Safety in NanOmaterials & NAnotechnology

Informacje na temat projektu

SiNfONiA

Identyfikator umowy o grant: 857253

DOI

10.3030/857253

Projekt został zamknięty

Data podpisania przez KE 20 Czerwca 2019

Data rozpoczęcia 1 Czerwca 2019

Data zakończenia 31 Grudnia 2024

Finansowanie w ramach

• Establishing ‚ERA Chairs’

Koszt całkowity

€ 2 498 581,25

Wkład UE

€ 2 498 581,25

Koordynowany przez

INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY
Portugal

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Websites, patent fillings, videos etc. (5)

"SiNfONiA - Video #4"

Short video presenting the available throughput nanosafety assays at INL and identifuing potential uses and customers of such services. Short video no longer then 60'.

"SiNfONiA - Video #2"

Short video explaining the research focus of the Nanosofety research department at INL and the expected impacts of such research The video will be no longer then 60 an may rely on info graphics style

"SiNfONiA - Video #3"

Short video showing the main research outcomes of the Nanosafety reseacrh department at INL. Short video, no longer then 60'.

Dissemination kit

The dissemination kit will be composed by the following elements: - SiNfONiA project branding (incl. templates) - Press kit: presentation providing information about the project to be distributed to members of the media for promotional use - SiNfONiA brochure - Newsletter template First elements of the dissemination kit will be prepared by month 12 and will be further updated by month 24, 36, 48 and 60.

"SiNfONiA - Video #1"

Short video raising awareness about the nanosafety research topic and briefly introducing the nanosafety research department at INL Info grahics style may be used The video should be no longer then 60

Other (1)

Nanosafety digital platform

Web based tool for promoting networking, information sharing; for providing effective up-to-date data by on the ERA chair´s activities and for promoting collaborations at European and worldwide level. The digital platform will be a tool for linking the ERA Chair´s activities with all interested stakeholders and research communities in the nanosafety area. The platform will be open and all interested stakeholders can register.The platform will be integrated in the SiNfONiA web-site.

Publikacje

Peer reviewed articles (22)

Osteoblasts-derived exosomes as potential novel communicators in particle-induced periprosthetic osteolysis

Autorzy: Wanderson de Souza, S. Gemini-Piperni, Carolina Ruivo, Nuno Bastos, Sofia Almeida, Daniel Lopes, Patricia Cardoso, Maria Jose Oliveira, D. Rick Sumner, Ryan D. Ross, Joshua J. Jacobs, Jose Mauro Granjeiro, Maria Helena Fernandes, Luis A. Rocha, Sonia Melo, Ana R. Ribeiro
Opublikowane w: Materials Today Bio, Numer 28, 2024, Strona(/y) 101189, ISSN 2590-0064
Wydawca: ELSEVIER
DOI: 10.1016/j.mtbio.2024.101189

A Nano-QSTR model to predict nano-cytotoxicity: an approach using human lung cells data

Autorzy: João Meneses, Michael González-Durruthy, Eli Fernandez-de-Gortari, Alla P. Toropova, Andrey A. Toropov, Ernesto Alfaro-Moreno
Opublikowane w: Particle and Fibre Toxicology, Numer 20, 2023, ISSN 1743-8977
Wydawca: BioMed Central
DOI: 10.1186/s12989-023-00530-0

Titanium dioxide nanoparticles affect osteoblast-derived exosome cargos and impair osteogenic differentiation of human mesenchymal stem cells

Autorzy: Wanderson de Souza, S. Gemini-Piperni, Liliana Grenho, Luís A. Rocha, José M. Granjeiro, Sonia A. Melo, Maria H. Fernandes, Ana R. Ribeiro
Opublikowane w: Biomaterials Science, Numer 11, 2024, Strona(/y) 2427-2444, ISSN 2047-4830
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2bm01854c

Probabilistic material flow analysis of released nano titanium dioxide in Mexico

Autorzy: Luis Mauricio Ortiz-Galvez, Alejandro Caballero-Guzman, Carla Lopes, Ernesto Alfaro-Moreno
Opublikowane w: NanoImpact, Numer 35, 2025, Strona(/y) 100516, ISSN 2452-0748
Wydawca: ELSEVIER
DOI: 10.1016/j.impact.2024.100516

Particulate matter-induced oxidative stress – Mechanistic insights and antioxidant approaches reported in in vitro studies

Autorzy: Vânia Vilas-Boas, Nivedita Chatterjee, Andreia Carvalho, Ernesto Alfaro-Moreno
Opublikowane w: Environmental Toxicology and Pharmacology, Numer 110, 2024, Strona(/y) 104529, ISSN 1382-6689
Wydawca: Elsevier BV
DOI: 10.1016/j.etap.2024.104529

Decoding the conformational binding of drug mixtures on ovalbumin: An integrated multimodal network

Autorzy: Michael González-Durruthy, Ramón Rial, Juan M. Ruso
Opublikowane w: International Journal of Biological Macromolecules, Numer 261, 2024, Strona(/y) 129866, ISSN 0141-8130
Wydawca: Elsevier BV
DOI: 10.1016/j.ijbiomac.2024.129866

Nanomaterial exposure, extracellular vesicle biogenesis and adverse cellular outcomes: A Scoping Review

Autorzy: Thais SM Lima, Wanderson Souza, Luths RO Geaquinto, Priscila L Sanches, Ewa L Stepień, João Meneses, Eli Fernández-de Gortari, Nicole Meisner-Kober, Martin Himly, José M Granjeiro, Ana R Ribeiro
Opublikowane w: Nanomaterials, Numer 12, 2022, Strona(/y) 1231, ISSN 2079-4991
Wydawca: Basel: MDPI AG, 2011
DOI: 10.3390/nano12071231

Exploring the immunomodulatory properties of glucan particles in human primary cells

Autorzy: Sandra Jesus, João Panão Costa, Mariana Colaço, Filipa Lebre, Daniela Mateus, Ana Isabel Sebastião, Maria T. Cruz, Ernesto Alfaro-Moreno, Olga Borges
Opublikowane w: International Journal of Pharmaceutics, Numer 655, 2024, Strona(/y) 123996, ISSN 0378-5173
Wydawca: Elsevier BV
DOI: 10.1016/j.ijpharm.2024.123996

Enhancing Transcutaneous Drug Delivery: Advanced Perspectives on Skin Models

Autorzy: Ana Ribeiro, Catarina Pereira-Leite, Catarina Rosado, Edlira Aruci, Helen E. Colley, Inge Kortekaas Krohn, Ioana Baldea, Ivana Pantelić, Joachim W. Fluhr, Sandra I. Simões, Snežana Savić, Sofia A. Costa Lima
Opublikowane w: JID Innovations, Numer 5, 2025, Strona(/y) 100340, ISSN 2667-0267
Wydawca: ELSEVIER
DOI: 10.1016/j.xjidi.2024.100340

Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials

Autorzy: S. Costa, V. Vilas-Boas, F. Lebre, J.M. Granjeiro, C.M. Catarino, L. Moreira Teixeira, P. Loskill, E. Alfaro-Moreno, A.R. Ribeiro
Opublikowane w: Trends in Biotechnology, Numer 41, 2024, Strona(/y) 1282-1298, ISSN 0167-7799
Wydawca: Elsevier BV
DOI: 10.1016/j.tibtech.2023.05.009

Eco‐Friendly Production of 2D Ti₃C₂T_x MXene and Cytotoxicity Mitigation Toward Biomedical Applications

Autorzy: Siva Nemala Sankar, Guilherme Araujo, João Fernandes, Fatima Cerqueira, Pedro Alpuim, Ana R. Ribeiro, Filipa Lebre, Ernesto Alfaro‐Moreno, Ernesto Placidi, Sergio Marras, Andrea Capasso
Opublikowane w: Advanced Materials Interfaces, Numer 11, 2024, Strona(/y) 24, ISSN 2196-7350
Wydawca: Wiley
DOI: 10.1002/admi.202400203

Effect of NaOH etching and oxygen plasma treatments on surface characteristics and their potential to activate micro-arc oxidized TiO2 coatings

Autorzy: Natália A. Costa, Ana R. Ribeiro, André L. Rossi, Cláudia Monteiro, Paulo N. Lisboa-Filho, M. Cristina L. Martins
Opublikowane w: Applied Surface Science, Numer 682, 2024, Strona(/y) 161748, ISSN 0169-4332
Wydawca: Elsevier BV
DOI: 10.1016/j.apsusc.2024.161748

Nanosafety: An Evolving Concept to Bring the Safest Possible Nanomaterials to Society and Environment

Autorzy: Filipa Lebre; Nivedita Chatterjee; Samantha Costa; Eli Fernández-de-Gortari; Carla Lopes; João Meneses; Luís Ortiz; Ana R. Ribeiro; Vânia Vilas-Boas; Ernesto Alfaro-Moreno
Opublikowane w: Nanomaterials, Numer 12, 2022, ISSN 2079-4991
Wydawca: Basel: MDPI AG, 2011
DOI: 10.3390/nano12111810

Pre-validation of a novel reconstructed skin equivalent model for skin irritation and nanoparticle risk assessment

Autorzy: Priscila Laviola Sanches, Rosana Bizon Vieira Carias, Gutember Gomes Alves, Carolina Motter Catarino, Bruna Bosquetti, Meg Cristina De Castilho Costa, Andrezza Di Pietro Micali, Desirée Cigaran Schuck, José Mauro Granjeiro, Ana R. Ribeiro
Opublikowane w: Nanoscale Advances, Numer 7, 2025, Strona(/y) 1353-1367, ISSN 2516-0230
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d4na00804a

Effects of chemical <i>in vitro</i> activation versus fragmentation on human ovarian tissue and follicle growth in culture

Autorzy: Jie Hao, Tianyi Li, Manuel Heinzelmann, Elisabeth Moussaud-Lamodière, Filipa Lebre, Kaarel Krjutškov, Anastasios Damdimopoulos, Catarina Arnelo, Karin Pettersson, Ernesto Alfaro-Moreno, Cecilia Lindskog, Majorie van Duursen, Pauliina Damdimopoulou
Opublikowane w: Human Reproduction Open, Numer 2024, 2024, ISSN 2399-3529
Wydawca: Oxford Academic
DOI: 10.1093/hropen/hoae028

Differential impact of diesel exhaust particles on glutamatergic and dopaminergic neurons in Caenorhabditis elegans: A neurodegenerative perspective

Autorzy: Nivedita Chatterjee, Michael González-Durruthy, Marta Daniela Costa, Ana R. Ribeiro, Vânia Vilas-Boas, Daniela Vilasboas-Campos, Patrícia Maciel, Ernesto Alfaro-Moreno
Opublikowane w: Environment International, Numer 186, 2024, Strona(/y) 108597, ISSN 0160-4120
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2024.108597

In Vitro Cell Transformation Assays: A Valuable Approach for Carcinogenic Potentiality Assessment of Nanomaterials

Autorzy: Nivedita Chatterjee, Ernesto Alfaro-Moreno
Opublikowane w: International Journal of Molecular Sciences, Numer 24, 2023, Strona(/y) 8219, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24098219

The Effects of Titanium Dioxide Nanoparticles on Osteoblasts Mineralization: A Comparison between 2D and 3D Cell Culture Models

Autorzy: Gabriela de Souza Castro, Wanderson de Souza, Thais Suelen Mello Lima, Danielle Cabral Bonfim, Jacques Werckmann, Braulio Soares Archanjo, José Mauro Granjeiro, Ana Rosa Ribeiro, Sara Gemini-Piperni
Opublikowane w: Nanomaterials, Numer 13, 2025, Strona(/y) 425, ISSN 2079-4991
Wydawca: DOAJ
DOI: 10.3390/nano13030425

Ambient black carbon particles in human ovarian tissue and follicular fluid

Autorzy: Eva Bongaerts, Katariina Mamia, Ilmatar Rooda, Richelle D. Björvang, Kiriaki Papaikonomou, Sebastian B. Gidlöf, Jan I. Olofsson, Marcel Ameloot, Ernesto Alfaro-Moreno, Tim S. Nawrot, Pauliina Damdimopoulou
Opublikowane w: Environment International, Numer 179, 2024, Strona(/y) 108141, ISSN 0160-4120
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.108141

Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro

Autorzy: Eleftheria Maria Panagiotou, Anastasios Damdimopoulos, Tianyi Li, Elisabeth Moussaud-Lamodière, Mikael Pedersen, Filipa Lebre, Karin Pettersson, Catarina Arnelo, Kiriaki Papaikonomou, Ernesto Alfaro-Moreno, Cecilia Lindskog, Terje Svingen, Pauliina Damdimopoulou
Opublikowane w: Toxicology, Numer 505, 2025, Strona(/y) 153815, ISSN 0300-483X
Wydawca: Elsevier BV
DOI: 10.1016/j.tox.2024.153815

Dhvar5- and MSI78-coated titanium are bactericidal against methicillin-resistant Staphylococcus aureus, immunomodulatory and osteogenic

Autorzy: B. Costa, J. Coelho, V. Silva, H. Shahrour, N.A. Costa, A.R. Ribeiro, S.G. Santos, F. Costa, G. Martínez-de-Tejada, C. Monteiro, M.C.L. Martins
Opublikowane w: Acta Biomaterialia, Numer 191, 2024, Strona(/y) 98-112, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2024.11.016

The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions

Autorzy: Alla P Toropova, João Meneses, Ernesto Alfaro-Moreno, Andrey A Toropov
Opublikowane w: Drug and Chemical Toxicology, Numer 04, 2023, ISSN 0148-0545
Wydawca: Marcel Dekker Inc.
DOI: 10.1080/01480545.2023.2174986

Thesis and dissertations (3)

Estimation of probable environmental concentrations of released titanium dioxide nanoparticles in Mexico

Autorzy: Luis Mauricio Ortiz Galvez
Opublikowane w: MAster Thesis, 2022
Wydawca: University of the Basque Country (UPV/EHU)

Modulation of cellular responses mediated by extracellular vesicles mediated by nanomaterials

Autorzy: Thaís Suelen Mello Lima
Opublikowane w: 2021
Wydawca: National Institute of Metrology Quality and Technology

Development of a skin-on-a-chip device for toxicological evaluation of nanomaterials

Autorzy: Samantha Faria da Costa Oliveira
Opublikowane w: Numer 1, 2022
Wydawca: Universidade

Monographic books (1)

tbd

Autorzy: Nivedita Chatterjee, Vânia Vilas-Boas, Filipa Lebre, Ana R. Ribeiro, S. Costa, S. Nogueira, M González-Durruthy, H. Coley, N. Oliva, R. De Vecchi, E. Alfaro-Moreno
Opublikowane w: Nanosafety: A Comprehensive Approach to Assess Nanomaterial Exposure on the Environment and Health, Numer 2025, 2025, Strona(/y) all
Wydawca: Springer Nature