Understanding the impact of nanoplastics on the development of neurological disorders

Informacje na temat projektu

NanoGlia

Identyfikator umowy o grant: 851257

DOI

10.3030/851257

Projekt został zamknięty

Data podpisania przez KE 23 Stycznia 2020

Data rozpoczęcia 1 Kwietnia 2020

Data zakończenia 31 Marca 2026

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 497 193,00

Wkład UE

€ 1 497 193,00

Koordynowany przez

RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Open Research Data Pilot (1)

Data Management Plan

Publikacje

Peer reviewed articles (17)

BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue

Autorzy: Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro, Seniz Yüksel, Ronja Kardinal, Lisa Maria Steinheuer, Fabian Frechen, Luis Henrique Corrêa, Geza Schermann, Christina Klausen, Nelli Blank-Stein, Jonas Schulte-Schrepping, Collins Osei-Sarpong, Matthias Becker, Lorenzo Bonaguro, Marc Beyer, Helen Louise May-Simera, Jelena Zurkovic, Christoph Thiele, Kevin Thurley, Lydia Sorokin,
Opublikowane w: The EMBO Journal, Numer 44, 2026, Strona(/y) 5315-5336, ISSN 1460-2075
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s44318-025-00524-y

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Autorzy: Nikola Makdissi, Maria Francesca Viola, Lisa Maria Steinheuer, Nelli Blank-Stein, Ronja Kardinal, Fabrizio Musacchio, Eliana Franco Taveras, Virginia Aliprandi, Katharina Sieckmann, Akram Abdulkadyrov, Marina L. Mayer, Marie-Louise Diefenbach-Wilke, Diana Fink, Hannes Beckert, Stefan Böhmdorfer, Quentin Deveuve, Frederike J. Graelmann, Katharina Mauel, Nele Kronau, Jake Thomas, David Bejarano, An
Opublikowane w: Nature Metabolism, 2026, ISSN 2522-5812
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s42255-026-01615-8

Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner

Autorzy: Seyhmus Bayar, Lea Seep, Karolína Doubková, Jelena Zurkovic, Margret H. Bülow, Katrin Kierdorf, Reinhard Bauer, Christoph Thiele, Gaia Tavosanis, Jan Hasenauer, Elvira Mass
Opublikowane w: Cells & Development, Numer 183, 2026, Strona(/y) 204040, ISSN 2667-2901
Wydawca: Elsevier BV
DOI: 10.1016/j.cdev.2025.204040

Emerging principles of primary cilia dynamics in controlling tissue organization and function

Autorzy: Jay Gopalakrishnan, Kerstin Feistel, Benjamin M Friedrich, Anne Grapin‐Botton, Nathalie Jurisch‐Yaksi, Elvira Mass, David U Mick, Roman‐Ulrich Müller, Helen May‐Simera, Bernhard Schermer, Miriam Schmidts, Peter Walentek, Dagmar Wachten
Opublikowane w: The EMBO Journal, Numer 42, 2026, ISSN 0261-4189
Wydawca: Nature Publishing Group
DOI: 10.15252/embj.2023113891

Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation

Autorzy: Julia P. Gerber, Jenny Russ, Vijay Chandrasekar, Nina Offermann, Hang-Mao Lee, Sarah Spear, Nicola Guzzi, Simona Maida, Sundararaghavan Pattabiraman, Ruoyu Zhang, Amir H. Kayvanjoo, Preeta Datta, Jagath Kasturiarachchi, Teresa Sposito, Natalia Izotova, Kristian Händler, Peter D. Adams, Teresa Marafioti, Tariq Enver, Jörg Wenzel, Marc Beyer, Elvira Mass, Cristian Bellodi, Joachim L. Schultze, Mel
Opublikowane w: Nature Cell Biology, Numer 23, 2023, Strona(/y) 1224-1239, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-021-00774-y

CD163+ red pulp macrophages interact with marginal metallophilic macrophages during blood-stage malaria to maintain splenic architecture

Autorzy: Katharina Mauel, Daria Hirschmann, Nelli Blank-Stein, Marie-Louise Diefenbach-Wilke, Theresa Eulgem, Shirley Le, Samuel N. Breit, Miguel P. Soares, Vicky Wang-Wei Tsai, Florent Ginhoux, William R. Heath, Lynette Beattie, Elvira Mass
Opublikowane w: Immunity, 2026, ISSN 1074-7613
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2026.07.006

From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists

Autorzy: Lea Seep, Stephan Grein, Iva Splichalova, Danli Ran, Mickel Mikhael, Staffan Hildebrand, Mario Lauterbach, Karsten Hiller, Dalila Juliana Silva Ribeiro, Katharina Sieckmann, Ronja Kardinal, Hao Huang, Jiangyan Yu, Sebastian Kallabis, Janina Behrens, Andreas Till, Viktoriya Peeva, Akim Strohmeyer, Johanna Bruder, Tobias Blum, Ana Soriano-Arroquia, Dominik Tischer, Katharina Kuellmer, Yuanfang Li, M
Opublikowane w: Scientific Data, Numer 11, 2026, ISSN 2052-4463
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s41597-024-03349-2

Tissue-specific macrophages: how they develop and choreograph tissue biology

Autorzy: Elvira Mass, Falk Nimmerjahn, Katrin Kierdorf & Andreas Schlitzer
Opublikowane w: Nature Reviews Immunology, 2023, ISSN 1474-1733
Wydawca: Nature Publishing Group
DOI: 10.1038/s41577-023-00848-y

Kupffer cell programming by maternal obesity triggers fatty liver disease

Autorzy: Hao Huang, Nora R. Balzer, Lea Seep, Iva Splichalova, Nelli Blank-Stein, Maria Francesca Viola, Eliana Franco Taveras, Kerim Acil, Diana Fink, Franzisca Petrovic, Nikola Makdissi, Seyhmus Bayar, Katharina Mauel, Carolin Radwaniak, Jelena Zurkovic, Amir H. Kayvanjoo, Klaus Wunderling, Malin Jessen, Mohamed H. Yaghmour, Lukas Kenner, Thomas Ulas, Stephan Grein, Joachim L. Schultze, Charlotte L. Scot
Opublikowane w: Nature, Numer 644, 2025, Strona(/y) 790-798, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-025-09190-w

Macrophage and monocyte subsets in response to ischemic stroke

Autorzy: Nelli Blank‐Stein, Elvira Mass
Opublikowane w: European Journal of Immunology, Numer 53, 2024, ISSN 0014-2980
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202250233

Kupffer cells control neonatal hepatic metabolism via Igf1 signaling

Autorzy: Nikola Makdissi, Daria J. Hirschmann, Aleksej Frolov, Inaam Sado, Bastian Bennühr, Fabian Nikolka, Jingyuan Cheng, Nelli Blank-Stein, Maria Francesca Viola, Mohamed Yaghmour, Philipp Arnold, Lorenzo Bonaguro, Matthias Becker, Christoph Thiele, Felix Meissner, Karsten Hiller, Marc D. Beyer, Elvira Mass
Opublikowane w: Development, Numer 153, 2026, ISSN 0950-1991
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/dev.204962

Differential impact of high-salt levels in vitro and in vivo on macrophage core functions

Autorzy: Linda Müller, Aya Rafea Nasr, Bettina Jux, Nikola Makdissi, Justin Wayne Trowbridge, Susanne V. Schmidt, Joachim L. Schultze, Thomas Quast, Jonas Schulte-Schrepping, Waldemar Kolanus, Elvira Mass
Opublikowane w: Molecular Biology Reports, Numer 343, 2024, Strona(/y) Volume 51, Numer 1, ISSN 1573-4978
Wydawca: Springer Nature
DOI: 10.21203/rs.3.rs-3768163/v1

Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease

Autorzy: Rudolfo Karl, Arsila Palliyulla Kariat Ashraf, Maria Francesca Viola, Katharina Hopp, Elvira Mass, Dagmar Wachten
Opublikowane w: Journal of Cell Science, Numer 138, 2025, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.263992

From macrophage biology to macrophage-based cellular immunotherapies

Autorzy: Elvira Mass, Nico Lachmann
Opublikowane w: Gene Therapy, Numer 28/9, 2021, Strona(/y) 473-476, ISSN 0969-7128
Wydawca: Nature Publishing Group
DOI: 10.1038/s41434-021-00221-5

Validation and refinement of existing methods for timed mating and early pregnancy detection in guinea pigs

Autorzy: Marina Luisa Mayer, Ilja Finkelberg, Elvira Mass
Opublikowane w: PLOS One, Numer 21, 2026, Strona(/y) e0347318, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0347318

Microglia and CD8+ T cell activation precede neuronal loss in a murine model of spastic paraplegia 15

Autorzy: Aleksej Frolov, Hao Huang, Dagmar Schütz, Maren Köhne, Nelli Blank-Stein, Collins Osei-Sarpong, Maren Büttner, Tarek Elmzzahi, Mukhran Khundadze, Marina Zahid, Michael Reuter, Matthias Becker, Elena De Domenico, Lorenzo Bonaguro, Axel Kallies, Helen Morrison, Christian A. Hübner, Kristian Händler, Ralf Stumm, Elvira Mass, Marc D. Beyer
Opublikowane w: Journal of Experimental Medicine, Numer 222, 2025, ISSN 0022-1007
Wydawca: Rockefeller University Press
DOI: 10.1084/jem.20232357

Developmental programming of tissue-resident macrophages

Autorzy: Maria Francesca Viola, Eliana Franco Taveras, Elvira Mass
Opublikowane w: Frontiers in Immunology, Numer 15, 2024, ISSN 1664-3224
Wydawca: Frontiers Media SA
DOI: 10.3389/fimmu.2024.1475369

Non-peer reviewed articles (1)

How much plastic is too much for our brain?

Autorzy: Elvira Mass
Opublikowane w: The Project Repository journal, Numer 6, 2020, Strona(/y) 8–11, ISSN 2632-4067
Wydawca: European Dissemination Media Agency

Book chapters (4)

Ontogeny and function of microglia and nerve-associated macrophages

Autorzy: Marina Mayer, Eliana Franco Taveras, Elvira Mass
Opublikowane w: Advances in Immunology, 2025, Strona(/y) 91-122
Wydawca: Elsevier
DOI: 10.1016/bs.ai.2025.04.002

The development and physiological and pathophysiological functions of resident macrophages and glial cells

Autorzy: Nelli Blank, Marina Mayer, Elvira Mass
Opublikowane w: Advances in Immunology volume 151, Numer 151, 2021, Strona(/y) 1-47, ISBN 9780128245996
Wydawca: Elsevier
DOI: 10.1016/bs.ai.2021.08.001

Fate-Mapping of Yolk Sac-Derived Macrophages

Autorzy: Iva Splichalova, Elvira Mass
Opublikowane w: Methods in Molecular Biology, Tissue-Resident Macrophages, 2023, Strona(/y) 129-137
Wydawca: Springer US
DOI: 10.1007/978-1-0716-3437-0_8

Fate-Mapping of Hematopoietic Stem Cell-Derived Macrophages

Autorzy: Katharina Mauel, Elvira Mass
Opublikowane w: Methods in Molecular Biology, Tissue-Resident Macrophages, 2023, Strona(/y) 139-148
Wydawca: Springer US
DOI: 10.1007/978-1-0716-3437-0_9

Conference proceedings (1)

THE IMPACT OF PLASTIC POLLUTION ON HUMAN NEURODEVELOPMENT AND NEUROINFLAMMATION

Autorzy: Nelli Blank-Stein, Marina L. Mayer, Maria Francesca Viola, Elvira Mass
Opublikowane w: GLIA (Meeting Abstract Supplement), Numer Volume 73, Supplement S1, 26. Juni 2025, 2025, Strona(/y) 852, ISSN 0894-1491
Wydawca: John Wiley & Sons, Inc.

Other (1)

Our plastic world – what does it mean for our health?

Autorzy: Marina Mayer, Nikola Makdissi, Maria Francesca Viola, Elvira Mass
Opublikowane w: The Project Repository Journal (PRj), Numer Volume 19, November 2023, 2023, ISSN 2632-4113
Wydawca: European Dissemination Media Agency (EDMA)