European Research Training to Decipher The Ub Code : identification of potential biomarkers and drug targets

SUMO-ID: A Strategy for the Identification of SUMO-Dependent Proximal Interactors

Autorzy: Orhi Barroso-Gomila, Ugo Mayor, Rosa Barrio & James D. Sutherland
Opublikowane w: 2022
Wydawca: Springer Protocols
DOI: 10.1007/978-1-0716-2859-1_13

Total Linear Chemical Synthesis of LC3A and LC3B

Autorzy: Yara Huppelschoten, Jens Buchardt, Thomas Eiland Nielsen & Gerbrand J. van der Heden van Noort
Opublikowane w: Methods in Molecular Biology, Numer 2602, 2022
Wydawca: Springer Protocols
DOI: 10.1007/978-1-0716-2859-1_4

Chemical Synthesis of Non-hydrolyzable Ubiquitin(-Like) Hybrid Chains

Autorzy: David A. Pérez Berrocal, Gerbrand J. van der Heden van Noort & Monique P. C. Mulder
Opublikowane w: Methods in Molecular Biology, Numer 2602, 2022
Wydawca: Springer Protocols
DOI: 10.1007/978-1-0716-2859-1_3

Isolation and Mass Spectrometry Identification of K48 and K63 Ubiquitin Proteome Using Chain-Specific Nanobodies

Autorzy: Maria Gonzalez-Santamarta, Laurie Ceccato, Ana Sofia Carvalho, Jean-Christophe Rain, Rune Matthiesen & Manuel S. Rodriguez
Opublikowane w: 2022
Wydawca: Springer Protocols
DOI: 10.1007/978-1-0716-2859-1_9

Biotin-based approaches for the study of SUMO and Ubiquitin modifications

Autorzy: Sutherland, JD; O, Barroso-Gomila; Barrio, R
Opublikowane w: Numer 3, 2019
Wydawca: Caister Academic Press
DOI: 10.5281/zenodo.3601585

Biochemical characterization of SUMO-conjugating enzymes by in vitro sumoylation assays

Autorzy: Nathalie Eisenhardt, Dragana Ilic, Easa Nagamalleswari, Andrea Pichler
Opublikowane w: Ubiquitin and Ubiquitin-like Protein Modifiers, Numer 618, 2019, Strona(/y) 167-185, ISBN 9780-128163597
Wydawca: Elsevier
DOI: 10.1016/bs.mie.2018.12.025

Biotin-based Approaches for the Study of Ubiquitin and Ubiquitin-like Protein Modifications

Autorzy: James D. Sutherland, Orhi Barroso Gomila, Rosa Barrio
Opublikowane w: SUMOylation and Ubiquitination: Current and Emerging Concepts, 2019, ISBN 9781-912530120
Wydawca: Caister Academic Press
DOI: 10.21775/9781912530120.07

Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma

Autorzy: Maria Gonzalez-Santamarta, Grégoire Quinet, Diana Reyes-Garau, Brigitte Sola, Gaël Roué, Manuel S. Rodriguez
Opublikowane w: Proteostasis and Disease - From Basic Mechanisms to Clinics, Numer 1233, 2020, Strona(/y) 153-174, ISBN 978-3-030-38265-0
Wydawca: Springer International Publishing
DOI: 10.1007/978-3-030-38266-7_6

Role of Sumoylation in Neurodegenerative Diseases and Inflammation

Autorzy: Esmeralda Parra-Peralbo, Veronica Muratore, Orhi Barroso-Gomila, Ana Talamillo, James D. Sutherland, Rosa Barrio
Opublikowane w: 2021
Wydawca: CRC Press
DOI: 10.1201/9781003048138-08

Structural mechanism of cGAS inhibition by the nucleosome

Autorzy: Ganesh R. Pathare, Alexiane Decout, Selene Glück, Simone Cavadini, Kristina Makasheva, Ruud Hovius, Georg Kempf, Joscha Weiss, Zuzanna Kozicka, Baptiste Guey, Pauline Melenec, Beat Fierz, Nicolas H. Thomä, Andrea Ablasser
Opublikowane w: Nature, Numer 587/7835, 2020, Strona(/y) 668-672, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-020-2750-6

Identification of proximal SUMO-dependent interactors using SUMO-ID

Autorzy: Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland
Opublikowane w: Nature Communications, Numer 12, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-26807-6

The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

Autorzy: Tom Cremer, Marlieke L.M. Jongsma, Fredrik Trulsson, Alfred C.O. Vertegaal, Jacques Neefjes, Ilana Berlin
Opublikowane w: Cell Reports, Numer 34/3, 2021, Strona(/y) 108659, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2020.108659

Rational discovery of molecular glue degraders via scalable chemical profiling

Autorzy: Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H. Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C. Müller, Johannes Zuber, Matthias Geyer, Nicolas H. Thomä, Stefan Kubicek, Georg E. Winter
Opublikowane w: Nature Chemical Biology, Numer 16/11, 2020, Strona(/y) 1199-1207, ISSN 1552-4450
Wydawca: Nature Publishing Group
DOI: 10.1038/s41589-020-0594-x

The role of SUMOylation during development

Autorzy: Ana Talamillo, Orhi Barroso-Gomila, Immacolata Giordano, Leiore Ajuria, Marco Grillo, Ugo Mayor, Rosa Barrio
Opublikowane w: Biochemical Society Transactions, Numer 48/2, 2020, Strona(/y) 463-478, ISSN 0300-5127
Wydawca: Portland Press, Ltd.
DOI: 10.1042/bst20190390

Haven't got a glue: Protein surface variation for the design of molecular glue degraders

Autorzy: Zuzanna Kozicka, Nicolas Holger Thomä
Opublikowane w: Cell Chemical Biology, 2021, ISSN 2451-9456
Wydawca: Cell Press
DOI: 10.1016/j.chembiol.2021.04.009

Deubiquitinating enzymes and the proteasome regulate preferential sets of ubiquitin substrates

Autorzy: Fredrik Trulsson; Vyacheslav Akimov; Mihaela Robu; Nila van Overbeek; David Aureliano Pérez Berrocal; Rashmi G. Shah; Jürgen Cox; Girish M. Shah; Blagoy Blagoev; Alfred C. O. Vertegaal
Opublikowane w: Nature Communication, Numer 13, 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-022-30376-7

SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes

Autorzy: Immacolata Giordano, Lucia Pirone, Veronica Muratore, Eukene Landaluze, Coralia Pérez, Valerie Lang, Elisa Garde-Lapido, Monika Gonzalez-Lopez, Orhi Barroso-Gomila, Alfred C O Vertegaal, Ana M Aransay, Jose Antonio Rodriguez, Manuel S Rodriguez, James D Sutherland, Rosa Barrio
Opublikowane w: Frontiers in Cell and Developmental Biology, 2021, ISSN 2296-634X
Wydawca: Frontiers
DOI: 10.3389/fcell.2021.715868

Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code

Autorzy: David A. Pérez Berrocal, Katharina F. Witting, Huib Ovaa, Monique P. C. Mulder
Opublikowane w: Frontiers in Chemistry, Numer 7, 2020, ISSN 2296-2646
Wydawca: Frontiers in biochemistry
DOI: 10.3389/fchem.2019.00931

Taking the Brakes Off Targeted Protein Degradation

Autorzy: Zuzanna Kozicka, Georg Petzold, Nicolas H. Thomä
Opublikowane w: Cell Chemical Biology, Numer 27/1, 2020, Strona(/y) 16-18, ISSN 2451-9456
Wydawca: Cell Press
DOI: 10.1016/j.chembiol.2019.12.010

Mechanisms of OCT4-SOX2 motif readout on nucleosomes

Autorzy: Alicia K. Michael, Ralph S. Grand, Luke Isbel, Simone Cavadini, Zuzanna Kozicka, Georg Kempf, Richard D. Bunker, Andreas D. Schenk, Alexandra Graff-Meyer, Ganesh R. Pathare, Joscha Weiss, Syota Matsumoto, Lukas Burger, Dirk Schübeler, Nicolas H. Thomä
Opublikowane w: Science, 2020, Strona(/y) eabb0074, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.abb0074

Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy

Autorzy: Grégoire Quinet, Maria Gonzalez-Santamarta, Clara Louche, Manuel S. Rodriguez
Opublikowane w: Molecules, Numer 25/10, 2020, Strona(/y) 2352, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25102352

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

Autorzy: Mikołaj Słabicki, Zuzanna Kozicka, Georg Petzold, Yen-Der Li, Manisha Manojkumar, Richard D. Bunker, Katherine A. Donovan, Quinlan L. Sievers, Jonas Koeppel, Dakota Suchyta, Adam S. Sperling, Emma C. Fink, Jessica A. Gasser, Li R. Wang, Steven M. Corsello, Rob S. Sellar, Max Jan, Dennis Gillingham, Claudia Scholl, Stefan Fröhling, Todd R. Golub, Eric S. Fischer, Nicolas H. Thomä, Benjamin L. E
Opublikowane w: Nature, 2020, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-020-2374-x

SUMOylation in the control of cholesterol homeostasis

Autorzy: Ana Talamillo, Leiore Ajuria, Marco Grillo, Orhi Barroso-Gomila, Ugo Mayor, Rosa Barrio
Opublikowane w: Open Biology, Numer 10/5, 2020, Strona(/y) 200054, ISSN 2046-2441
Wydawca: Royal Society Publishing
DOI: 10.1098/rsob.200054

LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome

Autorzy: Laura Bozal-Basterra, María Gonzalez-Santamarta, Veronica Muratore, Aitor Bermejo-Arteagabeitia, Carolina Da Fonseca, Orhi Barroso-Gomila, Mikel Azkargorta, Ibon Iloro, Olatz Pampliega, Ricardo Andrade, Natalia Martín-Martín, Tess C Branon, Alice Y Ting, Jose A Rodríguez, Arkaitz Carracedo, Felix Elortza, James D Sutherland, Rosa Barrio
Opublikowane w: eLife, Numer 9, 2020, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.55957

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection

Autorzy: Robbert Q. Kim, Mohit Misra, Alexis Gonzalez, Ines Tomašković, Donghyuk Shin, Hermann Schindelin, Dmitri V. Filippov, Huib Ovaa, Ivan Đikić, Gerbrand J. Heden van Noort
Opublikowane w: Chemistry – A European Journal, Numer 27/7, 2021, Strona(/y) 2506-2512, ISSN 0947-6539
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202004590

Inhibition of the proteasome and proteaphagy enhances apoptosis in FLT3‐ITD‐driven acute myeloid leukemia

Autorzy: Rosa G. Lopez‐Reyes, Grégoire Quinet, Maria Gonzalez‐Santamarta, Clément Larrue, Jean‐Emmanuel Sarry, Manuel S. Rodriguez
Opublikowane w: FEBS Open Bio, Numer 11/1, 2021, Strona(/y) 48-60, ISSN 2211-5463
Wydawca: Elsevier BV
DOI: 10.1002/2211-5463.12950

Identification of SUMO Targets Associated With the Pluripotent State in Human Stem Cells

Autorzy: Barbara Mojsa; Michael H. Tatham; Lindsay Davidson; Magda Liczmanska; Emma Branigan; Ronald T. Hay
Opublikowane w: Molecular and Cellular Proteomics, Numer 1, 2021, ISSN 1535-9476
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2021.100164

Studying the ubiquitin code through biotin-based labelling methods

Autorzy: Orhi Barroso-Gomila, Veronica Muratore, Laura Merino-Cacho, Jose Antonio Rodriguez, Rosa Barrio, James D. Sutherland
Opublikowane w: Seminars in Cell & Developmental Biology, 2022, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2022.02.009

Fast friends – Ubiquitin-like modifiers as engineered fusion partners

Autorzy: Evrydiki Asimaki, Kirill Petriukov, Christian Renz, Cindy Meister, Helle D.Ulrich
Opublikowane w: Seminars in Cell & Developmental Biology, 2021, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2021.11.013

Site-specific proteomic strategies to identify ubiquitin and SUMO modifications: Challenges and opportunities

Autorzy: Fredrik Trulsson, Alfred C. O. Vertegaal
Opublikowane w: Seminars in Cell and Developmental Biology, 2021, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2021.11.006

Membrane compartmentalisation of the ubiquitin system

Autorzy: Emma V. Rusilowicz-Jones; Ailbhe J. Brazel; Francesca Frigenti; Sylvie Urbé; Michael J. Clague
Opublikowane w: Seminars in Cell & Developmental Biology, 2021, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2021.11.016

Ubiquitin-chains dynamics and its role regulating crucial cellular processes

Autorzy: Maria Gonzalez-Santamarta, Corentin Bouvier, Manuel S. Rodriguez and Wendy Xolalpa
Opublikowane w: Seminars in Cell & Developmental Biology, 2021, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2021.11.023

Chemical biology tools to study Deubiquitinases and Ubl proteases

Autorzy: Magdalena Gorka; Helge Magnus Magnussen; Yogesh Kulathu
Opublikowane w: Seminars in Cell & Developmental Biology, Numer 1, 2022, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2022.02.006

State of the art in (semi-)synthesis of Ubiquitin- and Ubiquitin-like tools

Autorzy: Yara Huppelschoten, Gerbrand J.van der Heden van Noort
Opublikowane w: Seminars in Cell & Developmental Biology, 2021, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2021.11.025

Ubiquitin and Legionella: From bench to bedside

Autorzy: Ines Tomaskovic; Alexis Gonzalez; Ivan Dikic
Opublikowane w: Seminars in Cell & Developmental Biology, Numer 1, 2022, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2022.02.008

Stress - Regulation of SUMO conjugation and of other Ubiquitin‐Like Modifiers

Autorzy: Dragana Ilic, Helge M. Magnussen, Marilyn Tirard
Opublikowane w: Seminars in Cell & Developmental Biology, 2022, ISSN 1084-9521
Wydawca: Academic Press
DOI: 10.1016/j.semcdb.2021.12.010

SUMO maintains the chromatin environment of human induced pluripotent stem cells

Autorzy: Barbara Mojsa; Michael H. Tatham; Lindsay Davidson; Magda Liczmanska; Jane E. Wright; Nicola Wiechens; Marek Gierlinski; Tom Owen-Hughes; Ronald T. Hay
Opublikowane w: bioRxiv, 2021
Wydawca: bioRxiv
DOI: 10.1101/2020.12.22.423944

Identification of proximal SUMO-dependent interactors using SUMO-ID

Autorzy: Orhi Barroso-Gomila; Fredrik Trulsson; Veronica Muratore; Iñigo Canosa; Ana Rosa Cortazar; Coralia Perez; Mikel Azkargorta; Ibon Iloro; Arkaitz Carracedo; Ana M Aransay; Felix Elortza; Ugo Mayor; Alfred C. O. Vertegaal; Rosa Barrio; James D. Sutherland
Opublikowane w: bioRxiv, 2020
Wydawca: bioRxiv
DOI: 10.1101/2020.12.28.424528

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