Host directed medicine in invasive fungal infection

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Report on journalistic and scientific immunotherapy narratives

An analysis will be performed of the Englishlanguage journalistic and scientific discourse surrounding immunotherapy for infections

Development of project website and project visual identity

Development of a project website and of a logo that visually identifies the project and allow people to recognise the HDMFUN message at the first glance

Publikacje

Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study

Autorzy: Simon Feys, MD Samuel M Gonçalves, MSc * Mona Khan, PhD * Sumin Choi, MSc * Bram Boeckx, PhD Denis Chatelain, MD Cristina Cunha, PhD Yves Debaveye, MD Prof Greet Hermans, MD Marjan Hertoghs, MD Steph
Opublikowane w: The Lancet Respiratory Medicine, Numer monthly, 2022, Strona(/y) P1147-1159
Wydawca: Elsevier
DOI: 10.1016/s2213-2600(22)00259-4

Enteric delivery of indole-3-carboxylic acid unlocks therapeutic potential of postbiotic metabolite cascade

Autorzy: Matteo Puccetti, Marilena Pariano, Claudia Stincardini, Consuelo Fabi, Roberta Galarini, Carolina Barola, Husam Br. Alabed, Dorotea Frongia Mancini, Roberto Maria Pellegrino, Enrico Garaci, Maurizio Ricci, Luigina Romani, Stefano Giovagnoli
Opublikowane w: International Journal of Pharmaceutics, Numer 684, 2025, Strona(/y) 126158, ISSN 0378-5173
Wydawca: Elsevier BV
DOI: 10.1016/j.ijpharm.2025.126158

Rapidly expanded partially HLA DRB1–matched fungus-specific T cells mediate in vitro and in vivo antifungal activity

Autorzy: Gloria Castellano-González, Helen M. McGuire, Fabio Luciani, Leighton E. Clancy, Ziduo Li, Selmir Avdic, Brendan Hughes, Mandeep Singh, Barbara Fazekas de St Groth, Giorgia Renga, Marilena Pariano, Marina M. Bellet, Luigina Romani, David J. Gottlieb
Opublikowane w: Blood Advances, Numer 4/14, 2020, Strona(/y) 3443-3456, ISSN 2473-9529
Wydawca: Europe PMC
DOI: 10.1182/bloodadvances.2020001565

Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway

Autorzy: Jia, Lei-Jie; Rafiq, Muhammad; Radosa, Lukáš; Hortschansky, Peter; Cunha, Cristina; Cseresnyés, Zoltán; Krüger, Thomas; Schmidt, Franziska; Heinekamp, Thorsten; Straßburger, Maria; Löffler, Bettina; Doenst, Torsten; Lacerda, João; Campos, António; Figge, Marc Thilo; Carvalho, Agostinho; Kniemeyer, Olaf; Brakhage, Axel A.
Opublikowane w: Cell Host Microb, Numer 31 (3), 2023, Strona(/y) 16, ISSN 1934-6069
Wydawca: Cell Press
DOI: 10.1016/j.chom.2023.02.002

Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation

Autorzy: da Silva-Ferreira S, Duarte-Oliveira C, Antunes D, Barbosa-Matos C, Mendes-Frias A, Torrado E, Costa S, Silvestre R, Cunha C, Carvalho A
Opublikowane w: Frontiers in Cellular and Infection Microbiology, Numer 12, 2022, Strona(/y) 1005839, ISSN 2235-2988
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.1005839

Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

Autorzy: Jose Manuel Sánchez-Maldonado, Ana Moñiz-Díez, Rob ter Horst, Daniele Campa, Antonio José Cabrera-Serrano, Manuel Martínez-Bueno, María del Pilar Garrido-Collado, Francisca Hernández-Mohedo, Laura Fernández-Puerta, Miguel Ángel López-Nevot, Cristina Cunha, Pedro Antonio González-Sierra, Jan Springer, Michaela Lackner, Laura Alcazar-Fuoli, Luana Fianchi, José María Aguado, Livio Pagano
Opublikowane w: Journal of Fungi, Numer 7/1, 2021, Strona(/y) 4, ISSN 2309-608X
Wydawca: -
DOI: 10.3390/jof7010004

Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study.

Autorzy: Feys S, Vanmassenhove S, Kraisin S, Yu K, Jacobs C, Boeckx B, Cambier S, Cunha C, Debaveye Y, Gonçalves SM, Hermans G, Humblet-Baron S, Jansen S, Lagrou K, Meersseman P, Neyts J, Peetermans M, Rocha-
Opublikowane w: The Lancet Microbe., Numer 5(3), 2024, Strona(/y) e247-e260.
Wydawca: Elsevier Ltd.
DOI: 10.1016/s2666-5247(23)00368-3

Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches.

Autorzy: Claudio Costantini, Marilena Pariano, Matteo Puccetti, Stefano Giovagnoli , Gioena Pampalone , Mirco Dindo , Barbara Cellini , Luigina Romani.
Opublikowane w: Front Mol Biosci, Numer 11, 2024, Strona(/y) 1386598, ISSN 1746-2665
Wydawca: Frontiers
DOI: 10.3389/fmolb.2024.1386598

The Microbiota/Host Immune System Interaction in the Nose to Protect from COVID-19

Autorzy: Arianna Di Stadio, Claudio Costantini, Giorgia Renga, Marilena Pariano, Giampietro Ricci, Luigina Romani
Opublikowane w: Life, Numer 10/12, 2020, Strona(/y) 345, ISSN 2075-1729
Wydawca: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life10120345

Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus

Autorzy: Daniela Antunes; Samuel M. Gonçalves; Vasiliki Matzaraki; Cláudia S. Rodrigues; Relber A. Gonçales; Joana Rocha; Jorge Sáiz; António Marques; Egídio Torrado; Ricardo Silvestre; Fernando Rodrigue
Opublikowane w: Microbiol Spectr, Numer 11(1), 2023, Strona(/y) e0225622
Wydawca: American Society for Microbiology,
DOI: 10.1128/spectrum.02256-22

Aspergillus fumigatus and aspergillosis: From basics to clinics

Autorzy: Arastehfar A, Carvalho A, Houbraken J, Lombardi L, Garcia-Rubio R, Jenks JD, Rivero-Menendez O, Aljohani R, Jacobsen ID, Berman J, Osherov N, Hedayati MT, Ilkit M, Armstrong-James D, Gabaldón T, Mele
Opublikowane w: Studies in Mycology, Numer May 10;100, 2021, Strona(/y) 100115
Wydawca: Westerdijk Fungal Biodiversity Institute
DOI: 10.1016/j.simyco.2021.100115

The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries

Autorzy: Hoenigl M, Seidel D, Carvalho A, Rudramurthy SM, Arastehfar A, Gangneux JP, Nasir N, Bonifaz A, Araiza J, Klimko N, Serris A, Lagrou K, Meis JF, Cornely OA, Perfect JR, White PL, Chakrabarti A
Opublikowane w: Lancet Microbe, Numer Jul;3(7), 2022, Strona(/y) e543-e552, ISSN 2666-5247
Wydawca: Elsevier
DOI: 10.1016/s2666-5247(21)00237-8

Transient anti-cytokine autoantibodies superimpose the hyperinflammatory response in Kawasaki disease and multisystem inflammatory syndrome in children: a comparative cohort study on correlates of disease

Autorzy: Stejara A. Netea, Giske Biesbroek, Diana van Stijn, Hanna Ijspeert, Caspar I. van der Made, Machiel H. Jansen, Judy Geissler, J.M. (Merlijn) van den Berg, Martijn van der Kuip, Mariken P. Gruppen, Dieneke Schonenberg-Meinema, Berber Kapitein, A.M. (Marceline) Tutu van Furth, Sietse Q. Nagelkerke, Dasja Pajkrt, Frans B. Plötz, M.E.J. (Lisette) den Boer, Gijs W. Landman, Marlies A. van Houten, Ines
Opublikowane w: eBioMedicine, Numer 95, 2023, Strona(/y) 104736, ISSN 2352-3964
Wydawca: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104736

Mucoricin binding to β-glucan sites on germinating Mucorales spores disrupts neutrophil swarming to promote pathogenicity

Autorzy: Stavroula Baimpa, Matthaios Sertedakis, Elias Drakos, Tonia Akoumianaki, Alexandra Vatikioti, Yiyou Gu, Sanam Dolati, Anastasios Koutsopoulos, Ashraf S. Ibrahim, Georgios Chamilos
Opublikowane w: bioRxiv, Numer October 29, 2026, ISSN 2692-8205
Wydawca: openRxiv
DOI: 10.1101/2025.10.28.685056

Alpha1-antitrypsin impacts innate host–pathogen interactions with Candida albicans by stimulating fungal filamentation

Autorzy: Martin Jaeger; Axel Dietschmann; Sophie Austermeier; Sude Dinçer; Pauline Porschitz; Larsen Vornholz; Ralph J.A. Maas; Evelien G.G. Sprenkeler; Jürgen Ruland; Stefan Wirtz; Tania Azam; Leo A.B. Joosten; Bernhard Hube; Mihai G. Netea; Charles A. Dinarello; Mark S. Gresnigt
Opublikowane w: Virulence, 15, 1, pp. 2333367, Numer 9, 2024, ISSN 2150-5594
Wydawca: Landes Bioscience
DOI: 10.1080/21505594.2024.2333367

Bacteria and fungi of the lung: allies or enemies?

Autorzy: Enrico Garaci, Marilena Pariano, Emilia Nunzi, Claudio Costantini, Marina Maria Bellet, Cinzia Antognelli, Matteo Antonio Russo, Luigina Romani
Opublikowane w: Frontiers in Pharmacology, Numer 15, 2024, Strona(/y) 1497173, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2024.1497173

Targeting immunometabolism in host-directed therapies to fungal disease

Autorzy: Gonçalves SM, Ferreira AV, Cunha C, Carvalho A
Opublikowane w: Clinical Experimental Immunology, Numer Jun 11;208(2), 2022, Strona(/y) 158-166., ISSN 1365-2249
Wydawca: Oxford Academic
DOI: 10.1093/cei/uxab014

Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity

Autorzy: 53. Farnaz Daneshnia, Liuyang Cai, Deepika Gunasekaran, Isha Gautam, Austin Perry, Pegah Mosharaf Ghahfarokhy, Arefeh Ebadati, Julieta Munoz, Dorian Padilla, Süleyha Hilmioglu-Polat, Shenglin Mei, Daniel J. Floyd, Miquel Àngel Schikora-Tamarit, Diego Funtes, Maria Artigués-Lleixà, Louise Walker, Samuel M. Gonçalves, Mostafa Salehi, Agostinho Carvalho, Jigar V. DesaiDavid S. Perlin, Carol Munr
Opublikowane w: Microbiology spectrum, Numer in press, 2025, ISSN 2165-0497
Wydawca: the American Society for Microbiology

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

Autorzy: Christophe d'Enfert, Ann-Kristin Kaune, Leovigildo-Rey Alaban, Sayoni Chakraborty, Nathaniel Cole, Margot Delavy, Daria Kosmala, Benoît Marsaux, Ricardo Fróis-Martins, Moran Morelli, Diletta Rosati, Marisa Valentine, Zixuan Xie, Yoan Emritloll, Peter A Warn, Frédéric Bequet, Marie-Elisabeth Bougnoux, Stephanie Bornes, Mark S Gresnigt, Bernhard Hube, Ilse D Jacobsen, Mélanie Legrand, Salomé L
Opublikowane w: FEMS Microbiology Reviews, Numer 45/3, 2020, Strona(/y) fuaa060, ISSN 1574-6976
Wydawca: -
DOI: 10.1093/femsre/fuaa060

Microbiota-derived metabolites as diagnostic markers for respiratory fungal infections

Autorzy: Anaїs Hérivaux, Samuel M. Gonçalves, Agostinho Carvalho, Cristina Cunha
Opublikowane w: Journal of Pharmaceutical and Biomedical Analysis, Numer 189, 2020, Strona(/y) 113473, ISSN 0731-7085
Wydawca: Elsevier BV
DOI: 10.1016/j.jpba.2020.113473

The development of single-domain VHH nanobodies that target the Candida albicans cell surface

Autorzy: Giuseppe Buda De Cesare, Frank M. Sauer, Anna Kolecka, Aimilia A. Stavrou, Theo C. Verrips, Teun Boekhout, Edward Dolk, Carol A. Munro
Opublikowane w: Microbiology Spectrum, Numer 12, 2024, Strona(/y) e0426923, ISSN 2165-0497
Wydawca: American Society for Microbiology
DOI: 10.1128/spectrum.04269-23

Functional Lipid Analysis via Index-Based Lipidomics Profile: A New Computational Module in LipidOne

Autorzy: H. B. R. Alabed, D. F. Mancini, M. Pergola, L. Romani, S. Martino, A. Koulman, R. M. Pellegrino
Opublikowane w: bioRxiv, Numer in press, 2026, ISSN 2692-8205
Wydawca: openRxiv
DOI: 10.1101/2025.11.04.686489

Lung microbiota predict invasive pulmonary aspergillosis and its outcome in immunocompromised patients

Autorzy: Anaïs Hérivaux, Jesse R Willis, Toine Mercier, Katrien Lagrou, Samuel M Gonçalves, Relber A Gonçales, Johan Maertens, Agostinho Carvalho, Toni Gabaldón, Cristina Cunha
Opublikowane w: Thorax, 2021, Strona(/y) thoraxjnl-2020-216179, ISSN 0040-6376
Wydawca: BMJ Publishing Group
DOI: 10.1136/thoraxjnl-2020-216179

Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan Metabolism

Autorzy: Barbara Cellini, Teresa Zelante, Mirco Dindo, Marina M. Bellet, Giorgia Renga, Luigina Romani, Claudio Costantini
Opublikowane w: International Journal of Molecular Sciences, Numer 21/16, 2020, Strona(/y) 5823, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21165823

Genetic determinants of fungi-induced ROS production are associated with the risk of invasive pulmonary aspergillosis

Autorzy: Matzaraki V, Beno A, Jaeger M, Gresnigt MS, Keur N, Boahen C, Cunha C, Gonçalves SM, Leite L, Lacerda JF, Campos A Jr, van de Veerdonk FL, Joosten L, Netea MG, Carvalho A, Kumar V
Opublikowane w: Redox Biology, Numer Jul 4;55:, 2022, Strona(/y) 102391
Wydawca: Elsevier
DOI: 10.1016/j.redox.2022.102391

COVID-19-associated fungal infections

Autorzy: Hoenigl M, Seidel D, Sprute R, Cunha C, Oliverio M, Goldman GH, Ibrahim AS, Carvalho A
Opublikowane w: Nature Microbiology, Numer Aug;7(8), 2022, Strona(/y) 1127-1140, ISSN 2058-5276
Wydawca: Nature Springer
DOI: 10.1038/s41564-022-01172-2

Future Prospects and Challenges in Mucormycosis Research

Autorzy: Georgios Chamilos, Ulrike Binder, Victoriano Garre
Opublikowane w: Journal of Fungi, Numer 11, 2025, Strona(/y) 545, ISSN 2309-608X
Wydawca: MDPI AG
DOI: 10.3390/jof11080545

A Functional Polymorphism in IL-36β Modulates Macrophage Antifungal Effector Functions and Increases Susceptibility to Invasive Pulmonary Aspergillosis

Autorzy: Samuel M Gonçalves, Luis Leite, Pedro de Vasconcelos, Inês Pereira, Intan M W Dewi, Toine Mercier, Robina Aerts, Dário Ligeiro, Filomena Mendes, Fátima Freitas, Jorge Condeço, Joana Vieira, Eduardo Espada, Katrien Lagrou, Johan A Maertens, Mark S Gresnigt, Charles A Dinarello, João F Lacerda, Carlos Pinho Vaz, Cristina Cunha, Agostinho Carvalho, Frank L van de Veerdonk
Opublikowane w: The Journal of Infectious Diseases, Numer 232, 2025, Strona(/y) 1208-1219, ISSN 0022-1899
Wydawca: University of Chicago Press
DOI: 10.1093/infdis/jiaf301

Regulation of gliotoxin biosynthesis and protection in Aspergillus species

Autorzy: de Castro PA, Colabardini AC, Moraes M, Horta MAC, Knowles SL, Raja HA, Oberlies NH, Koyama Y, Ogawa M, Gomi K, Steenwyk JL, Rokas A, Gonçales RA, Duarte-Oliveira C, Carvalho A, Ries LNA, Goldman GH
Opublikowane w: PLoS Genetics, Numer Jan;18(1), 2022, Strona(/y) e1009965, ISSN 1553-7390
Wydawca: Public Library of Science
DOI: 10.1371/journal.pgen.1009965

Aspergillus fumigatus Acetate Utilization Impacts Virulence Traits and Pathogenicity

Autorzy: Ries LNA, Alves de Castro P, Pereira Silva L, Valero C, Dos Reis TF, Saborano R, Duarte IF, Persinoti GF, Steenwyk JL, Rokas A, Almeida F, Costa JH, Fill T, Sze Wah Wong S, Aimanianda V, Rodrigues FJS
Opublikowane w: mBio, Numer Aug 31;12(4), 2021, Strona(/y) e0168221
Wydawca: American Society of Microbiology
DOI: 10.1128/mbio.01682-21

The immune and microbial homeostasis determines the Candida-mast cells cross-talk in celiac disease

Autorzy: Giorgia Renga, Marilena Pariano, Fiorella D'Onofrio, Giuseppe Pieraccini, Claudia Di Serio, Valeria Rachela Villella, Carlo Abbate, Matteo Puccetti , Stefano Giovagnoli, Claudia Stincardini, Marina Maria Bellet, Maurizio Ricci, Claudio Costantini, Vasileios Oikonomou, Luigina Romani.
Opublikowane w: Life Sci Alliance, Numer 7, 2024, Strona(/y) e202302441, ISSN 2575-1077
Wydawca: -
DOI: 10.26508/lsa.202302441

A shifted composition of the lung microbiota conditions the antifungal response of immunodeficient mice

Autorzy: Emilia Nunzi, Giorgia Renga, Melissa Palmieri, Giuseppe Pieraccini, Marilena Pariano, Claudia Stincardini, Fiorella D’Onofrio, Ilaria Santarelli, Marina Maria Bellet, Andrea Bartoli, Claudio Costantini, Luigina Romani
Opublikowane w: International Journal of Molecular Sciences, Numer Aug 6;22(16), 2021, Strona(/y) 8474, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22168474

sMR and PTX3 levels associate with COVID-19 outcome and survival but not with Long COVID

Autorzy: Lisa Hurler, Federica Mescia, Laura Bergamaschi, Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration, Erika Kajdácsi, György Sinkovits, László Cervenak, Zoltán Prohászka, Paul A. Lyons, and Erik J.M. Toonen.
Opublikowane w: iScience., Numer VOLUME 27, ISSUE 7, 2024, Strona(/y) 110162, ISSN 2589-0042
Wydawca: Cell Press
DOI: 10.1016/j.isci.2024.110162

Paracoccin Overexpression in Paracoccidioides brasiliensis Enhances Fungal Virulence by Remodeling Chitin Properties of the Cell Wall

Autorzy: Gonçales RA, Ricci-Azevedo R, Vieira VCS, Fernandes FF, Thomaz SMO, Carvalho A, Vendruscolo PE, Cunha C, Roque-Barreira MC, Rodrigues F
Opublikowane w: Journal of Infectious Diseases, Numer Jul 2;224(1), 2021, Strona(/y) 164-174, ISSN 1537-6613
Wydawca: Oxford Academic
DOI: 10.1093/infdis/jiaa707

Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis

Autorzy: Gonçales RA, Bastos HN, Duarte-Oliveira C, Antunes D, Sokhatska O, Jacob M, Rolo R, Campos CF, Sasaki SD, Donato A, Mapelli SN, Costa S, Moura CS, Delgado L, Morais A, Torrado E, van de Veerdonk FL, Weichhart T, Lambris JD, Silvestre R, Garlanda C, Mantovani A, Cunha C, Carvalho A
Opublikowane w: American Journal of Respiratory and Critical Care Medicine, Numer Nov 1;206(9):, 2022, Strona(/y) 1140-1152, ISSN 1073-449X
Wydawca: American Thoracic Society
DOI: 10.1164/rccm.202112-2771oc

Humoral pathways of innate immune regulation in granuloma formation

Autorzy: Santos-Ribeiro D, Cunha C, Carvalho A
Opublikowane w: Trends Immunol, Numer 45(6), 2024, Strona(/y) 419-427
Wydawca: Cell Press
DOI: 10.1016/j.it.2024.04.008

From the nose to the lungs: the intricate journey of airborne pathogens amid commensal bacteria

Autorzy: Claudio Costantini, Emilia Nuinzi, Luigina Romani
Opublikowane w: American Physiological Society, Numer Epub 2022 Aug 29, 2022, ISSN 1522-1563
Wydawca: American Physiological Society
DOI: 10.1152/ajpcell.00287.2022

'Mapping' Knowledge Dissemination

Autorzy: Nynke Bos, Lisa Vandeberg, Anke Oerlemans, Marlies Hulscher, W. Gudrun Reijnierse
Opublikowane w: European Journal of Health Communication, Numer 6, 2025, Strona(/y) 60-82, ISSN 2673-5903
Wydawca: University of Zurich, IKMZ – Department of Communication and Media Research
DOI: 10.47368/ejhc.2025.103

Innovative Approaches to Medical Rehabilitation: Regeneration, Immune Training, Homeostasis, and Microbiome Synergy

Autorzy: Enrico Garaci, Matteo Antonio Russo, Marilena Pariano, Matteo Puccetti, Consuelo Fabi, Sarah Balucchi, Marina Maria Bellet, Maurizio Ricci, Massimo Fini, Luigina Romani
Opublikowane w: International Journal of Molecular Sciences, Numer 26, 2025, Strona(/y) 8687, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms26178687

Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis

Autorzy: Laura Seldeslachts, Frederik Staels, Marina Gkountzinopoulou, Cato Jacobs, Birger Tielemans, Eliane Vanhoffelen, Agustin Reséndiz-Sharpe, Lander De Herdt, Jeason Haughton, Teresa Prezzemolo, Oliver Burton, Simon Feys, Frank L. van de Veerdonk, Agostinho Carvalho, Lieve Naesens, Patrick Matthys, Katrien Lagrou, Erik Verbeken, Georgios Chamilos, Joost Wauters, Stephanie Humblet-Baron, Greetje Vande
Opublikowane w: eBioMedicine, Numer 108, 2024, Strona(/y) 105347, ISSN 2352-3964
Wydawca: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105347

Albumin Neutralizes Hydrophobic Toxins and Modulates Candida albicans Pathogenicity

Autorzy: Sophie Austermeier, Marina Pekmezović, Pauline Porschitz, Sejeong Lee, Nessim Kichik, David L. Moyes, Jemima Ho, Natalia K. Kotowicz, Julian R. Naglik, Bernhard Hube, Mark S. Gresnigt
Opublikowane w: mBio, Numer -, 2021, Strona(/y) e0053121, ISSN 2150-7511
Wydawca: -
DOI: 10.1128/mbio.00531-21

Can metaphors in patient information materials improve comprehension and attitudes regarding innovative treatment? The case of personalized immunotherapy for sepsis

Autorzy: Nynke Bos, W. Gudrun Reijnierse, Anke J.M. Oerlemans, Frank L. van de Veerdonk, Mihai G. Netea, Marlies E.J.L. Hulscher, Lisa Vandeberg
Opublikowane w: Patient Education and Counseling, Numer 141, 2026, Strona(/y) 109314, ISSN 0738-3991
Wydawca: Elsevier BV
DOI: 10.1016/j.pec.2025.109314

A signature of differential gene expression in bronchoalveolar lavage fluid predicts mortality in influenza-associated pulmonary aspergillosis

Autorzy: Simon Feys; Jannes Heylen; Agostinho Carvalho; Johan Van Weyenbergh; Joost Wauters; Samuel M. Gonçalves; Cristina Cunha; Yves Debaveye; Greet Hermans; Stephanie Humblet-Baron; Cato Jacobs; Diether La
Opublikowane w: Intensive Care Medicine, Numer 49, 2023, Strona(/y) 2454-257
Wydawca: SPRINGER LINK
DOI: 10.1007/s00134-022-06958-w

Aspergillus fumigatus biology, immunopathogenicity and drug resistance

Autorzy: Frank L. van de Veerdonk, Agostinho Carvalho, Joost Wauters, George Chamilos, Paul E. Verweij
Opublikowane w: Nature Reviews Microbiology, Numer 23, 2025, Strona(/y) 652-666, ISSN 1740-1526
Wydawca: Nature Publishing Group
DOI: 10.1038/s41579-025-01180-z

Editorial: Lung microbiome in health and disease

Autorzy: Kurtis Francis Budden, Luigina Romani
Opublikowane w: Frontiers in Pharmacology, Numer 16, 2025, ISSN 1663-9812
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fphar.2025.1565849

Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response

Autorzy: Delavy, Margot; Sertour, Natacha; Patin, Etienne; Le Chatelier, Emmanuelle; Cole, Nathaniel; Dubois, Florian; Xie, Zixuan; Saint-André, Violaine; Manichanh, Chaysavanh; Walker, Alan; Quintana-Murci, Lluis; Duffy, Darragh; d'Enfert, Christophe; Bougnoux, Marie-Elisabeth; Consortium, Milieu Intérieur
Opublikowane w: Gut Microbes, Numer 13, 2023, Strona(/y) 15(2): 22876, ISSN 1949-0984
Wydawca: -
DOI: 10.1080/19490976.2023.2287618

Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis

Autorzy: Samuel M. Gonçalves, Daniela Antunes, Luis Leite, Toine Mercier, Rob ter Horst, Joana Vieira, Eduardo Espada, Carlos Pinho Vaz, Rosa Branca, Fernando Campilho, Fátima Freitas, Dário Ligeiro, Antón
Opublikowane w: mBio, Numer -, 2021, Strona(/y) Online ahead of print, ISSN 2150-7511
Wydawca: -
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Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosis

Autorzy: Laura Seldeslachts, Sirima Kraisin, Intan M. W. Dewi, Simon Feys, Frederik Staels, Marina Gkountzinopoulou, Cato Jacobs, Birger Tielemans, Eliane Vanhoffelen, Agustin Reséndiz-Sharpe, Lander De Herdt, Oswin Kwan, Niels Vandamme, Jana Roels, Julika Neumann, Teresa Prezzemolo, Bert Malengier-Devlies, Mathias Stroobants, Agostinho Carvalho, Patrick Matthys, Lieve Naesens, Katrien Lagrou, Mona Khan,
Opublikowane w: Science Translational Medicine, Numer 17, 2025, Strona(/y) eadw9578, ISSN 1946-6234
Wydawca: American Association for the Advancement of Science
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Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis

Autorzy: Tonia Akoumianaki, Katerina Vaporidi, Eleni Diamantaki, Frédéric Pène, Remi Beau, Mark S. Gresnigt, Marina Gkountzinopulou, Maria Venichaki, Elias Drakos, Jamel El-Benna, George Samonis, Kieu T.T. Le, Vinod Kumar, Dimitrios Georgopoulos, Frank L. van de Veerdonk, Mihai G. Netea, Jean-Paul Latge, Georgios Chamilos
Opublikowane w: Cell Host & Microbe, Numer S1931-3128(21)00280-8., 2021, ISSN 1931-3128
Wydawca: Cell Press
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Metabolic regulation of the host–fungus interaction: from biological principles to therapeutic opportunities

Autorzy: Rita Silva-Gomes, Inês Caldeira, Raquel Fernandes, Cristina Cunha, Agostinho Carvalho
Opublikowane w: Journal of Leukocyte Biology, Numer 116, 2024, Strona(/y) 469-486, ISSN 1938-3673
Wydawca: Oxford University Press (OUP)
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SARS-CoV-2 Infection is Associated with Age- and Gender-Specific Changes in the Nasopharyngeal Microbiome

Autorzy: Silvia Bozza, Emilia Nunzi, Abel Frias-Mazuecos, Giuseppe Pieraccini , Marilena Pariano , Giorgia Renga, Antonella Mencacci, Vincenzo Nicola Talesa, Cinzia Antognelli, Paolo Puccetti, Luigina Romani, Claudio Costantini.
Opublikowane w: Front Biosci, 2024, Strona(/y) 29:59, ISSN 1093-9946
Wydawca: Frontiers in Bioscience
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A High-Risk Profile for Invasive Fungal Infections Is Associatedwith Altered Nasal Microbiota and Niche Determinants

Autorzy: Claudio Costantini, Emilia Nunzi, Angelica Spolzino, Francesco Merli, Luca Facchini, Antonio Spadea, Lorella Melillo, Katia Codeluppi, Francesco Marchesi, Gessica Marchesini, Daniela Valente, Giulia Dragonetti, Gianpaolo Nadali, Lukas Englmaier, Katerina Coufalikova, Zdeněk Spáčil, Marina Maria Bellet, Marilena Pariano, Giorgia Renga, Claudia Stincardini, Fiorella D'Onofrio,
Opublikowane w: American Society for Microbiology, Numer Apr 21;90(4), 2022, Strona(/y) e0004822, ISSN 1098-5522
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Host albumin redirects Candida albicans metabolism to engage an alternative pathogenicity pathway

Autorzy: Sophia U. J. Hitzler, Candela Fernández-Fernández, Kerstin Günther, Axel Dietschmann, Hrant Hovhannisyan, Anna Möslinger, Sophie Austermeier, Beatriz Cristóvão, Gianluca Vascelli, Teresa Zelante, Marina Pekmezović, Bernardo Ramírez-Zavala, Joachim Morschhäuser, Oliver Werz, Toni Gabaldón, Paul M. Jordan, Slavena Vylkova, Mark S. Gresnigt
Opublikowane w: Nature Communications, Numer 16, 2025, Strona(/y) 6447, ISSN 2041-1723
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Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

Autorzy: Andrea Doni, Raffaella Parente, Ilaria Laface, Elena Magrini, Cristina Cunha, Federico Simone Colombo, João F. Lacerda, António Campos, Sarah N. Mapelli, Francesca Petroni, Rémi Porte, Tilo Schorn, Antonio Inforzato, Toine Mercier, Katrien Lagrou, Johan Maertens, John D. Lambris, Barbara Bottazzi, Cecilia Garlanda, Marina Botto, Agostinho Carvalho, Alberto Mantovani
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A synthetic peptide mimic kills Candida albicans and synergistically prevents infection

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Integrating genetic and immune factors to uncover pathogenetic mechanisms of viral-associated pulmonary aspergillosis

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Albumin orchestrates a natural host defense mechanism against mucormycosis

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Profiling Bacteria in the Lungs of Patients with Severe Influenza Versus COVID-19 with or without Aspergillosis

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Opublikowane w: American Journal of Respiratory and Critical Care Medicine, Numer Epub ahead of print, 2024, ISSN 1073-449X
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In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence

Autorzy: Zoe K. Ross, Sakinah Alsayegh, Yixin Zhao, Steven McPherson, Carol A. Munro, Alexander Lorenz
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Editorial: Advancements in the understanding of Mucorales biology and the management of mucormycosis

Autorzy: Georgios Chamilos, Victoriano Garre
Opublikowane w: Frontiers in Cellular and Infection Microbiology, Numer 14, 2024, Strona(/y) 1427252, ISSN 2235-2988
Wydawca: Frontiers Media S. A.
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