COMPUTER-AIDED EFFECTIVE FRACTURE RISK STRATIFICATION OF PATIENTS WITH VERTEBRAL METASTASES FOR PERSONALISED TREATMENT THROUGH ROBUST COMPUTATIONAL MODELS VALIDATED IN CLINICAL SETTINGS

Informacje na temat projektu

METASTRA

Identyfikator umowy o grant: 101080135

DOI

10.3030/101080135

Data podpisania przez KE 14 Marca 2023

Data rozpoczęcia 1 Lipca 2023

Data zakończenia 30 Czerwca 2028

Finansowanie w ramach

• Health

Koszt całkowity

€ 5 087 742,50

Wkład UE

€ 5 087 742,50

Koordynowany przez

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (4)

Report on the status of posting results at the end of the retrospective study Train-METASTRA

Report detailing the status of posting results at the end of the retrospective study (Train-METASTRA)

METASTRA Communication Toolkit

Communication material tailored to target-group, including material for policymakers, and material in layman's language

Midterm recruitment report for Train-METASTRA

It will be generated when 50% of the EHRs will be replicated through the transient loading zone from the primary hospital systems to the AlmaHealthDB servers. It will include an overview of the number of EHRs collected in each clinical site, indicating any problems in the process and measures eventually adopted to compensate for any delays.

Software documentation templates

The report will contain the templates for software documentation

Websites, patent fillings, videos etc. (1)

Public project website

Public website of the METASTRA project

Other (2)

Approval of ex vivo study by Ethics Committees of UNIBO and USFD

Ethics documentation for the ex vivo study (anatomical specimens from human donors) by Ethics Committees of UNIBO and USFD

Study initiation package for Validate-METASTRA study

Submission package, prior to enrolment of first subject, containing the final version of the study protocol as submitted to regulators, a registration number of the CT in a WHO or ICMJE-approved registry and approvals from ethics committees and national competent authorities

Publikacje

Peer reviewed articles (7)

Microstructure of the human metastatic vertebral body

Autorzy: Giulia Cavazzoni, Enrico Dall’Ara, Marco Palanca
Opublikowane w: Frontiers in Endocrinology, Numer 15, 2025, ISSN 1664-2392
Wydawca: Frontiers Media SA
DOI: 10.3389/fendo.2024.1508504

Variability of intervertebral joint stiffness between specimens and spine levels

Autorzy: Samuele L. Gould, Giorgio Davico, Christian Liebsch, Hans-Joachim Wilke, Luca Cristofolini, Marco Viceconti
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 12, 2024, ISSN 2296-4185
Wydawca: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1372088

Modelo paramétrico en 3D de elementos finitos para la simulación mecánica de vértebras con lesiones metastásicas

Autorzy: Jaime Muñoz Allué, José Manuel García Aznar, Mª Ángeles Pérez Ansón
Opublikowane w: Jornada de Jóvenes Investigadores del I3A, Numer 12, 2024, ISSN 2341-4790
Wydawca: Universidad de Zaragoza
DOI: 10.26754/jjii3a.202410652

Identification of a lumped-parameter model of the intervertebral joint from experimental data

Autorzy: Samuele L. Gould, Giorgio Davico, Marco Palanca, Marco Viceconti, Luca Cristofolini
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 12, 2024, ISSN 2296-4185
Wydawca: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1304334

Degeneration of the nucleus pulposus affects the internal volumetric strains and failure location of adjacent human metastatic vertebral bodies

Autorzy: Giulia Cavazzoni, Margherita Pasini, Christine L. Le Maitre, Enrico Dall'Ara, Marco Palanca
Opublikowane w: Acta Biomaterialia, 2025, ISSN 1742-7061
Wydawca: Elsevier BV
DOI: 10.1016/j.actbio.2025.01.018

METASTRA: COMPUTER-AIDED EFFECTIVE FRACTURE RISK STRATIFICATION OF PATIENTS WITH VERTEBRAL METASTASES FOR PERSONALIZED TREATMENT THROUGH ROBUST COMPUTATIONAL MODELS VALIDATED IN CLINICAL SETTINGS

Autorzy: L. Cristofolini, B. B. bròdano, E. Dall’Ara, R. Ferenc, S. J Ferguson, J. M. García-Aznar, A. Lazary, P. Vajkoczy, Jorrit-Jan Verlaan, L. Vidacs
Opublikowane w: Orthopaedic Proceedings, Numer 106-B, 2024, ISSN 1358-992X
Wydawca: British Editorial Society of Bone & Joint Surgery
DOI: 10.1302/1358-992X.2024.18.059

Experimental ex vivo characterization of the biomechanical effects of laminectomy and posterior fixation of the lumbo-sacral spine

Autorzy: Sara Montanari, Giovanni Barbanti Bròdano, Elena Serchi, Rita Stagni, Alessandro Gasbarrini, Alfredo Conti, Luca Cristofolini
Opublikowane w: Scientific Reports, Numer 14, 2024, ISSN 2045-2322
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s41598-024-80741-3