Cel Some strains of lactic acid bacteria secrete antimicrobial peptides which could be used as natural preservatives in food and feed fermentations. These so-called bacteriocins are secreted via a dedicated sec-independent secretion system consisting of (at least) two proteins. The aim of the project is to unravel the mechansim of bacteriocin secretion by determining the specificity of and the interaction between the two components of the transport system. By reciprocally exchanging the four proteins involved in the secretion of lactococcin A and pediocin PA- I, the specificity of both transport systems will be unravelled. By making protein fusions and by isolating antibodies against the proteins under study, the interaction between the proteins of each system will be analyzed. Various mutation/complementation strategies will further pinpoint the interacting domains. Dziedzina nauki natural scienceschemical sciencesorganic chemistryorganic acidsnatural sciencesbiological sciencesmicrobiologybacteriologynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencesgeneticsmutationengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Program(-y) FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998 Temat(-y) 0302 - Post-doctoral research training grants TL16 - Biotechnology Zaproszenie do składania wniosków Data not available System finansowania RGI - Research grants (individual fellowships) Koordynator Rijksuniversiteit Groningen Wkład UE Brak danych Adres 30,Kerklaan 9751 NN Haren Niderlandy Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko Not available Włochy Wkład UE Brak danych Adres Zobacz na mapie Koszt całkowity Brak danych
