Strategies towards Excellence in Immuno-Oncology

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Report on overall promotional activities I

Report will summarize the Promotional activities related to the project.

Report from the Steering Group Meeting I

Report will be considered as milestone, since it will summarize the project activities, progress and financial resources exploitation.

Report on know-how transfer through twinning visits - M36

Report on transfer of know-how and best practices to MUW as a result of twinning visits in collaborating institutions; will include the analysis of added value for potential increase of research capacity / quality of MUW and the analysis of STREAM funds exploitation; will be discussed during the annual Steering Group meetings.

"Report on organization of theoretical workshop - ""Adoptive immunotherapy for cancer"""

Report on organized workshop will include an agenda, a list of participants, presentations and conclusions. Each of the reports will be complemented by an evaluation on whether the concerned activities contribute to the Research Potential increase of the applicants and the necessary measures to be taken in order to preserve the sustainability of the implemented actions or benefits. Report will also include the summary of STREAM financial resources exploitation.

Report on know-how knowledge dissemination at MUW - M12

Report on sharing and dissemination of know-how knowledge, executed by weekly seminars at the Department of Immunology at MUW.

Report on participation in international research/innovation conferences - M36

Report on the attendance of European and world-wide conferences, symposia and meetings will be complemented by an evaluation on whether the concerned activities contribute to the Research Potential increase of the applicants and the necessary measures to be taken in order to preserve the sustainability of the implemented actions or benefits.

Specifications of training material used for the twinning visits

Deliverable D37 will include the list of training materials to be used to deliver high-quality training during the twinning visits.

Report on management activities III

Report will summarize the yearly Management activities.

Report from the Steering Group Meeting III

Report will be considered as milestone, since it will summarize the project activities, progress and financial resources exploitation.

Report on publications, patents and funding support resulting from twinning visits

Report on publications, patents and funding support, resulting from twinning visits.

Report from the Steering Group Meeting II

Report will be considered as milestone, since it will summarize the project activities, progress and financial resources exploitation.

Report on know-how transfer through twinning visits - M24

Report on overall promotional activities III

Report will summarize the Promotional activities related to the project.

Report on knowledge dissemination - M18

Report on dissemination of knowledge acquired during conferences, symposia and meetings.

Report on promotional activities undertaken during hands-on workshop

Report on the promotional activities undertaken before and during the workshop.

"Report on organization of international summer-school - ""Immuno-Oncology"""

Report on organized summer-school will include an agenda, a list of participants, presentations and conclusions. Each of the reports will be complemented by an evaluation on whether the concerned activities contribute to the Research Potential increase of the applicants and the necessary measures to be taken in order to preserve the sustainability of the implemented actions or benefits. Report will also include the summary of STREAM financial resources exploitation.

Report on participation in international research/innovation conferences - M18

Report on know-how transfer through twinning visits - M12

Report on promotional activities undertaken during theoretical workshop

Report on the promotional activities undertaken before and during the workshop.

Report on prior publications of the coordinator

A one-page statement that the information about prior publications of the coordinator has been provided.

Report on overall promotional activities II

Report will summarize the Promotional activities related to the project.

Report on know-how knowledge dissemination at MUW - M36

Report on sharing and dissemination of know-how knowledge, executed by weekly seminars at the Department of Immunology at MUW.

Report on management activities II

Report will summarize the yearly Management activities.

Report on management activities I

Report will summarize the yearly Management activities.

Report on knowledge dissemination - M36

Report on dissemination of knowledge acquired during conferences, symposia and meetings.

Report on promotional activities undertaken during summer-school

Report on the promotional activities undertaken before and during the summer-school.

Report on STREAM webpage launching

Report on the STREAM webpage launching is considered a Milestone in project implementation since it will be the basis for communication and promotion of the project.

"Report on organization of hands-on workshop - ""Application of flow cytometry methods in Immuno-Oncology"""

Report on know-how knowledge dissemination at MUW - M24

Report on sharing and dissemination of know-how knowledge, executed by weekly seminars at the Department of Immunology at MUW.

Publikacje

HDAC6 inhibition augments the efficacy of anti-CD20 monoclonal antibodies by up-regulating CD20 level in malignant B-cells

Autorzy: Bobrowicz, M.; Dwojak, M.; Bojarczuk, K.; et al.
Opublikowane w: HAEMATOLOGICA, Numer 99, Supplement: 1, 2014, Strona(/y) 437, Abstract: P1143
Wydawca: European-Hematology-Association

Protein disulphide inhibitors induce differentiation of human acute myeloid leukemia cells

Autorzy: Chlebowska, J.; Firczuk, M.; Furs, K.; et al.
Opublikowane w: HAEMATOLOGICA, Numer 99, Supplement: 1, 2014, Strona(/y) 558, Abstract: PB1430
Wydawca: European-Hematology-Association

SRC inhibitors downregulate CD20 and modulate the activity of the CD20 promoter

Autorzy: Winiarska, M.; Bojarczuk, K.; Pyrzynska, B.; et al
Opublikowane w: HAEMATOLOGICA, Numer 99, Supplement: 1, 2014, Strona(/y) 45, Abstract: P211
Wydawca: European-Hematology-Association

A novel pathway regulating CD20 level influence of the inhibition of HDAC6 on the efficacy of anti-CD20 antibodies

Autorzy: Bobrowicz, M.; Dwojak, M.; Bojarczuk, K.; et al.
Opublikowane w: FEBS JOURNAL, Numer 281, Special Numer: SI, Supplement: 1, 2014, Strona(/y) 239-240, Abstract: SUN-509
Wydawca: FEBS; EMBO

Thiol-Reactive Peptidomimetic SK053 Targets Dimeric Peroxiredoxins in Human Lymphoma Cell Lines. Oral presentation.

Autorzy: Firczuk, M; Trzeciecka, A; Klosowski, S; et al.
Opublikowane w: Journal of International Society of Antioxidants in Health & Nutrition, Numer 1/1, 2015, Strona(/y) 43
Wydawca: International Society of Antioxidants

Peroxiredoxins-1 and 2 Affect Proliferation and Survival of Lymphoma Cells

Autorzy: Firczuk, Malgorzata; Trzeciecka, Anna; Bajor, Malgorzata; et al.
Opublikowane w: BLOOD, Numer 124/21, 2014
Wydawca: American-Society-of-Hematology

HDAC Inhibitors As Potential New Agents Improving the Efficacy of Monoclonal Antibodies

Autorzy: Bobrowicz, Malgorzata; Dwojak, Michal; Malenda, Agata; et al.
Opublikowane w: BLOOD, Numer 124/21, 2014
Wydawca: American-Society-of-Hematology

Influence of Btk Inhibitors on Antitumor Activity of Natural Killer Cells

Autorzy: Siernicka, Marta; Bojarczuk, Kamil; Bobrowicz, Malgorzata; et al.
Opublikowane w: BLOOD, Numer 124/21, 2014
Wydawca: American-Society-of-Hematology

FoxO1 transcription factor mediates toxicity of SYK inhibition in DLBCL

Autorzy: Kiliszek, P.; Szydlowski, M.; Sewastianik, T.; Bialopiotrowicz, E.; Jablonska, E.; Polak, A.; Prusisz, W.; Markowicz, S.; Nowak, E.; Grygorowicz, MA.; Bojarczuk, K.; Winiarska, M.; Golab, J.; Juszczynski, P.
Opublikowane w: HAEMATOLOGICA, Numer 99, Supplement: 1, 2014, Strona(/y) 137, Abstract: P430
Wydawca: European-Hematology-Association

SK053 An Inhibitor of Enzymes Involved In Allosteric Disulfide Bonds Formation Induces Differentiation of Human AML Cells

Autorzy: Chlebowska, Justyna; Firczuk, Malgorzata; Furs, Karolina; et al.
Opublikowane w: BLOOD, Numer 122/21, 2013, Strona(/y) Abstract: 4215
Wydawca: American-Society-of-Hematology

Inhibitors of SRC family and AKT regulate the activity of CD20 promoter

Autorzy: Pyrzynska B., Bojarczuk K., Winiarska M. Bil J. Miazek N. Zapala P., Bobrowicz M., Dwojak M., Siernicka M., Golab J.
Opublikowane w: BLOOD, Numer 122/21, 2013, Strona(/y) Abstract: 1838
Wydawca: American-Society-of-Hematology

Abstract 3919: Targeting urease to human VEGFR2 elicits antitumor activity in triple-negative breast cancer models

Autorzy: Angelika Muchowicz, Anna Bujak, Beata Pyrzynska, Justyna Karolczak, Abdessamad Zerrouqi, Magdalena Ozga, Lukasz Szewczyk, Baomin Tian, Wah Wong, Marni Uger, Katarzyna Poplawska, Dorota Gierej, Pawel Wisniewski, Heman Chao, Magdalena Winiarska, Radoslaw Zagozdzon
Opublikowane w: Cancer Research, Numer 78, Suppl 13, 2018, Strona(/y) 3919-3919
Wydawca: American Association for Cancer Research

Ovarian cancer cells release arginase-1-containing exosomes to suppress antitumor immune response

Autorzy: Malgorzata Czystowska, Marta Szajnik, Kavita Ramji, Slawomir Gruca, Artur Stefanowicz, Jakub Golab, Dominika Nowis
Opublikowane w: Cancer Research, Numer 77, Suppl 13, 2017, Strona(/y) 3975-3975
Wydawca: American Association for Cancer Research

FOXO1 determines non-Hodgkin lymphomas response to anti-CD20-based therapy

Autorzy: Abdessamad Zerrouqi, Beata Pyrzynska, Michal Dwoyak, giulia Morlino, Piotr Zapala, Nina Miazek, Jakub Golab, Magdalena Winiarska
Opublikowane w: Cancer Research, Numer 78/10, Suppl, 2018, Strona(/y) B51-B51
Wydawca: American Association for Cancer Research

Dasatinib Effect on NK Cells and Anti-Tumor Immunity

Autorzy: Mieszko Lachota, Marta Siernicka, Zofia Pilch, Agnieszka Graczyk-Jarzynka and Magdalena Winiarska
Opublikowane w: Blood, Numer 132 (Suppl 1), 2018, Strona(/y) 3004
Wydawca: ASH

SHP1 Deficiency Is Responsible for the Constitutive Activation of the BCR Pathway in GCB DLBCL

Autorzy: Binu K Sasi, Sven Turkalj, Hilal Kalkan, Fabiola Porro, Engin Bojnik, Beata Pyrzynska, Abdessamad Zerrouqi, Malgorzata Bobrowicz, Magdalena Winiarska, Valdemar Priebe, Francesco Bertoni, Larry Mansouri, Richard Rosenquist and Dimitar G Efremov
Opublikowane w: Blood, Numer 132 (Suppl 1), 2018, Strona(/y) 2860
Wydawca: ASH

Lysosomal Disruption Augments Obinutuzumab-Induced Direct Cell Death

Autorzy: Antoni Domagala, Malgorzata Bobrowicz, Joanna Stachura, Marta Siernicka, Piotr Mrowka, Michal Dwojak, Beata Pyrzynska, Malgorzata Firczuk and Magdalena Winiarska
Opublikowane w: Blood, Numer 128/22, 2016, Strona(/y) 2766
Wydawca: ASH

HDAC6 Inhibition Increases Translation of CD20 mRNA and Potentiates the Efficacy of Anti-CD20 Immunotherapy

Autorzy: Malgorzata Bobrowicz, Joanna Stachura, Michal Dwojak, Antoni Domagala, Beata Pyrzynska, Elise Berthel, Nicole Dalla Venezia, Marta Siernicka, Malgorzata Firczuk and Magdalena Winiarska
Opublikowane w: Blood, Numer 128/22, 2016, Strona(/y) 1586
Wydawca: ASH

NK cells cytotoxicity is affected by various BTK inhibitors

Autorzy: Siernicka, M.; Bojarczuk, K.; Bobrowicz, M.; et al.
Opublikowane w: HAEMATOLOGICA, 2015, Strona(/y) 549-550, Abstract: E1372
Wydawca: European-Hematology-Association

Ofatumumab overcomes CD59-dependent resistance to complement-dependent cytotoxicity in human B-cell lymphoma model

Autorzy: Dwojak, M.; Bobrowicz, M.; Siernicka, M.; et al.
Opublikowane w: HAEMATOLOGICA, 2015, Strona(/y) 552-552, Abstract: E1379
Wydawca: European-Hematology-Association

SRC inhibitors downregulate CD20 and modulate the activity of the CD20 promoter

Autorzy: Winiarska, M.; Bojarczuk, K.; Pyrzynska, B.; et al
Opublikowane w: HAEMATOLOGICA, 2014, Strona(/y) 45, Abstract: P211
Wydawca: European-Hematology-Association

MEK1 inhibitor selumetinib sensitizes B-cell Acute Lymphoblastic Leukemia (B-ALL) cells to dexamethasone by modulating autophagy

Autorzy: Polak, A.; Kiliszek, P.; Sewastianik, T.; Szydlowski, M.; Jablonska, E.; Prusisz, W.; Bialopiotrowicz, E.; Markowicz, S.; Nowak, E.; Grygorowicz, M.; Nowis, D.; Bojarczuk, K.; Golab, J.; Juszczynski, P.
Opublikowane w: HAEMATOLOGICA, 2014, Strona(/y) 272, Abstract: P751
Wydawca: European-Hematology-Association

SK053-an allosteric protein disulphide isomerase inhibitor induces differentiation of human acute myeloid leukemia cells

Autorzy: Golab, J.; Chlebowska, J.; Firczuk, M.; et al.
Opublikowane w: HAEMATOLOGICA, 2014, Strona(/y) 296, Abstract: P809
Wydawca: European-Hematology-Association

FoxO1 transcription factor mediates toxicity of SYK inhibition in DLBCL

Autorzy: Kiliszek, P.; Szydlowski, M.; Sewastianik, T.; Bialopiotrowicz, E.; Jablonska, E.; Polak, A.; Prusisz, W.; Markowicz, S.; Nowak, E.; Grygorowicz, MA.; Bojarczuk, K.; Winiarska, M.; Golab, J.; Juszczynski, P.
Opublikowane w: HAEMATOLOGICA, 2014, Strona(/y) 137, Abstract: P430
Wydawca: European-Hematology-Association

HDAC6 inhibition augments the efficacy of anti-CD20 monoclonal antibodies by up-regulating CD20 level in malignant B-cells

Autorzy: Bobrowicz, M.; Dwojak, M.; Bojarczuk, K.; et al.
Opublikowane w: HAEMATOLOGICA, 2014, Strona(/y) 437, Abstract: P1143
Wydawca: European-Hematology-Association

Protein disulphide inhibitors induce differentiation of human acute myeloid leukemia cells

Autorzy: Chlebowska, J.; Firczuk, M.; Furs, K.; et al.
Opublikowane w: HAEMATOLOGICA, 2014, Strona(/y) 558, Abstract: PB1430
Wydawca: European-Hematology-Association

HDAC Inhibitors As Potential New Agents Improving the Efficacy of Monoclonal Antibodies

Autorzy: Bobrowicz, Malgorzata; Dwojak, Michal; Malenda, Agata; et al.
Opublikowane w: BLOOD, 2014
Wydawca: American-Society-of-Hematology

Influence of Btk Inhibitors on Antitumor Activity of Natural Killer Cells

Autorzy: Siernicka, Marta; Bojarczuk, Kamil; Bobrowicz, Malgorzata; et al.
Opublikowane w: BLOOD, 2014
Wydawca: American-Society-of-Hematology

SK053, an Inhibitor of Enzymes Involved in Allosteric Disulfide Bonds Formation, Targets Expression of Histone Genes and Induces Differentiation of Human AML Cell

Autorzy: Chlebowska, Justyna; Gaj, Pawel; Stawinski, Piotr; et al.
Opublikowane w: BLOOD, 2014
Wydawca: American-Society-of-Hematology

Peroxiredoxins-1 and 2 Affect Proliferation and Survival of Lymphoma Cells

Autorzy: Firczuk, Malgorzata; Trzeciecka, Anna; Bajor, Malgorzata; et al.
Opublikowane w: BLOOD, 2014
Wydawca: American-Society-of-Hematology

Inhibitors of B-Cell Receptor Molecules Affect Surface CD20 and Impair Antitumor Activity of Anti-CD20 Monoclonal Antibodies

Autorzy: Bojarczuk, Kamil; Winiarska, Magdalena; Bobrowicz, Malgorzata; et al.
Opublikowane w: BLOOD, 2013, Strona(/y) Abstract: 4217
Wydawca: American-Society-of-Hematology

SK053 An Inhibitor of Enzymes Involved In Allosteric Disulfide Bonds Formation Induces Differentiation of Human AML Cells

Autorzy: Chlebowska, Justyna; Firczuk, Malgorzata; Furs, Karolina; et al.
Opublikowane w: BLOOD, 2013, Strona(/y) Abstract: 4215
Wydawca: American-Society-of-Hematology

Inhibitors of SRC family and AKT regulate the activity of CD20 promoter

Autorzy: Pyrzynska B., Bojarczuk K., Winiarska M. Bil J. Miazek N. Zapala P., Bobrowicz M., Dwojak M., Siernicka M., Golab J.
Opublikowane w: BLOOD, 2013, Strona(/y) Abstract: 1838
Wydawca: American-Society-of-Hematology

A novel pathway regulating CD20 level influence of the inhibition of HDAC6 on the efficacy of anti-CD20 antibodies

Autorzy: Bobrowicz, M.; Dwojak, M.; Bojarczuk, K.; et al.
Opublikowane w: FEBS JOURNAL, 2014, Strona(/y) 239-240, Abstract: SUN-509
Wydawca: FEBS; EMBO

Regulation of CD20 levels in B-cell tumors by SRC family kinases

Autorzy: Bojarczuk, K.; Winiarska, M.; Bil, J.; et al.
Opublikowane w: FEBS JOURNAL, 2013, Strona(/y) 474
Wydawca: Federat European Biochemical Soc

Thiol-Reactive Peptidomimetic SK053 Targets Dimeric Peroxiredoxins in Human Lymphoma Cell Lines. Oral presentation.

Autorzy: Firczuk, M; Trzeciecka, A; Klosowski, S; et al.
Opublikowane w: Journal of International Society of Antioxidants in Health & Nutrition, 2015, Strona(/y) 43
Wydawca: International Society of Antioxidants

Regulation of CD20 levels in B-cell tumors by SRC family kinases

Autorzy: Bojarczuk, K.; Winiarska, M.; Bil, J.; et al.
Opublikowane w: FEBS JOURNAL, Numer 280, Special Numer: SI, Supplement: 1, 2013, Strona(/y) 474
Wydawca: Federat European Biochemical Soc

SK053, an Inhibitor of Enzymes Involved in Allosteric Disulfide Bonds Formation, Targets Expression of Histone Genes and Induces Differentiation of Human AML Cell

Autorzy: Chlebowska, Justyna; Gaj, Pawel; Stawinski, Piotr; et al.
Opublikowane w: BLOOD, Numer 124/21, 2014
Wydawca: American-Society-of-Hematology

Inhibitors of B-Cell Receptor Molecules Affect Surface CD20 and Impair Antitumor Activity of Anti-CD20 Monoclonal Antibodies

Autorzy: Bojarczuk, Kamil; Winiarska, Magdalena; Bobrowicz, Malgorzata; et al.
Opublikowane w: BLOOD, Numer 122/21, 2013, Strona(/y) Abstract: 4217
Wydawca: American-Society-of-Hematology

Ofatumumab overcomes CD59-dependent resistance to complement-dependent cytotoxicity in human B-cell lymphoma model

Autorzy: Dwojak, M.; Bobrowicz, M.; Siernicka, M.; et al.
Opublikowane w: HAEMATOLOGICA, Numer 100, Supplement: 1, 2015, Strona(/y) 552-552, Abstract: E1379
Wydawca: European-Hematology-Association

SK053-an allosteric protein disulphide isomerase inhibitor induces differentiation of human acute myeloid leukemia cells

Autorzy: Golab, J.; Chlebowska, J.; Firczuk, M.; et al.
Opublikowane w: HAEMATOLOGICA, Numer 99, Supplement: 1, 2014, Strona(/y) 296, Abstract: P809
Wydawca: European-Hematology-Association

NK cells cytotoxicity is affected by various BTK inhibitors

Autorzy: Siernicka, M.; Bojarczuk, K.; Bobrowicz, M.; et al.
Opublikowane w: HAEMATOLOGICA, Numer 100, Supplement: 1, 2015, Strona(/y) 549-550, Abstract: E1372
Wydawca: European-Hematology-Association

MEK1 inhibitor selumetinib sensitizes B-cell Acute Lymphoblastic Leukemia (B-ALL) cells to dexamethasone by modulating autophagy

Autorzy: Polak, A.; Kiliszek, P.; Sewastianik, T.; Szydlowski, M.; Jablonska, E.; Prusisz, W.; Bialopiotrowicz, E.; Markowicz, S.; Nowak, E.; Grygorowicz, M.; Nowis, D.; Bojarczuk, K.; Golab, J.; Juszczynski, P.
Opublikowane w: HAEMATOLOGICA, Numer 99, Supplement: 1, 2014, Strona(/y) 272, Abstract: P751
Wydawca: European-Hematology-Association

B-cell receptor pathway inhibitors affect CD20 levels and impair antitumor activity of anti-CD20 monoclonal antibodies

Autorzy: K Bojarczuk, M Siernicka, M Dwojak, M Bobrowicz, B Pyrzynska, P Gaj, M Karp, K Giannopoulos, D G Efremov, C Fauriat, J Golab, M Winiarska
Opublikowane w: Leukemia, Numer 28/5, 2014, Strona(/y) 1163-1167, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/leu.2014.12

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis

Autorzy: Witold W. Kilarski, Angelika Muchowicz, Malgorzata Wachowska, Renata Mężyk-Kopeć, Jakub Golab, Melody A. Swartz, Patrycja Nowak-Sliwinska
Opublikowane w: Angiogenesis, Numer 17/2, 2014, Strona(/y) 347-357, ISSN 0969-6970
Wydawca: Kluwer Academic Publishers
DOI: 10.1007/s10456-013-9365-6

Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells

Autorzy: Marta Siernicka, Magdalena Winiarska, Malgorzata Bajor, Malgorzata Firczuk, Angelika Muchowicz, Malgorzata Bobrowicz, Cyril Fauriat, Jakub Golab, Daniel Olive, Radoslaw Zagozdzon
Opublikowane w: Immunology, Numer 146/1, 2015, Strona(/y) 173-183, ISSN 0019-2805
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/imm.12494

Iron Chelators in Photodynamic Therapy Revisited: Synergistic Effect by Novel Highly Active Thiosemicarbazones

Autorzy: Anna Mrozek-Wilczkiewicz, Maciej Serda, Robert Musiol, Grzegorz Malecki, Agnieszka Szurko, Angelika Muchowicz, Jakub Golab, Alicja Ratuszna, Jaroslaw Polanski
Opublikowane w: ACS Medicinal Chemistry Letters, Numer 5/4, 2014, Strona(/y) 336-339, ISSN 1948-5875
Wydawca: American Chemical Society
DOI: 10.1021/ml400422a

Review Cancer stem cells in haematological malignancies

Autorzy: Radoslaw Zagozdzon, Jakub Golab
Opublikowane w: Współczesna Onkologia, Numer 1A, 2015, Strona(/y) 1-6, ISSN 1428-2526
Wydawca: Termedia
DOI: 10.5114/wo.2014.47127

Abstract LB-242: PTEN regulates the CD20 antigen expression and affects rituximab-based therapy of lymphoma malignancies

Autorzy: Beata Pyrzynska, Kamil Bojarczuk, Marta Siernicka, Michal Dwojak, Malgorzata Bobrowicz, Nina Miazek, Piotr Zapala, Agnieszka Zagozdzon, Jakub Golab, Magdalena Winiarska
Opublikowane w: Cancer Research, Numer 75/15 Supplement, 2015, Strona(/y) LB-242-LB-242, ISSN 0008-5472
Wydawca: American Association for Cancer Research
DOI: 10.1158/1538-7445.AM2015-LB-242

Abstract P5-07-09: Adenanthin, a new peroxiredoxin inhibitor, induces a switch between estrogen receptor alpha-mediated and Src/Akt-driven signaling in breast cancer cells

Autorzy: Malgorzata Bajor, Agata O Zych, Patrick C O'Leary, Anna Czekalska, William M Gallagher, Jakub Golab, Radoslaw Zagozdzon
Opublikowane w: Cancer Research, Numer 75/9 Supplement, 2015, Strona(/y) P5-07-09-P5-07-09, ISSN 0008-5472
Wydawca: American Association for Cancer Research
DOI: 10.1158/1538-7445.SABCS14-P5-07-09

Epigenetic remodeling combined with photodynamic therapy elicits anticancer immune responses

Autorzy: Malgorzata Wachowska, Magdalena Gabrysiak, Jakub Golab
Opublikowane w: OncoImmunology, Numer 3/5, 2014, Strona(/y) e28837, ISSN 2162-402X
Wydawca: Landes Bioscience, Austin, TX
DOI: 10.4161/onci.28837

Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model

Autorzy: Izabela Mlynarczuk-Bialy, Thorsten R. Doeppner, Jakub Golab, Dominika Nowis, Grzegorz M. Wilczynski, Kamil Parobczak, Moritz E. Wigand, Malgorzata Hajdamowicz, Łukasz P. Biały, Olga Aniolek, Petra Henklein, Mathias Bähr, Boris Schmidt, Ulrike Kuckelkorn, Peter-M. Kloetzel
Opublikowane w: Translational Oncology, Numer 7/5, 2014, Strona(/y) 570-579, ISSN 1936-5233
Wydawca: Neoplasia Press
DOI: 10.1016/j.tranon.2014.07.002

Sorafenib improves rituximab and ofatumumab efficacy by decreasing the expression of complement regulatory proteins

Autorzy: M Dwojak, M Bobrowicz, J Bil, K Bojarczuk, B Pyrzynska, M Siernicka, A Malenda, E Lech-Maranda, W Tomczak, K Giannopoulos, J Golab, M Winiarska
Opublikowane w: Blood Cancer Journal, Numer 5/4, 2015, Strona(/y) e300, ISSN 2044-5385
Wydawca: Nature Publishing Group
DOI: 10.1038/bcj.2015.27

Statins impair glucose uptake in human cells

Autorzy: D. Nowis, A. Malenda, K. Furs, B. Oleszczak, R. Sadowski, J. Chlebowska, M. Firczuk, J. M. Bujnicki, A. D. Staruch, R. Zagozdzon, E. Glodkowska-Mrowka, L. Szablewski, J. Golab
Opublikowane w: BMJ Open Diabetes Research & Care, Numer 2/1, 2014, Strona(/y) e000017-e000017, ISSN 2052-4897
Wydawca: BMJ in partnership with the American Diabetes Association
DOI: 10.1136/bmjdrc-2014-000017

Interleukin 12: still a promising candidate for tumor immunotherapy?

Autorzy: Witold Lasek, Radosław Zagożdżon, Marek Jakobisiak
Opublikowane w: Cancer Immunology, Immunotherapy, Numer 63/5, 2014, Strona(/y) 419-435, ISSN 0340-7004
Wydawca: Springer Verlag
DOI: 10.1007/s00262-014-1523-1

Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

Autorzy: Patrick C O’Leary, Marta Terrile, Malgorzata Bajor, Pawel Gaj, Bryan T Hennessy, Gordon B Mills, Agnieszka Zagozdzon, Darran P O’Connor, Donal J Brennan, Kate Connor, Jane Li, Ana Gonzalez-Angulo, Han-Dong Sun, Jian-Xin Pu, Fredrik Pontén, Mathias Uhlén, Karin Jirström, Dominika A Nowis, John P Crown, Radoslaw Zagozdzon, William M Gallagher
Opublikowane w: Breast Cancer Research, Numer 16/4, 2014, Strona(/y) R79, ISSN 1465-5411
Wydawca: BioMed Central
DOI: 10.1186/bcr3691

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Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy

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Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL

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Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

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Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans

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Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA

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Cognate HLA absence in trans diminishes human NK cell education

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Targeting Epigenetic Processes in Photodynamic Therapy-Induced Anticancer Immunity

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Review Cancer stem cells in haematological malignancies

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Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells

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Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies

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Biodistribution and Efficacy Studies of the Proteasome Inhibitor BSc2118 in a Mouse Melanoma Model

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Exploring the Anti-Cancer Activity of Novel Thiosemicarbazones Generated through the Combination of Retro-Fragments: Dissection of Critical Structure-Activity Relationships

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Iron Chelators in Photodynamic Therapy Revisited: Synergistic Effect by Novel Highly Active Thiosemicarbazones

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B-cell receptor pathway inhibitors affect CD20 levels and impair antitumor activity of anti-CD20 monoclonal antibodies

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Danger signalling during cancer cell death: origins, plasticity and regulation

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5-Aza-2′-deoxycytidine potentiates antitumour immune response induced by photodynamic therapy

Autorzy: Malgorzata Wachowska, Magdalena Gabrysiak, Angelika Muchowicz, Weronika Bednarek, Joanna Barankiewicz, Tomasz Rygiel, Louis Boon, Pawel Mroz, Michael R Hamblin, Jakub Golab
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Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis

Autorzy: Witold W. Kilarski, Angelika Muchowicz, Malgorzata Wachowska, Renata Mężyk-Kopeć, Jakub Golab, Melody A. Swartz, Patrycja Nowak-Sliwinska
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GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

Autorzy: M Firczuk, M Gabrysiak, J Barankiewicz, A Domagala, D Nowis, M Kujawa, E Jankowska-Steifer, M Wachowska, E Glodkowska-Mrowka, B Korsak, M Winiarska, J Golab
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Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

Autorzy: Patrick C O’Leary, Marta Terrile, Malgorzata Bajor, Pawel Gaj, Bryan T Hennessy, Gordon B Mills, Agnieszka Zagozdzon, Darran P O’Connor, Donal J Brennan, Kate Connor, Jane Li, Ana Gonzalez-Angulo, Han-Dong Sun, Jian-Xin Pu, Fredrik Pontén, Mathias Uhlén, Karin Jirström, Dominika A Nowis, John P Crown, Radoslaw Zagozdzon, William M Gallagher
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Interleukin 12: still a promising candidate for tumor immunotherapy?

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Antitumor Immunity Triggered by Melphalan Is Potentiated by Melanoma Cell Surface-Associated Calreticulin

Autorzy: A. M. Dudek-Peri , G. B. Ferreira, A. Muchowicz, J. Wouters, N. Prada, S. Martin, S. Kiviluoto, M. Winiarska, L. Boon, C. Mathieu, J. van den Oord, M. Stas, M.-L. Gougeon, J. Golab, A. D. Garg, P. Agostinis
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In silico analysis of microRNA-510 as a potential oncomir in human breast cancer

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Epigenetic remodeling combined with photodynamic therapy elicits anticancer immune responses

Autorzy: Malgorzata Wachowska, Magdalena Gabrysiak, Jakub Golab
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Abstract LB-242: PTEN regulates the CD20 antigen expression and affects rituximab-based therapy of lymphoma malignancies

Autorzy: Beata Pyrzynska, Kamil Bojarczuk, Marta Siernicka, Michal Dwojak, Malgorzata Bobrowicz, Nina Miazek, Piotr Zapala, Agnieszka Zagozdzon, Jakub Golab, Magdalena Winiarska
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Abstract P5-07-09: Adenanthin, a new peroxiredoxin inhibitor, induces a switch between estrogen receptor alpha-mediated and Src/Akt-driven signaling in breast cancer cells

Autorzy: Malgorzata Bajor, Agata O Zych, Patrick C O'Leary, Anna Czekalska, William M Gallagher, Jakub Golab, Radoslaw Zagozdzon
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Targeting Epigenetic Processes in Photodynamic Therapy-Induced Anticancer Immunity

Autorzy: Malgorzata Wachowska, Angelika Muchowicz, Jakub Golab
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GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

Autorzy: M Firczuk, M Gabrysiak, J Barankiewicz, A Domagala, D Nowis, M Kujawa, E Jankowska-Steifer, M Wachowska, E Glodkowska-Mrowka, B Korsak, M Winiarska, J Golab
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Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies

Autorzy: Magdalena Winiarska, Kamil Bojarczuk, Beata Pyrzynska, Jacek Bil, Marta Siernicka, Michal Dwojak, Malgorzata Bobrowicz, Nina Miazek, Piotr Zapala, Agnieszka Zagozdzon, Magdalena Krol, Aleksandra Syta, Paulina Podszywalow-Bartnicka, Zofia Pilch, Anna Dabrowska-Iwanicka, Przemyslaw Juszczynski, Dimitar G Efremov, Mikolaj Slabicki, Thorsten Zenz, Aude Le Roy, Daniel Olive, Tomasz P Rygiel, Jeanette HW Leusen, Jakub Golab
Opublikowane w: mAbs, Numer 6/5, 2014, Strona(/y) 1300-1313, ISSN 1942-0870
Wydawca: Landes Bioscience
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Danger signalling during cancer cell death: origins, plasticity and regulation

Autorzy: A D Garg, S Martin, J Golab, P Agostinis
Opublikowane w: Cell Death and Differentiation, Numer 21/1, 2013, Strona(/y) 26-38, ISSN 1350-9047
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Antitumor Immunity Triggered by Melphalan Is Potentiated by Melanoma Cell Surface-Associated Calreticulin

Autorzy: A. M. Dudek-Peri , G. B. Ferreira, A. Muchowicz, J. Wouters, N. Prada, S. Martin, S. Kiviluoto, M. Winiarska, L. Boon, C. Mathieu, J. van den Oord, M. Stas, M.-L. Gougeon, J. Golab, A. D. Garg, P. Agostinis
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Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

Autorzy: Abhishek D. Garg, Lorenzo Galluzzi, Lionel Apetoh, Thais Baert, Raymond B. Birge, José Manuel Bravo-San Pedro, Karine Breckpot, David Brough, Ricardo Chaurio, Mara Cirone, An Coosemans, Pierre G. Coulie, Dirk De Ruysscher, Luciana Dini, Peter de Witte, Aleksandra M. Dudek-Peric, Alberto Faggioni, Jitka Fucikova, Udo S. Gaipl, Jakub Golab, Marie-Lise Gougeon, Michael R. Hamblin, Akseli Hemminki, Martin Herrmann, James W. Hodge, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, Walter G. Land, Frank Madeo, Angelo A. Manfredi, Stephen R. Mattarollo, Christian Maueroder, Nicolò Merendino, Gabriele Multhoff, Thomas Pabst, Jean-Ehrland Ricci, Chiara Riganti, Erminia Romano, Nicole Rufo, Mark J. Smyth, Jürgen Sonnemann, Radek Spisek, John Stagg, Erika Vacchelli, Peter Vandenabeele, Lien Vandenberk, Benoit J. Van den Eynde, Stefaan Van Gool, Francesca Velotti, Laurence Zitvogel, Patrizia Agostinis
Opublikowane w: Frontiers in Immunology, Numer 6, 2015, Strona(/y) 588, ISSN 1664-3224
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Influence of BCR inhibitors on CD20 regulation in tumor cells

Autorzy: Kamil Bojarczuk; Supervisor 1: Dominika Nowis, MD, PhD; Supervisor 2: Magdalena Winiarska, PhD
Opublikowane w: 2015
Wydawca: Medical University of Warsaw, I Faculty of Medicine, Warsaw

Influence of BCR inhibitors on CD20 regulation in tumor cells

Autorzy: Kamil Bojarczuk; Supervisor 1: Dominika Nowis, MD, PhD; Supervisor 2: Magdalena Winiarska, PhD
Opublikowane w: 2015
Wydawca: Medical University of Warsaw, I Faculty of Medicine, Warsaw

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