Excel in Rare Diseases’ Research: Focus on LYSOsomal Disorders and CILiopathies

Rezultaty

D7.8 - LYSOCIL Final conference

Final conference at UNLNMSCEDOC ll the participants and steakholders related to RDs

D7.3 - Communication and promotional materials I

Informative brochures, presentations and movies on RDs

D7.2 - Project website launch and Visual Identity Guide

Creation of our Website with information on RDs and our visual logotype.

D7.6 - e-LYSOCIL RDs Research HUB launch

Website where partners can communicate, share and deposit research outputs for the general public.

D7.4 - Communication and promotional materials II

Informative brochures presentations and movies on RDs

D7.5 - Communication and promotional materials III

Informative brochures presentations and movies on RDs

Publikacje

SymmetryBreaking Cilia-Driven Flow in Embryogenesis

Autorzy: David J. Smith, Thomas D. Montenegro-Johnson, Susana S. Lopes
Opublikowane w: Annual Review of Fluid Mechanics, 2018, ISSN 0066-4189
Wydawca: Annual Reviews, Inc.
DOI: 10.1146/annurev-fluid-010518-040231

Pkd2 affects cilia length and impacts left-right flow dynamics and dand5 (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Raquel Jacinto, Pedro Sampaio, Mónica Roxo-Rosa, Sara Pestana, Susana S Lopes
Opublikowane w: Front Cell Dev Biol, 2021, ISSN 2296-634X
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.624531

Zebrafish motile cilia as a model for Primary Ciliary Dyskinesia (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Andreia L Pinto, Margarida Rasteiro, Catarina Bota, Sara Pestana, Pedro Sampaio, Claire Hogg, Thomas Burgoyne, Susana S Lopes
Opublikowane w: Int J Mol Sci, Numer 22/16, 2021, ISSN 1661-6596
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22168361

Rab35 controls cilium length, function and membrane composition (project related publication after the start date of LYSOCIL project, RP1)

Autorzy: Stefanie Kuhns, Cecília Seixas, Sara Pestana, Bárbara Tavares, Renata Nogueira, Raquel Jacinto, José S Ramalho, Jeremy C Simpson, Jens S Andersen, Arnaud Echard, Susana S Lopes, Duarte C Barral, Oliver E Blacque
Opublikowane w: EMBO reports, Numer 20/10, 2019, ISSN 1469-221X
Wydawca: Nature Publishing Group
DOI: 10.15252/embr.201847625

Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Cristina Escrevente, Liliana Bento-Lopes, José S Ramalho, Duarte C Barral
Opublikowane w: J Cell Sci, Numer 134/11, 2021, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.246694

Formation of lipofuscin-like autofluorescent granules in the retinal pigment epithelium requires lysosome dysfunction (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Cristina Escrevente, Ana S Falcão, Michael J Hall, Mafalda Lopes-da-Silva, Pedro Antas, Miguel M Mesquita, Inês S Ferreira, M Helena Cardoso, Daniela Oliveira, Ana C Fradinho, Thomas Ciossek, Paul Nicklin, Clare E Futter, Sandra Tenreiro, Miguel C Seabra
Opublikowane w: Invest Ophthalmol Vis Sci, Numer 62/9, 2021, ISSN 0146-0404
Wydawca: Association for Research in Vision and Ophthalmology
DOI: 10.1167/iovs.62.9.39

Melanocore uptake by keratinocytes occurs through phagocytosis and involves protease-activated receptor-2 internalization (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Hugo Moreiras ,Liliana Bento-Lopes, Matilde V. Neto, Cristina Escrevente, Luís C. Cabaço, Michael J. Hall, José S. Ramalho, Miguel C. Seabra, Duarte C. Barral
Opublikowane w: Traffic, Numer 6, 2022, ISSN 1398-9219
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/tra.12843

Current methods to analyze lysosome morphology, positioning, motility and function (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Duarte C Barral, Leopoldo Staiano, Cláudia Guimas Almeida, Dan F Cutler, Emily R Eden, Clare E Futter, Antony Galione, André R A Marques, Diego Luis Medina, Gennaro Napolitano, Carmine Settembre, Otília V Vieira, Johannes M F G Aerts, Peace Atakpa-Adaji, Gemma Bruno, Antonella Capuozzo, Elvira De Leonibus, Chiara Di Malta, Cristina Escrevente, Alessandra Esposito, Paolo Grumati, Michael J Hall,
Opublikowane w: Traffic, Numer 5, 2022, ISSN 1398-9219
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/tra.12839

Zebrafish model as a screen to prevent cyst inflation in Autosomal Dominant Polycystic Kidney Disease (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Inês Oliveira, Raquel Jacinto, Sara Pestana, Fernando Nolasco, Joaquim Calado, Susana Santos Lopes, Mónica Roxo-Rosa
Opublikowane w: Int J Mol Sci, Numer 22/16, 2021, ISSN 1661-6596
Wydawca: MDPI
DOI: 10.3390/ijms22169013

Carbon monoxide and mitochondria – modulation of cell metabolism, redox response and cell death

Autorzy: Ana S. Almeida, Cláudia Figueiredo-Pereira, Helena L. A. Vieira
Opublikowane w: Frontiers in Physiology, Numer 6, 2015, ISSN 1664-042X
Wydawca: Frontiers Research Foundation

Carbon monoxide and the CNS: challenges and achievements

Autorzy: Cláudia S F Queiroga, Alessandro Vercelli, Helena L A Vieira
Opublikowane w: British Journal of Pharmacology, Numer 172/6, 2015, Strona(/y) 1533-1545, ISSN 0007-1188
Wydawca: Wiley-Blackwell
DOI: 10.1111/bph.12729

New method to assess mitophagy flux by flow cytometry

Autorzy: Marta Mauro-Lizcano, Lorena Esteban-Martínez, Esther Seco, Ana Serrano-Puebla, Lucia Garcia-Ledo, Cláudia Figueiredo-Pereira, Helena L A Vieira, Patricia Boya
Opublikowane w: Autophagy, Numer 11/5, 2015, Strona(/y) 833-843, ISSN 1554-8627
Wydawca: Landes Bioscience
DOI: 10.1080/15548627.2015.1034403

Rod disc renewal occurs by evagination of the ciliary plasma membrane that makes cadherin-based contacts with the inner segment

Autorzy: Thomas Burgoyne, Ingrid P. Meschede, Jemima J. Burden, Maryse Bailly, Miguel C. Seabra, Clare E. Futter
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 112/52, 2015, Strona(/y) 15922-15927, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1509285113

Effect of carbon monoxide on gene expression in cerebrocortical astrocytes: Validation of reference genes for quantitative real-time PCR

Autorzy: Sara R. Oliveira, Helena L.A. Vieira, Carlos B. Duarte
Opublikowane w: Nitric Oxide, Numer 49, 2015, Strona(/y) 80-89, ISSN 1089-8603
Wydawca: Academic Press
DOI: 10.1016/j.niox.2015.07.003

Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism - a role for Ca2+?

Autorzy: Sara R. Oliveira, Cláudia S. F. Queiroga, Helena L. A. Vieira
Opublikowane w: The Journal of Physiology, 2015, ISSN 0022-3751
Wydawca: Blackwell Publishing Inc.

Host cell autophagy contributes to Plasmodium liver development

Autorzy: Carolina Thieleke‐Matos, Mafalda Lopes da Silva, Laura Cabrita‐Santos, Martim D. Portal, Inês P. Rodrigues, Vanessa Zuzarte‐Luis, José S. Ramalho, Clare E. Futter, Maria M. Mota, Duarte C. Barral, Miguel C. Seabra
Opublikowane w: Cellular Microbiology, 2015, ISSN 1462-5814
Wydawca: Blackwell Publishing Inc.

Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).

Autorzy: Silène T. Wavre-Shapton, Alessandra A. Calvi, Mark Turmaine, Miguel C. Seabra, Daniel F. Cutler, Clare E. Futter, Hannah M. Mitchison
Opublikowane w: Human Molecular Genetics, 2015, ISSN 0964-6906
Wydawca: Oxford University Press

Rab27a GTPase modulates L-type Ca(2+) channel function via interaction with the II-III linker of CaV1.3 subunit.

Autorzy: Nadine Reichhart, Magdalena Markowski, Shimpei Ishiyama, Andrea Wagner, Sergio Crespo-Garcia, Talitha Schorb, José S. Ramalho, Vladimir M. Milenkovic, Renate Föckler, Miguel C. Seabra, Olaf Strauß
Opublikowane w: Cellular Signalling, 2015, ISSN 0898-6568
Wydawca: Elsevier BV

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

Autorzy: Margaret Alexander, Ruozhen Hu, Marah C. Runtsch, Dominique A. Kagele, Timothy L. Mosbruger, Tanya Tolmachova, Miguel C. Seabra, June L. Round, Diane M. Ward, Ryan M. O’Connell
Opublikowane w: Nature Communications, Numer 6/1, 2015, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms8321

Impact of the serum- and glucocorticoid-inducible kinase 1 on platelet dense granule biogenesis and secretion

Autorzy: B. Walker, E. Schmid, A. Russo, E.-M. Schmidt, O. Burk, P. Münzer, A. Velic, B. Macek, M. Schaller, M. Schwab, M. C. Seabra, M. Gawaz, F. Lang, O. Borst
Opublikowane w: Journal of Thrombosis and Haemostasis, Numer 13/7, 2015, Strona(/y) 1325-1334, ISSN 1538-7933
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jth.12998

Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL

Autorzy: T. Burgoyne, M. N. O'Connor, M. C. Seabra, D. F. Cutler, C. E. Futter
Opublikowane w: Journal of Cell Science, Numer 128/7, 2015, Strona(/y) 1400-1407, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.164400

Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease

Autorzy: Ana Silva, Luana Naia, Alejandro Dominguez, Márcio Ribeiro, Joana Rodrigues, Otília V. Vieira, Volkmar Lessmann, Ana Cristina Rego
Opublikowane w: Neurodegenerative Diseases, Numer 15/4, 2015, Strona(/y) 207-218, ISSN 1660-2854
Wydawca: S. Karger AG
DOI: 10.1159/000375447

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

Autorzy: Tania Martins-Marques, Steve Catarino, Monica Zuzarte, Carla Marques, Paulo Matafome, Paulo Pereira, Henrique Girão
Opublikowane w: Biochemical Journal, Numer 467/2, 2015, Strona(/y) 231-245, ISSN 0264-6021
Wydawca: Portland Press, Ltd.
DOI: 10.1042/BJ20141370

K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy

Autorzy: Joao Vasco Ferreira, Ana Rosa Soares, Jose Silva Ramalho, Paulo Pereira, Henrique Girao
Opublikowane w: Scientific Reports, Numer 5/1, 2015, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep10210

Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

Autorzy: Ana Rosa Soares, Tania Martins-Marques, Teresa Ribeiro-Rodrigues, Joao Vasco Ferreira, Steve Catarino, Maria João Pinho, Monica Zuzarte, Sandra Isabel Anjo, Bruno Manadas, Joost P.G. Sluijter, Paulo Pereira, Henrique Girao
Opublikowane w: Scientific Reports, Numer 5/1, 2015, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep13243

Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

Autorzy: Tania Martins-Marques, Sandra Isabel Anjo, Paulo Pereira, Bruno Manadas, Henrique Girão
Opublikowane w: Molecular & Cellular Proteomics, Numer 14/11, 2015, Strona(/y) 3040-3055, ISSN 1535-9476
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/mcp.M115.052894

Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs

Autorzy: Tânia Martins-Marques, Steve Catarino, Carla Marques, Paulo Matafome, Teresa Ribeiro-Rodrigues, Rui Baptista, Paulo Pereira, Henrique Girão
Opublikowane w: Biochimie, Numer 112, 2015, Strona(/y) 196-201, ISSN 0300-9084
Wydawca: Elsevier BV
DOI: 10.1016/j.biochi.2015.02.020

Connexin 43 ubiquitination determines the fate of gap junctions: restrict to survive

Autorzy: Teresa M. Ribeiro-Rodrigues, Steve Catarino, Maria J. Pinho, Paulo Pereira, Henrique Girao
Opublikowane w: Biochemical Society transactions, 2015, ISSN 0300-5127
Wydawca: Portland Press, Ltd.

To beat or not to beat: degradation of Cx43 imposes the heart rhythm

Autorzy: Tânia Martins-Marques, Steve Catarino, Carla Marques, Paulo Pereira, Henrique Girão
Opublikowane w: Biochemical Society transactions, 2015, ISSN 0300-5127
Wydawca: Portland Press, Ltd.

Autophagy and Ubiquitination in Cardiovascular Diseases

Autorzy: Tania Martins-Marques, Teresa Ribeiro-Rodrigues, Paulo Pereira, Patrice Codogno, Henrique Girao
Opublikowane w: DNA and Cell Biology, Numer 34/4, 2015, Strona(/y) 243-251, ISSN 1044-5498
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/dna.2014.2765

The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR

Autorzy: M. Roxo-Rosa, R. Jacinto, P. Sampaio, S. S. Lopes
Opublikowane w: Biology Open, Numer 4/11, 2015, Strona(/y) 1356-1366, ISSN 2046-6390
Wydawca: Company of Biologists Ltd
DOI: 10.1242/bio.014076

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

Autorzy: Quanlong Lu, Christine Insinna, Carolyn Ott, Jimmy Stauffer, Petra A. Pintado, Juliati Rahajeng, Ulrich Baxa, Vijay Walia, Adrian Cuenca, Yoo-Seok Hwang, Ira O. Daar, Susana Lopes, Jennifer Lippincott-Schwartz, Peter K. Jackson, Steve Caplan, Christopher J. Westlake
Opublikowane w: Nature Cell Biology, Numer 17/3, 2015, Strona(/y) 228-240, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/ncb3109

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Autorzy: Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter D Adams, Khosrow Adeli, Peter J Adhihetty, Sharon G Adler, Galila Agam, Rajesh Agarwal, Manish K Aghi, Maria Agnello, Patrizia Agostinis, Patricia V Aguilar, Julio Aguirre-Ghiso, Edoardo M Airoldi, Slimane Ait-Si-Ali, Takahiko Akematsu, Emmanuel
Opublikowane w: Autophagy, Numer 12/1, 2016, Strona(/y) 1-222, ISSN 1554-8627
Wydawca: Landes Bioscience
DOI: 10.1080/15548627.2015.1100356

Hippocampal neurogenesis response: What can we expect from two different models of hypertension?

Autorzy: Daniela Pedroso, Ana R. Nunes, Lucília N. Diogo, Carole Oudot, Emília C. Monteiro, Catherine Brenner, Helena L.A. Vieira
Opublikowane w: Brain Research, Numer 1646, 2016, Strona(/y) 199-206, ISSN 0006-8993
Wydawca: Elsevier BV
DOI: 10.1016/j.brainres.2016.05.044

Carbon monoxide improves neuronal differentiation and yield by increasing the functioning and number of mitochondria

Autorzy: Ana S. Almeida, Ursula Sonnewald, Paula M. Alves, Helena L.A. Vieira
Opublikowane w: Journal of Neurochemistry, Numer 138/3, 2016, Strona(/y) 423-435, ISSN 0022-3042
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jnc.13653

Carbon Monoxide Releasing Molecule-A1 (CORM-A1) Improves Neurogenesis: Increase of Neuronal Differentiation Yield by Preventing Cell Death

Autorzy: Ana S. Almeida, Nuno L. Soares, Melissa Vieira, Jan Bert Gramsbergen, Helena L. A. Vieira
Opublikowane w: PLOS ONE, Numer 11/5, 2016, Strona(/y) e0154781, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0154781

Arl13b and the exocyst interact synergistically in ciliogenesis

Autorzy: Cecília Seixas, Soo Young Choi, Noemi Polgar, Nicole L. Umberger, Michael P. East, Xiaofeng Zuo, Hugo Moreiras, Rania Ghossoub, Alexandre Benmerah, Richard A. Kahn, Ben Fogelgren, Tamara Caspary, Joshua H. Lipschutz, Duarte C. Barral
Opublikowane w: Molecular Biology of the Cell, Numer 27/2, 2016, Strona(/y) 308-320, ISSN 1059-1524
Wydawca: American Society for Cell Biology
DOI: 10.1091/mbc.E15-02-0061

shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity

Autorzy: Susana A. Gonçalves, Diana Macedo, Helena Raquel, Pedro D. Simões, Flaviano Giorgini, José S. Ramalho, Duarte C. Barral, Luís Ferreira Moita, Tiago Fleming Outeiro
Opublikowane w: PLOS Genetics, Numer 12/4, 2016, Strona(/y) e1005995, ISSN 1553-7390
Wydawca: Public Library of Science
DOI: 10.1371/journal.pgen.1005995

A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair

Autorzy: Marisa Encarnação, Lília Espada, Cristina Escrevente, Denisa Mateus, José Ramalho, Xavier Michelet, Inês Santarino, Victor W. Hsu, Michael B. Brenner, Duarte C. Barral, Otília V. Vieira
Opublikowane w: The Journal of Cell Biology, Numer 213/6, 2016, Strona(/y) 631-640, ISSN 0021-9525
Wydawca: Rockefeller University Press
DOI: 10.1083/jcb.201511093

Arf proteins in cancer cell migration

Autorzy: Cristina Casalou, Alexandra Faustino, Duarte C. Barral
Opublikowane w: Small GTPases, Numer 7/4, 2016, Strona(/y) 270-282, ISSN 2154-1248
Wydawca: Landes Bioscience
DOI: 10.1080/21541248.2016.1228792

Visual Acuity after Retinal Gene Therapy for Choroideremia

Autorzy: Thomas L. Edwards, Jasleen K. Jolly, Markus Groppe, Alun R. Barnard, Charles L. Cottriall, Tanya Tolmachova, Graeme C. Black, Andrew R. Webster, Andrew J. Lotery, Graham E. Holder, Kanmin Xue, Susan M. Downes, Matthew P. Simunovic, Miguel C. Seabra, Robert E. MacLaren
Opublikowane w: New England Journal of Medicine, Numer 374/20, 2016, Strona(/y) 1996-1998, ISSN 0028-4793
Wydawca: Massachusetts Medical Society
DOI: 10.1056/NEJMc1509501

Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

Autorzy: Bret Wankel, Jiangyong Ouyang, Xuemei Guo, Krassimira Hadjiolova, Jeremy Miller, Yi Liao, Daniel Kai Long Tham, Rok Romih, Leonardo R. Andrade, Iwona Gumper, Jean-Pierre Simon, Rakhee Sachdeva, Tanya Tolmachova, Miguel C. Seabra, Mitsunori Fukuda, Nicole Schaeren-Wiemers, Wan Jin Hong, David D. Sabatini, Xue-Ru Wu, Xiangpeng Kong, Gert Kreibich, Michael J. Rindler, Tung-Tien Sun
Opublikowane w: Molecular Biology of the Cell, Numer 27/10, 2016, Strona(/y) 1621-1634, ISSN 1059-1524
Wydawca: American Society for Cell Biology
DOI: 10.1091/mbc.E15-04-0230

In vitro activity of quaternary ammonium surfactants against streptococcal, chlamydial, and gonococcal infective agents

Autorzy: Ângela S. Inácio, Alexandra Nunes, Catarina Milho, Luís Jaime Mota, Maria J. Borrego, João P. Gomes, Winchil L. C. Vaz, Otília V. Vieira
Opublikowane w: Antimicrobial agents and chemotherapy, 2016, ISSN 0066-4804
Wydawca: American Society for Microbiology

Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis

Autorzy: Ângela S. Inácio, Neuza S. Domingues, Alexandra Nunes, Patrícia T. Martins, Maria J. Moreno, Luís M. Estronca, Rui Fernandes, António J. M. Moreno, Maria J. Borrego, João P. Gomes, Winchil L. C. Vaz, Otília V. Vieira
Opublikowane w: Journal of Antimicrobial Chemotherapy, Numer 71/3, 2016, Strona(/y) 641-654, ISSN 0305-7453
Wydawca: Oxford University Press
DOI: 10.1093/jac/dkv405

Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin

Autorzy: Tania Martins-Marques, Maria Joao Pinho, Monica Zuzarte, Carla Oliveira, Paulo Pereira, Joost P. G. Sluijter, Celia Gomes, Henrique Girao
Opublikowane w: Journal of Extracellular Vesicles, Numer 5/1, 2016, Strona(/y) 32538, ISSN 2001-3078
Wydawca: Taylor & Francis
DOI: 10.3402/jev.v5.32538

Accelerated age-related olfactory decline among type 1 Usher patients

Autorzy: João Carlos Ribeiro, Bárbara Oliveiros, Paulo Pereira, Natália António, Thomas Hummel, António Paiva, Eduardo D. Silva
Opublikowane w: Scientific Reports, Numer 6/1, 2016, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep28309

Three-dimensional flow in Kupffer’s Vesicle

Autorzy: T. D. Montenegro-Johnson, D. I. Baker, D. J. Smith, S. S. Lopes
Opublikowane w: Journal of Mathematical Biology, Numer 73/3, 2016, Strona(/y) 705-725, ISSN 0303-6812
Wydawca: Springer Verlag
DOI: 10.1007/s00285-016-0967-7

Report of the 4th European Zebrafish Principal Investigator Meeting

Autorzy: Susana S. Lopes, Martin Distel, Claudia Linker, Rita Fior, Rui Monteiro, Isaac H. Bianco, Ruben Portugues, Uwe Strähle, Leonor Saúde
Opublikowane w: Zebrafish, Numer 13/6, 2016, Strona(/y) 590-595, ISSN 1545-8547
Wydawca: Mary Ann Liebert Inc.
DOI: 10.1089/zeb.2016.1364

Role of Cell Metabolism and Mitochondrial Function During Adult Neurogenesis

Autorzy: Ana S. Almeida, Helena L. A. Vieira
Opublikowane w: Neurochemical Research, Numer 42/6, 2017, Strona(/y) 1787-1794, ISSN 0364-3190
Wydawca: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11064-016-2150-3

Mitochondrion: a common organelle for distinct cell deaths?

Autorzy: Z. Wang, C. Figueiredo-Pereira, C. Oudot, H.L.A. Vieira, C. Brenner
Opublikowane w: International review of cell and molecular biology, 2017, ISSN 1937-6448
Wydawca: Elsevier BV

Carbon monoxide reverses the metabolic adaptation of microglia cells to an inflammatory stimulus

Autorzy: Jayne Louise Wilson, Frédéric Bouillaud, Ana S. Almeida, Helena L. Vieira, Mohand Ouidir Ouidja, Jean-Luc Dubois-Randé, Roberta Foresti, Roberto Motterlini
Opublikowane w: Free Radical Biology and Medicine, Numer 104, 2017, Strona(/y) 311-323, ISSN 0891-5849
Wydawca: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.01.022

Commensal-to-pathogen transition: One-single transposon insertion results in two pathoadaptive traits in Escherichia coli -macrophage interaction

Autorzy: João T. Proença, Duarte C. Barral, Isabel Gordo
Opublikowane w: Scientific Reports, Numer 7/1, 2017, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-017-04081-1

Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli

Autorzy: Margaret Alexander, Andrew G. Ramstead, Kaylyn M. Bauer, Soh-Hyun Lee, Marah C. Runtsch, Jared Wallace, Thomas B. Huffaker, Dane K. Larsen, Tanya Tolmachova, Miguel C. Seabra, June L. Round, Diane M. Ward, Ryan M. O’Connell
Opublikowane w: The Journal of Immunology, Numer 199/10, 2017, Strona(/y) 3559-3570, ISSN 0022-1767
Wydawca: American Association of Immunologists
DOI: 10.4049/jimmunol.1700904

Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis

Autorzy: Inês B. Santarino, Michelle S. Viegas, Neuza S. Domingues, Ana M. Ribeiro, Miguel P. Soares, Otília V. Vieira
Opublikowane w: Scientific Reports, Numer 7/1, 2017, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-017-05687-1

Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages

Autorzy: Inês B. Santarino, Otília V. Vieira
Opublikowane w: FEBS Open Bio, Numer 7/9, 2017, Strona(/y) 1281-1290, ISSN 2211-5463
Wydawca: Elsevier BV
DOI: 10.1002/2211-5463.12262

Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages

Autorzy: Neuza Domingues, Luís M.B.B. Estronca, João Silva, Marisa R. Encarnação, Rita Mateus, Diogo Silva, Inês B. Santarino, Margarida Saraiva, Maria I.L. Soares, Teresa M.V.D. Pinho e Melo, António Jacinto, Winchil L.C. Vaz, Otília V. Vieira
Opublikowane w: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Numer 1862/2, 2017, Strona(/y) 210-220, ISSN 1388-1981
Wydawca: Elsevier BV
DOI: 10.1016/j.bbalip.2016.10.009

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis

Autorzy: Teresa M. Ribeiro-Rodrigues, Tiago L. Laundos, Rita Pereira-Carvalho, Daniela Batista-Almeida, Ricardo Pereira, Vanessa Coelho-Santos, Ana P. Silva, Rosa Fernandes, Monica Zuzarte, Francisco J. Enguita, Marina C. Costa, Perpetua Pinto-do-Ó, Marta T. Pinto, Pedro Gouveia, Lino Ferreira, Justin C. Mason, Paulo Pereira, Brenda R. Kwak, Diana S. Nascimento, Henrique Girão
Opublikowane w: Cardiovascular Research, Numer 113/11, 2017, Strona(/y) 1338-1350, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvx118

Molecular control of chaperone-mediated autophagy

Autorzy: Steve Catarino, Paulo Pereira, Henrique Girão
Opublikowane w: Essays In Biochemistry, Numer 61/6, 2017, Strona(/y) 663-674, ISSN 0071-1365
Wydawca: Portland Press, Ltd.
DOI: 10.1042/EBC20170057

Hyperglycemia-induced degradation of HIF-1α contributes to impaired response of cardiomyocytes to hypoxia

Autorzy: Ana Rita Ramalho, Adriana Toscano, Paulo Pereira, Henrique Girão, Lino Gonçalves, Carla Marques
Opublikowane w: Revista Portuguesa de Cardiologia, Numer 36/5, 2017, Strona(/y) 367-373, ISSN 0870-2551
Wydawca: Sociedade Portuguesa De Cardiologia
DOI: 10.1016/j.repc.2016.09.018

Elucidation of the dynamic nature of interactome networks: A practical tutorial

Autorzy: Sandra I. Anjo, Tania Martins-Marques, Paulo Pereira, Henrique Girão, Bruno Manadas
Opublikowane w: Journal of Proteomics, Numer 171, 2018, Strona(/y) 116-126, ISSN 1874-3919
Wydawca: Elsevier BV
DOI: 10.1016/j.jprot.2017.04.011

Bin1 and CD2AP polarise the endocytic generation of beta‐amyloid

Autorzy: Florent Ubelmann, Tatiana Burrinha, Laura Salavessa, Ricardo Gomes, Cláudio Ferreira, Nuno Moreno, Cláudia Guimas Almeida
Opublikowane w: EMBO reports, Numer 18/1, 2017, Strona(/y) 102-122, ISSN 1469-221X
Wydawca: Nature Publishing Group
DOI: 10.15252/embr.201642738

A Novel Protocol to Quantitatively Measure the Endocytic Trafficking of Amyloid Precursor Protein (APP) in Polarized Primary Neurons with Sub-cellular Resolution

Autorzy: Florent Ubelmann, Tatiana Burrinha, Cláudia Guimas Almeida
Opublikowane w: BIO-PROTOCOL, Numer 7/23, 2017, ISSN 2331-8325
Wydawca: Bio-protocol LLC
DOI: 10.21769/BioProtoc.2629

Measuring the Endocytic Recycling of Amyloid Precursor Protein (APP) in Neuro2a Cells

Autorzy: Florent Ubelmann, Tatiana Burrinha, Cláudia Guimas Almeida
Opublikowane w: BIO-PROTOCOL, Numer 7/23, 2017, ISSN 2331-8325
Wydawca: Bio-protocol LLC
DOI: 10.21769/BioProtoc.2635

Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations

Autorzy: Rita Gorgulho, Raquel Jacinto, Susana S. Lopes, Sofia A. Pereira, Erin M. Tranfield, Gabriel G. Martins, Emilio J. Gualda, Rico J. E. Derks, Ana C. Correia, Evelyne Steenvoorden, Petra Pintado, Oleg A. Mayboroda, Emilia C. Monteiro, Judit Morello
Opublikowane w: Archives of Toxicology, Numer 92/1, 2018, Strona(/y) 411-423, ISSN 0340-5761
Wydawca: Springer Verlag
DOI: 10.1007/s00204-017-2063-1

Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxj1a in zebrafish left-right organizer

Autorzy: Barbara Tavares, Raquel Jacinto, Pedro Sampaio, Sara Pestana, Andreia Pinto, Andreia Vaz, Mónica Roxo-Rosa, Rui Gardner, Telma Lopes, Britta Schilling, Ian Henry, Leonor Saúde, Susana Santos Lopes
Opublikowane w: eLife, Numer 6, 2017, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/eLife.25165

Dynamics of cilia length in left–right development

Autorzy: P. Pintado, P. Sampaio, B. Tavares, T. D. Montenegro-Johnson, D. J. Smith, S. S. Lopes
Opublikowane w: Royal Society Open Science, Numer 4/3, 2017, Strona(/y) 161102, ISSN 2054-5703
Wydawca: Royal Society Publishing
DOI: 10.1098/rsos.161102

Pure Polyphenols Applications for Cardiac Health and Disease

Autorzy: Claudia N. Santos, Andreia Gomes, Carole Oudot, Daniela Dias-Pedroso, Ana Rodriguez-Mateos, Helena L.A. Vieira, Catherine Brenner
Opublikowane w: Current Pharmaceutical Design, Numer 24/19, 2018, Strona(/y) 2137-2156, ISSN 1381-6128
Wydawca: Bentham Science Publishers
DOI: 10.2174/1381612824666180608102344

Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells

Autorzy: Nanna Dreyer-Andersen, Ana Sofia Almeida, Pia Jensen, Morad Kamand, Justyna Okarmus, Tine Rosenberg, Stig Düring Friis, Alberto Martínez Serrano, Morten Blaabjerg, Bjarne Winther Kristensen, Troels Skrydstrup, Jan Bert Gramsbergen, Helena L. A. Vieira, Morten Meyer
Opublikowane w: PLOS ONE, Numer 13/1, 2018, Strona(/y) e0191207, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0191207

Improvement of neuronal differentiation by carbon monoxide: Role of pentose phosphate pathway

Autorzy: Ana S. Almeida, Nuno L. Soares, Catarina O. Sequeira, Sofia A. Pereira, Ursula Sonnewald, Helena L.A. Vieira
Opublikowane w: Redox Biology, Numer 17, 2018, Strona(/y) 338-347, ISSN 2213-2317
Wydawca: Elsevier BV
DOI: 10.1016/j.redox.2018.05.004

P2X7 Receptors Mediate CO-Induced Alterations in Gene Expression in Cultured Cortical Astrocytes—Transcriptomic Study

Autorzy: Sara R. Oliveira, Cláudia Figueiredo-Pereira, Carlos B. Duarte, Helena L. A. Vieira
Opublikowane w: Molecular Neurobiology, 2018, ISSN 0893-7648
Wydawca: Humana Press, Inc.
DOI: 10.1007/s12035-018-1302-7

Phenolic Metabolites Modulate Cardiomyocyte Beating in Response to Isoproterenol

Autorzy: Daniela Dias-Pedroso, Joel Guerra, Andreia Gomes, Carole Oudot, Catherine Brenner, Cláudia N. Santos, Helena L. A. Vieira
Opublikowane w: Cardiovascular Toxicology, 2018, ISSN 1530-7905
Wydawca: Humana Press, Inc.
DOI: 10.1007/s12012-018-9485-8

Melanin Transferred to Keratinocytes Resides in Nondegradative Endocytic Compartments

Autorzy: Maria S. Correia, Hugo Moreiras, Francisco J.C. Pereira, Matilde V. Neto, Tiago C. Festas, Abul K. Tarafder, José S. Ramalho, Miguel C. Seabra, Duarte C. Barral
Opublikowane w: Journal of Investigative Dermatology, Numer 138/3, 2018, Strona(/y) 637-646, ISSN 0022-202X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.09.042

Rab GTPase regulation of bacteria and protozoa phagocytosis occurs through the modulation of phagocytic receptor surface expression

Autorzy: Elsa Seixas, Cristina Escrevente, Miguel C. Seabra, Duarte C. Barral
Opublikowane w: Scientific Reports, Numer 8/1, 2018, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-018-31171-5

Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

Autorzy: Kanmin Xue, Jasleen K Jolly, Alun R. Barnard, Anna Rudenko, Anna P. Salvetti, Maria I. Patrício, Thomas L. Edwards, Markus Groppe, Harry O. Orlans, Tanya Tolmachova, Graeme C. Black, Andrew R. Webster, Andrew J. Lotery, Graham E. Holder, Susan M. Downes, Miguel C. Seabra, Robert E. MacLaren
Opublikowane w: Nature Medicine, Numer 24/10, 2018, Strona(/y) 1507-1512, ISSN 1078-8956
Wydawca: Nature Publishing Group
DOI: 10.1038/s41591-018-0185-5

Two-Year Results After AAV2-Mediated Gene Therapy for Choroideremia: The Alberta Experience

Autorzy: Ioannis S. Dimopoulos, Stephanie C. Hoang, Alina Radziwon, Natalia M. Binczyk, Miguel C. Seabra, Robert E. MacLaren, Rizwan Somani, Matthew T.S. Tennant, Ian M. MacDonald
Opublikowane w: American Journal of Ophthalmology, Numer 193, 2018, Strona(/y) 130-142, ISSN 0002-9394
Wydawca: Elsevier BV
DOI: 10.1016/j.ajo.2018.06.011

Rab3a and Rab10 are regulators of lysosome exocytosis and plasma membrane repair

Autorzy: Otilia V. Vieira
Opublikowane w: Small GTPases, Numer 9/4, 2016, Strona(/y) 349-351, ISSN 2154-1248
Wydawca: Landes Bioscience
DOI: 10.1080/21541248.2016.1235004

Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis

Autorzy: Mark S. Gibson, Neuza Domingues, Otilia V. Vieira
Opublikowane w: Frontiers in Physiology, Numer 9, 2018, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2018.00654

Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients

Autorzy: Mathias J. Gerl, Winchil L. C. Vaz, Neuza Domingues, Christian Klose, Michal A. Surma, Júlio L. Sampaio, Manuel S. Almeida, Gustavo Rodrigues, Pedro Araújo-Gonçalves, Jorge Ferreira, Claudia Borbinha, João Pedro Marto, Miguel Viana-Baptista, Kai Simons, Otilia V. Vieira
Opublikowane w: Scientific Reports, Numer 8/1, 2018, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-018-33116-4

MicroRNA-424(322) as a new marker of disease progression in pulmonary arterial hypertension and its role in right ventricular hypertrophy by targeting SMURF1

Autorzy: Rui Baptista, Carla Marques, Steve Catarino, Francisco J Enguita, Marina C Costa, Paulo Matafome, Mónica Zuzarte, Graça Castro, Abílio Reis, Pedro Monteiro, Mariano Pêgo, Paulo Pereira, Henrique Girão
Opublikowane w: Cardiovascular Research, Numer 114/1, 2017, Strona(/y) 53-64, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvx187

The Endolysosomal System and Proteostasis: From Development to Degeneration

Autorzy: Bettina Winckler, Victor Faundez, Sandra Maday, Qian Cai, Cláudia Guimas Almeida, Huaye Zhang
Opublikowane w: The Journal of Neuroscience, Numer 38/44, 2018, Strona(/y) 9364-9374, ISSN 0270-6474
Wydawca: Society for Neuroscience
DOI: 10.1523/JNEUROSCI.1665-18.2018

Impact of late-onset Alzheimer’s genetic risk factors on beta-amyloid endocytic production

Autorzy: Cláudia Guimas Almeida, Farzaneh Sadat Mirfakhar, Catarina Perdigão, Tatiana Burrinha
Opublikowane w: Cellular and Molecular Life Sciences, Numer 75/14, 2018, Strona(/y) 2577-2589, ISSN 1420-682X
Wydawca: Birkhauser Verlag
DOI: 10.1007/s00018-018-2825-9

Wall stress enhanced exocytosis of extracellular vesicles as a possible mechanism of left-right symmetry-breaking in vertebrate development

Autorzy: J. Solowiej-Wedderburn, D.J. Smith, S.S. Lopes, T.D. Montenegro-Johnson
Opublikowane w: Journal of Theoretical Biology, Numer 460, 2019, Strona(/y) 220-226, ISSN 0022-5193
Wydawca: Academic Press
DOI: 10.1016/j.jtbi.2018.10.015

Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury

Autorzy: Judit Morello, Rico J. E. Derks, Susana S. Lopes, Evelyne Steenvoorden, Emilia C. Monteiro, Oleg A. Mayboroda, Sofia A. Pereira
Opublikowane w: Frontiers in Pharmacology, Numer 9, 2018, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2018.01193

Arl13b Regulates Breast Cancer Cell Migration and Invasion by Controlling Integrin-Mediated Signaling

Autorzy: Cristina Casalou, Alexandra Faustino, Fernanda Silva, Inês C. Ferreira, Daniela Vaqueirinho, Andreia Ferreira, Pedro Castanheira, Teresa Barona, José S. Ramalho, Jacinta Serpa, Ana Félix, Duarte C. Barral
Opublikowane w: Cancers, Numer 11/10, 2019, Strona(/y) 1461, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101461

Melanin processing by keratinocytes: A non‐microbial type of host‐pathogen interaction?

Autorzy: Hugo Moreiras, Mafalda Lopes‐da‐Silva, Miguel C. Seabra, Duarte C. Barral
Opublikowane w: Traffic, Numer 20/4, 2019, Strona(/y) 301-304, ISSN 1398-9219
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/tra.12638

Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a

Autorzy: Paolo Sanzà, Richard D. Evans, Deborah A. Briggs, Marta Cantero, Lluis Montoliu, Shyamal Patel, Elena V. Sviderskaya, Aymelt Itzen, Ana C. Figueiredo, Miguel C. Seabra, Alistair N. Hume
Opublikowane w: Journal of Cell Science, Numer 132/9, 2019, Strona(/y) jcs212035, ISSN 0021-9533
Wydawca: The Company of Biologists Ltd.
DOI: 10.1242/jcs.212035

Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease

Autorzy: Matthew J. Hayes, Thomas Burgoyne, Silene T. Wavre-Shapton, Tanya Tolmachova, Miguel C. Seabra, Clare E. Futter
Opublikowane w: Investigative Opthalmology & Visual Science, Numer 60/7, 2019, Strona(/y) 2515, ISSN 1552-5783
Wydawca: Invest Ophthalmol Vis Sci
DOI: 10.1167/iovs.19-26784

Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics

Autorzy: Elisabeth M. Storck, Julia Morales-Sanfrutos, Remigiusz A. Serwa, Nattawadee Panyain, Thomas Lanyon-Hogg, Tanya Tolmachova, Leandro N. Ventimiglia, Juan Martin-Serrano, Miguel C. Seabra, Beata Wojciak-Stothard, Edward W. Tate
Opublikowane w: Nature Chemistry, Numer 11/6, 2019, Strona(/y) 552-561, ISSN 1755-4330
Wydawca: Nature Publishing Group
DOI: 10.1038/s41557-019-0237-6

Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis

Autorzy: Martin D. Burkhalter, Arthi Sridhar, Pedro Sampaio, Raquel Jacinto, Martina S. Burczyk, Cornelia Donow, Max Angenendt, Maja Hempel, Paul Walther, Petra Pennekamp, Heymut Omran, Susana S. Lopes, Stephanie M. Ware, Melanie Philipp
Opublikowane w: Journal of Clinical Investigation, Numer 129/7, 2019, Strona(/y) 2841-2855, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci98890

Crosstalk between cilia and autophagy: implication for human diseases (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: Manuela Morleo, Helena L A Vieira, Petra Pennekamp, Alessandro Palma, Liliana Bento-Lopes, Heymut Omran, Susana S Lopes, Duarte C Barral, Brunella Franco
Opublikowane w: Autophagy, Numer 1/20, 2022, ISSN 1554-8627
Wydawca: Landes Bioscience
DOI: 10.1080/15548627.2022.2067383

Lysosome (dys)function in atherosclerosis – a big weight on the shoulders of a small organelle (project related publication after the start date of LYSOCIL project, RP2)

Autorzy: André R A Marques, Cristiano Ramos, Gisela Machado-Oliveira, Otília V Vieira
Opublikowane w: Front Cell Dev Biol, 2021, ISSN 2296-634X
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.658995

Assessment of Mitochondrial Protein Glutathionylation as Signaling for CO Pathway

Autorzy: Ana S. Almeida, Helena L. A. Vieira
Opublikowane w: Mitochondrial Medicine, Numer 1264, 2015, Strona(/y) 343-350, ISBN 978-1-4939-2256-7
Wydawca: Springer New York
DOI: 10.1007/978-1-4939-2257-4_30

Wyszukiwanie danych OpenAIRE...

Rezultaty

Publikacje

Udostępnij tę stronę

Pobierz