Rezultaty
Presentation of scientific data in peerreviewed manuscript
PhD Theses (WP2)Five PhD Theses
Report on network school 1 (NS1)Report will be produced after the network school 1, indicating the activities and summaries of the different lectures/laboratory activities.
Characterization of cortical excitation/inhibition imbalance in vivo in models of synaptic dysfunction using mesoscopic methodsPresentation of scientific data in peerreviewed manuscript
PhD Theses (WP1)Three PhD Theses
Identification of the role of the excitation/inhibition (E/I) imbalance in the cortico-thalamic system in the development of neuropsychiatric disordersPresentation of scientific data in peerreviewed manuscript
Report on network school 2 (NS2)Report will be produced after the network school 2 indicating the activities and summaries of the different lectureslaboratory activities
Identification of presynaptic defects and alterations in glutamate receptor dynamics in Fragile X syndromePresentation of scientific data in peerreviewed manuscript
Oral/ Poster presentations in international scientific meetings (WP3)Presentation of scientific data in a scientific meetings as oral communications b scientific meetings as poster presentations
Identification of circuit deficits associated with ASDPresentation of scientific data in peerreviewed manuscript
Development and characterization of human-derived neurons and brain organoids as models of neurodevelopmental disordersPresentation of scientific data in peerreviewed manuscript
Establishment of the impact of the corticotropic releasing hormone system on schizophrenia- and ASD-related endophenotypePresentation of scientific data in peerreviewed manuscript
Oral/ Poster presentations in international scientific meetings (WP2)Presentation of scientific data in a scientific meetings as oral communications b scientific meetings as poster presentations
Identification of the role of specific mitochondrial genes for the development of psychopathologiesPresentation of scientific data in peerreviewed manuscript
Depiction of synapses and functional networks in a new paradigm to model Down syndrome (human iPSC-derived neurons from DS donors transplanted in the mouse brain)Presentation of scientific data in peerreviewed manuscript
Report on network school 3 (NS3)Report will be produced after the network school 3 indicating the activities and summaries of the different lectureslaboratory activities
Public media disseminationWe expect that several deliverables will be produced based on press reports focusing on particular aspects of the Syn2Psy research programme. We expect that media outlets will pick up the press releases and perform media articles, including interviews with involved scientists and ESRs.
Definition of the therapeutic potential of the endocannabinoid system in an ASD modelPresentation of scientific data in peerreviewed manuscript
Report on outreach & public engagementA final outreach report containing a description of all outreach initiatives with feedback from the public appropriate metrics photos and adicional videos will be prepared by month 48
Report on network school 4 (NS4)Report will be produced after the network school 4 indicating the activities and summaries of the different lectureslaboratory activities
Identification of defects in single NMDA receptor dynamics in psychosisPresentation of scientific data in peerreviewed manuscript
Oral/ Poster presentations in international scientific meetings (WP1)Presentation of scientific data in a scientific meetings as oral communications b scientific meetings as poster presentations
Establishment of the role of stargazin in psychiatric disorders; development of targeted therapiesPresentation of scientific data in a peerreviewed manuscript
Identification of aberrant synaptic mRNA translation as a point of convergence for multiple genetic causes of ASD/IDPresentation of scientific data in peerreviewed manuscript
PhD Theses (WP3)Five PhD Theses
Theatre play written and interpreted by the ESRs in collaboration with the Marionet theatre company.
Final ConferenceFinal project conference.
A public website will be prepared, open to the general public and demonstrating the general activities of the consortium, plus scientific data originating from the programme, biographies from the involved reserachers, important links, etc.
Publikacje
Autorzy:
Ágata Silván, Kristi Anne Kohlmeier, Kjartan Frisch Herrik, Charlotte Hougaard
Opublikowane w:
Synapse, 2023, ISSN 1098-2396
Wydawca:
Wiley Periodicals, LLC.
DOI:
10.1002/syn.22283
Autorzy:
Ana Rafaela Oliveira, Solange Martins, Giuseppe Cammarata, Mariana Martins,
Ana Maria Cardoso, Maria Rosário Almeida, Maria do Carmo Macário, Isabel Santana, João Peça and Ana Luísa Cardoso.
Opublikowane w:
Biomedicines, 2022, ISSN 2227-9059
Wydawca:
MDPI
DOI:
10.3390/biomedicines10081905
Autorzy:
Daniel Hunter, Zoe Jamet, Laurent Groc
Opublikowane w:
Neurobiology of Disease, Numer 147, 2021, Strona(/y) 105161, ISSN 0969-9961
Wydawca:
Academic Press
DOI:
10.1016/j.nbd.2020.105161
Autorzy:
Elisa Corti, Carlos B. Duarte.
Opublikowane w:
Biochemical Society Transactions, 2023, ISSN 1470-8752
Wydawca:
Portland Press, Ltd.
DOI:
10.1042/bst20220827
Autorzy:
Sriparna Ghosal, Elias Gebara, Eva Ramos-Fernández, Alessandro Chioino, Jocelyn Grosse , Isabelle Guillot de Suduiraut, Olivia Zanoletti, Bernard Schneider, Antonio Zorzano, Simone Astori, Carmen Sandi.
Opublikowane w:
Cell Reports, 2023, ISSN 2211-1247
Wydawca:
Cell Press
DOI:
10.1016/j.celrep.2023.112776
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