Artificial metabolic cells for biomanufacturing of bio-based chiral fine chemicals

Publikacje

Design of the Enzyme-Carrier Interface to Overcome the O2 and NADH Mass Transfer Limitations of an Immobilized Flavin Oxidase.

Autorzy: Ana I. Benítez-Mateos; Ana I. Benítez-Mateos; Christina Huber; Bernd Nidetzky; Juan M. Bolivar; Juan M. Bolivar; Fernando López-Gallego; Fernando López-Gallego
Opublikowane w: ACS Applied Materials and Interfaces, Numer 5, 2020, Strona(/y) 56027-56038, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/acsami.0c17568

Selective Coimmobilization of His-Tagged Enzymes on Yttrium-Stabilized Zirconia-Based Membranes for Continuous Asymmetric Bioreductions

Autorzy: Andrés-Sanz, D; Diamanti, E; Di Silvo, D; Gurauskis, J; López-Gallego, F.
Opublikowane w: ACS Applied Materials and Interfaces, Numer 14-3, 2022, Strona(/y) 4285-4296, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/acsami.1c20738

A heterogeneous chemoenzymatic route toward the continuous transformation of γ-alkynoic acids into γ-hydroxy acids

Autorzy: Javier Santiago-Arcos, Daniel Andrés-Sanz, Nicolás Ríos-Lombardía, Susana Carregal-Romero, Desiré di Silvio, Irantzu Llarena, Joaquín García-Álvarez, Javier González-Sabín, Fernando López-Gallego
Opublikowane w: Cell Reports Physical Science, Numer 5, 2024, Strona(/y) 102015, ISSN 2666-3864
Wydawca: Elsevier
DOI: 10.1016/j.xcrp.2024.102015

Self-sufficient asymmetric reduction of β-ketoesters catalysed by a novel and robust thermophilic alcohol dehydrogenase co-immobilised with NADH

Autorzy: Alejandro H. Orrego, Daniel Andrés-Sanz, Susana Velasco-Lozano, Mercedes Sanchez-Costa, José Berenguer, José M. Guisan, Javier Rocha-Martin, Fernando López-Gallego
Opublikowane w: Catalysis Science & Technology, Numer 11/9, 2021, Strona(/y) 3217-3230, ISSN 2044-4753
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1cy00268f

Intraparticle Kinetics Unveil Crowding and Enzyme Distribution Effects on the Performance of Cofactor-Dependent Heterogeneous Biocatalysts

Autorzy: Eleftheria Diamanti; Javier Santiago-Arcos; Daniel A. Grajales-Hernández; Nicolette Czarnievicz; Natalia Comino; Irantzu Llarena; Desiré Di Silvio; Aitziber L. Cortajarena; Fernando López-Gallego
Opublikowane w: ACS Catalysis, Numer 2, 2021, Strona(/y) 15051-15067, ISSN 2155-5435
Wydawca: American Chemical Society
DOI: 10.1021/acscatal.1c03760

Surpassing Substrate–Enzyme Competition by Compartmentalization

Autorzy: Eleftheria Diamanti, Daniel Andrés-Sanz, Alejandro H. Orrego, Susana Carregal-Romero, Fernando López-Gallego
Opublikowane w: ACS Catalysis, Numer 13, 2023, Strona(/y) 11441-11454, ISSN 2155-5435
Wydawca: American Chemical Society
DOI: 10.1021/acscatal.3c01965

Cell-free biosynthesis of ω-hydroxy acids boosted by a synergistic combination of alcohol dehydrogenases

Autorzy: Susana Velasco; Javier Santiago-Arcos; Maria Grazia; Fernando López-Gallego
Opublikowane w: ChemSusChem, Numer 1, 2022, ISSN 1864-5631
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.26434/chemrxiv-2021-vgprq

Engineered repeat proteins as scaffolds to assemble multi-enzyme systems for efficient cell-free biosynthesis

Autorzy: Alba Ledesma-Fernandez, Susana Velasco-Lozano, Javier Santiago-Arcos, Fernando López-Gallego, Aitziber L. Cortajarena
Opublikowane w: Nature Communications, Numer 14, 2023, Strona(/y) 14 - 1 (2587 ), ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-38304-z

Characterization and evaluation of immobilized enzymes for applications in flow reactors

Autorzy: Juan M. Bolivar, Fernando López-Gallego
Opublikowane w: Current Opinion in Green and Sustainable Chemistry, Numer 25, 2020, Strona(/y) 100349, ISSN 2452-2236
Wydawca: Elsevier
DOI: 10.1016/j.cogsc.2020.04.010

Light-Driven Catalytic Regulation of Enzymes at the Interface with Plasmonic Nanomaterials

Autorzy: Heloise Ribeiro de Barros, Fernando López-Gallego, Luis M. Liz-Marzán
Opublikowane w: Biochemistry, Numer 60/13, 2021, Strona(/y) 991-998, ISSN 0006-2960
Wydawca: American Chemical Society
DOI: 10.1021/acs.biochem.0c00447

Multienzyme Coimmobilization on Triheterofunctional Supports

Autorzy: Javier Santiago-Arcos, Susana Velasco-Lozano, Fernando López-Gallego
Opublikowane w: Biomacromolecules, Numer 24, 2023, Strona(/y) 929-942, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.2c01364

Metal substrate catalysis in the confined space for platinum drug delivery

Autorzy: Susana Velasco-Lozano; Silvia Alonso-de Castro; Carlos Sanchez-Cano; Carlos Sanchez-Cano; Ana I. Benítez-Mateos; Fernando López-Gallego; Luca Salassa; Luca Salassa; Luca Salassa
Opublikowane w: Chemical Science, Numer 4, 2021, Strona(/y) 59-67, ISSN 2041-6520
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1sc05151b

Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters

Autorzy: Nicoll Zeballos, Natalia Comino, Daniel Andrés-Sanz, Javier Santiago-Arcos, Mikel Azkargorta, Felix Elortza, Eleftheria Diamanti, Fernando López-Gallego
Opublikowane w: ACS Applied Materials & Interfaces, Numer 16, 2024, Strona(/y) 833-846, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/acsami.3c15993

ATP‐Independent and Cell‐Free Biosynthesis of β‐Hydroxy Acids Using Vinyl Esters as Smart Substrates

Autorzy: Alejandro H. Orrego, Maria Grazia Rubanu, Idania L. López, Daniel Andrés‐Sanz, Guillermo García‐Marquina, German E. Pieslinger, Luca Salassa, Fernando López‐Gallego
Opublikowane w: Angewandte Chemie International Edition, Numer 62, 2023, Strona(/y) 62 - 13 (e202218312), ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202218312

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