Rezultaty Other (3) Participation in European Researchers' Night 1 For presenting the A4B ITN in public it A4B participants will participate in European Researchers Nights Publication of advertising for open ESR positions For acquiring the ESR advertising for open positions will be published in different media. Participation in European Researchers' Night 2 For presenting the A4B ITN in public it A4B participants will participate in European Researchers Nights Websites, patent fillings, videos etc. (1) Project Website Quotations about the preparation of the Website and their maintenance will be defined and applied. The content of the Website will defined at the kick-off meeting. Publikacje Peer reviewed articles (34) Glycoform analysis of intact erythropoietin by MALDI FT-ICR mass spectrometry Autorzy: Steffen Lippold, Raashina Thavarajah, Dietmar Reusch, Manfred Wuhrer, Simone Nicolardi Opublikowane w: Analytica chimica acta, 2021, ISSN 0003-2670 Wydawca: Elsevier BV DOI: 10.1016/j.aca.2021.339084 Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry Autorzy: Steffen Lippold , Alexander Knaupp , Arnoud H de Ru , Rayman T N Tjokrodirijo , Peter A van Veelen, Erwin van Puijenbroek, Steven W de Taeye, Dietmar Reusch, Gestur Vidarsson, Manfred Wuhrer, Tilman Schlothauer, David Falck Opublikowane w: mAbs, 2021, ISSN 1942-0870 Wydawca: Landes Bioscience DOI: 10.1080/19420862.2021.1982847 FLASHIda enables intelligent data acquisition for top–down proteomics to boost proteoform identification counts Autorzy: Kyowon Jeong, Maša Babović, Vladimir Gorshkov, Jihyung Kim, Ole N. Jensen, Oliver Kohlbacher Opublikowane w: Nature Communications, 2022, ISSN 2041-1723 Wydawca: Nature Publishing Group DOI: 10.1038/s41467-022-31922-z Intact and subunit-specific analysis of bispecific antibodies by sheathless CE-MS Autorzy: Christoph Gstöttner, Simone Nicolardi, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Elena Domínguez-Vega Opublikowane w: Analytica chimica acta, 2020, ISSN 0003-2670 Wydawca: Elsevier BV DOI: 10.1016/j.aca.2020.07.069 Change of charge variant composition of trastuzumab upon stressing at physiological conditions Autorzy: Baubek Spanov, Oladapo Olaleye, Nico Lingg, Arthur E.H. Bentlage, Natalia Govorukhina, Jos Hermans, Nico van de Merbel, Gestur Vidarsson, Alois Jungbauer, Rainer Bischoff Opublikowane w: Journal of Chromatography A, Numer 1655, 2021, Strona(/y) 462506, ISSN 0021-9673 Wydawca: Elsevier BV DOI: 10.1016/j.chroma.2021.462506 Continuous capture of recombinant antibodies by ZnCl2 precipitation without polyethylene glycol Autorzy: Gregory Dutra, Daniel Komuczki, Alois Jungbauer, Peter Satzer Opublikowane w: Engineering in Life Sciences, 2020, ISSN 1618-0240 Wydawca: John Wiley & Sons Ltd. DOI: 10.1002/elsc.201900160 Structural and Functional Characterization of SARS-CoV-2 RBD Domains Produced in Mammalian Cells Autorzy: Christoph Gstöttner, Tao Zhang, Anja Resemann, Sophia Ruben, Stuart Pengelley, Detlev Suckau, Tim Welsink, Manfred Wuhrer, Elena Domínguez-Vega Opublikowane w: Analytical Chemistry, 2021, ISSN 0003-2700 Wydawca: American Chemical Society DOI: 10.1021/acs.analchem.1c00893 Structural and In Vitro Functional Comparability Analysis of Altebrel™, a Proposed Etanercept Biosimilar: Focus on Primary Sequence and Glycosylation Autorzy: Ramin Fazel, Yudong Guan, Behrouz Vaziri, Christoph Krisp, Laura Heikaus, Amirhossein Saadati, Siti Nurul Hidayah, Manasi Gaikwad, Hartmut Schlüter Opublikowane w: Pharmaceuticals (Basel), 2019, ISSN 1424-8247 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ph12010014 Semiautomated glycoproteomics data analysis workflow for maximized glycopeptide identification and reliable quantification Autorzy: Steffen Lippold, Arnoud H de Ru, Jan Nouta, Peter A van Veelen, Magnus Palmblad, Manfred Wuhrer, Noortje de Haan Opublikowane w: Beilstein journal of organic chemistry, 2020, ISSN 1860-5397 Wydawca: Beilstein-Institut DOI: 10.3762/bjoc.16.253 Serum and Plasma Immunoglobulin G Fc N-Glycosylation Is Stable during Storage Autorzy: Manuela Amez Martín, Manfred Wuhrer, David Falck Opublikowane w: Journal of Proteome Research, 2021, ISSN 1535-3893 Wydawca: American Chemical Society DOI: 10.1021/acs.jproteome.1c00148 Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics Autorzy: Oksana Tyshchuk, Christoph Gstöttner, Dennis Funk, Simone Nicolardi, Stefan Frost, Stefan Klostermann, Tim Becker, Elena Jolkver, Felix Schumacher, Claudia Ferrara Koller, Hans Rainer Völger, Manfred Wuhrer, Patrick Bulau, and Michael Mølhøj Opublikowane w: mAbs, 2019, ISSN 1942-0870 Wydawca: Landes Bioscience DOI: 10.1080/19420862.2019.1635865 Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension Autorzy: Emma von Witting, Sarah Lindbo, Magnus Lundqvist, Marit Möller, Andreas Wisniewski, Sara Kanje, Johan Rockberg, Hanna Tegel, Mikael Åstrand, Mathias Uhlen, and Sophia Hober Opublikowane w: Molecular Pharmaceutics, 2021, ISSN 1543-8384 Wydawca: American Chemical Society DOI: 10.1021/acs.molpharmaceut.0c00975 Cysteine Aminoethylation Enables the Site-Specific Glycosylation Analysis of Recombinant Human Erythropoietin using Trypsin Autorzy: Steffen Lippold, Alexander Büttner, Matthew S F Choo, Michaela Hook, Coen J de Jong, Terry Nguyen-Khuong, Markus Haberger, Dietmar Reusch, Manfred Wuhrer, Noortje de Haan Opublikowane w: Analytical chemistry, 2020, ISSN 0003-2700 Wydawca: American Chemical Society DOI: 10.1021/acs.analchem.0c01794 Impact of failure rates, lot definitions and scheduling of upstream processes on the productivity of continuous integrated bioprocesses Autorzy: Peter Satzer, Daniel Komuczki, Magdalena Pappenreiter, Alessandro Luigi Cataldo, Bernhard Sissolak, Alois Jungbauer Opublikowane w: Journal of Chemical Technology & Biotechnology, 2020, ISSN 0268-2575 Wydawca: John Wiley & Sons Inc. DOI: 10.1002/jctb.6648 An Integrated Strategy Reveals Complex Glycosylation of Erythropoietin Using Mass Spectrometry Autorzy: Yudong Guan, Min Zhang, Manasi Gaikwad, Hannah Voss, Ramin Fazel, Samira Ansari, Huali Shen, Jigang Wang, and Hartmut Schlüter Opublikowane w: Journal of proteome research, 2021, ISSN 1535-3893 Wydawca: American Chemical Society DOI: 10.1021/acs.jproteome.1c00221 Immunoglobulin G Glycoprofiles are Unaffected by Common Bottom-Up Sample Processing Autorzy: Manuela Amez-Martín, Manfred Wuhrer, David Falck Opublikowane w: Journal of Proteome Research, 2020, ISSN 1535-3893 Wydawca: American Chemical Society DOI: 10.1021/acs.jproteome.0c00656 Characterization of a novel + 70 Da modification in rhGM-CSF expressed in E. coli using chemical assays in combination with mass spectrometry Autorzy: Magdalena Widgren Sandberg, Jakob Bunkenborg, Stine Thyssen, Martin Villadsen, Thomas Kofoed Opublikowane w: Amino Acids, 2021, ISSN 0939-4451 Wydawca: Springer Verlag DOI: 10.1007/s00726-021-03004-9 Affinity capillary electrophoresis – mass spectrometry as tool to unravel proteoform-specific antibody-receptor interactions Autorzy: Christoph Gstöttner, Michaela Hook, Tony Christopeit, Alexander Knaupp, Tilman Schlothauer, Dietmar Reusch, Markus Haberger, Manfred Wuhrer, Elena Domínguez-Vega Opublikowane w: Analytical Chemistry, 2021, ISSN 0003-2700 Wydawca: American Chemical Society DOI: 10.1021/acs.analchem.1c03560 Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension Autorzy: Emma von Witting, Sarah Lindbo, Magnus Lundqvist, Marit Möller, Andreas Wisniewski, Sara Kanje, Johan Rockberg, Hanna Tegel, Mikael Åstrand, Mathias Uhlén, and Sophia Hober Opublikowane w: Molecular Pharmaceutics, 2021, ISSN 1543-8384 Wydawca: American Chemical Society DOI: 10.1021/acs.molpharmaceut.0c00975 Effect of Trastuzumab-HER2 Complex Formation on Stress-Induced Modifications in the CDRs of Trastuzumab Autorzy: Baubek Spanov, Victoria Aboagye , Oladapo Olaleye, Natalia Govorukhina, Nico C van de Merbel, Rainer Bischoff Opublikowane w: Frontiers in Chemistry, 2022, ISSN 2296-2646 Wydawca: Frontiers Media SA DOI: 10.3389/fchem.2021.794247 FLASHDeconv: Ultrafast, high-quality feature deconvolution for top-down proteomics Autorzy: Kyowon Jeong, Jihyung Kim, Manasi Gaikwad, Siti Nurul Hidayah, Laura Heikaus, Hartmut Schlüter, Oliver Kohlbacher Opublikowane w: Cell Systems, 2020, ISSN 2405-4720 Wydawca: Cell Press DOI: 10.1016/j.cels.2020.01.003 Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry Autorzy: Steffen Lippold, Simone Nicolardi, Elena Domínguez-Vega, Anna-Katharina Heidenreich, Gestur Vidarsson, Dietmar Reusch, Markus Haberger, Manfred Wuhrer, David Falck Opublikowane w: mAbs, Numer 11/7, 2019, Strona(/y) 1191-1196, ISSN 1942-0870 Wydawca: Landes Bioscience DOI: 10.1080/19420862.2019.1636602 Proteoform-Resolved FcɤRIIIa Binding Assay for Fab Glycosylated Monoclonal Antibodies Achieved by Affinity Chromatography Mass Spectrometry of Fc Moieties Autorzy: Steffen Lippold, Simone Nicolardi, Manfred Wuhrer, David Falck Opublikowane w: Frontiers in Chemistry, Numer 7, 2019, Strona(/y) 1-10, ISSN 2296-2646 Wydawca: Frontiers in Chemistry DOI: 10.3389/fchem.2019.00698 Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh resolution MALDI FT-ICR mass spectrometry Autorzy: Christoph Gstöttner, Dietmar Reusch, Markus Haberger, Irina Dragan, Peter van Veelen, David P. A. Kilgour, Yury O. Tsybin, Yuri E.M. van der Burgt, Manfred Wuhrer, Simone Nicolardi Opublikowane w: mAbs, 2019, ISSN 1942-0870 Wydawca: Landes Bioscience DOI: 10.1080/19420862.2019.1682403 Intact protein bioanalysis by liquid chromatography – High-resolution mass spectrometry Autorzy: Peter Bults, Baubek Spanov, Oladapo Olaleye, Nico C. van de Merbel, Rainer Bischoff Opublikowane w: Journal of Chromatography B, Numer 1110-1111, 2019, Strona(/y) 155-167, ISSN 1570-0232 Wydawca: Elsevier BV DOI: 10.1016/j.jchromb.2019.01.032 Structural and In Vitro Functional Comparability Analysis of Altebrel™, a Proposed Etanercept Biosimilar: Focus on Primary Sequence and Glycosylation Autorzy: Ramin Fazel, Yudong Guan, Behrouz Vaziri, Christoph Krisp, Laura Heikaus, Amirhossein Saadati, Siti Nurul Hidayah, Manasi Gaikwad, Hartmut Schlüter Opublikowane w: Pharmaceuticals, Numer 12/1, 2019, Strona(/y) 14, ISSN 1424-8247 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ph12010014 In-situ gradient formation by direct solid addition of buffer components Autorzy: D.Komuczki, N.Lingg, A.Jungbauer, P.Satzer Opublikowane w: Journal of Chromatography A, 2020, ISSN 0021-9673 Wydawca: Elsevier BV DOI: 10.1016/j.chroma.2020.461663 Sheathless CE‐MS as a tool for monitoring exchange efficiency and stability of bispecific antibodies Autorzy: Christoph Gstöttner, Dana L E Vergoossen, Manfred Wuhrer, Maartje G M Huijbers, Elena Domínguez-Vega Opublikowane w: Electrophoresis, 2021, ISSN 0173-0835 Wydawca: John Wiley & Sons Ltd. DOI: 10.1002/elps.202000166 Anion exchange chromatography – Mass spectrometry for monitoring multiple quality attributes of erythropoietin biopharmaceuticals Autorzy: Guusje van Schaick, Christoph Gstöttner, Alexander Büttner, Dietmar Reusch, Manfred Wuhrer, Elena Domínguez-Vega Opublikowane w: Analytica chimica acta, 2021, ISSN 0003-2670 Wydawca: Elsevier BV DOI: 10.1016/j.aca.2020.11.027 Non-Antibody-Based Binders for the Enrichment of Proteins for Analysis by Mass Spectrometry Autorzy: Oladapo Olaleye, Natalia Govorukhina, Nico C van de Merbel, Rainer Bischoff Opublikowane w: Biomolecules, 2021, ISSN 2218-273X Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/biom11121791 Media on-demand: Continuous reconstitution of a chemically defined media directly from solids Autorzy: Daniel Komuczki, Gregory Dutra, Christoph Gstöttner, Elena Dominguez-Vega, Alois Jungbauer, Peter Satzer Opublikowane w: Biotechnology and Bioengineering, 2021, ISSN 0006-3592 Wydawca: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/bit.27738 Enrichment and Liquid Chromatography–Mass Spectrometry Analysis of Trastuzumab and Pertuzumab Using Affimer Reagents Autorzy: Oladapo Olaleye, Baubek Spanov, Robert Ford, Natalia Govorukhina, Nico C. van de Merbel, Rainer Bischoff Opublikowane w: Analytical Chemistry, Numer 93/40, 2021, Strona(/y) 13597-13605, ISSN 0003-2700 Wydawca: American Chemical Society DOI: 10.1021/acs.analchem.1c02807 Analytical tools for the characterization of deamidation in monoclonal antibodies Autorzy: Baubek Spanov, Natalia Govorukhina, Nico C. van de Merbel, Rainer Bischoff Opublikowane w: Journal of Chromatography Open, 2022, ISSN 2772-3917 Wydawca: Elsevier B.V. DOI: 10.1016/j.jcoa.2021.100025 Comparison of LFQ and IPTL for Protein Identification and Relative Quantification Autorzy: Christina Johannsen, Christian J. Koehler, Bernd Thiede Opublikowane w: Molecules, 2021, ISSN 1420-3049 Wydawca: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules26175330 Book chapters (1) Preparing Proteoforms of Therapeutic Proteins for Top-Down Mass Spectrometry Autorzy: Siti Nurul Hidayah, Manasi Gaikwad, Laura Heikaus, Hartmut Schlüter Opublikowane w: Proteoforms [Working Title], 2020 Wydawca: IntechOpen DOI: 10.5772/intechopen.89644 Wyszukiwanie danych OpenAIRE... Podczas wyszukiwania danych OpenAIRE wystąpił błąd Brak wyników
