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A Single-Molecule Technology for Resolving Chaperone Action in Neurodegenerative Diseases

Publikacje

Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution

Autorzy: William E. Arter, Catherine K. Xu, Marta Castellana-Cruz, Therese W. Herling, Georg Krainer, Kadi L. Saar, Janet R. Kumita, Christopher M. Dobson, Tuomas P. J. Knowles
Opublikowane w: Nano Letters, Issue 20/11, 2020, Page(s) 8163-8169, ISSN 1530-6984
Wydawca: American Chemical Society
DOI: 10.1021/acs.nanolett.0c03260

Microfluidic approaches for the analysis of protein–protein interactions in solution

Autorzy: William E. Arter, Aviad Levin, Georg Krainer, Tuomas P. J. Knowles
Opublikowane w: Biophysical Reviews, Issue 12/2, 2020, Page(s) 575-585, ISSN 1867-2450
Wydawca: Springer Verlag
DOI: 10.1007/s12551-020-00679-4

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions

Autorzy: Georg Krainer, Timothy J. Welsh, Jerelle A. Joseph, Jorge R. Espinosa, Sina Wittmann, Ella de Csilléry, Akshay Sridhar, Zenon Toprakcioglu, Giedre Gudiškytė, Magdalena A. Czekalska, William E. Arter, Jordina Guillén-Boixet, Titus M. Franzmann, Seema Qamar, Peter St George-Hyslop, Anthony A. Hyman, Rosana Collepardo-Guevara, Simon Alberti, Tuomas P. J. Knowles
Opublikowane w: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-21181-9

Single particle zeta-potential measurements reveal the role of electrostatics in protein condensate stability

Autorzy: Welsh, Timothy J.; Krainer, Georg; Espinosa, Jorge R.; Joseph, Jerelle A.; Sridhar, Akshay; Jahnel, Marcus; Arter, William E.; Saar, Kadi L.; Alberti, Simon; Collepardo-Guevara, Rosana; Knowles, Tuomas P.J.
Opublikowane w: Biorxiv, 2020
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.04.20.047910

The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril Ends

Autorzy: Matthias M. Schneider, Saurabh Gautam, Therese W. Herling, Ewa Andrzejewska, Georg Krainer, Alyssa M. Miller, Quentin A. E. Peter, Francesco Simone Ruggeri, Michele Vendruscolo, Andreas Bracher, Christopher M. Dobson, F. Ulrich Hartl, Tuomas P. J. Knowles
Opublikowane w: Biorxiv, 2020
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.11.02.365825

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