hiromitsu Nakauchi; Satoshi Yamazaki; Berthold Göttgens; David G Kent
Opublikowane w: EMBO Reports, 2022, ISSN 1469-221X
Wydawca: Nature Publishing Group
DOI: 10.15252/embr.202255502

A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice

Autorzy: Joakim S. Dahlin, Fiona K. Hamey, Blanca Pijuan-Sala, Mairi Shepherd, Winnie W. Y. Lau, Sonia Nestorowa, Caleb Weinreb, Samuel Wolock, Rebecca Hannah, Evangelia Diamanti, David G. Kent, Berthold Göttgens, Nicola K. Wilson
Opublikowane w: BLOOD, 2018, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2017-12-821413

Somatic mutation landscapes at single-molecule resolution

Autorzy: Federico Abascal, Luke M. R. Harvey, Emily Mitchell, Andrew R. J. Lawson, Stefanie V. Lensing, Peter Ellis, Andrew J. C. Russell, Raul E. Alcantara, Adrian Baez-Ortega, Yichen Wang, Eugene Jing Kwa, Henry Lee-Six, Alex Cagan, Tim H. H. Coorens, Michael Spencer Chapman, Sigurgeir Olafsson, Steven Leonard, David Jones, Heather E. Machado, Megan Davies, Nina F. Øbro, Krishnaa T. Mahubani, Kieren All
Opublikowane w: Nature, 2021, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-021-03477-4

Clonal dynamics of haematopoiesis across the human lifespan

Autorzy: Emily Mitchell, Michael Spencer Chapman, Nicholas Williams, Kevin J. Dawson, Nicole Mende, Emily F. Calderbank, Hyunchul Jung, Thomas Mitchell, Tim H. H. Coorens, David H. Spencer, Heather Machado, Henry Lee-Six, Megan Davies, Daniel Hayler, Margarete A. Fabre, Krishnaa Mahbubani, Federico Abascal, Alex Cagan, George S. Vassiliou, Joanna Baxter, Inigo Martincorena, Michael R. Stratton, David G. Ke
Opublikowane w: Nature, 2022, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-022-04786-y

Population dynamics of normal human blood inferred from somatic mutations

Autorzy: Henry Lee-Six, Nina Friesgaard Øbro, Mairi S. Shepherd, Sebastian Grossmann, Kevin Dawson, Miriam Belmonte, Robert J. Osborne, Brian J. P. Huntly, Inigo Martincorena, Elizabeth Anderson, Laura O’Neill, Michael R. Stratton, Elisa Laurenti, Anthony R. Green, David G. Kent, Peter J. Campbell
Opublikowane w: Nature, Numer 561/7724, 2018, Strona(/y) 473-478, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-018-0497-0

A track of the clones: new developments in cellular barcoding

Autorzy: Anne-Marie Lyne, David G. Kent, Elisa Laurenti, Kerstin Cornils, Ingmar Glauche, Leïla Perié
Opublikowane w: Experimental Hematology, Numer 68, 2018, Strona(/y) 15-20, ISSN 0301-472X
Wydawca: Elsevier BV
DOI: 10.1016/j.exphem.2018.11.005

Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures

Autorzy: Caroline A. Oedekoven; Miriam Belmonte; Daniel Bode; Fiona K. Hamey; Mairi S. Shepherd; James Lok Chi Che; Grace Boyd; Craig McDonald; Serena Belluschi; Evangelia Diamanti; Hugo P. Bastos; Katherine S. Bridge; Berthold Göttgens; Elisa Laurenti; David G. Kent
Opublikowane w: Stem Cell Reports, 2021, ISSN 2213-6711
Wydawca: Cell Press
DOI: 10.1016/j.stemcr.2021.04.002

HOXA9 has the hallmarks of a biological switch with implications in blood cancers

Autorzy: Laure Talarmain, Matthew A. Clarke, David Shorthouse, Lilia Cabrera-Cosme, David G. Kent, Jasmin Fisher & Benjamin A. Hall
Opublikowane w: Nature Communications, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-33189-w

Exploiting Single-Cell Tools in Gene and Cell Therapy

Autorzy: Daniel Bode; Alyssa H. Cull; Juan A. Rubio-Lara; and David G. Kent
Opublikowane w: Frontiers in Immunology, 2021, ISSN 1664-3224
Wydawca: Frontiers
DOI: 10.3389/fimmu.2021.702636

Protocol to maintain single functional mouse hematopoietic stem cells in vitro without cell division

Autorzy: Miriam Belmonte; David G Kent
Opublikowane w: STAR Protocols, 2021, ISSN 2666-1667
Wydawca: Cell Press
DOI: 10.1016/j.xpro.2021.100927

Diverse mutational landscapes in human lymphocytes

Autorzy: Heather E. Machado, Emily Mitchell, Nina F. Øbro, Kirsten Kübler, Megan Davies, Daniel Leongamornlert, Alyssa Cull, Francesco Maura, Mathijs A. Sanders, Alex T. J. Cagan, Craig McDonald, Miriam Belmonte, Mairi S. Shepherd, Felipe A. Vieira Braga, Robert J. Osborne, Krishnaa Mahbubani, Iñigo Martincorena, Elisa Laurenti, Anthony R. Green, Gad Getz, Paz Polak, Kourosh Saeb-Parsy, Daniel J. Hodson
Opublikowane w: Nature, 2022, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-022-05072-7

Rezultaty

Publikacje

Udostępnij tę stronę

Pobierz