Innovations to accelerate vaccine development and manufacture

Informacje na temat projektu

Inno4Vac

Identyfikator umowy o grant: 101007799

DOI

10.3030/101007799

Data podpisania przez KE 19 Lipca 2021

Data rozpoczęcia 1 Września 2021

Data zakończenia 28 Lutego 2027

Finansowanie w ramach

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Koszt całkowity

€ 39 342 552,00

Wkład UE

€ 18 600 000,00

Koordynowany przez

EUROPEAN VACCINE INITIATIVE E.V
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (6)

Scientific consensus docon new challenge influenza strains
Roadmap document prioritizing RSV immune assays for development and standardization
Report of regulatory workshop 1
Prepare SOPs for handling open calls process
Workshops with stakeholders implemented
Open call process launched

Other (1)

Launch of web site

Publikacje

Non-peer reviewed articles (4)

Training data composition determines machine learning generalization and biological rule discovery

Autorzy: Eugen Ursu, Aygul Minnegalieva, Puneet Rawat, Maria Chernigovskaya, Robi Tacutu, Geir Kjetil Sandve, Philippe A. Robert, Victor Greiff
Opublikowane w: bioRxiv, 2024, ISSN 2692-8205
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.06.17.599333

Simulation of adaptive immune receptors and repertoires with complex immune information to guide the development and benchmarking of AIRR machine learning

Autorzy: Maria Chernigovskaya, Milena Pavlović, Chakravarthi Kanduri, Sofie Gielis, Philippe A. Robert, Lonneke Scheffer, Andrei Slabodkin, Ingrid Hobæk Haff, Pieter Meysman, Gur Yaari, Geir Kjetil Sandve, Victor Greiff
Opublikowane w: bioRxiv, 2023, ISSN 2692-8205
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.10.20.562936

Weakly supervised identification and generation of adaptive immune receptor sequences associated with immune disease status

Autorzy: Andrei Slabodkin, Ludvig M. Sollid, Geir Kjetil Sandve, Philippe A. Robert, Victor Greiff
Opublikowane w: bioRxiv, 2024, ISSN 2692-8205
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.09.24.558823

InSilicoSeq 2.0: Simulating realistic amplicon-based sequence reads

Autorzy: Stefan H. Lelieveld, Thijs Maas, Tessa C. X. Duk, Hadrien Gourlé, Henk-Jan van den Ham
Opublikowane w: bioRxiv, 2024, ISSN 2692-8205
Wydawca: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.02.16.580469

Other (2)

modsim/CADET: Version 4.4.0

Autorzy: Samuel Leweke, Johannes Schmölder, Eric von Lieres, Jayghosh Rao, Jazib Hassan, William Heymann, Jan Breuer, Jonathan Rocher, & Salah Azzouzi
Opublikowane w: 2023, ISSN 1082-9873
Wydawca: Zenodo
DOI: 10.5281/zenodo.8179016

Advancing In Silico Tools for Vaccine Development and Process Modeling

Autorzy: Irina Meln, Gunnveig Grødeland, Daniel G. Bracewell, Meta Roestenberg, Cécile van Els, Kimberly Veenstra and Ole Olesen
Opublikowane w: BioProcess International, 2022
Wydawca: Informa Connect Limited

Peer reviewed articles (11)

Fourth Controlled Human Infection Model (CHIM) meeting – CHIMs in endemic countries, May 22–23, 2023

Autorzy: Melissa Kapulu, Lucinda Manda-Taylor, Shobana Balasingam, Gary Means, Mikal Ayiro Malungu, Philip Bejon, Primus Che Chi, Christopher Chiu, E. Chandler Church, Rodrigo Correa-Oliveira, Nicholas Day, Anna Durbin, Moses Egesa, Claudia Emerson, Kondwani Jambo, Roli Mathur, Wolfram Metzger, Noni Mumba, Winfred Nazziwa, Ally Olotu, Jacqueline Rodgers, Frank Sinyiza, Kawsar Talaat, Ingrid Kamerling, Char
Opublikowane w: Biologicals, Numer 85, 2024, Strona(/y) 101747, ISSN 1045-1056
Wydawca: Academic Press
DOI: 10.1016/j.biologicals.2024.101747

Solving crystallization/precipitation population balance models in CADET, part I: Nucleation growth and growth rate dispersion in batch and continuous modes on nonuniform grids

Autorzy: Wendi Zhang, Todd Przybycien, Johannes Schmölder, Samuel Leweke, Eric von Lieres
Opublikowane w: Computers & Chemical Engineering, Numer 183, 2024, Strona(/y) 108612, ISSN 0098-1354
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.compchemeng.2024.108612

Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling

Autorzy: Khang Lê Quý, Maria Chernigovskaya, Maria Stensland, Sachin Singh, Jinwoo Leem, Santiago Revale, David A. Yadin, Francesca L. Nice, Chelsea Povall, Danielle H. Minns, Jacob D. Galson, Tuula A. Nyman, Igor Snapkow, Victor Greiff
Opublikowane w: npj Systems Biology and Applications, Numer 10, 2024, ISSN 2056-7189
Wydawca: Springer Nature
DOI: 10.1038/s41540-024-00402-z

Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability

Autorzy: Habib Bashour, Eva Smorodina, Matteo Pariset, Jahn Zhong, Rahmad Akbar, Maria Chernigovskaya, Khang Lê Quý, Igor Snapkow, Puneet Rawat, Konrad Krawczyk, Geir Kjetil Sandve, Jose Gutierrez-Marcos, Daniel Nakhaee-Zadeh Gutierrez, Jan Terje Andersen, Victor Greiff
Opublikowane w: Communications Biology, Numer 7, 2024, ISSN 2399-3642
Wydawca: Springer Nature
DOI: 10.1038/s42003-024-06561-3

Organ-on-chip models for infectious disease research

Autorzy: Raquel Alonso-Roman, Alexander S. Mosig, Marc Thilo Figge, Kai Papenfort, Christian Eggeling, Felix H. Schacher, Bernhard Hube, Mark S. Gresnigt
Opublikowane w: Nature Microbiology, Numer 9, 2024, Strona(/y) 891-904, ISSN 2058-5276
Wydawca: Nature Microbiology
DOI: 10.1038/s41564-024-01645-6

Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities

Autorzy: Elham Ramin, Antonio Gaetano Cardillo, Reinhard Liebers, Johannes Schmölder, Eric von Lieres, Wim Van Molle, Bastian Niebel, Laurent Natalis, Irina Meln, Mónica Perea-Vélez, Didier Clénet, John Bagterp Jørgensen, Bernt Nilsson, Daniel G. Bracewell, Krist V. Gernaey
Opublikowane w: Current Opinion in Chemical Engineering, Numer 43, 2024, Strona(/y) 100998, ISSN 2211-3398
Wydawca: Elsevier BV
DOI: 10.1016/j.coche.2023.100998

Regulatory workshop on challenge strain development and GMP manufacture – A stakeholder meeting report

Autorzy: Nicoletta Corti, Christopher Chiu, Rebecca J. Cox, Clarisse Demont, Jeanne-Marie Devaster, Othmar G. Engelhardt, Andrew Gorringe, Khaole Hassan, Marcel Hoefnagel, Ingrid Kamerling, Oleg Krut, Chelsea Lane, Reinhard Liebers, Catherine Luke, Wim Van Molle, Sandra Morel, Pieter Neels, Meta Roestenberg, Michelle Rubbrecht, Wiep Klaas Smits, Daniel Stoughton, Kawsar Talaat, Maria J.G.T. Vehreschild, Ad
Opublikowane w: Biologicals, Numer 85, 2024, Strona(/y) 101746, ISSN 1045-1056
Wydawca: Academic Press
DOI: 10.1016/j.biologicals.2024.101746

Ethical approval for controlled human infectious model clinical trial protocols – A workshop report

Autorzy: Euzebiusz Jamrozik, Katherine Littler, Irina Meln, Wim Van Molle, Sandra Morel, Ole F. Olesen, Michelle Rubbrecht, Shobana Balasingam, Pieter Neels
Opublikowane w: Biologicals, Numer 85, 2024, Strona(/y) 101748, ISSN 1045-1056
Wydawca: Academic Press
DOI: 10.1016/j.biologicals.2024.101748

Spatial discontinuous Galerkin spectral element method for a family of chromatography models in CADET

Autorzy: Jan Michael Breuer, Samuel Leweke, Johannes Schmölder, Gregor Gassner, Eric von Lieres
Opublikowane w: Computers & Chemical Engineering, 2023, Strona(/y) 108340, ISSN 0098-1354
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.compchemeng.2023.108340

Fourth Controlled Human Infection Model (CHIM) meeting, CHIM regulatory issues, May 24, 2023

Autorzy: Marco Cavaleri, David Kaslow, Eric Boateng, Wilbur H. Chen, Christopher Chiu, Robert K.M. Choy, Rodrigo Correa-Oliveira, Anna Durbin, Moses Egesa, Malick Gibani, Melissa Kapulu, Melba Katindi, Ally Olotu, Pongphaya Pongsuwan, Michelo Simuyandi, Bruno Speder, Kawsar R. Talaat, Charlie Weller, Bridget Wills, Marc Baay, Shobana Balasingam, Ole F. Olesen, Pieter Neels
Opublikowane w: Biologicals, Numer 85, 2024, Strona(/y) 101745, ISSN 1045-1056
Wydawca: Academic Press
DOI: 10.1016/j.biologicals.2024.101745

Immunocompetent PDMS‐Free Organ‐on‐Chip Model of Cervical Cancer Integrating Patient‐Specific Cervical Fibroblasts and Neutrophils

Autorzy: Elena Kromidas, Alicia Geier, Adrian Weghofer, Hui‐Yu Liu, Martin Weiss, Peter Loskill
Opublikowane w: Advanced Healthcare Materials, Numer 13, 2024, ISSN 2192-2640
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202302714