EMBL Interdisciplinary Postdoc Programme 4

Informacje na temat projektu

EIPOD4

Identyfikator umowy o grant: 847543

DOI

10.3030/847543

Projekt został zamknięty

Data podpisania przez KE 7 Maja 2019

Data rozpoczęcia 1 Grudnia 2019

Data zakończenia 31 Maja 2025

Finansowanie w ramach

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Koszt całkowity

€ 13 240 800,00

Wkład UE

€ 6 620 400,00

Koordynowany przez

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (35)

Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3

Autorzy: Julia Kornienko, Marta Rodríguez-Martínez, Kai Fenzl, Florian Hinze, Daniel Schraivogel, Markus Grosch, Brigit Tunaj, Dominik Lindenhofer, Laura Schraft, Moritz Kueblbeck, Eric Smith, Chad Mao, Emily Brown, Anjali Owens, Ardan M. Saguner, Benjamin Meder, Victoria Parikh, Michael Gotthardt, Lars M. Steinmetz
Opublikowane w: Nature Communications, Numer 14, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-39965-6

Chromatin enables precise and scalable gene regulation with factors of limited specificity

Autorzy: Mindy Liu Perkins, Justin Crocker, Gašper Tkačik
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 122, 2024, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2411887121

MosaiCatcher v2: a single-cell structural variations detection and analysis reference framework based on Strand-seq

Autorzy: Thomas Weber, Marco Raffaele Cosenza, Jan Korbel
Opublikowane w: Bioinformatics, Numer 39, 2023, ISSN 1367-4811
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/bioinformatics/btad633

Variable microtubule architecture in the malaria parasite

Autorzy: Josie L. Ferreira, Vojtěch Pražák, Daven Vasishtan, Marc Siggel, Franziska Hentzschel, Annika M. Binder, Emma Pietsch, Jan Kosinski, Friedrich Frischknecht, Tim W. Gilberger, Kay Grünewald
Opublikowane w: Nature Communications, Numer 14, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-36627-5

A ubiquitin-specific, proximity-based labeling approach for the identification of ubiquitin ligase substrates

Autorzy: Urbi Mukhopadhyay, Sophie Levantovsky, Teresa Maria Carusone, Sarah Gharbi, Frank Stein, Christian Behrends, Sagar Bhogaraju
Opublikowane w: Science Advances, Numer 10, 2024, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.adp3000

Decipher enzymes from human microbiota for drug discovery and development

Autorzy: Mariia A. Beliaeva, Matthias Wilmanns, Michael Zimmermann
Opublikowane w: Current Opinion in Structural Biology, Numer 80, 2024, Strona(/y) 102567, ISSN 0959-440X
Wydawca: Elsevier BV
DOI: 10.1016/j.sbi.2023.102567

Understanding the interplay of membrane trafficking, cell surface mechanics, and stem cell differentiation

Autorzy: Jia Hui Li, Vikas Trivedi, Alba Diz-Muñoz
Opublikowane w: Seminars in Cell & Developmental Biology, Numer 133, 2024, Strona(/y) 123-134, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2022.05.010

A synthetic synthesis to explore animal evolution and development

Autorzy: Mindy Liu Perkins, Lautaro Gandara, Justin Crocker
Opublikowane w: Philosophical Transactions of the Royal Society B: Biological Sciences, Numer 377, 2023, ISSN 0962-8436
Wydawca: Royal Society of London
DOI: 10.1098/rstb.2020.0517

Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles

Autorzy: Ewa Sitarska, Silvia Dias Almeida, Marianne Sandvold Beckwith, Julian Stopp, Jakub Czuchnowski, Marc Siggel, Rita Roessner, Aline Tschanz, Christer Ejsing, Yannick Schwab, Jan Kosinski, Michael Sixt, Anna Kreshuk, Anna Erzberger, Alba Diz-Muñoz
Opublikowane w: Nature Communications, Numer 14, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-41173-1

A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion

Autorzy: E. Podoliak, G. H. U. Lamm, A. Alekseev, E. Marin, A. V. Schellbach, D. A. Fedotov, A. Stetsenko, N. Maliar, G. Bourenkov, T. Balandin, C. Baeken, R. Astashkin, T. R. Schneider, A. Bateman, J. Wachtveitl, I. Schapiro, V. Busskamp, A. Guskov, V. Gordeliy, K. Kovalev
Opublikowane w: Nature Communications, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1101/2023.10.11.561842

Randomly barcoded transposon mutant libraries for gut commensals II: Applying libraries for functional genetics

Autorzy: Carlos Geert Pieter Voogdt, Surya Tripathi, Stefan Oliver Bassler, Saria A. McKeithen-Mead, Emma R. Guiberson, Alexandra Koumoutsi, Afonso Martins Bravo, Cullen Buie, Michael Zimmermann, Justin L. Sonnenburg, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang
Opublikowane w: Cell Reports, Numer 43, 2024, Strona(/y) 113519, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2023.113519

High-precision targeting workflow for volume electron microscopy

Autorzy: Paolo Ronchi ORCID logo , Giulia Mizzon ORCID logo , Pedro Machado ORCID logo , Edoardo D’Imprima ORCID logo , Benedikt T. Best, Lucia Cassella ORCID logo , Sebastian Schnorrenberg, Marta G. Montero ORCID logo , Martin Jechlinger ORCID logo , Anne Ephrussi ORCID logo , Maria Leptin ORCID logo , Julia Mahamid ORCID logo , Yannick Schwab
Opublikowane w: Journal of Cell Biology, Numer June 23, 2021 220(9), 2021, Strona(/y) e202104069, ISSN 1540-8140
Wydawca: Rockefeller University Press
DOI: 10.1083/jcb.202104069

Rapid response of fly populations to gene dosage across development and generations

Autorzy: Xueying C. Li, Lautaro Gandara, Måns Ekelöf, Kerstin Richter, Theodore Alexandrov, Justin Crocker
Opublikowane w: Nature Communications, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1101/2022.09.28.509860

Flow in fetoplacental-like microvessels in vitro enhances perfusion, barrier function, and matrix stability

Autorzy: Marta Cherubini, Scott Erickson, Prasanna Padmanaban, Per Haberkant, Frank Stein, Violeta Beltran-Sastre, Kristina Haase
Opublikowane w: Science Advances, Numer 9, 2024, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.adj8540

Modular control of vertebrate axis segmentation in time and space

Autorzy: Ali Seleit, Ian Brettell, Tomas Fitzgerald, Carina Vibe, Felix Loosli, Joachim Wittbrodt, Kiyoshi Naruse, Ewan Birney, Alexander Aulehla
Opublikowane w: The EMBO Journal, Numer 43, 2024, Strona(/y) 4068-4091, ISSN 1460-2075
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s44318-024-00186-2

Systemic coordination of whole-body tissue remodeling during local regeneration in sea anemones

Autorzy: Stephanie Cheung, Danila Bredikhin, Tobias Gerber, Petrus J. Steenbergen, Soham Basu, Richard Bailleul, Pauline Hansen, Alexandre Paix, Matthew A. Benton, Hendrik C. Korswagen, Detlev Arendt, Oliver Stegle, Aissam Ikmi
Opublikowane w: Developmental Cell, Numer 60, 2025, Strona(/y) 780-793.e7, ISSN 1534-5807
Wydawca: Cell Press
DOI: 10.1016/j.devcel.2024.11.001

Enhancer architecture and chromatin accessibility constrain phenotypic space during Drosophila development

Autorzy: Rafael Galupa, Gilberto Alvarez-Canales, Noa Ottilie Borst, Timothy Fuqua, Lautaro Gandara, Natalia Misunou, Kerstin Richter, Mariana R.P. Alves, Esther Karumbi, Melinda Liu Perkins, Tin Kocijan, Christine A. Rushlow, Justin Crocker
Opublikowane w: Developmental Cell, Numer 58, 2024, Strona(/y) 51-62.e4, ISSN 1534-5807
Wydawca: Cell Press
DOI: 10.1016/j.devcel.2022.12.003

Structural basis of the Integrator complex assembly and association with transcription factors

Autorzy: Michal Razew, Angelique Fraudeau, Moritz M. Pfleiderer, Romain Linares, Wojciech P. Galej
Opublikowane w: Molecular Cell, Numer 84, 2024, Strona(/y) 2542-2552.e5, ISSN 1097-2765
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2024.05.009

Light and electron microscopy continuum-resolution imaging of 3D cell cultures

Autorzy: Edoardo D’Imprima, Marta Garcia Montero, Sylwia Gawrzak, Paolo Ronchi, Ievgeniia Zagoriy, Yannick Schwab, Martin Jechlinger, Julia Mahamid
Opublikowane w: Developmental Cell, 2024, ISSN 1534-5807
Wydawca: Cell Press
DOI: 10.1101/2021.07.02.450855

Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness

Autorzy: Lautaro Gandara, Albert Tsai, Måns Ekelöf, Rafael Galupa, Ella Preger-Ben Noon, Theodore Alexandrov, Justin Crocker
Opublikowane w: Cell Reports, Numer 41, 2024, Strona(/y) 111832, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2022.111832

The molecular dissection of TRIM25’s RNA-binding mechanism provides key insights into its antiviral activity

Autorzy: Lucía Álvarez, Kevin Haubrich, Louisa Iselin, Laurent Gillioz, Vincenzo Ruscica, Karine Lapouge, Sandra Augsten, Ina Huppertz, Nila Roy Choudhury, Bernd Simon, Pawel Masiewicz, Mathilde Lethier, Stephen Cusack, Katrin Rittinger, Frank Gabel, Alexander Leitner, Gracjan Michlewski, Matthias W. Hentze, Frédéric H. T. Allain, Alfredo Castello, Janosch Hennig
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-52918-x

USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder

Autorzy: Julian Cheron, Leonardo Beccari, Perrine Hagué, Romain Icick, Chloé Despontin, Teresa Carusone, Matthieu Defrance, Sagar Bhogaraju, Elena Martin-Garcia, Roberto Capellan, Rafael Maldonado, Florence Vorspan, Jérôme Bonnefont, Alban de Kerchove d’Exaerde
Opublikowane w: Nature Communications, Numer 14, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-44120-2

Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach

Autorzy: Ali Seleit, Alexander Aulehla, Alexandre Paix
Opublikowane w: eLife, Numer 10, 2023, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.75050

Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition

Autorzy: Vadim Kotov, Maxime Killer, Katharina E.J. Jungnickel, Jian Lei, Giada Finocchio, Josi Steinke, Kim Bartels, Jan Strauss, Florine Dupeux, Anne-Sophie Humm, Irina Cornaciu, José A. Márquez, Els Pardon, Jan Steyaert, Christian Löw
Opublikowane w: Cell Reports, Numer 42, 2025, Strona(/y) 112831, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2023.112831

Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction

Autorzy: Surya Tripathi, Carlos Geert Pieter Voogdt, Stefan Oliver Bassler, Mary Anderson, Po-Hsun Huang, Nazgul Sakenova, Tümay Capraz, Sunit Jain, Alexandra Koumoutsi, Afonso Martins Bravo, Valentine Trotter, Michael Zimmerman, Justin L. Sonnenburg, Cullen Buie, Athanasios Typas, Adam M. Deutschbauer, Anthony L. Shiver, Kerwyn Casey Huang
Opublikowane w: Cell Reports, Numer 43, 2024, Strona(/y) 113517, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2023.113517

Ribosomes hibernate on mitochondria during cellular stress

Autorzy: Olivier Gemin, Maciej Gluc, Higor Rosa, Michael Purdy, Moritz Niemann, Yelena Peskova, Simone Mattei, Ahmad Jomaa
Opublikowane w: Nature Communications, Numer 15, 2024, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-024-52911-4

Pulsed stimulated Brillouin microscopy enables high-sensitivity mechanical imaging of live and fragile biological specimens

Autorzy: Fan Yang, Carlo Bevilacqua, Sebastian Hambura, Ana Neves, Anusha Gopalan, Koki Watanabe, Matt Govendir, Maria Bernabeu, Jan Ellenberg, Alba Diz-Muñoz, Simone Köhler, Georgia Rapti, Martin Jechlinger, Robert Prevedel
Opublikowane w: Nature Methods, Numer 20, 2024, Strona(/y) 1971-1979, ISSN 1548-7091
Wydawca: Nature Publishing Group
DOI: 10.1038/s41592-023-02054-z

Induction of territorial behavior and dominance hierarchies in laboratory mice

Autorzy: Dorian Battivelli, Lucas Boldrini, Mohit Jaiswal, Pradnya Patil, Sofia Torchia, Elizabeth Engelen, Luca Spagnoletti, Sarah Kaspar, Cornelius T. Gross
Opublikowane w: Scientific Reports, 2024, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.21203/rs.3.rs-4617383/v1

ColabSeg: An interactive tool for editing, processing, and visualizing membrane segmentations from cryo-ET data

Autorzy: Marc Siggel, Rasmus K. Jensen, Valentin J. Maurer, Julia Mahamid, Jan Kosinski
Opublikowane w: Journal of Structural Biology, Numer 216, 2024, Strona(/y) 108067, ISSN 1047-8477
Wydawca: Academic Press
DOI: 10.1016/j.jsb.2024.108067

Single-cell ultra-high-throughput multiplexed chromatin and RNA profiling reveals gene regulatory dynamics

Autorzy: Sara Lobato-Moreno, Umut Yildiz, Annique Claringbould, Nila H. Servaas, Evi P. Vlachou, Christian Arnold, Hanke Gwendolyn Bauersachs, Víctor Campos-Fornés, Minyoung Kim, Ivan Berest, Karin D. Prummel, Kyung-Min Noh, Mikael Marttinen, Judith B. Zaugg
Opublikowane w: Nature Methods, Numer 22, 2025, Strona(/y) 1213-1225, ISSN 1548-7091
Wydawca: Nature Publishing Group
DOI: 10.1038/s41592-025-02700-8

AlphaDesign: a de novo protein design framework based on AlphaFold

Autorzy: Michael A Jendrusch, Alessio L J Yang, Elisabetta Cacace, Jacob Bobonis, Carlos G P Voogdt, Sarah Kaspar, Kristian Schweimer, Cecilia Perez-Borrajero, Karine Lapouge, Jacob Scheurich, Kim Remans, Janosch Hennig, Athanasios Typas, Jan O Korbel, S Kashif Sadiq
Opublikowane w: Molecular Systems Biology, 2025, ISSN 1744-4292
Wydawca: Nature Publishing Group
DOI: 10.1038/s44320-025-00119-z

Glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling

Autorzy: Kristina S. Stapornwongkul, Elisa Hahn, Patryk Poliński, Laura Salamó Palau, Krisztina Arató, LiAng Yao, Kate Williamson, Nicola Gritti, Kerim Anlas, Mireia Osuna Lopez, Kiran R. Patil, Idse Heemskerk, Miki Ebisuya, Vikas Trivedi
Opublikowane w: Cell Stem Cell, Numer 32, 2025, Strona(/y) 744-758.e7, ISSN 1934-5909
Wydawca: Cell Press
DOI: 10.1016/j.stem.2025.03.011

Mechanisms of inward transmembrane proton translocation

Autorzy: Kirill Kovalev, Fedor Tsybrov, Alexey Alekseev, Vitaly Shevchenko, Dmytro Soloviov, Sergey Siletsky, Gleb Bourenkov, Michael Agthe, Marina Nikolova, David von Stetten, Roman Astashkin, Sergey Bukhdruker, Igor Chizhov, Antoine Royant, Alexander Kuzmin, Ivan Gushchin, Riccardo Rosselli, Francisco Rodriguez-Valera, Nikolay Ilyinskiy, Andrey Rogachev, Valentin Borshchevskiy, Thomas R. Schneider, Ernst
Opublikowane w: Nature Structural & Molecular Biology, Numer 30, 2023, Strona(/y) 970-979, ISSN 1545-9993
Wydawca: Nature Publishing Group
DOI: 10.1038/s41594-023-01020-9

Direct observation of motor protein stepping in living cells using MINFLUX

Autorzy: Takahiro Deguchi, Malina K. Iwanski, Eva-Maria Schentarra, Christopher Heidebrecht, Lisa Schmidt, Jennifer Heck, Tobias Weihs, Sebastian Schnorrenberg, Philipp Hoess, Sheng Liu, Veronika Chevyreva, Kyung-Min Noh, Lukas C. Kapitein, Jonas Ries
Opublikowane w: Science, Numer 379, 2024, Strona(/y) 1010-1015, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.ade2676

A combinatorial approach to uncover an additional Integrator subunit

Autorzy: Sarah R. Offley, Moritz M. Pfleiderer, Avery Zucco, Angelique Fraudeau, Sarah A. Welsh, Michal Razew, Wojciech P. Galej, Alessandro Gardini
Opublikowane w: Cell Reports, Numer 42, 2024, Strona(/y) 112244, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2023.112244

Non-peer reviewed articles (1)

Zooming into lipid droplet biology through the lens of electron microscopy

Autorzy: Wioleta Dudka, Veijo T. Salo, Julia Mahamid
Opublikowane w: FEBS Letters, Numer 598, 2025, Strona(/y) 1127-1142, ISSN 0014-5793
Wydawca: Elsevier BV
DOI: 10.1002/1873-3468.14899