A PeRsOnalized Prevention roadmap for the future HEalThcare

Informacje na temat projektu

PROPHET

Identyfikator umowy o grant: 101057721

DOI

10.3030/101057721

Data podpisania przez KE 20 Maja 2022

Data rozpoczęcia 1 Września 2022

Data zakończenia 31 Sierpnia 2026

Finansowanie w ramach

• Health

Koszt całkowity

€ 2 812 437,50

Wkład UE

€ 2 812 437,00

Koordynowany przez

UNIVERSITA CATTOLICA DEL SACRO CUORE
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (10)

Report on data management and infrastructure requirements to bring research advances into Health Systems, outlining challenges and best practices

A summary of the data management needs, in alignment with the B1MG

List of process and outcome indicators for the evaluation of the clinical utility of personalized preventive approaches

Report with the list process and outcome indicators needed to evaluate the clinical utility of personalized preventive approaches

Report on biomarkers and digital technologies for risk prediction

A summary of the state of the art, opportunities & main gaps in biomarkers availability for precision prevention in the three selected areas & their integration with digital technologies for risk prediction and stratification.

Concept Paper on SRIA

A Concept Paper that include the preliminary concept towards SRIA.

Stakeholder Analysis

Analysis with stakeholder mapping and evaluation, required to the work related to D1.2

Report on clinical usefulness of biomarkers for personalized disease prevention

A summary of the evidence mapping on clinical usefulness of available biomarkers for precision prevention in the three selected areas.

Report on critical factors for the successful adoption of Personalized Prevention approaches by healthcare systems

A summary of findings from the literature mapping and survey to end users

Private sector and personal preventive information

Report on the role of the private sector, especially Direct-to-Consumer (DTC) companies, to produce personal preventive information and measures.

Report on current practices of citizens', patients', health professionals and policy makers engagement in Personalized Prevention and their gaps/bottleneck

A summary of the evidence mapping and desk research results.

Report on existing Research Programmes in the field of Personalized Prevention

A summary on existing Research programmes with a focus on the main obstacles in implementing and advancing research in the field of Personalized Prevention.

Other (1)

Stakeholder Platform

Release of the Forum, including explanation of roles, responsibilities, expectations, modus operandi

Websites, patent fillings, videos etc. (1)

Project Website

Website of the PROPHET project

Publikacje

Peer reviewed articles (13)

The current landscape of personalised preventive approaches for non-communicable diseases: A scoping review

Autorzy: Sara Farina, Tommaso Osti, Luigi Russo, Alessandra Maio, Nicolò Scarsi, Cosimo Savoia, Abdelrahman Taha, Leonardo Villani, Roberta Pastorino, Stefania Boccia
Opublikowane w: PLOS ONE, Numer 20, 2025, ISSN 1932-6203
Wydawca: Public Library of Science (PLoS)
DOI: 10.1371/JOURNAL.PONE.0317379

Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews

Autorzy: E Plans-Beriso, C Babb-de-Villiers, D Petrova, C Barahona-López, P Diez-Echave, O R Hernández, N F Fernández-Martínez, H Turner, E García-Ovejero, O Craciun, P Fernández-Navarro, N Fernández-Larrea, E García-Esquinas, I Kuhn, V Jiménez-Planet, V Moreno, F Rodríguez-Artalejo, M J Sánchez, M Pollan-Santamaria, L Blackburn, M Kroese, B Pérez-Gómez
Opublikowane w: Systematic Reviews, Numer 13, 2024, ISSN 2046-4053
Wydawca: Springer Science and Business Media LLC
DOI: 10.1186/S13643-024-02554-9

Scanning the horizon of personalized prevention research: an overview of ongoing European funded initiatives

Autorzy: Alessandra Maio, Sara Farina, Tommaso Osti, Salvatore Di Grande, Roberta Pastorino, Stefania Boccia
Opublikowane w: Frontiers in Public Health, Numer 13, 2025, ISSN 2296-2565
Wydawca: Frontiers Media SA
DOI: 10.3389/FPUBH.2025.1561328

Indicators of the clinical utility of genetic or genomic testing: a scoping review

Autorzy: A Valz Gris, A Pezzullo, T Diego, M Porcelli, M Di Pumpo, N Scarsi, null null, S Boccia
Opublikowane w: European Journal of Public Health, Numer 34, 2024, ISSN 1101-1262
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/EURPUB/CKAE144.1574

Barriers and facilitators for implementing a pharmacogenetic passport: lessons learned from reusing sequencing data

Autorzy: Anja H. A. Roelofsen, Loes Lindiwe Kreeftenberg, Carla G. van El, Lidewij Henneman, Tessel Rigter, Daoud Sie, Pierre M. Bet, Martina C. Cornel
Opublikowane w: Pharmacogenomics, Numer 26, 2025, ISSN 1462-2416
Wydawca: Informa UK Limited
DOI: 10.1080/14622416.2025.2504862

Biomarkers for Personalised Primary or Secondary Prevention in Cardiovascular Diseases: A Rapid Scoping Review

Autorzy: Chantal Babb de Villiers, Elena Plans-Beriso, Chaitanya Erady, Laura Blackburn, Hayley Wilson, Heather Turner, Isla Kuhn, Cristina Barahona-López, Paul Diez-Echave, Orlando Romulo Hernández, Nerea Fernández de Larrea-Baz, Dafina Petrova, Ramon Cierco Jimenez, Pablo Fernández-Navarro, Esther García-Esquinas, Fernando Rodríguez-Artalejo, María José Sánchez, Víctor Moreno, Marina Pollán, Beatriz Perez-Gomez, Mark Kroese
Opublikowane w: International Journal of Molecular Sciences, Numer 26, 2025, ISSN 1422-0067
Wydawca: MDPI AG
DOI: 10.3390/IJMS26199346

Sharing behavior and health care utilization following direct-to-consumer genetic testing: a systematic review

Autorzy: Eva Van Steijvoort, Kaatje Goossens, Kenji Demesure, Alexandra Stanczak, Maria Siermann, Pascal Borry
Opublikowane w: Open Research Europe, Numer 5, 2025, ISSN 2732-5121
Wydawca: F1000 Research Ltd
DOI: 10.12688/OPENRESEUROPE.19751.1

Engagement of patients and the public in personalised prevention in Europe using genomic information: a scoping review

Autorzy: Loes Lindiwe Kreeftenberg; Loes Lindiwe Kreeftenberg; Lidewij Henneman; Lidewij Henneman; Johannes C. F. Ket; Martina C. Cornel; Martina C. Cornel; Carla G. van El; Carla G. van El
Opublikowane w: Frontiers in Public Health, 2024, ISSN 2296-2565
Wydawca: Frontiers Media S.A
DOI: 10.3389/FPUBH.2024.1456853

Implementation of genetic tests for disease prevention: challenges in evidence synthesis across clinical utility domains

Autorzy: Angelica Valz Gris, Astrid M Vicente, Stefania Boccia
Opublikowane w: European Journal of Public Health, Numer 35, 2025, ISSN 1101-1262
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/EURPUB/CKAF047

The PROPHET project paves the way for personalized prevention in the future healthcare

Autorzy: Roberta Pastorino, Angelo Maria Pezzullo, Tommaso Osti, Roza Adany, Pascal Borry, Floris Barnhoorn, Eva Fadil, Mark Kroese, Andres Metspalu, Beatriz Perez-Gomez, Markus Perola, Daniela Quaggia, Serena Scollen, Mahsa Shabani
Opublikowane w: European Journal of Cancer Prevention, 2024, ISSN 0959-8278
Wydawca: Wolters Kluwer Health
DOI: 10.1097/CEJ.0000000000000873

Clinician perspectives on policy approaches to genetic risk disclosure in families

Autorzy: Amicia Phillips; Danya F. Vears; Ine Van Hoyweghen; Pascal Borry
Opublikowane w: Familial Cancer, 2023, ISSN 1573-7292
Wydawca: Springer Nature B.V.
DOI: 10.1007/S10689-024-00375-2

A scoping review of the assessment reports of genetic or genomic tests reveals inconsistent consideration of key dimensions of clinical utility

Autorzy: Angelo Maria Pezzullo, Angelica Valz Gris, Nicolò Scarsi, Diego Maria Tona, Martina Porcelli, Matteo Di Pumpo, Peter Piko, Roza Adany, Pragathy Kannan, Markus Perola, Maria Luis Cardoso, Alexandra Costa, Astrid M. Vicente, Anu Reigo, Mariliis Vaht, Andres Metspalu, Mark Kroese, Roberta Pastorino, Stefania Boccia
Opublikowane w: Journal of Clinical Epidemiology, Numer 181, 2025, ISSN 0895-4356
Wydawca: Elsevier BV
DOI: 10.1016/J.JCLINEPI.2025.111729

Lawfulness in secondary use of health data

Autorzy: Mahsa Shabani; Sami Yilmaz
Opublikowane w: Technology and Regulation, Vol 2022 (2022), 2022, ISSN 2666-139X
Wydawca: Open Press TiU
DOI: 10.26116/TECHREG.2022.013