Opis projektu
Utilising kidney organoids in the search for new diabetic nephropathy therapies
Nephropathy is a major diabetes morbidity that often progresses to end-stage renal disease as there are no available treatments apart from glycaemic and blood pressure control strategies. To address this limitation, the EU-funded EPIORGABOLISM project is working on a novel diabetic nephropathy model that has the potential to assist future drug discovery efforts. Researchers will use human embryonic stem cells to derive kidney organoids and study how the metabolic alterations in diabetes can epigenetically reprogramme kidney cells and cause fibrosis. Results will provide important insight into disease pathology and progression and help identify novel therapeutic targets.
Dziedzina nauki
- /medycyna i nauki o zdrowiu/medycyna kliniczna/endokrynologia/cukrzyca/nefropatia cukrzycowa
- /nauki przyrodnicze/nauki biologiczne/biochemia/biocząsteczki/lipidy
Program(-y)
Temat(-y)
Zaproszenie do składania wniosków
H2020-MSCA-IF-2017
Zobacz inne projekty w ramach tego zaproszenia
System finansowania
MSCA-IF-EF-RI - RI – Reintegration panel
Koordynator
08028 Barcelona
Hiszpania