Development of artificial phosphoinositides aiming at HIV eradication

Informacje na temat projektu

Super-HIPPO

Identyfikator umowy o grant: 101061939

DOI

10.3030/101061939

Projekt został zamknięty

Data podpisania przez KE 5 Sierpnia 2022

Data rozpoczęcia 1 Września 2023

Data zakończenia 31 Października 2025

Finansowanie w ramach

• Marie Skłodowska-Curie Actions (MSCA)

Koszt całkowity

Brak danych

Wkład UE

€ 148 478,40

Koordynowany przez

IZMIR KATIP CELEBI UNIVERSITESI
Türkiye

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Data Management Plan (1)

Data Management Plan

The research data of this project will generally be obtained from computer-based devices. Experimental and computational data of this project will be machine-retrievable and stored in these specialized devices and will be reusable when it is needed. The security of my project data will be ensured with codes and these computer-based devices will be maintained by the IT department of IKCU. When the findings of this project are published, digital object identifiers (DOIs) will be assigned to them. Publications will be accessible through the most important databases and trusted repositories.

Documents, reports (1)

Communication, Dissemination and Exploitation Plan

This project depends on creating strong synergy within various research disciplines. This means that significant advancements will also take place in the fields of drug synthesis, nanoparticle technology and biology. It is expected that the project will generate high quality publications, technological know‐how and IP (patents). It will thus have a scientific as well as industrial impact in the bio‐medical and pharmaceutical sectors, particularly in drug discovery and development. Therefore, the main direct result of my project will be the development of a drug candidate for HIV/AIDS that can be taken into the animal test, preclinical studies and then clinical trial phase.

Publikacje

Peer reviewed articles (6)

Design, Synthesis, and Mechanistic Anticancer Evaluation of New Pyrimidine-Tethered Compounds

Autorzy: Farida Reymova, Belgin Sever, Edanur Topalan, Canan Sevimli-Gur, Mustafa Can, Amaç Fatih Tuyun, Faika Başoğlu, Abdulilah Ece, Masami Otsuka, Mikako Fujita, Hasan Demirci, Halilibrahim Ciftci
Opublikowane w: Pharmaceuticals, Numer 18, 2025, ISSN 1424-8247
Wydawca: MDPI AG
DOI: 10.3390/PH18020270

Assessment of the anticancer function of <i>Coronilla orientalis</i> MILLER through comprehensive <i>in vitro</i> and computational studies

Autorzy: Halilibrahim Ciftci; Ayhan Oral; Yalcin Coskun; Gülin Renda; Masami Otsuka; Mikako Fujita; Belgin Sever
Opublikowane w: Turkish Journal of Biochemistry, 2025, ISSN 0250-4685
Wydawca: De Gruyter Brill
DOI: 10.1515/TJB-2024-0251

A Structural Insight Into Two Important ErbB Receptors (EGFR and HER2) and Their Relevance to Non‐Small Cell Lung Cancer

Autorzy: Edanur Topalan, Ahmet Büyükgüngör, Melih Çiğdem, Sinan Güra, Belgin Sever, Masami Otsuka, Mikako Fujita, Hasan Demirci, Halilibrahim Ciftci
Opublikowane w: Archiv der Pharmazie, Numer 358, 2025, ISSN 0365-6233
Wydawca: Wiley
DOI: 10.1002/ARDP.202400992

Structure and Dynamics of the ABL1 Tyrosine Kinase and Its Important Role in Chronic Myeloid Leukemia

Autorzy: Ayca Irgit, Reyhan Kamıs, Belgin Sever, Amaç Fatih Tuyun, Masami Otsuka, Mikako Fujita, Hasan Demirci, Halilibrahim Ciftci
Opublikowane w: Archiv der Pharmazie, Numer 358, 2025, ISSN 0365-6233
Wydawca: Wiley
DOI: 10.1002/ARDP.70005

A Review of FDA-Approved Anti-HIV-1 Drugs, Anti-Gag Compounds, and Potential Strategies for HIV-1 Eradication

Autorzy: Belgin Sever, Masami Otsuka, Mikako Fujita and Halilibrahim Ciftci
Opublikowane w: International Journal of Molecular Sciences, Numer 3659, 2024, ISSN 1422-0067
Wydawca: MDPI
DOI: 10.3390/ijms25073659

Structural Insights into the Dynamics of Water in SOD1 Catalysis and Drug Interactions

Autorzy: Ilkin Yapici, Arda Gorkem Tokur, Belgin Sever, Halilibrahim Ciftci, Ayse Nazli Basak, Hasan DeMirci
Opublikowane w: International Journal of Molecular Sciences, Numer 26, 2025, ISSN 1422-0067
Wydawca: MDPI AG
DOI: 10.3390/IJMS26094228