Probing safety of nano-objects by defining immune responses of environmental organisms

Rezultaty

NP interaction with innate immune cells/receptors

Report encompassing the joint results of individual projects 1, 2, 3, 5, 10, 11.

Industrial outreach

Reports on industrial outreach activities Multiple delivery dates Months 18 30 42

Local training

Reports on local training activities. Multiple delivery dates: Months 18, 30, 42.

Secondments

Reports on secondments Multiple delivery dates Months 25 43

Setting up immuno-risk predictive cell-based in vitro assays

Report encompassing the joint results of individual projects 1, 2, 3, 9, 11.

Virtual outreach

Reports on virtual outreach activities. Multiple delivery dates: Months 18, 30, 42.

Defining biomarkers of environmental immuno-risk

Report encompassing the joint results of individual projects 1-11.

Academic outreach

Reports on academic outreach activities. Multiple delivery dates: Months 18, 30, 42.

Dissemination

Reports on dissemination activities. Multiple delivery dates: Months 12, 24, 36, 48.

Individual CDP

Preparation of individual Career Development Plans.

Modulation of immune-pathogen interaction by NP

Report encompassing the joint results of individual projects 1, 2, 3, 5, 6, 7, 8, 10.

PhD thesis

PhD thesis for all ESR.

SSC activities

Organisation of Short Scientific Courses. Multiple delivery dates: Months 10, 22, 34.

Recruitment

Report on the recruitment process, including publication of call, CV evaluation, interview outcome, final decision on the fellows.

SCT activities

Organisation of Short Courses of Transferrable training (SCT). Multiple delivery dates: Months 16, 28, 40.

Website

Development of the project website.

Scientific meetings

Scientific meetings organisation. Multiple delivery dates: Months 10, 22, 34.

Final Workshop

Final Workshop organisation.

Publikacje

Probing safety of nanoparticles by outlining sea urchin sensing and signaling cascades

Autorzy: Andi Alijagic, Annalisa Pinsino
Opublikowane w: Ecotoxicology and Environmental Safety, Numer 144, 2017, Strona(/y) 416-421, ISSN 0147-6513
Wydawca: Academic Press
DOI: 10.1016/j.ecoenv.2017.06.060

Formation of the Protein Corona: The Interface between Nanoparticles and the Immune System

Autorzy: Francesco Barbero, Lorenzo Russo, Michele Vitali, Jordi Piella, Ignacio Salvo, Mireya L. Borrajo, Marti Busquets-Fité, Rita Grandori, Neus G. Bastús, Eudald Casals, Victor Puntes
Opublikowane w: Seminars in Immunology, Numer 34, 2017, Strona(/y) 52-60, ISSN 1044-5323
Wydawca: Academic Press
DOI: 10.1016/j.smim.2017.10.001

Sea Urchin Extracellular Proteins Design a Complex Protein Corona on Titanium Dioxide Nanoparticle Surface Influencing Immune Cell Behavior

Autorzy: Andi Alijagic, Oldřich Benada, Olga Kofroňová, Diego Cigna, Annalisa Pinsino
Opublikowane w: Frontiers in Immunology, Numer 10, 2019, ISSN 1664-3224
Wydawca: -
DOI: 10.3389/fimmu.2019.02261

Effects of nanosilver on Mytilus galloprovincialis hemocytes and early embryo development

Autorzy: M. Auguste, C. Ciacci, T. Balbi, A. Brunelli, V. Caratto, A. Marcomini, R. Cuppini, L. Canesi
Opublikowane w: Aquatic Toxicology, Numer 203, 2018, Strona(/y) 107-116, ISSN 0166-445X
Wydawca: Elsevier BV
DOI: 10.1016/j.aquatox.2018.08.005

In vivo immunomodulatory and antioxidant properties of nanoceria (nCeO2) in the marine mussel Mytilus galloprovincialis

Autorzy: M. Auguste, T. Balbi, M. Montagna, R. Fabbri, M. Sendra, J. Blasco, L. Canesi
Opublikowane w: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, Numer 219, 2019, Strona(/y) 95-102, ISSN 1532-0456
Wydawca: Elsevier BV
DOI: 10.1016/j.cbpc.2019.02.006

Exposure to TiO2 nanoparticles induces shifts in the microbiota composition of Mytilus galloprovincialis hemolymph

Autorzy: Manon Auguste, Aide Lasa, Alberto Pallavicini, Stefano Gualdi, Luigi Vezzulli, Laura Canesi
Opublikowane w: Science of The Total Environment, Numer 670, 2019, Strona(/y) 129-137, ISSN 0048-9697
Wydawca: Elsevier BV
DOI: 10.1016/j.scitotenv.2019.03.133

Interaction of engineered nanomaterials with the immune system: Health-related safety and possible benefits

Autorzy: Diana Boraschi, Benjamin J. Swartzwelter, Paola Italiani
Opublikowane w: Current Opinion in Toxicology, Numer 10, 2018, Strona(/y) 74-83, ISSN 2468-2020
Wydawca: -
DOI: 10.1016/j.cotox.2018.02.002

IL-1β induces expression of costimulatory molecules and cytokines but not immune feedback regulators in dendritic cells

Autorzy: Sara Michelini, Muamera Sarajlic, Albert Duschl, Jutta Horejs-Hoeck
Opublikowane w: Human Immunology, Numer 79/8, 2018, Strona(/y) 610-615, ISSN 0198-8859
Wydawca: Elsevier BV
DOI: 10.1016/j.humimm.2018.06.002

Sea urchin Paracentrotus lividus immune cells in culture: formulation of the appropriate harvesting and culture media and maintenance conditions

Autorzy: Annalisa Pinsino, Andi Alijagic
Opublikowane w: Biology Open, Numer 8/3, 2019, Strona(/y) bio039289, ISSN 2046-6390
Wydawca: -
DOI: 10.1242/bio.039289

First person – Annalisa Pinsino and Andi Alijagic

Autorzy: A. Pinsino, and A. Alijagic
Opublikowane w: Biology Open, Numer 8/3, 2019, Strona(/y) bio042242, ISSN 2046-6390
Wydawca: -
DOI: 10.1242/bio.042242

Developmental and Immune Role of a Novel Multiple Cysteine Cluster TLR From Eisenia andrei Earthworms

Autorzy: Petra Prochazkova, Radka Roubalova, Frantisek Skanta, Jiri Dvorak, Natividad Isabel Navarro Pacheco, Miroslav Kolarik, Martin Bilej
Opublikowane w: Frontiers in Immunology, Numer 10, 2019, ISSN 1664-3224
Wydawca: -
DOI: 10.3389/fimmu.2019.01277

Titanium dioxide nanoparticles temporarily influence the sea urchin immunological state suppressing inflammatory-relate gene transcription and boosting antioxidant metabolic activity

Autorzy: Andi Alijagic, Daniela Gaglio, Elisabetta Napodano, Roberta Russo, Caterina Costa, Oldřich Benada, Olga Kofroňová, Annalisa Pinsino
Opublikowane w: Journal of Hazardous Materials, Numer 384, 2020, Strona(/y) 121389, ISSN 0304-3894
Wydawca: Elsevier BV
DOI: 10.1016/j.jhazmat.2019.121389

Pattern recognition receptors in annelids

Autorzy: P. Prochazkova, R. Roubalova, J. Dvorak, N.I. Navarro Pacheco, M. Bilej
Opublikowane w: Developmental & Comparative Immunology, Numer 102, 2020, Strona(/y) 103493, ISSN 0145-305X
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.dci.2019.103493

Shift in Immune Parameters After Repeated Exposure to Nanoplastics in the Marine Bivalve Mytilus

Autorzy: Manon Auguste, Teresa Balbi, Caterina Ciacci, Barbara Canonico, Stefano Papa, Alessio Borello, Luigi Vezzulli, Laura Canesi
Opublikowane w: Frontiers in Immunology, Numer 11, 2020, Strona(/y) 426, ISSN 1664-3224
Wydawca: -
DOI: 10.3389/fimmu.2020.00426

Dynamic Equilibrium in the Cetyltrimethylammonium Bromide–Au Nanoparticle Bilayer, and the Consequent Impact on the Formation of the Nanoparticle Protein Corona

Autorzy: Francesco Barbero, Oscar H. Moriones, Neus G. Bastús, Victor Puntes
Opublikowane w: Bioconjugate Chemistry, Numer 30/11, 2019, Strona(/y) 2917-2930, ISSN 1043-1802
Wydawca: American Chemical Society
DOI: 10.1021/acs.bioconjchem.9b00624

Surface Exposure of PEG and Amines on Biodegradable Nanoparticles as a Strategy to Tune Their Interaction with Protein-Rich Biological Media

Autorzy: Claudia Conte, Giovanni Dal Poggetto, Benjamin J. Swartzwelter, Diletta Esposito, Francesca Ungaro, Paola Laurienzo, Diana Boraschi, Fabiana Quaglia
Opublikowane w: Nanomaterials, Numer 9/10, 2019, Strona(/y) 1354, ISSN 2079-4991
Wydawca: -
DOI: 10.3390/nano9101354

Addressing Nanomaterial Immunosafety by Evaluating Innate Immunity across Living Species

Autorzy: Diana Boraschi, Andi Alijagic, Manon Auguste, Francesco Barbero, Eleonora Ferrari, Szabolcs Hernadi, Craig Mayall, Sara Michelini, Natividad I. Navarro Pacheco, Alessandra Prinelli, Elmer Swart, Benjamin J. Swartzwelter, Neus G. Bastús, Laura Canesi, Damjana Drobne, Albert Duschl, Marie‐Ann Ewart, Jutta Horejs‐Hoeck, Paola Italiani, Birgit Kemmerling, Peter Kille, Petra Prochazkova, Victor F.
Opublikowane w: Small, Numer 16/21, 2020, Strona(/y) 2000598, ISSN 1613-6810
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202000598

Mechanisms of particles in sensitization, effector function and therapy of allergic disease.

Autorzy: A.I. Joubert, M. Geppert, L. Johnson, R. Mills-Goodlet, S. Michelini, E. Korotchenko, A. Duschl, R. Weiss, J. Horejs-Höck and M. Himly
Opublikowane w: Front. Immunol, Numer 11, 2020, Strona(/y) 1334
Wydawca: -
DOI: 10.3389/fimmu.2020.01334

Gold Nanoparticles Modulate BCG-Induced Innate Immune Memory in Human Monocytes by Shifting the Memory Response towards Tolerance

Autorzy: Benjamin J. Swartzwelter, Francesco Barbero, Alessandro Verde, Maria Mangini, Marinella Pirozzi, Anna Chiara De Luca, Victor F. Puntes, Luciana C. C. Leite, Paola Italiani, Diana Boraschi
Opublikowane w: Cells, Numer 9/2, 2020, Strona(/y) 284, ISSN 2073-4409
Wydawca: -
DOI: 10.3390/cells9020284

The Effects of in Vivo Exposure to Copper Oxide Nanoparticles on the Gut Microbiome, Host Immunity and Susceptibility to a Bacterial Infection in Earthworms

Autorzy: Elmer Swart, Jiri Dvorak, Szabolcs Hernádi, Tim Goodall, Peter Kille, David Spurgeon, Claus Svendsen and Petra Prochazkova
Opublikowane w: Nanomaterials, Numer 10, 2020, Strona(/y) 1337
Wydawca: -
DOI: 10.3390/nano10071337

Annelida: Environmental Interactions and Ecotoxicity in Relation to the Earthworm Immune System

Autorzy: Radka Roubalová, Barbara Płytycz, Petra Procházková, Natividad Isabel Navarro Pacheco, Martin Bilej
Opublikowane w: Advances in Comparative Immunology, 2018, Strona(/y) 933-951, ISBN 978-3-319-76767-3
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-319-76768-0_27

Rezultaty

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