Comprehensive and personalized assessment of acute coronary syndrome by multiomic approach and artificial intelligence strategy

Informacje na temat projektu

CardioSCOPE

Identyfikator umowy o grant: 101086397

DOI

10.3030/101086397

Data podpisania przez KE 13 Października 2022

Data rozpoczęcia 1 Stycznia 2023

Data zakończenia 31 Grudnia 2026

Finansowanie w ramach

• Marie Skłodowska-Curie Actions (MSCA)

Koszt całkowity

Brak danych

Wkład UE

€ 1 518 000,00

Koordynowany przez

UNIVERSITA DEGLI STUDI DI MILANO
Italy

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Websites, patent fillings, videos etc. (1)

Plan for dissemination and exloitation including communication activities

Other (4)

SOP for analytical phase

set of optimized protocols related to the analytical phase

Study protocol

Set of optimized protocols related to patient recruitment and sample collection

SOP for ML/AI and bioinformatics

set of optimized protocols related to data integration and bioinformatics

SOP for pre-analytical phase

set of optimized protocols related to the preanalytical phase

Data Management Plan (1)

Data management plan

a report outlining the strategies and ethical requirements for collecting storing processing and sharing data generated during the project

Publikacje

Peer reviewed articles (22)

Editorial: Multiomic approaches in atherosclerosis

Autorzy: Sopić, Miron; Mitić, Tijana; Sluimer, Judith; Magni, Paolo; Devaux, Yvan
Opublikowane w: Vascular Pharmacology, 2025
Wydawca: ELSEVIER
DOI: 10.1016/J.VPH.2025.107501

Risk Factors and Immunoinflammatory Mechanisms Leading to Atherosclerosis: Focus on the Role of Oral Microbiota Dysbiosis

Autorzy: Riccardo Mattia Ricciardi; Alessia Cipollone; Damiano D’Ardes; Davide Di Giacomo; Pamela Pignatelli; Francesco Cipollone; Maria Cristina Curia; Paolo Magni; Marco Bucci
Opublikowane w: Microorganisms, 2023, ISSN 2076-2607
Wydawca: MDPI
DOI: 10.3390/MICROORGANISMS11061479

Costus afer Ker Gawl (Bush cane) extracts modulate glucose uptake, triglyceride accumulation and oxidative stress in human SW 872 liposarcoma and HepG2 hepatocarcinoma cells

Autorzy: Achille Parfait NWAKIBAN ATCHAN; Jules-Roger KUIATE; Gabriel AGBOR AGBOR; François Ferriere; Mario Dell’Agli; Paolo Magni; Armelle Deutou Tchamgoue
Opublikowane w: Crossref, 2025
Wydawca: RESEARCH SQUARE
DOI: 10.21203/RS.3.RS-5690853/V1

An integrated view of the pathophysiological crosstalk between adipose tissue, bone and cardiovascular system in men and women

Autorzy: Fationa Tolaj Klinaku; Laura Comi; Claudia Giglione; Paolo Magni
Opublikowane w: Journal of Endocrinological Investigation, 2024, ISSN 1720-8386
Wydawca: Springer
DOI: 10.1007/S40618-024-02516-X

Toward Precision Medicine in Atherosclerotic Cardiovascular Disease: Insights from Omics Data into Sex Differences

Autorzy: Munjas, Jelena; Vladimirov, Sandra; Ratković, Tamara; Comi, Laura; Giglione, Claudia; Tanasković, Ilija; Gojković, Tamara; Rakić, Branka; Davidović, Aleksandar; Vukmirović, Luka; Milanov, Marko; Cvijanović, Dane; Magni, Paolo; Sopić, Miron
Opublikowane w: Current Atherosclerosis Reports, 2025
Wydawca: SPRINGER NATURE
DOI: 10.1007/S11883-025-01380-1

Multiomics tools for improved atherosclerotic cardiovascular disease management

Autorzy: Sopić, Miron; Vilne, Baiba; Gerdts, Eva; Trindade, Fábio; Uchida, Shizuka; Khatib, Soliman; Wettinger, Stephanie Bezzina; Devaux, Yvan; Magni, Paolo
Opublikowane w: Trends in Molecular Medicine, 2023, ISSN 1471-4914
Wydawca: Elsevier BV
DOI: 10.1016/J.MOLMED.2023.09.004

LncRNAs as Regulators of Atherosclerotic Plaque Stability

Autorzy: Aleksa Petkovic; Sanja Erceg; Jelena Munjas; Ana Ninic; Sandra Vladimirov; Aleksandar Davidovic; Luka Vukmirovic; Marko Milanov; Dane Cvijanovic; Tijana Mitic; Miron Sopic
Opublikowane w: Cells, 2023, ISSN 2073-4409
Wydawca: MDPI
DOI: 10.3390/cells12141832

Current status and challenges of multi-omics research using animal models of atherosclerosis

Autorzy: Tijana Mitić; Adriana Georgescu; Nicoleta Alexandru-Moise; Michael J. Davies; Cecile Vindis; Susana Novella; Eva Gerdts; Georgios Kararigas; Stephanie Bezzina Wettinger; Melissa M. Formosa; Brenda R. Kwak; Filippo Molica; Nuria Amigo; Andrea Caporali; Fernando de la Cuesta; Ignacio Fernando Hall; Angeliki Chroni; Fabio Martelli; Johannes A. Schmid; Paolo Magni; Dimitris Kardassis
Opublikowane w: Journal of Molecular and Cellular Cardiology Plus, 2025
Wydawca: ELSEVIER
DOI: 10.1016/J.JMCCPL.2025.100476

Navigating the path of reproducibility in microRNA-based biomarker research with ring trials

Autorzy: Sopić, Miron; Devaux, Yvan; de Gonzalo-Calvo, David
Opublikowane w: Clinical Chemistry and Laboratory Medicine (CCLM), 2024
Wydawca: DE GRUYTER BRILL
DOI: 10.1515/CCLM-2024-0531

Additional file 1 of Web discussions on cardiovascular diseases: pre-COVID-19 evaluation and impact of the COVID-19 pandemic – Web listening analysis in the Italian population

Autorzy: Cecchini, Isabella; Biroli, Matteo; Massaroni, Katia; Folco, Emanuela; Montebelli, Maria Rita; Ciancamerla, Giuseppe; Giudice, Daniela; Pedretti, Roberto Franco Enrico; Magni, Paolo
Opublikowane w: 2024
Wydawca: FIGSHARE
DOI: 10.6084/M9.FIGSHARE.27928424.V1

Insulin-like Growth Factor 1, Growth Hormone, and Anti-Müllerian Hormone Receptors Are Differentially Expressed during GnRH Neuron Development

Autorzy: Alyssa J. J. Paganoni; Rossella Cannarella; Roberto Oleari; Federica Amoruso; Renata Antal; Marco Ruzza; Chiara Olivieri; Rosita A. Condorelli; Sandro La Vignera; Fationa Tolaj; Anna Cariboni; Aldo E. Calogero; Paolo Magni
Opublikowane w: International Journal of Molecular Sciences; Volume 24; Numer 17; Pages: 13073, 2023, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/IJMS241713073

Multiomics in atherosclerotic cardiovascular disease

Autorzy: Nordestgaard, Liv Tybjærg; Wolford, Brooke N.; de Gonzalo-Calvo, David; Sopić, Miron; Devaux, Yvan; Matic, Ljubica; Wettinger, Stephanie Bezzina; Schmid, Johannes A.; Amigó, Núria; Masana, Lluís; Catapano, Alberico L.; Kardassis, Dimitris; Magni, Paolo
Opublikowane w: Atherosclerosis, 2025
Wydawca: ELSEVIER
DOI: 10.1016/J.ATHEROSCLEROSIS.2025.120414

Nutraceutical alternatives to red yeast rice extract/monacolin K for moderate hypercholesterolaemia: Current evidence and knowledge gaps: Nutraceuticals and hypercholesterolaemia

Autorzy: Comi, Laura; Giglione, Claudia; Tolaj, Fationa; Parolini, Cinzia; Olivieri, Chiara; Ruzza, Marco; Tollemeto, Valentina; Zurlo, Maria; Pialorsi, Federico; Seneci, Antonio; Magni, Paolo
Opublikowane w: European Atherosclerosis Journal, 2023
Wydawca: European Atherosclerosis Journal
DOI: 10.56095/EAJ.V1I3.20

Single-cell RNA sequencing (scRNA-seq) and its insights into cellular heterogeneity in atherosclerosis

Autorzy: Yu, Baixue; Sopić, Miron; Sluimer, Judith C.
Opublikowane w: Vascular Pharmacology, 2025
Wydawca: ELSEVIER
DOI: 10.1016/J.VPH.2025.107499

Adherence to Mediterranean Diet: A Population-Based Longitudinal Cohort Study

Autorzy: Elisa Mattavelli; Elena Olmastroni; Manuela Casula; Liliana Grigore; Fabio Pellegatta; Andrea Baragetti; Paolo Magni; Alberico L. Catapano
Opublikowane w: Nutrients; Volume 15; Numer 8; Pages: 1844, 2023, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/NU15081844

Evaluation of Metabolic Dysfunction-Associated Fatty Liver Disease-Related Pathogenic Mechanisms in Human Steatotic Liver Cell-Based Model: Beneficial Effects of Prunus domestica L. subsp. syriaca Extract

Autorzy: Laura Comi; Claudia Giglione; Fationa Tolaj Klinaku; Lorenzo Da Dalt; Hammad Ullah; Maria Daglia; Paolo Magni
Opublikowane w: Nutrients, 2025
Wydawca: MDPI
DOI: 10.3390/NU17071249

British Journal of Pharmacology

Autorzy: Miron Sopić; Sandra Vladimirov; Jelena Munjas; Tijana Mitić; Ignacio Fernando Hall; Amela Jusic; Dusan Ruzic; Yvan Devaux
Opublikowane w: British Journal of Pharmacology, 2024, ISSN 0007-1188
Wydawca: British Pharmacological Society
DOI: 10.1111/BPH.16412

Valorizing Agro‐Food Waste for Nutraceutical Development: Sustainable Approaches for Managing Metabolic Dysfunction‐Associated Steatotic Liver Disease and Related Co‐Morbidities

Autorzy: Comi, Laura; Giglione, Claudia; Klinaku, Fationa Tolaj; Pialorsi, Federico; Tollemeto, Valentina; Zurlo, Maria; Seneci, Antonio; Magni, Paolo
Opublikowane w: Food Frontiers, 2024
Wydawca: WILEY
DOI: 10.1002/FFT2.535

Integration of epigenetic regulatory mechanisms in heart failure

Autorzy: Sopić, Miron; Robinson, Emma L.; Emanueli, Costanza; Srivastava, Prashant; Angione, Claudio; Gaetano, Carlo; Condorelli, Gianluigi; Martelli, Fabio; Pedrazzini, Thierry; Devaux, Yvan
Opublikowane w: Basic Research in Cardiology, 2023, ISSN 0300-8428
Wydawca: Springer Science and Business Media Deutschland GmbH
DOI: 10.1007/S00395-023-00986-3

The converging roles of microRNAs and lipid metabolism in atherosclerotic cardiovascular disease and cancer

Autorzy: Vladimirov, Sandra; Tomašević, Marija; Popov, Nemanja; Munjas, Jelena; de Gonzalo-Calvo, David; Sopić, Miron
Opublikowane w: Seminars in Cancer Biology, 2025
Wydawca: ELSEVIER
DOI: 10.1016/J.SEMCANCER.2025.06.005

BMC Public Health

Autorzy: Cecchini I.; Biroli M.; Massaroni K.; Folco E.; Montebelli M. R.; Ciancamerla G.; Giudice D.; Pedretti R. F. E.; Magni P.
Opublikowane w: BMC Public Health, 2024, ISSN 1471-2458
Wydawca: BMC
DOI: 10.1186/S12889-024-20615-5

Transcriptomic research in atherosclerosis: Unravelling plaque phenotype and overcoming methodological challenges

Autorzy: Sopić, Miron; Karaduzovic-Hadziabdic, Kanita; Kardassis, Dimitris; Maegdefessel, Lars; Martelli, Fabio; Meerson, Ari; Munjas, Jelena ; Niculescu, Loredan S.; Stoll, Monika; Magni, Paolo; Devaux, Yvan;
Opublikowane w: Journal of Molecular and Cellular Cardiology Plus, 2023, ISSN 2772-9761
Wydawca: ELSEVIER
DOI: 10.1016/J.JMCCPL.2023.100048