Bridging the gap between Mind, Brain and Body: exosome role and monitoring

Informacje na temat projektu

MindGAP

Identyfikator umowy o grant: 829040

DOI

10.3030/829040

Projekt został zamknięty

Data podpisania przez KE 22 Lutego 2019

Data rozpoczęcia 1 Kwietnia 2019

Data zakończenia 31 Marca 2024

Finansowanie w ramach

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Koszt całkowity

€ 4 435 830,00

Wkład UE

€ 4 435 830,00

Koordynowany przez

UNIVERSIDADE DE COIMBRA
Portugal

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (10)

Outer characterization of EXOs

Outer characterization of EXOs, to find biomarkers to link EXOs to their brain origin.

Website, Logo and Media

Report on the website, logo and eventual media accounts e.g. Facebook, Twitter.

PA assembly on non-conductive substrates

Plastic Antibody assembly on nonconductive substrates

Analytical features with standards

Analytical features with standards.NOTE: analysis should be carried out in the prototype.

PA assembly on conductive substrates

Plastic Antibody assembly on conductive substrates

Specification for sensor and designs planned

Specification for sensor and designs planned.

Computing selected conditions for PA

Computing selected conditions to assembly the plastic antibodies.

Report on Kick-off Meeting

Report on Kick-off meeting

Biomarkers in Brain EXOs (individuals)

Biomarkers in Brain EXOs individuals

Inner characterization of EXOs

Inner characterization of EXOs to examine the cargo of brain-EXOs, as a key element of the transmitted information.

Open Research Data Pilot (1)

Data Management Plan (interim)

Data Management Plan, reporting research data type and size, how it will be stored so that is findable, accessible, interoperable and reusable (FAIR) during and after the project.

Publikacje

Peer reviewed articles (31)

Evidence of psychological and biological effects of structured Mindfulness‐Based Interventions for cancer patients and survivors: A meta‐review

Autorzy: Juliana Pedro, Sara Monteiro‐Reis, Carina Carvalho‐Maia, Rui Henrique, Carmen Jerónimo, Eunice R. Silva
Opublikowane w: Psycho-Oncology, Numer 30/11, 2021, Strona(/y) 1836-1848, ISSN 1057-9249
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/pon.5771

Human Adult Astrocyte Extracellular Vesicle Transcriptomics Study Identifies Specific RNAs Which Are Preferentially Secreted as EV Luminal Cargo

Autorzy: Shanthi, Keerthanaa Balasubramanian, Daniel Fischer, Abhishek Sharma, Antti Kiviniemi, Mika Kaakinen, Seppo J. Vainio, and Geneviève Bart.
Opublikowane w: Genes, Numer 14, 2023, Strona(/y) 853, ISSN 2073-4425
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14040853

Trisk 95 as a novel skin mirror for normal and diabetic systemic glucose level

Autorzy: Nsrein Ali, Hamid Reza Rezvani, Diana Motei, Sufyan Suleman, Walid Mahfouf, Isabelle Marty, Veli-Pekka Ronkainen, Seppo J. Vainio
Opublikowane w: Scientific Reports, Numer 10/1, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-68972-6

Time-gated Raman spectroscopy and proteomics analyses of hypoxic and normoxic renal carcinoma extracellular vesicles.

Autorzy: Anatoliy Samoylenko; Martin Kögler; Artem Zhyvolozhnyi; Olha Makieieva; Genevieve Bart; Sampson Saj Andoh; Matthieu Roussey; Seppo Vainio; Jussi Hiltunen
Opublikowane w: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021), Numer 20452322, 2021, Strona(/y) 1-14, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-99004-6

Identification of extracellular nanoparticle subsets by nuclear magnetic resonance.

Autorzy: Sharif Ullah; Vladimir V. Zhivonitko; Anatoliy Samoylenko; Artem Zhyvolozhnyi; Sirja Viitala; Santeri Kankaanpää; Sanna Komulainen; Leif Schröder; Seppo Vainio; Ville-Veikko Telkki
Opublikowane w: Chemical Science, Numer 20416539, 2021, Strona(/y) 8311-8319, ISSN 2041-6539
Wydawca: RSC
DOI: 10.1039/d1sc01402a

Smart bio-nano interface derived from zein protein as receptors for biotinyl moiety

Autorzy: Subramanian Suriyanarayanan, Sudip Mandal, Kothandaraman Ramanujam, Ian A. Nicholls,
Opublikowane w: Talanta, Numer 256, 2023, Strona(/y) 124298, ISSN 0039-9140
Wydawca: Elsevier BV
DOI: 10.1016/j.talanta.2023.124298

An ultrasensitive paper-based SERS sensor for detection of nucleolin using silver-nanostars, plastic antibodies and natural antibodies

Autorzy: Akmaral Suleimenova, Manuela F. Frasco, M. Goreti F. Sales
Opublikowane w: Talanta, Numer 279, 2024, Strona(/y) 126543, ISSN 0039-9140
Wydawca: Elsevier BV
DOI: 10.1016/j.talanta.2024.126543

Carbon Electrodes with Gold Nanoparticles for the Electrochemical Detection of miRNA 21-5p

Autorzy: Verónica Morgado Serrano, Inês Simões Patrício Silva, Ana Rita Cardoso and Maria Goreti Ferreira Sales
Opublikowane w: Chemosensors, Numer 22279040, 2022, Strona(/y) 189, ISSN 2227-9040
Wydawca: Chemosensors
DOI: 10.3390/chemosensors10050189

The modulatory role of internet-supported mindfulness-based cognitive therapy on extracellular vesicles and psychological distress in people who have had cancer: a protocol for a two-armed randomized controlled study

Autorzy: Diana R. Pereira, Eunice R. Silva, Carina Carvalho-Maia, Sara Monteiro-Reis, Catarina Lourenço, Rita Calisto, Ricardo João Teixeira, Linda E. Carlson, Genevieve Bart, Seppo J. Vainio, M. Goreti F. Sales, Carmen Jerónimo and Rui Henrique 
Opublikowane w: Trials, Numer 17456215, 2022, Strona(/y) 118, ISSN 1745-6215
Wydawca: BioMed Central
DOI: 10.1186/s13063-022-06045-x

Bacterial nanocellulose membrane as novel substrate for biomimetic structural color materials: Application to lysozyme sensing

Autorzy: Akmaral Suleimenova, Manuela F. Frasco, Francisco A.G. Soares da Silva, Miguel Gama, Elvira Fortunato, M. Goreti F. Sales
Opublikowane w: Biosensors and Bioelectronics: X, Numer 13, 2024, Strona(/y) 100310, ISSN 2590-1370
Wydawca: Elsevier
DOI: 10.1016/j.biosx.2023.100310

Au nanostar nanoparticle as a bio-imaging agent and its detection and visualization in biosystems

Autorzy: Perevedentseva, E.; Ali, N.; Lin, Y.-C.; Karmenyan, A.; Chang, C.-C.; Bibikova, O.; Skovorodkin, I.; Prunskaite-Hyyryläinen, R.; Vainio, S. J.; Kinnunen, M.; Cheng, C.-L.
Opublikowane w: Biomedical Optics Express, Numer 10, 2020, Strona(/y) 5872-5885, ISSN 2156-7085
Wydawca: The Optical Society
DOI: 10.1364/boe.401462

Amplified Sensitivity in SERS Detection of L1CAM With Silver Plasmonic Mesoporous Silica Capsules on an Imprinted Films

Autorzy: Yuselis Castaño‐Guerrero, Belén Arjones‐Fernández, Felismina T.C. Moreira, Ramon A. Alvarez‐Puebla, Miguel A. Correa‐Duarte, H. Águas, M. Goreti F. Sales
Opublikowane w: Advanced Materials Interfaces, 2024, ISSN 2196-7350
Wydawca: Wiley
DOI: 10.1002/admi.202400299

Fabrication and sensing properties of a molecularly imprinted polymer on a photonic PDMS substrate for the optical detection of C-reactive protein

Autorzy: Sara Resende, José Fernandes, Patrícia C. Sousa, Carlos Calaza, Manuela F. Frasco, Paulo P. Freitas, M. Goreti F. Sales
Opublikowane w: Chemical Engineering Journal, Numer 485, 2024, Strona(/y) 149924, ISSN 1385-8947
Wydawca: Elsevier BV
DOI: 10.1016/j.cej.2024.149924

Molecular Imprinting on Nanozymes for Sensing Applications

Autorzy: Ana R. Cardoso; Manuela F. Frasco; Manuela F. Frasco; Manuela F. Frasco; Verónica M. Serrano; Verónica M. Serrano; Verónica M. Serrano; Elvira Fortunato; Maria Goreti Ferreira Sales; Maria Goreti Ferreira Sales; Maria Goreti Ferreira Sales
Opublikowane w: Biosensors, Vol 11, Iss 152, p 152 (2021), Numer 20796374, 2021, Strona(/y) 152, ISSN 2079-6374
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios11050152

Sustainable synthesis of hierarchically grown chloramphenicol-imprinted poly(caffeic acid) nanostructured films

Autorzy: Subramanian Suriyanarayanan, Ganapathi Rao Kandregula, Kothandaraman Ramanujam, Ian A. Nicholls
Opublikowane w: Journal of Applied Polymer Synthesis, Numer 140, 2023, Strona(/y) e53560, ISSN 0021-8995
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/app.53560

Towards Peptide and Protein Recognition by Antibody Mimicking Synthetic Polymers – Background, State of the Art, and Future Outlook

Autorzy: Ian A. Nicholls, Jesper G. Wiklander
Opublikowane w: Australian Journal of Chemistry, Numer 73/4, 2020, Strona(/y) 300, ISSN 0004-9425
Wydawca: Commonwealth Scientific and Industrial Research Organization Publishing
DOI: 10.1071/ch20020

Recent advances in virus imprinted polymers

Autorzy: Mariana S. Amorim, M. Goreti F. Sales and Manuela F. Frasco
Opublikowane w: Biosensors and Bioelectronics: X, Numer 25901370, 2022, Strona(/y) 100131, ISSN 2590-1370
Wydawca: Elsevier
DOI: 10.1016/j.biosx.2022.100131

Secreted Extracellular Vesicle Molecular Cargo as a Novel Liquid Biopsy Diagnostics of Central Nervous System Diseases

Autorzy: Sara Monteiro-Reis, Carina Carvalho-Maia, Genevieve Bart, Seppo J. Vainio, Juliana Pedro, Eunice R. Silva, Goreti Sales, Rui Henrique, Carmen Jerónimo
Opublikowane w: International Journal of Molecular Sciences, Numer 22/6, 2021, Strona(/y) 3267, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22063267

Improved Solvothermal Synthesis of γ-Fe2O3 Magnetic Nanoparticles for SiO2 Coating

Autorzy: Rashmi Mahajan, Subramanian Suriyanarayanan, Ian A. Nicholls
Opublikowane w: Nanomaterials, Numer 11/8, 2021, Strona(/y) 1889, ISSN 2079-4991
Wydawca: mdpi
DOI: 10.3390/nano11081889

Photonics in nature and bioinspired designs: sustainable approaches for a colourful world

Autorzy: Raquel Vaz, Manuela F. Frasco, M. Goreti F. Sales
Opublikowane w: Nanoscale Advances, 2020, ISSN 2516-0230
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d0na00445f

Molecular Dynamics in the Study and Development of Molecularly Imprinted Materials – Status Quo, Quo Vadis?

Autorzy: Ian A. Nicholls; Kerstin Golker; Jesper G. Wiklander
Opublikowane w: Preprints.org, Numer 2022020154, 2022, Strona(/y) 2022020154, ISSN 2310-287X
Wydawca: Preprints
DOI: 10.20944/preprints202202.0154.v1

Portable and Autonomous PEDOT-Modified Flexible Paper-Based Methanol Fuel Cell Sensing Platform Applied to L1CAM Recombinant Protein Detection

Autorzy: Liliana P. T. Carneiro, Alexandra M. F. R. Pinto, Dzmitry Ivanou, Adélio M. Mendes, and M. Goreti F. Sales
Opublikowane w: ACS applied polymer materials, 2023, Strona(/y) 3207–3221, ISSN 2637-6105
Wydawca: ACS
DOI: 10.1021/acsapm.3c02781

Development of an electrochemical biosensor for galectin-3 detection in point-of-care.

Autorzy: Sofia M.V. Cerqueira, Rúben Fernandes, Felismina T.C. Moreira, M. Goreti F. Sales
Opublikowane w: Micrhochemical journal, Numer 164, 2021, Strona(/y) 105992, ISSN 1095-9149
Wydawca: Elsevier
DOI: 10.1016/j.microc.2021.105992

Porosity of Molecularly Imprinted Polymers Investigated by ¹²⁹Xe NMR Spectroscopy

Autorzy: Matteo Boventi; Michele Mauri; Kerstin Golker; Jesper G. Wiklander; Ian A. Nicholls; Roberto Simonutti
Opublikowane w: ACS Applied Polymer Materials, Numer 4, 2022, Strona(/y) 8740-8749, ISSN 2637-6105
Wydawca: ACS
DOI: 10.1021/acsapm.2c01084

Paper-based (bio)sensor for label-free detection of 3-nitrotyrosine in human urine samples using molecular imprinted polymer

Autorzy: Gabriela V. Martins, Ana C. Marques, Elvira Fortunato, M. Goreti F. Sales
Opublikowane w: Sensing and Bio-Sensing Research, Numer 28, 2020, Strona(/y) 100333, ISSN 2214-1804
Wydawca: Elsevier BV
DOI: 10.1016/j.sbsr.2020.100333

Breaking the classics: Next-generation biosensors for the isolation, profiling and detection of extracellular vesicles

Autorzy: Raquel Vaz, Verónica M Serrano, Yuselis Castaño-Guerrero, Ana R. Cardoso, Manuela Frasco, M. Goreti F. Sales
Opublikowane w: Biosensors and Bioelectronics: X, Numer 25901370, 2022, Strona(/y) 100115, ISSN 2590-1370
Wydawca: Elsevier
DOI: 10.1016/j.biosx.2022.100115

Urinary volatilomics unveils a candidate biomarker panel for noninvasive detection of clear cell renal cell carcinoma.

Autorzy: Joana Pinto, Filipa Amaro, Ana Rita Lima, Carina Carvalho-Maia, Carmen Jerónimo, Rui Henrique, Maria de Lourdes Bastos, Márcia Carvalho, and Paula Guedes de Pinho
Opublikowane w: Journal of Proteome research, Numer 20, 2021, Strona(/y) 3068–3077, ISSN 1535-3893
Wydawca: American Chemical Society
DOI: 10.1021/acs.jproteome.0c00936

MicroRNAs in Extracellular Vesicles in Sweat Change in Response to Endurance Exercise

Autorzy: Sira Karvinen, Tero Sievänen, Jari E. Karppinen, Pekka Hautasaari, Geneviève Bart, Anatoliy Samoylenko, Seppo J. Vainio, Juha P. Ahtiainen, Eija K. Laakkonen, Urho M. Kujala
Opublikowane w: Frontiers in Physiology, Numer 11, 2020, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.00676

Oxytocin-Selective Nanogel Antibody Mimics

Autorzy: Rashmi Mahajan, Subramanian Suriyanarayanan, Gustaf D. Olsson, Jesper G. Wiklander, Teodor Aastrup, Börje Sellergren and Ian A. Nicholls
Opublikowane w: International Journal of Molecular Sciences, Numer 14220067, 2022, Strona(/y) 2534, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23052534

Green photonic biosensing: Approaching sustainability in point-of-care diagnostics

Autorzy: Raquel Vaz, M. Goreti F. Sales, Manuela F. Frasco
Opublikowane w: TrAC, Trends in Analytical Chemistry, Numer 177, 2024, Strona(/y) 117771, ISSN 0165-9936
Wydawca: Elsevier BV
DOI: 10.1016/j.trac.2024.117771

Detection of serum calprotectin based on molecularly imprinted photonic hydrogels: A novel approach for IBD diagnosis

Autorzy: Sara Resende, Manuela F. Frasco, Paulo P. Freitas, M. Goreti F. Sales
Opublikowane w: Biosensors and Bioelectronics: X, Numer 13, 2023, Strona(/y) 100313, ISSN 2590-1370
Wydawca: Elsevier
DOI: 10.1016/j.biosx.2023.100313

Conference proceedings (2)

Bioinspired photonic polymeric sensors for analysing exosomes

Autorzy: Vaz, Raquel; Frasco, Manuela; Sales, M. G. F.
Opublikowane w: Encontro Ciência'21. Lisboa, Jun 28-30, 2021., 2020
Wydawca: FCT

Bioinspired photonic polymeric sensors for analysing exosomes

Autorzy: Vaz, Raquel; Frasco, Manuela; Sales, M. G. F.
Opublikowane w: Encontro Ciência'21. Lisboa, Jun 28-30, 2021., Numer 7, 2021
Wydawca: FCT

Book chapters (3)

Using Molecular in the Study of Molecularly Imprinted

Autorzy: Gustaf D. Olsson, Jesper G. Wiklander, Ian A. Nicholls
Opublikowane w: Molecularly Imprinted Polymers - Methods and Protocols, Numer 2359, 2021, Strona(/y) 241-268, ISBN 978-1-0716-1628-4
Wydawca: Springer US
DOI: 10.1007/978-1-0716-1629-1_21

Biomimetic strategies for biosensing

Autorzy: Ana R. Cardoso, Liliana P.T. Carneiro, Akmaral Suleimenova, Manuela F. Frasco, M. Goreti F. Sales
Opublikowane w: Nature-Derived Sensors, 2025, Strona(/y) 223-265
Wydawca: Elsevier
DOI: 10.1016/b978-0-443-22002-9.00003-8

Biosensors: concept and importance in point-of-care disease diagnosis

Autorzy: Raquel Vaz, Manuela F. Frasco and M. Goreti F. Sales
Opublikowane w: Biosensor Based Advanced Cancer Diagnostics, From Lab to Clinics, 2021, Strona(/y) 59-84, ISBN 978-0-12-823424-2
Wydawca: Academic Press
DOI: 10.1016/b978-0-12-823424-2.00001-6

Non-peer reviewed articles (1)

The Use of Computational Methods for the Development of Molecularly Imprinted Polymers

Autorzy: Ian A. Nicholls, Kerstin Golker, Gustaf D. Olsson, Subramanian Suriyanarayanan, Jesper G. Wiklander
Opublikowane w: Polymers, Numer 13/17, 2021, Strona(/y) 2841, ISSN 2073-4360
Wydawca: mdpi
DOI: 10.3390/polym13172841