ACOUSTIC MARKERS FOR ENHANCED REMOTE SENSING OF RADIATION DOSES

Informacje na temat projektu

AMPHORA

Identyfikator umowy o grant: 766456

DOI

10.3030/766456

Projekt został zamknięty

Data podpisania przez KE 8 Sierpnia 2017

Data rozpoczęcia 1 Listopada 2017

Data zakończenia 30 Kwietnia 2022

Finansowanie w ramach

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Koszt całkowity

€ 3 932 775,00

Wkład UE

€ 3 932 775,00

Koordynowany przez

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Other (3)

Project Closing Event

Project closing event

Targeted UCA batches, with in-vitro evaluation of targeting efficacy

Availability of targeted UCA batches with invitro evaluationof targeting efficacy

Project Opening Event

Project opening event

Open Research Data Pilot (5)

Optimized Targeted Dosimetric UCAs

UCAs that are accumulating in and around tumour tissue

Data Management Plan

final data management plan

Dissemination and Exploitation Plan

Final Dissemination and Exploitation Plan

Updated Dissemination and Exploitation Plan (1st major update)
Updated Dissemination and Exploitation Plan (2nd major update)

Updated Dissemination and Exploitation Plan 2nd and final major update

Documents, reports (5)

review meeting documents meeting 2
review meeting documents meeting 3
Shortlist of Dosimetric UCAs

Report regarding UCA formulations and PCF & acoustic characterization, and in-vitro biological studies. Definition of UCA design priorities, based on dose-sensitivity, robustness of acoustic response w.r.t. measurement conditions and bio-compatibility.

review meeting documents meeting 1
Intermediate report on backscatter modeling

Intermediate report on the backscatter model and its validation

Demonstrators, pilots, prototypes (1)

In Vitro POC: Homogeneous Dilutions

First Ultrasound approach for dose read out. Approach demonstrated in homogeneous UCA dilutions.

Websites, patent fillings, videos etc. (1)

Website & project logo

website and project logo of AMFORA

Publikacje

Conference proceedings (2)

Rectangular 1014 element matrix array for transperineal imaging

Autorzy: D. Speicher, H. Hewener, S. Therre, S. Tretbar and M. Fournelle,
Opublikowane w: IEEE IUS 2021, 2021, Strona(/y) 1-4, ISBN 978-1-6654-0355-9
Wydawca: IEEE
DOI: 10.1109/ius52206.2021.9593385

Development and characterization of a sparse ellipsoidal 256 element array for volumetric ultrasound imaging

Autorzy: M. Fournelle et al.
Opublikowane w: IEEE International Ultrasonics Symposium (IUS), 2021, Strona(/y) 1-3, ISBN 978-1-6654-4777-5
Wydawca: IEEE
DOI: 10.1109/ius52206.2021.9593506

Peer reviewed articles (14)

Real-Time Volumetric Ultrasound Research Platform with 1024 Parallel Transmit and Receive Channels

Autorzy: Christoph Risser; Holger Hewener; Marc Fournelle; Heinrich Fonfara; Selina Barry-Hummel; Steffen Weber; Daniel Speicher; Steffen Tretbar
Opublikowane w: Volume 11, Numer 4, 2021, ISSN 2076-3417
Wydawca: Applied Sciences
DOI: 10.3390/app11135795

Effect of a Radiotherapeutic Megavoltage Beam on Ultrasound Contrast Agents

Autorzy: Collado-Lara, G., Heymans, S.V., Godart, J., D’Agostino, E., D’hooge, J., Van Den Abeele, K., Vos, H.J., de Jong, N.,
Opublikowane w: Ultrasound in Medicine & Biology, Numer 47/7, 2021, Strona(/y) 1857-1867, ISSN 0301-5629
Wydawca: Elsevier BV
DOI: 10.1016/j.ultrasmedbio.2021.02.021

Deep learning for dose assessment in radiotherapy by the super-localization of vaporized nanodroplets in high frame rate ultrasound imaging

Autorzy: Brent van der Heyden, Sophie Heymans, Bram Carlier, Gonzalo Collado-Lara, Edmond Sterpin and Jan D'hooge
Opublikowane w: Physics in Medicine & Biology, Numer 00319155, 2022, Strona(/y) 5015, ISSN 0031-9155
Wydawca: Institute of Physics Publishing
DOI: 10.1088/1361-6560/ac6cc3

Acoustic Modulation Enables Proton Detection with Nanodroplets at Body Temperature

Autorzy: Heymans, S.V., Collado-Lara, G., Rovituso, M., Vos, H.J., D’hooge, J., De Jong, N., Van Den Abeele, K.,
Opublikowane w: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Numer 69/6, 2022, Strona(/y) 2028-2038, ISSN 0885-3010
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2022.3164805

Spatially Variant Ultrasound Attenuation Mapping Using a Regularized Linear Least-Squares Approach

Autorzy: Jasleen Birdi; Jan D'hooge; Alexander Bertrand
Opublikowane w: Crossref, Numer 4, 2022, Strona(/y) 1596 - 1609, ISSN 0885-3010
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2022.3157949

Fast linear least-squares method for ultrasound attenuation and backscatter estimation

Autorzy: Jasleen Birdi; Arun Muraleedharan; Jan D'hooge; Alexander Bertrand
Opublikowane w: Ultrasonics, Numer 1, 2021, ISSN 0041-624X
Wydawca: Elsevier BV
DOI: 10.1016/j.ultras.2021.106503

Modulating ultrasound contrast generation from injectable nanodroplets for proton range verification by varying the degree of superheat.

Autorzy: Sophie V. Heymans; Bram Carlier; Yosra Toumia; Sjoerd Nooijens; Marcus Ingram; Andrea Giammanco; Emiliano D'Agostino; Wouter Crijns; Alexander Bertrand; Gaio Paradossi; Uwe Himmelreich; Jan D'hooge; Edmond Sterpin; Koen Van Den Abeele
Opublikowane w: Medical Physics, (2021), Numer 1, 2021, ISSN 0094-2405
Wydawca: American Association of Physicists in Medicine
DOI: 10.1002/mp.14778

Ultrasound-assisted carbon ion dosimetry and range measurement using injectable polymer-shelled phase-change nanodroplets: in vitro study

Autorzy: Yosra Toumia,corresponding author1,2 Marco Pullia,3 Fabio Domenici,1,2 Angelica Facoetti,3 Michele Ferrarini,3 Sophie V. Heymans,4,5,6 Bram Carlier,7 Koen Van Den Abeele,4 Edmond Sterpin,7 Jan D’hooge,5 Emiliano D’Agostino,8 and Gaio Paradossi1,2
Opublikowane w: Scientific reports, Numer 12(1), 2022, Strona(/y) 8012, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-11524-x

Utility Metrics for Assessment and Subset Selection of Input Variables for Linear Estimation [Tips & Tricks]

Autorzy: Alexander Bertrand
Opublikowane w: IEEE Signal Processing Magazine, Numer 35/6, 2018, Strona(/y) 93-99, ISSN 1053-5888
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/MSP.2018.2856632

Dynamics of the phospholipid shell of microbubbles: a fluorescence photoselection and spectral phasor approach

Autorzy: Eli Slenders, Senne Seneca, Sumit Kumar Pramanik, Nick Smisdom, Peter Adriaensens, Martin vandeVen, Anitha Ethirajan, Marcel Ameloot
Opublikowane w: Chemical Communications, Numer 54/38, 2018, Strona(/y) 4854-4857, ISSN 1359-7345
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c8cc01012a

Proton range verification with ultrasound imaging using injectable radiation sensitive nanodroplets: a feasibility study.

Autorzy: Bram Carlier; Sophie V. Heymans; Sjoerd Nooijens; Yosra Toumia; Marcus Ingram; Gaio Paradossi; Emiliano D'Agostino; Uwe Himmelreich; Jan D'hooge; Koen Van Den Abeele; Edmond Sterpin
Opublikowane w: Physics in Medicine and Biology, Vol. 65, no.6, p. 17 (2020), Numer 6, 2020, ISSN 1361-6560
Wydawca: -
DOI: 10.1088/1361-6560/ab7506

Ultrasound-assisted investigation of photon triggered vaporization of poly(vinylalcohol) phase-change nanodroplets: A preliminary concept study with dosimetry perspective

Autorzy: Yosra Toumia; Roberto Miceli; Fabio Domenici; Sophie V. Heymans; Bram Carlier; Madalina Cociorb; Letizia Oddo; Piero Rossi; Rolando Maria D'Angellilo; Edmond Sterpin; Emiliano D'Agostino; Koen Van Den Abeele; Jan D'hooge; Gaio Paradossi
Opublikowane w: Physica Medica, Vol. 89, p. 232-242 (2021), Numer 3, 2021, ISSN 1120-1797
Wydawca: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.08.006

Spatiotemporal Distribution of Nanodroplet Vaporization in a Proton Beam Using Real-Time Ultrasound Imaging for Range Verification

Autorzy: Gonzalo Collado-Lara; Sophie V. Heymans; Sophie V. Heymans; Marta Rovituso; Bram Carlier; Yosra Toumia; Martin D. Verweij; Martin D. Verweij; Gaio Paradossi; Edmond Sterpin; Hendrik J. Vos; Hendrik J. Vos; Jan D'hooge; Nico de Jong; Nico de Jong; Koen Van Den Abeele; Verya Daeichin
Opublikowane w: VOLUME=48;ISSUE=1;ISSN=0301-5629;TITLE=Ultrasound in Medicine & Biology, Numer 3, 2022, ISSN 0301-5629
Wydawca: Elsevier BV
DOI: 10.1016/j.ultrasmedbio.2021.09.009

Phase Change Ultrasound Contrast Agents with a Photopolymerized Diacetylene Shell

Autorzy: Toumia, Y.; Cerroni, B.; Domenici, F.; Lange, H.; Bianchi, L.; Cociorb, M.; Brasili, F.; Chiessi, E.; D' Agostino, E.; Van Den Abeele, K.; Heymans, S. V.; D' Hooge, J.; Paradossi, G.
Opublikowane w: Langmuir, Numer 5, 2019, ISSN 0743-7463
Wydawca: American Chemical Society
DOI: 10.1021/acs.langmuir.9b01160