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ToWards Immunisations that Last: the Immunology and Gerontology of Helper T cells


Human blood T fr cells are indicators of ongoing humoral activity not fully licensed with suppressive function

Autorzy: Valter R. Fonseca, Ana Agua-Doce, Ana Raquel Maceiras, Wim Pierson, Filipa Ribeiro, Vasco C. Romão, Ana Rita Pires, Susana Lopes da Silva, João Eurico Fonseca, Ana E. Sousa, Michelle A. Linterman, Luis Graca
Opublikowane w: Science Immunology, 2/14, 2017, Page(s) eaan1487, ISSN 2470-9468
Wydawca: AAAs
DOI: 10.1126/sciimmunol.aan1487

Signals that drive T follicular helper cell formation

Autorzy: Louise M. C. Webb, Michelle A. Linterman
Opublikowane w: Immunology, 152/2, 2017, Page(s) 185-194, ISSN 0019-2805
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/imm.12778

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

Autorzy: Meryem Aloulou, Edward J. Carr, Mylène Gador, Alexandre Bignon, Roland S. Liblau, Nicolas Fazilleau, Michelle A. Linterman
Opublikowane w: Nature Communications, 7, 2016, Page(s) 10579, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms10579

The cellular composition of the human immune system is shaped by age and cohabitation

Autorzy: Edward J Carr, James Dooley, Josselyn E Garcia-Perez, Vasiliki Lagou, James C Lee, Carine Wouters, Isabelle Meyts, An Goris, Guy Boeckxstaens, Michelle A Linterman, Adrian Liston
Opublikowane w: Nature Immunology, 17/4, 2016, Page(s) 461-468, ISSN 1529-2908
Wydawca: Nature Publishing Group
DOI: 10.1038/ni.3371

Can follicular helper T cells be targeted to improve vaccine efficacy?

Autorzy: Michelle A. Linterman, Danika L. Hill
Opublikowane w: F1000Research, 2016, ISSN 2046-1402
Wydawca: F1000 Research Ltd.
DOI: 10.12688/f1000research.7388.1

Heterochronic faecal transplantation boosts gut germinal centres in aged mice

Autorzy: Marisa Stebegg, Alyssa Silva-Cayetano, Silvia Innocentin, Timothy P. Jenkins, Cinzia Cantacessi, Colin Gilbert, Michelle A. Linterman
Opublikowane w: Nature Communications, 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-10430-7

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes

Autorzy: Danika L. Hill, Wim Pierson, Daniel J. Bolland, Catherine Mkindi, Edward J. Carr, Jiong Wang, Sophie Houard, Steven W. Wingett, Regine Audran, Elizabeth F. Wallin, Said A. Jongo, Kassim Kamaka, Martin Zand, Francois Spertini, Claudia Daubenberger, Anne E. Corcoran, Michelle A. Linterman
Opublikowane w: The Journal of Experimental Medicine, 216/8, 2019, Page(s) 1857-1873, ISSN 0022-1007
Wydawca: Rockefeller University Press
DOI: 10.1084/jem.20190301

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5

Autorzy: Ine Vanderleyden, Sigrid C. Fra-Bido, Silvia Innocentin, Marisa Stebegg, Hanneke Okkenhaug, Nicola Evans-Bailey, Wim Pierson, Alice E. Denton, Michelle A. Linterman
Opublikowane w: Cell Reports, 30/3, 2020, Page(s) 611-619.e4, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2019.12.076

Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination

Autorzy: Marisa Stebegg, Alexandre Bignon, Danika Lea Hill, Alyssa Silva-Cayetano, Christel Krueger, Ine Vanderleyden, Silvia Innocentin, Louis Boon, Jiong Wang, Martin S Zand, James Dooley, Jonathan Clark, Adrian Liston, Edward Carr, Michelle A Linterman
Opublikowane w: eLife, 9, 2020, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.52473

Intrinsic defects in lymph node stromal cells underpin poor germinal center responses during aging

Autorzy: Alice E Denton, Alyssa Silva-Cayetano, James Dooley, Danika L Hill, Edward J Carr, Philippe A Robert, Michael Meyer-Hermann, Adrian Liston, Michelle A Linterman
Opublikowane w: 2020
Wydawca: bioRxiv preprint
DOI: 10.1101/2020.05.07.082255