CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.
Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .
Rezultaty
This deliverable will describe a detailed Project Management Plan with a Gantt chart and a Work Breakdown Structure (WBS). It wil include a schedule per task, responsible partner related subtasks, related deliverables, and dependencies on other tasks.
Report on areosol and UFPs characteristics from high performance engines (odnośnik otworzy się w nowym oknie)This deliverable will describe the results concerning the chemical and physical characterization of exhaust emissions from high-power engines. The deliverable will include information on primary and aged aerosols and UFPs from the exhaust of a ship diesel engine, a medium duty gas engine and the jet engine combustor test rig.
Report on mechanisms of effects from transport mode emissions (odnośnik otworzy się w nowym oknie)"This deliverable will report on the mechanisms of adverse effects from transport mode emissions, and what emission characteristics are the main drivers of biological effects, icluding the importance of the ""Torjan Horse"" effect. The deliverable will be based on predictions made from biostatistical analysis in T6.1, whihc will be further tested and validated in T6.2 and T6.3."
Training materials and equal opportunity measures (odnośnik otworzy się w nowym oknie)This deliverable will present to the Commission the overall plan for a winter/summer school for early stage researchers. Including a list of invited speakers and presenters and subjects to be covered in the programme, as well as a strategy for reqruitment of students of both genders according to wider equality considerations.
Report on in vivo effects of atmospheric aging (odnośnik otworzy się w nowym oknie)This deliverable will report the in vivo findings caused by atmospheric aging, by using selected aerosol sources in aging studies. The deliverable will provide comparative information on lung and secondary organ effects for validation of in vitro models.
Report on sex-related differences in selected secondary tissue models (odnośnik otworzy się w nowym oknie)This deliverable will report on sex-related differences in secondary organ tissue. The deliverable will include information on effects in models composed with primary cells from female vs. male donors exposed directly or indirectly to UFPs / supernatants from different sources.
Report on importance of sex for in vivo effects transport emissions (odnośnik otworzy się w nowym oknie)In this deliverable, we provide information on how sex-related differences affect the sensitivity to transport emission exposure. Selected aersol sources will be used in this approach and the results will be assessed for further validation of the health effects and link the results to D5.1 and D5.2.
Report on model aerosols and UFPs characteristics for testing of hypotheses and Trojan horse effects (odnośnik otworzy się w nowym oknie)This deliverable will elucidate the role of cellular sensors of organic chemicals and redox sensitive pathways using in vitro tests with model UFPs. In addition the results on the investigation of the Trojan horse effect of UFPs will be described.
Report on particles/ particle components and cell mediators (odnośnik otworzy się w nowym oknie)This deliverable will provide a complete characterization of conditioned cell culture medium from CAST generated particles exposed lung tissues The deliverable will include information on UFP translocation particle adhered chemicals and cytokine chemokines released by lung cells
Characterization of selected policies (odnośnik otworzy się w nowym oknie)This delivery will describe a set of inter- and intrasectional transportation policy options that have been selected for health benefit analysis. The selection is based on hazard and exposure ranking of the emissions that the policy will impact. Description of the policies will include, among others, a priori assumptions, selection criteria and changes in emissions.
Report on direct vs. indirect effects on human intestine tissue (odnośnik otworzy się w nowym oknie)This deliverable will report on inflammatory and genotoxic effects of UFPs in intestinal tissue. The deliverable will include information on 3D cultures of human intestine cultures exposed directly to CAST generated particles or to conditioned medium from particle exposed lung tissue.
Report on high-power engine emission and aging on lung tissue models (odnośnik otworzy się w nowym oknie)This deliverable will report on the biological effects of ehaust emisssions from high-power engine in lung tissue. The deliverable will include infomation on bothy primary and aged aerosols and UFPs on (geno)toxicological outcomes in in vitro ALI models.
Report on ALI-based in vitro inhalation toxicity testing strategy for multi-tissue effects, validated by in vivo studies (odnośnik otworzy się w nowym oknie)This deliverable will optimize the protocols to evaluate effects in secondary organ tissue models using supernatans from lung tissues exposed to CAST generated particles. The deliverable will apply the protocols to compare indirect effects of supernatants collected from different source-exposed lung-tissues in secondary organ tissue models.
Report on areosol and UFPs characteristics from non-exhaust sources (odnośnik otworzy się w nowym oknie)This deliverable will report on the results concerning the chemical and physical characterization of non-exhaust esmissions from transport modes. The deliverable will include information on aerosols and UFPs from vehicle brake emissions and rail caternary sparkling.
Report on in vivo validation of in vitro biological effects (odnośnik otworzy się w nowym oknie)This deliverable will report the findings from in vivo exposures with different aerosol sources and compare them with the gathered information on the in vitro expereriments. The information will be used for reporting the validity of in vitro findings in whole organism, to build a link to health effects by the exhaust aerosol UFPs.
Report on CAST-generated UFP effects (odnośnik otworzy się w nowym oknie)This deliverable will report on dosymetry considerations and chemical composition related to both primary and secondary (geno)toxicological effects of UFPs. The deliverable will provide information on CAST-generated model emisssions in lung tissue models at ALI.
Report on final event, scientific publications and project results (odnośnik otworzy się w nowym oknie)This deliverable will report the final list of scientific publications in peer-reviewed journals derived from and acknowledging the EC support to the project, the most relevant communications to scientific meetings. The deliverable will also include completed exploitation activities e.g. pertinent innovation, marketing and dissemination actions and/or tools to interested stakeholders will be reported.
Exploitation plan (odnośnik otworzy się w nowym oknie)This deliverable will report on exploitation activities involving reaching out to, and building collaborations with, key experts, external organisations. The deliverable will describe end-users.
Report on mechanical generated UFP effects (odnośnik otworzy się w nowym oknie)This deliverable will report on the biological effects of non-exhaust transport mode emissions in lung tissue. The deliverable will include infomation on effects of UFPs and metals/metal ions on (geno)toxicological outcomes in in vitro ALI models.
IPR & Innovation Strategy (odnośnik otworzy się w nowym oknie)This deliverable will present to the Commision innovation potential identified on the background of findings and a strategy for innvolvement of potential extnal parties in innovation exploitiationThe IPR strategy will include both preexisting knowledge and knowledge generated in this project
Report on areosol and UFPs characteristics from light duty vehicles (odnośnik otworzy się w nowym oknie)This deliverable will describe the results concerning the chemical and physical characterization of exhaust emissisons from light-duty engines. The deliverable will include information on primary and aged aerosols and UFPs from the exhaust of gasoline and diesel engines.
Hazard ranking of transport modes (odnośnik otworzy się w nowym oknie)This deliverable will report on the hazard ranking of the transport mode emissions tested, by combining to emission characteristics from WP2, with the biological/toxicological effects reported from WP3, WP4, and WP5. The report will provide information on, and compare, the relative hazards of differrent transport mode emissions, including the impact of athmospheric ageing. D6.2 will be based on activities in T6.1.
Report on light-duty vehicle emission and aging effects (odnośnik otworzy się w nowym oknie)This deliverable will report on the biological effects of ehaust emisssions from light-duty engine in lung tissue. The deliverable will include infomation on bothy primary and aged aerosols and UFPs on (geno)toxicological outcomes in in vitro ALI models.
Project Management Plan- first update (odnośnik otworzy się w nowym oknie)Fist update of a detailed Project Management Planwith a Gantt chart and a Work Breakdown Structure WBS It wil include a schedule per task responsible partner related subtasks related deliverables and dependencies on other tasks
Project CD plan and website (odnośnik otworzy się w nowym oknie)Communication and dissemination (CD) strategy and plan will describe target audiences, key messages for each stakeholder and the use of different channels and tools for management and monitoring of effective and efficient CD activities. The project website will in addition encompass internal consortium communication .
Project Management Plan- second update (odnośnik otworzy się w nowym oknie)Second update of a detailed Project Management Plan with a Gantt chart and a Work Breakdown Structure (WBS). It wil include a schedule per task, responsible partner related subtasks, related deliverables, and dependencies on other tasks.
This deliverable will describe the Scientific Advisory Board's mandate. The deliverable will also include a list of the SAB-members and their expertise.
Publikacje
Autorzy:
Antti Korhonen, Isabell Katharina Rumrich, Marjut Roponen, Lise M. Frohn, Camilla Geels, Jørgen Brandt, Anna-Maija Tolppanen, Otto Hänninen
Opublikowane w:
Science of The Total Environment, Numer 954, 2024, Strona(/y) 176422, ISSN 0048-9697
Wydawca:
Elsevier BV
DOI:
10.1016/j.scitotenv.2024.176422
Autorzy:
Gowsinth Gunasingam; Ruiwen HE; Patricia Taladriz-Blanco; Sandor Balog; Alke Petri-Fink; Barbara Rothen-Rutishauser
Opublikowane w:
Particle and Fibre Toxicology, Numer 21:26, 2024, 2024, ISSN 1743-8977
Wydawca:
BioMed Central
DOI:
10.1186/s12989-024-00585-7
Autorzy:
Eric Schneider, Hendryk Czech, Anni Hartikainen, Helly J. Hansen, Nadine Gawlitta, Mika Ihalainen, Pasi Yli-Pirilä, Markus Somero, Miika Kortelainen, Juho Louhisalmi, Jürgen Orasche, Zheng Fang, Yinon Rudich, Olli Sippula, Christopher P. Rüger, Ralf Zimmermann
Opublikowane w:
Environmental Science: Processes & Impacts, Numer 26, 2024, Strona(/y) 1295-1309, ISSN 2050-7887
Wydawca:
Royal Society of Chemistry
DOI:
10.1039/d4em00106k
Autorzy:
Jørn A. Holme, Jan Vondráček, Miroslav Machala, Dominique Lagadic-Gossmann, Christoph F.A. Vogel, Eric Le Ferrec, Lydie Sparfel, Johan Øvrevik
Opublikowane w:
Biochemical Pharmacology, Numer 216, 2024, Strona(/y) 115801, ISSN 0006-2952
Wydawca:
Elsevier BV
DOI:
10.1016/j.bcp.2023.115801
Autorzy:
Jan Bendl, Carsten Neukirchen, Ajit Mudan, Sara Padoan, Ralf Zimmermann, Thomas Adam
Opublikowane w:
Atmospheric Environment, Numer 308, 2023, Strona(/y) 119883, ISSN 1352-2310
Wydawca:
Elsevier BV
DOI:
10.1016/j.atmosenv.2023.119883
Autorzy:
Anusmita Das, Jana Pantzke, Seongho Jeong, Elena Hartner, Elias J. Zimmermann, Nadine Gawlitta, Svenja Offer, Deeksha Shukla, Anja Huber, Narges Rastak, Arūnas Meščeriakovas, Natalia P. Ivleva, Evelyn Kuhn, Stephanie Binder, Thomas Gröger, Sebastian Oeder, Mathilde Delaval, Hendryk Czech, Olli Sippula, Jürgen Schnelle-Kreis, Sebastiano Di Bucchianico, Martin Sklorz, Ralf Zimmermann
Opublikowane w:
Science of The Total Environment, Numer 951, 2024, Strona(/y) 175727, ISSN 0048-9697
Wydawca:
Elsevier BV
DOI:
10.1016/j.scitotenv.2024.175727
Autorzy:
Jørn A. Holme, Oddvar Myhre, Johan Øvrevik
Opublikowane w:
Reproductive Toxicology, Numer 130, 2024, Strona(/y) 108718, ISSN 0890-6238
Wydawca:
Elsevier BV
DOI:
10.1016/j.reprotox.2024.108718
Autorzy:
Henri Hakkarainen, Anssi Järvinen, Teemu Lepistö, Niina Kuittinen, Lassi Markkula, Tuukka Ihantola, Mo Yang, Maria-Viola Martikainen, Santtu Mikkonen, Hilkka Timonen, Minna Aurela, Luis Barreira, Mika Ihalainen, Sanna Saarikoski, Topi Rönkkö, Päivi Aakko-Saksa, Pasi Jalava
Opublikowane w:
Environmental Science: Atmospheres, Numer 4, 2024, Strona(/y) 455-467, ISSN 2634-3606
Wydawca:
Royal Society of Chemistry
DOI:
10.1039/d3ea00136a
Autorzy:
Carsten Neukirchen, Thorsten Meiners, Jan Bendl, Ralf Zimmermann, Thomas Adam
Opublikowane w:
Science of The Total Environment, Numer 915, 2024, Strona(/y) 170008, ISSN 0048-9697
Wydawca:
Elsevier BV
DOI:
10.1016/j.scitotenv.2024.170008
Autorzy:
Vegard Sæter Grytting, Tonje Skuland, Jarle Ballangby, Magne Refsnes, Marit Låg, Johan Øvrevik, Espen Mariussen
Opublikowane w:
Toxicology in Vitro, Numer 98, 2024, Strona(/y) 105841, ISSN 0887-2333
Wydawca:
Elsevier BV
DOI:
10.1016/j.tiv.2024.105841
Autorzy:
Jana Pantzke, Anusmita Das, Elias J Zimmermann, Svenja Offer, Seongho Jeong, Mathilde N Delaval, Jürgen Schnelle-Kreis, Martin Sklorz, Sebastiano Di Bucchianico, Ralf Zimmermann
Opublikowane w:
Annals of Work Exposures and Health, Numer 67, 2023, Strona(/y) i93-i93, ISSN 2398-7308
Wydawca:
Oxford Academic
DOI:
10.1093/annweh/wxac087.227
Autorzy:
Antti Korhonen, Heli Lehtomäki, Isabell Rumrich, Marjut Roponen, Anette Bølling, Gunn Marit Aasvang, Pasi Jalava, Barbara Rothen-Rutishauser, Sebastiano Di Bucchianico, Ralf Zimmermann, Johan Øvrevik, Otto Hänninen
Opublikowane w:
Annals of Work Exposures and Health, Numer 67, 2023, Strona(/y) i78-i79, ISSN 2398-7308
Wydawca:
Oxford Academic
DOI:
10.1093/annweh/wxac087.190
Autorzy:
Mathilde N Delaval, Hendryk Czech, Mohammad Almasaleekh, Svenja Offer, Mika Ihalainen, Pasi Yli-Pirilä, Thorsten Hohaus, Markus Kalberer, Sebastiano Di Bucchianico, Olli Sippula, Yinon Rudich, Ralf Zimmermann, null null
Opublikowane w:
Annals of Work Exposures and Health, Numer 67, 2023, Strona(/y) i69-i69, ISSN 2398-7308
Wydawca:
Oxford Academic
DOI:
10.1093/annweh/wxac087.166
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