AEGLE (Ancient Greek: Αἴγλη) – An analytics framework for integrated and personalized healthcare services in Europe

Informacje na temat projektu

AEGLE

Identyfikator umowy o grant: 644906

DOI

10.3030/644906

Projekt został zamknięty

Data podpisania przez KE 12 Grudnia 2014

Data rozpoczęcia 1 Marca 2015

Data zakończenia 31 Sierpnia 2018

Finansowanie w ramach

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)

Koszt całkowity

€ 6 079 642,50

Wkład UE

€ 5 230 698,75

Koordynowany przez

EXODUS ANONYMOS ETAIREIA PLIROFORIKIS
Greece

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Demonstrators, pilots, prototypes (3)

AEGLE third prototype

AEGLE's third integrated prototype

AEGLE Certification

Certification for the AEGLE product

AEGLE product

AEGLE final prototype (product)

Open Research Data Pilot (1)

AEGLE Best Practices

This deliverable will be the amalgamation of AEGLE project results combining technical, business and ethical aspects aiming to support other big-data efforts in the field of health.

Documents, reports (5)

Business and HTA framework

Business and HTA framework for AEGLE project

AEGLE final strategy, business evaluation and feasibility analysis

Report on AEGLE's final strategy, business evaluation and feasibility analysis

Market Research Report

Market and Research for the AEGLE Start-Up

AEGLE Legal Framework

Legal assessment for adressing the issues concerning the use of big-data in healthcare

Final system design

Final system design report

Websites, patent fillings, videos etc. (3)

Project's Stationary

AEGLEs stationary

Project’s Promotional material

AEGLE's promotional Material

Project's Website

AEGLEs official website

Other (1)

Final components for local, cloud-level BigData Analytics and Applications

Publikacje

Peer reviewed articles (22)

Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia

Autorzy: A. Vardi, A. Agathangelidis, E. Stalika, M. Karypidou, A. Siorenta, A. Anagnostopoulos, R. Rosenquist, A. Hadzidimitriou, P. Ghia, L.-A. Sutton, K. Stamatopoulos
Opublikowane w: Clinical Cancer Research, Numer 22/1, 2016, Strona(/y) 167-174, ISSN 1078-0432
Wydawca: American Association for Cancer Research
DOI: 10.1158/1078-0432.CCR-14-3017

An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors

Autorzy: V. Bikos, M. Karypidou, E. Stalika, P. Baliakas, A. Xochelli, L.-A. Sutton, G. Papadopoulos, A. Agathangelidis, E. Papadopoulou, Z. Davis, P. Algara, G. Kanellis, A. Traverse-Glehen, M. Mollejo, A. Anagnostopoulos, M. Ponzoni, D. Gonzalez, S. Pospisilova, E. Matutes, M. A. Piris, T. Papadaki, P. Ghia, R. Rosenquist, D. Oscier, N. Darzentas, D. Tzovaras, C. Belessi, A. Hadzidimitriou, K. Stamatopou
Opublikowane w: Clinical Cancer Research, Numer 22/8, 2016, Strona(/y) 2032-2040, ISSN 1078-0432
Wydawca: American Association for Cancer Research
DOI: 10.1158/1078-0432.CCR-15-1170

Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?

Autorzy: P. Baliakas, M. Mattsson, K. Stamatopoulos, R. Rosenquist
Opublikowane w: Journal of Internal Medicine, Numer 279/4, 2016, Strona(/y) 347-357, ISSN 0954-6820
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/joim.12455

A Customizable Framework for Application Implementation onto 3-D FPGAs

Autorzy: Kostas Siozios, Dimitrios Soudris
Opublikowane w: IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, 2016, Strona(/y) 1-1, ISSN 0278-0070
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TCAD.2016.2529421

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Autorzy: V. Ljungstrom, D. Cortese, E. Young, T. Pandzic, L. Mansouri, K. Plevova, S. Ntoufa, P. Baliakas, R. Clifford, L.-A. Sutton, S. J. Blakemore, N. Stavroyianni, A. Agathangelidis, D. Rossi, M. Hoglund, J. Kotaskova, G. Juliusson, C. Belessi, N. Chiorazzi, P. Panagiotidis, A. W. Langerak, K. E. Smedby, D. Oscier, G. Gaidano, A. Schuh, F. Davi, C. Pott, J. C. Strefford, L. Trentin, S. Pospisilova, P.
Opublikowane w: Blood, Numer 127/8, 2016, Strona(/y) 1007-1016, ISSN 0006-4971
Wydawca: American Society of Hematology
DOI: 10.1182/blood-2015-10-674572

A Systematic Methodology for Optimization of Applications Utilizing Concurrent Data Structures

Autorzy: Lazaros Papadopoulos, Ivan Walulya, Philippas Tsigas, Dimitris Soudris
Opublikowane w: IEEE Transactions on Computers, 2015, Strona(/y) 1-1, ISSN 0018-9340
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TC.2015.2479604

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Autorzy: S. Pospisilova, L.-A. Sutton, J. Malcikova, E. Tausch, D. Rossi, E. Montserrat, C. Moreno, K. Stamatopoulos, G. Gaidano, R. Rosenquist, P. Ghia
Opublikowane w: Haematologica, Numer 101/3, 2016, Strona(/y) 263-265, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2015.139246

A critique of the regulation of data science in healthcare research in the European Union

Autorzy: John M. M. Rumbold, Barbara K. Pierscionek
Opublikowane w: BMC Medical Ethics, Numer 18/1, 2017, ISSN 1472-6939
Wydawca: BioMed Central
DOI: 10.1186/s12910-017-0184-y

The Effect of the General Data Protection Regulation on Medical Research

Autorzy: John Mark Michael Rumbold, Barbara Pierscionek
Opublikowane w: Journal of Medical Internet Research, Numer 19/2, 2017, Strona(/y) e47, ISSN 1438-8871
Wydawca: Journal of medical Internet Research
DOI: 10.2196/jmir.7108

Reply to Why patients shouldn't “own” their medical records

Autorzy: John Rumbold; Barbara Pierscionek
Opublikowane w: Nature Biotechnology, Numer 34/6, 2016, Strona(/y) 586-587, ISSN 1087-0156
Wydawca: Nature Publishing Group
DOI: 10.1038/nbt.3615

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia

Autorzy: E Young, D Noerenberg, L Mansouri, V Ljungström, M Frick, L-A Sutton, S J Blakemore, J Galan-Sousa, K Plevova, P Baliakas, D Rossi, R Clifford, D Roos-Weil, V Navrkalova, B Dörken, C A Schmitt, K E Smedby, G Juliusson, B Giacopelli, J S Blachly, C Belessi, P Panagiotidis, N Chiorazzi, F Davi, A W Langerak, D Oscier, A Schuh, G Gaidano, P Ghia, W Xu, L Fan, O A Bernard, F Nguyen-Khac, L Rassenti,
Opublikowane w: Leukemia, Numer 31/7, 2016, Strona(/y) 1547-1554, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/leu.2016.359

Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors

Autorzy: L.-A. Sutton, E. Young, P. Baliakas, A. Hadzidimitriou, T. Moysiadis, K. Plevova, D. Rossi, J. Kminkova, E. Stalika, L. B. Pedersen, J. Malcikova, A. Agathangelidis, Z. Davis, L. Mansouri, L. Scarfo, M. Boudjoghra, A. Navarro, A. F. Muggen, X.-J. Yan, F. Nguyen-Khac, M. Larrayoz, P. Panagiotidis, N. Chiorazzi, C. U. Niemann, C. Belessi, E. Campo, J. C. Strefford, A. W. Langerak, D. Oscier, G. Gaid
Opublikowane w: Haematologica, Numer 101/8, 2016, Strona(/y) 959-967, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2016.141812

"ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres"

Autorzy: V. Navrkalova, E. Young, P. Baliakas, L. Radova, L.-A. Sutton, K. Plevova, L. Mansouri, V. Ljungstrom, S. Ntoufa, Z. Davis, G. Juliusson, K. E. Smedby, C. Belessi, P. Panagiotidis, T. Touloumenidou, F. Davi, A. W. Langerak, P. Ghia, J. C. Strefford, D. Oscier, J. Mayer, K. Stamatopoulos, S. Pospisilova, R. Rosenquist, M. Trbusek
Opublikowane w: Haematologica, Numer 101/9, 2016, Strona(/y) e369-e373, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2016.142968

Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference

Autorzy: P. Baliakas, A. Puiggros, A. Xochelli, L.-A. Sutton, F. Nguyen-Khac, A. Gardiner, K. Plevova, E. Minga, A. Hadzidimitriou, R. Walewska, H. McCarthy, M. Ortega, R. Collado, T. Gonzalez, I. Granada, E. Luno, J. Kota kova, T. Moysiadis, Z. Davis, N. Stavroyianni, A. Anagnostopoulos, J. C. Strefford, S. Pospisilova, F. Davi, A. Athanasiadou, R. Rosenquist, D. Oscier, B. Espinet, K. Stamatopoulos
Opublikowane w: Haematologica, Numer 101/7, 2016, Strona(/y) e299-e302, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2015.140202

Clusters of ineffective efforts during mechanical ventilation: impact on outcome

Autorzy: Katerina Vaporidi, Dimitris Babalis, Achilleas Chytas, Emmanuel Lilitsis, Eumorfia Kondili, Vasilis Amargianitakis, Ioanna Chouvarda, Nicos Maglaveras, Dimitris Georgopoulos
Opublikowane w: Intensive Care Medicine, Numer 43/2, 2017, Strona(/y) 184-191, ISSN 0342-4642
Wydawca: Springer Verlag
DOI: 10.1007/s00134-016-4593-z

Design-Efficient Approximate Multiplication Circuits Through Partial Product Perforation

Autorzy: Georgios Zervakis, Kostas Tsoumanis, Sotirios Xydis, Dimitrios Soudris, Kiamal Pekmestzi
Opublikowane w: IEEE Transactions on Very Large Scale Integration (VLSI) Systems, Numer 24/10, 2016, Strona(/y) 3105-3117, ISSN 1063-8210
Wydawca: Institute of Electrical and Electronics Engineers
DOI: 10.1109/TVLSI.2016.2535398

Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of “towards analysis” in chronic lymphocytic leukaemia

Autorzy: Ioannis Kavakiotis, Aliki Xochelli, Andreas Agathangelidis, Grigorios Tsoumakas, Nicos Maglaveras, Kostas Stamatopoulos, Anastasia Hadzidimitriou, Ioannis Vlahavas, Ioanna Chouvarda
Opublikowane w: BMC Bioinformatics, Numer 17/S5, 2016, ISSN 1471-2105
Wydawca: BioMed Central
DOI: 10.1186/s12859-016-1044-3

Antigen receptor stereotypy in chronic lymphocytic leukemia

Autorzy: K Stamatopoulos, A Agathangelidis, R Rosenquist, P Ghia
Opublikowane w: Leukemia, Numer 31/2, 2016, Strona(/y) 282-291, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/leu.2016.322

SoftRM

Autorzy: Vasileios Tsoutsouras, Dimosthenis Masouros, Sotirios Xydis, Dimitrios Soudris
Opublikowane w: ACM Transactions on Embedded Computing Systems, Numer 16/5s, 2017, Strona(/y) 1-19, ISSN 1539-9087
Wydawca: Association for Computing Machinary, Inc.
DOI: 10.1145/3126562

Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification

Autorzy: Lesley-Ann Sutton, Anastasia Hadzidimitriou, Panagiotis Baliakas, Andreas Agathangelidis, Anton W. Langerak, Stephan Stilgenbauer, Sarka Pospisilova, Zadie Davis, Francesco Forconi, Frederic Davi, Paolo Ghia, Richard Rosenquist, Kostas Stamatopoulos
Opublikowane w: Haematologica, Numer 102/6, 2017, Strona(/y) 968-971, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2017.165605

NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions

Autorzy: Larry Mansouri, Nikos Papakonstantinou, Stavroula Ntoufa, Kostas Stamatopoulos, Richard Rosenquist
Opublikowane w: Seminars in Cancer Biology, Numer 39, 2016, Strona(/y) 40-48, ISSN 1044-579X
Wydawca: Academic Press
DOI: 10.1016/j.semcancer.2016.07.005

Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond

Autorzy: R. Rosenquist, A. Rosenwald, M.-Q. Du, G. Gaidano, P. Groenen, A. Wotherspoon, P. Ghia, P. Gaulard, E. Campo, K. Stamatopoulos
Opublikowane w: Haematologica, Numer 101/9, 2016, Strona(/y) 1002-1009, ISSN 0390-6078
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2015.134510

Book chapters (1)

Reconfigurable Computing for Analytics Acceleration of Big Bio-Data: The AEGLE Approach

Autorzy: Andreas Raptopoulos, Sotirios Xydis, Dimitrios Soudris
Opublikowane w: Applied Reconfigurable Computing, 2015, Strona(/y) 531-541, ISBN 978-3-319-16214-0
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-319-16214-0_49

Non-peer reviewed articles (2)

Machine Learning and Data Mining Methods in Diabetes Research

Autorzy: Ioannis Kavakiotis, Olga Tsave, Athanasios Salifoglou, Nicos Maglaveras, Ioannis Vlahavas, Ioanna Chouvarda
Opublikowane w: Computational and Structural Biotechnology Journal, Numer 15, 2017, Strona(/y) 104-116, ISSN 2001-0370
Wydawca: Computational and Structural Biotechnology Journal
DOI: 10.1016/j.csbj.2016.12.005

Does your electronic butler owe you a duty of confidentiality?

Autorzy: John Rumbold, Barbara Pierscionek
Opublikowane w: Computer Law Review International, Numer 18/2, 2017, ISSN 2194-4164
Wydawca: Computer Law Review International
DOI: 10.9785/cri-2017-0206

Conference proceedings (7)

Performance-power exploration of software-defined big data analytics: The AEGLE cloud backend

Autorzy: Georgios Zervakis, Sotirios Xydis, Dimitrios Soudris
Opublikowane w: 2016 International Conference on Embedded Computer Systems: Architectures, Modeling and Simulation (SAMOS), 2016, Strona(/y) 312-319, ISBN 978-1-5090-3076-7
Wydawca: IEEE
DOI: 10.1109/SAMOS.2016.7818364

Distributed QoS management for internet of things under resource constraints

Autorzy: Farzad Samie, Vasileios Tsoutsouras, Sotirios Xydis, Lars Bauer, Dimitrios Soudris, Jörg Henkel
Opublikowane w: Proceedings of the Eleventh IEEE/ACM/IFIP International Conference on Hardware/Software Codesign and System Synthesis - CODES '16, 2016, Strona(/y) 1-10, ISBN 9781-450344838
Wydawca: ACM Press
DOI: 10.1145/2968456.2974005

Computation offloading and resource allocation for low-power IoT edge devices

Autorzy: Farzad Samie, Vasileios Tsoutsouras, Lars Bauer, Sotirios Xydis, Dimitrios Soudris, Jorg Henkel
Opublikowane w: 2016 IEEE 3rd World Forum on Internet of Things (WF-IoT), 2016, Strona(/y) 7-12, ISBN 978-1-5090-4130-5
Wydawca: IEEE
DOI: 10.1109/WF-IoT.2016.7845499

Dataflow Acceleration of scikit-learn Gaussian Process Regression

Autorzy: Michail Doukas, Sotirios Xydis, Dimitrios Soudris
Opublikowane w: Proceedings of the 8th Workshop and 6th Workshop on Parallel Programming and Run-Time Management Techniques for Many-core Architectures and Design Tools and Architectures for Multicore Embedded Computing Platforms - PARMA-DITAM '17, 2017, Strona(/y) 1-6, ISBN 9781-450348775
Wydawca: ACM Press
DOI: 10.1145/3029580.3029587

Novel Methods for Correcting Next Generation Sequencing Errors in the β Chain of T Cell Receptors

Autorzy: Chrysi Panopoulou, Christos Maramis, Nicos Maglaveras, Ioanna Chouvarda
Opublikowane w: 2016, Strona(/y) 529-534
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-319-32703-7_103

Ineffective Efforts in ICU Assisted Ventilation: Feature Extraction and Analysis Platform

Autorzy: Achilleas Chytas, Katerina Vaporidi, Dimitris Babalis, Dimitris Georgopoulos, Nicos Maglaveras, Ioanna Chouvarda
Opublikowane w: 2016, Strona(/y) 642-650
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-319-44944-9_57

AEGLE's Cloud Infrastructure for Resource Monitoring and Containerized Accelerated Analytics

Autorzy: Konstantina Koliogeorgi, Dimosthenis Masouros, Georgios Zervakis, Sotirios Xydis, Tobias Becker, Georgi Gaydadjiev, Dimitrios Soudris
Opublikowane w: 2017 IEEE Computer Society Annual Symposium on VLSI (ISVLSI), 2017, Strona(/y) 362-367, ISBN 978-1-5090-6762-6
Wydawca: IEEE
DOI: 10.1109/ISVLSI.2017.70