Volatolomics test for the diagnosis of bovine tuberculosis

Informacje na temat projektu

bTB-Test

Identyfikator umowy o grant: 777832

DOI

10.3030/777832

Realizacja projektu zakończyła się 31 Grudnia 2019

Data podpisania przez KE 17 Października 2017

Data rozpoczęcia 1 Stycznia 2018

Data zakończenia 31 Grudnia 2021

Finansowanie w ramach

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Koszt całkowity

€ 1 404 000,00

Wkład UE

€ 1 395 000,00

Koordynowany przez

UPPSALA UNIVERSITET
Sweden

Periodic Reporting for period 1 - bTB-Test (Volatolomics test for the diagnosis of bovine tuberculosis)

Okres sprawozdawczy: 2018-01-01 do 2019-12-31

Podsumowanie kontekstu i ogólnych celów projektu

Bovine tuberculosis is a serious global disease with significant impact on animal health, public health, and international trade. Bovine tuberculosis can be transmitted to humans by drinking unpasteurized milk from an infected cow or eating raw or undercooked meat from an infected animal. Therefore, accurate and efficient detection of bovine tuberculosis in animal populations remains of paramount importance for bovine tuberculosis control programs. The overall objective of this project is the development a new diagnosis test for bovine tuberculosis, suitable for being performed directly on the premises in an inexpensive, fast and non-invasive way, from the analysis of volatile compounds emitted by biological samples such as breath, feces and animals skin.

Prace wykonane od początku projektu do końca okresu sprawozdawczego oraz najważniejsze dotychczasowe rezultaty

It was elaborated an optimized protocol for the collection of volatile samples emitted through the breath, feces and skin of cattle. Based on this protocol, 400 animals were samples in different countries from different continents: Romania, Tunisia, Algeria and Colombia. The analytical studies of the samples led to the identification of 6 tentative volatile biomarkers of bovine tuberculosis emitted through cattle breath, 13 tentative volatile biomarkers emitted through cattle feces, and 3 tentative volatile biomarkers emitted through cattle skin.

Innowacyjność oraz oczekiwany potencjalny wpływ (w tym dotychczasowe znaczenie społeczno-gospodarcze i szersze implikacje społeczne projektu)

This is the first time that volatile biomarkers emitted through cattle feces and skin were proposed. The results of this project could lead to a new, non-invasive and faster test for the diagnosis of bovine tuberculosis in cattle, with great impact on the livestock management.

Skin volatiles sampling

Breath sampling